BG17505A3 - METHOD FOR OBTAINING NEW 1- PHENOXY -2- HYDROXY-3- CYCLOALKYLAMINOPROPANES - Google Patents

METHOD FOR OBTAINING NEW 1- PHENOXY -2- HYDROXY-3- CYCLOALKYLAMINOPROPANES

Info

Publication number
BG17505A3
BG17505A3 BG017132A BG1713270A BG17505A3 BG 17505 A3 BG17505 A3 BG 17505A3 BG 017132 A BG017132 A BG 017132A BG 1713270 A BG1713270 A BG 1713270A BG 17505 A3 BG17505 A3 BG 17505A3
Authority
BG
Bulgaria
Prior art keywords
cycloalkylaminopropanes
phenoxy
hydroxy
obtaining new
obtaining
Prior art date
Application number
BG017132A
Other languages
Bulgarian (bg)
Inventor
Herbert Koeppe
Werner Kcmmer
Helmut Staehle
Karl Zeile
Hebresht Engelhardt
Werner Traunecker
Original Assignee
C.H.Boehringer Sohn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H.Boehringer Sohn filed Critical C.H.Boehringer Sohn
Publication of BG17505A3 publication Critical patent/BG17505A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/53—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton
    • E—FIXED CONSTRUCTIONS
    • E04—BUILDING
    • E04H—BUILDINGS OR LIKE STRUCTURES FOR PARTICULAR PURPOSES; SWIMMING OR SPLASH BATHS OR POOLS; MASTS; FENCING; TENTS OR CANOPIES, IN GENERAL
    • E04H13/00—Monuments; Tombs; Burial vaults; Columbaria
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Architecture (AREA)
  • Structural Engineering (AREA)
  • Civil Engineering (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG017132A 1969-07-23 1970-07-24 METHOD FOR OBTAINING NEW 1- PHENOXY -2- HYDROXY-3- CYCLOALKYLAMINOPROPANES BG17505A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1937477A DE1937477C3 (en) 1969-07-23 1969-07-23 I-phenoxy-2-hydroxy-3- (l -methylcycloalkylamino) propane, process for their preparation and medicaments containing them

Publications (1)

Publication Number Publication Date
BG17505A3 true BG17505A3 (en) 1973-11-10

Family

ID=5740681

Family Applications (9)

Application Number Title Priority Date Filing Date
BG017138A BG17508A3 (en) 1969-07-23 1970-03-22 METHOD FOR OBTAINING 1- PHENOXY 2- HYDROXY-3- CYCLOALKYL- AMINOPROPANES
BG017134A BG17750A3 (en) 1969-07-23 1970-03-23 METHOD FOR OBTAINING NEW 1-PHENOXY-2-HYDROXY-3- CYCLOALKYLAMINOPROPANES
BG017137A Expired BG18852A3 (en) 1969-07-23 1970-07-22 METHOD FOR OBTAINING 1-PHENOXY -2- HYDROXY-3- CYCLOACYLAMINO PROPANES
BG017136A BG17507A3 (en) 1969-07-23 1970-07-22 METHOD FOR OBTAINING 1- PHENOXY-2- HYDROXY- 3- CYCLOALKYL AMINOPROPANES
BG015254A BG17749A3 (en) 1969-07-23 1970-07-22 METHOD FOR THE PREPARATION OF PHENOXY-2-HYDROXY -3- CYCLOALKYLAMINOPROPANES
BG017135A BG17751A3 (en) 1969-07-23 1970-07-22 METHOD FOR OBTAINING NEW 1-PHENOXY-2-HYDROXY- -3-CYCLOALKYLAMINOPROPANES
BG018645A BG19132A3 (en) 1969-07-23 1970-07-22 METHOD FOR OBTAINING 1-(2AMINOPHENOXY)-2-HYDROXY-3(1-METHYLCYCLOHEXYLAMINO)PROPANE
BG017132A BG17505A3 (en) 1969-07-23 1970-07-24 METHOD FOR OBTAINING NEW 1- PHENOXY -2- HYDROXY-3- CYCLOALKYLAMINOPROPANES
BG017133A BG17506A3 (en) 1969-07-23 1970-07-24 METHOD FOR OBTAINING 1- PHENOXY-2- HYDROXY-3- CYCLOALKYLAMINO-PROPANES

Family Applications Before (7)

