BG107888A - Нови "ибробла''ни ра''...жни "ак'ори - Google Patents
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- BG107888A BG107888A BG107888A BG10788803A BG107888A BG 107888 A BG107888 A BG 107888A BG 107888 A BG107888 A BG 107888A BG 10788803 A BG10788803 A BG 10788803A BG 107888 A BG107888 A BG 107888A
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Psychology (AREA)
- Transplantation (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25183700P | 2000-12-08 | 2000-12-08 | |
| US10/005,646 US20020151496A1 (en) | 2000-12-08 | 2001-12-07 | Novel fibroblast growth factors |
| PCT/US2001/047350 WO2002046424A2 (en) | 2000-12-08 | 2001-12-10 | Fibroblast growth factors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG107888A true BG107888A (bg) | 2004-08-31 |
Family
ID=26674594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG107888A BG107888A (bg) | 2000-12-08 | 2003-06-06 | Нови "ибробла''ни ра''...жни "ак'ори |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20020151496A1 (ru) |
| EP (1) | EP1389237A2 (ru) |
| JP (1) | JP2005506275A (ru) |
| KR (1) | KR20040052442A (ru) |
| CN (1) | CN1518597A (ru) |
| AU (1) | AU2603402A (ru) |
| BG (1) | BG107888A (ru) |
| BR (1) | BR0116507A (ru) |
| CA (1) | CA2431374A1 (ru) |
| CZ (1) | CZ20031570A3 (ru) |
| EE (1) | EE200300269A (ru) |
| HU (1) | HUP0400657A1 (ru) |
| IL (1) | IL156259A0 (ru) |
| MX (1) | MXPA03005142A (ru) |
| NO (1) | NO20032573L (ru) |
| PL (1) | PL366158A1 (ru) |
| RU (1) | RU2329058C2 (ru) |
| SI (1) | SI21372A (ru) |
| SK (1) | SK7012003A3 (ru) |
| WO (1) | WO2002046424A2 (ru) |
| ZA (1) | ZA200305236B (ru) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7253266B2 (en) | 1999-07-27 | 2007-08-07 | Curagen Corporation | Polypeptides of FGF-CX |
| US6982250B2 (en) | 2000-11-06 | 2006-01-03 | Curagen Corporation | Methods of prevention and treatment of inflammatory bowel disease |
| US7189693B2 (en) | 2000-11-06 | 2007-03-13 | Curagen Corporation | Treatment of inflammatory bowel disease using fibroblast growth factor CX polypeptides |
| US20050176631A1 (en) * | 2002-01-15 | 2005-08-11 | Heuer Josef G. | Method for reducing morbidity and mortality in critically ill patients |
| DE602004029337D1 (de) * | 2003-04-01 | 2010-11-11 | Us Dept Of Veteran S Affaires | Auf stammzellen, vorläuferzellen oder targetzellen basierende behandlung von multiorganversagen. |
| WO2004105787A1 (en) * | 2003-05-28 | 2004-12-09 | The University Of Kyoto | Methods of using combinations of egf-2 and egf-20 to treat central nervous system disorders |
| US8951966B2 (en) | 2011-07-01 | 2015-02-10 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants and fusions of FGF19 polypeptides, and uses and methods thereof for treatment of metabolic disorders and diseases |
| US9290557B2 (en) | 2012-11-28 | 2016-03-22 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants and fusions of FGF19 polypeptides |
| ES2828505T3 (es) | 2012-11-28 | 2021-05-26 | Ngm Biopharmaceuticals Inc | Composiciones y métodos para el tratamiento de trastornos y enfermedades metabólicos |
| US9273107B2 (en) | 2012-12-27 | 2016-03-01 | Ngm Biopharmaceuticals, Inc. | Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
| IL292303A (en) | 2012-12-27 | 2022-06-01 | Ngm Biopharmaceuticals Inc | Methods of regulating bile acid homeostasis and treatment of bile acid disorders and diseases |
| EP3062881B1 (en) | 2013-10-28 | 2019-10-02 | NGM Biopharmaceuticals, Inc. | Cancer models and associated methods |
| JP6837840B2 (ja) | 2014-01-24 | 2021-03-10 | エヌジーエム バイオファーマシューティカルス，インコーポレーテッド | 結合タンパク質及びその使用方法 |
| US10398758B2 (en) | 2014-05-28 | 2019-09-03 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants of FGF19 polypeptides and uses thereof for the treatment of hyperglycemic conditions |
| EP3155005A4 (en) | 2014-06-16 | 2018-07-11 | NGM Biopharmaceuticals, Inc. | Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