Application Number Title Priority Date Filing Date
BG017138A BG17508A3 (en) 1969-07-23 1970-03-22 METHOD FOR OBTAINING 1- PHENOXY 2- HYDROXY-3- CYCLOALKYL- AMINOPROPANES
BG017134A BG17750A3 (en) 1969-07-23 1970-03-23 METHOD FOR OBTAINING NEW 1-PHENOXY-2-HYDROXY-3- CYCLOALKYLAMINOPROPANES
BG017137A Expired BG18852A3 (en) 1969-07-23 1970-07-22 METHOD FOR OBTAINING 1-PHENOXY -2- HYDROXY-3- CYCLOACYLAMINO PROPANES
BG017136A BG17507A3 (en) 1969-07-23 1970-07-22 METHOD FOR OBTAINING 1- PHENOXY-2- HYDROXY- 3- CYCLOALKYL AMINOPROPANES
BG015254A BG17749A3 (en) 1969-07-23 1970-07-22 METHOD FOR THE PREPARATION OF PHENOXY-2-HYDROXY -3- CYCLOALKYLAMINOPROPANES
BG017135A BG17751A3 (en) 1969-07-23 1970-07-22 METHOD FOR OBTAINING NEW 1-PHENOXY-2-HYDROXY- -3-CYCLOALKYLAMINOPROPANES
BG018645A BG19132A3 (en) 1969-07-23 1970-07-22 METHOD FOR OBTAINING 1-(2AMINOPHENOXY)-2-HYDROXY-3(1-METHYLCYCLOHEXYLAMINO)PROPANE

Family Applications After (1)

Application Number Title Priority Date Filing Date
BG017133A BG17506A3 (en) 1969-07-23 1970-07-24 METHOD FOR OBTAINING 1- PHENOXY-2- HYDROXY-3- CYCLOALKYLAMINO-PROPANES

Country Status (17)

Country Link
US (1) US3755413A (en)
JP (5) JPS5133106B1 (en)
AT (9) AT304474B (en)
BE (1) BE753774A (en)
BG (9) BG17508A3 (en)
CH (10) CH570363A5 (en)
CS (9) CS170524B2 (en)
DE (1) DE1937477C3 (en)
DK (1) DK140281B (en)
ES (8) ES382014A1 (en)
FR (1) FR2059551B1 (en)
GB (1) GB1314896A (en)
NL (1) NL169874C (en)
PL (9) PL79772B1 (en)
RO (9) RO59159A (en)
SE (1) SE370391B (en)
YU (5) YU34395B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3937706A (en) * 1969-07-23 1976-02-10 Boehringer Ingelheim Gmbh 1-(2'ethynyl-phenoxy)-2-hydroxy-3-(cycloalkyl-amino)-propanes and salts thereof
US4021576A (en) * 1969-07-23 1977-05-03 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing a 1-(2'-ethynyl-phenoxy)-2-hydroxy-3-(cycloalkyl-amino)-propane and method of use
US4038313A (en) * 1970-01-08 1977-07-26 Ciba-Geigy Corporation Cycloalkylureido phenoxy propanolamines
US4120978A (en) * 1970-01-08 1978-10-17 Ciba-Geigy Corporation Pharmaceutical composition for inhibiting and blocking cardioselective beta-receptors
SE354851B (en) * 1970-02-18 1973-03-26 Haessle Ab
US4145442A (en) * 1972-04-04 1979-03-20 Aktiebolaget Hassle Phenoxy-hydroxypropylamines, their preparation, and method and pharmaceutical preparations for treating cardiovascular diseases
US4038414A (en) * 1972-06-08 1977-07-26 Ciba-Geigy Corporation Amines and processes for their manufacture
US4035420A (en) * 1972-07-06 1977-07-12 Aktiebolaget Hassle Substituted ureido alkylene phenoxy propanolamines
DE2309887C2 (en) * 1973-02-28 1983-11-10 C.H. Boehringer Sohn, 6507 Ingelheim 1-aryloxy-2-hydroxy-3-alkynylaminopropane derivatives and their physiologically acceptable acid addition salts, pharmaceutical preparations and manufacturing processes for the compounds
US4220659A (en) * 1974-02-22 1980-09-02 Boehringer Ingelheim Gmbh 1-Phenoxy-2-hydroxy-3-alkynylamino-propanes and salts thereof
SE7510153L (en) * 1974-09-12 1976-05-07 American Cyanamid Co ALKANOLAMINES
US4165384A (en) * 1974-11-01 1979-08-21 Aktiebolaget Hassle Amide substituted phenoxy propanol amines
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4471127A (en) * 1981-09-08 1984-09-11 Ciba-Geigy Corporation 1-5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols
US5039801A (en) * 1985-12-20 1991-08-13 The United States Of America As Represented By The Department Of Health & Human Services Thermal fragmentation of methylbenzylurea disastereomers or secondary amines and preparation of optically active secondary amines
JPS6364630U (en) * 1986-10-17 1988-04-28

Also Published As

Publication number Publication date
CS170524B2 (en) 1976-08-27
PL90026B1 (en) 1976-12-31
NL169874B (en) 1982-04-01
CS170525B2 (en) 1976-08-27
YU34663B (en) 1979-12-31
YU34396B (en) 1979-07-10
YU34395B (en) 1979-07-10
AT304477B (en) 1973-01-10
RO59210A (en) 1976-01-15
PL79772B1 (en) 1975-06-30
CH537360A (en) 1973-05-31
US3755413A (en) 1973-08-28
YU255175A (en) 1978-06-30
BG17507A3 (en) 1973-11-10
YU254575A (en) 1979-04-30
JPS5210862B1 (en) 1977-03-26
CH536811A (en) 1973-06-29
CH536809A (en) 1973-06-29
DE1937477C3 (en) 1980-04-10
BG19132A3 (en) 1975-04-30
YU186070A (en) 1978-12-31
BG17751A3 (en) 1973-12-25
PL90028B1 (en) 1976-12-31
NL7010928A (en) 1971-01-26
JPS5210863B1 (en) 1977-03-26
AT306702B (en) 1973-04-25
AT304476B (en) 1973-01-10
FR2059551B1 (en) 1974-09-20
SE370391B (en) 1974-10-14
CH536813A (en) 1973-06-29
AT306704B (en) 1973-04-25
BG17506A3 (en) 1973-11-10
CH570363A5 (en) 1975-12-15
AT304478B (en) 1973-01-10
RO59089A (en) 1975-11-15
BG17749A3 (en) 1973-12-25
YU254475A (en) 1978-12-31
ES394913A1 (en) 1974-12-16
CS170527B2 (en) 1976-08-27
JPS5133106B1 (en) 1976-09-17
RO59159A (en) 1976-02-15
YU34662B (en) 1979-12-31
AT306703B (en) 1973-04-25
PL90039B1 (en) 1976-12-31
ES394915A1 (en) 1974-12-16
CH550140A (en) 1974-06-14
RO59112A (en) 1976-01-15
AT304475B (en) 1973-01-10
CS170528B2 (en) 1976-08-27
RO59209A (en) 1976-01-15
RO59211A (en) 1976-01-15
RO60111A (en) 1976-06-15
FR2059551A1 (en) 1971-06-04
BG17750A3 (en) 1973-12-25
ES394916A1 (en) 1974-12-16
DK140281B (en) 1979-07-23
CH536812A (en) 1973-06-29
RO56318A (en) 1974-09-01
CS170530B2 (en) 1976-08-27
ES394919A1 (en) 1974-12-01
RO60112A (en) 1976-08-15
NL169874C (en) 1982-09-01
DE1937477B2 (en) 1979-08-02
JPS5238556B1 (en) 1977-09-29
BG17508A3 (en) 1973-11-10
ES394918A1 (en) 1974-12-01
PL90029B1 (en) 1976-12-31
YU254675A (en) 1979-04-30
ES394914A1 (en) 1974-12-01
JPS5210861B1 (en) 1977-03-26
CS170529B2 (en) 1976-08-27
CS170526B2 (en) 1976-08-27
BG18852A3 (en) 1975-03-20
PL90030B1 (en) 1976-12-31
CH575376A5 (en) 1976-05-14
YU34113B (en) 1978-12-31
AT303706B (en) 1972-12-11
CH536810A (en) 1973-06-29
AT304474B (en) 1973-01-10
GB1314896A (en) 1973-04-26
PL90038B1 (en) 1976-12-31
DE1937477A1 (en) 1971-02-04
CS170531B2 (en) 1976-08-27
CH550139A (en) 1974-06-14
DK140281C (en) 1979-12-10
ES394917A1 (en) 1974-12-01
PL90027B1 (en) 1976-12-31
BE753774A (en) 1971-01-22
ES382014A1 (en) 1973-06-16
PL90025B1 (en) 1976-12-31
CS170532B2 (en) 1976-08-27

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