| US10517929B2 (en) | 2014-10-23 | 2019-12-31 | Ngm Biopharmaceuticals, Inc. | Pharmaceutical compositions comprising FGF19 variants |
| WO2016073855A1 (en) | 2014-11-07 | 2016-05-12 | Ngm Biopharmaceuticals, Inc. | Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders |
| US10800843B2 (en) | 2015-07-29 | 2020-10-13 | Ngm Biopharmaceuticals, Inc. | Beta klotho-binding proteins |
| JP6728352B2 (ja) | 2015-11-09 | 2020-07-22 | エヌジーエム バイオファーマシューティカルス，インコーポレーテッド | 胆汁酸に関係した障害の治療方法 |
| US11370841B2 (en) | 2016-08-26 | 2022-06-28 | Ngm Biopharmaceuticals, Inc. | Methods of treating fibroblast growth factor 19-mediated cancers and tumors |
| CN107050428B (zh) * | 2017-03-23 | 2020-05-05 | 温州医科大学 | Fgf20药物及其对脑创伤的治疗应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000060085A1 (en) * | 1999-04-02 | 2000-10-12 | Millennium Pharmaceuticals, Inc. | Fibroblast growth factor-20 |
| EP1224283A2 (en) * | 1999-10-22 | 2002-07-24 | Chiron Corporation | Human and rat fgf-20 genes and gene expression products |
| ES2335386T3 (es) * | 1999-11-18 | 2010-03-26 | Novartis Vaccines And Diagnostics, Inc. | Gen fgf-21 humano y productos de expresion genica. |
| AU2001262934A1 (en) * | 2000-06-01 | 2001-12-11 | Eli Lilly And Company | Human fgf-20 nucleic acids and polypeptides |
| AU2001271811B2 (en) * | 2000-07-03 | 2006-07-20 | Curagen Corporation | Novel fibroblast growth factors and nucleic acids encoding same |
-
2001
- 2001-12-07 US US10/005,646 patent/US20020151496A1/en not_active Abandoned
- 2001-12-10 WO PCT/US2001/047350 patent/WO2002046424A2/en active IP Right Grant
- 2001-12-10 EE EEP200300269A patent/EE200300269A/xx unknown
- 2001-12-10 IL IL15625901A patent/IL156259A0/xx unknown
- 2001-12-10 EP EP01995460A patent/EP1389237A2/en active Pending
- 2001-12-10 BR BR0116507-0A patent/BR0116507A/pt not_active IP Right Cessation
- 2001-12-10 PL PL01366158A patent/PL366158A1/xx not_active Application Discontinuation
- 2001-12-10 JP JP2002548141A patent/JP2005506275A/ja active Pending
- 2001-12-10 CA CA002431374A patent/CA2431374A1/en not_active Abandoned
- 2001-12-10 CZ CZ20031570A patent/CZ20031570A3/cs unknown
- 2001-12-10 SK SK701-2003A patent/SK7012003A3/sk unknown
- 2001-12-10 MX MXPA03005142A patent/MXPA03005142A/es not_active Application Discontinuation
- 2001-12-10 RU RU2003119657/14A patent/RU2329058C2/ru not_active IP Right Cessation
- 2001-12-10 SI SI200120066A patent/SI21372A/sl not_active IP Right Cessation
- 2001-12-10 AU AU2603402A patent/AU2603402A/xx active Pending
- 2001-12-10 KR KR10-2003-7007614A patent/KR20040052442A/ko not_active Application Discontinuation
- 2001-12-10 HU HU0400657A patent/HUP0400657A1/hu unknown
- 2001-12-10 CN CNA018202993A patent/CN1518597A/zh active Pending
-
2003
- 2003-06-06 BG BG107888A patent/BG107888A/bg unknown
- 2003-06-06 NO NO20032573A patent/NO20032573L/no not_active Application Discontinuation
- 2003-07-07 ZA ZA2003/05236A patent/ZA200305236B/en unknown
-
2007
- 2007-06-22 US US11/821,191 patent/US20080057076A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2431374A1 (en) | 2002-06-13 |
| US20080057076A1 (en) | 2008-03-06 |
| EE200300269A (et) | 2003-10-15 |
| RU2329058C2 (ru) | 2008-07-20 |
| NO20032573D0 (no) | 2003-06-06 |
| ZA200305236B (en) | 2005-06-29 |
| AU2603402A (en) | 2002-06-18 |
| US20020151496A1 (en) | 2002-10-17 |
| CN1518597A (zh) | 2004-08-04 |
| BR0116507A (pt) | 2004-01-06 |
| PL366158A1 (en) | 2005-01-24 |
| RU2003119657A (ru) | 2005-02-27 |
| WO2002046424A2 (en) | 2002-06-13 |
| IL156259A0 (en) | 2004-01-04 |
| CZ20031570A3 (cs) | 2004-01-14 |
| JP2005506275A (ja) | 2005-03-03 |
| HUP0400657A1 (en) | 2006-04-28 |
| AU2002226034A2 (en) | 2002-06-18 |
| EP1389237A2 (en) | 2004-02-18 |
| WO2002046424A3 (en) | 2003-11-27 |
| SK7012003A3 (en) | 2004-04-06 |
| KR20040052442A (ko) | 2004-06-23 |
| NO20032573L (no) | 2003-07-22 |
| MXPA03005142A (es) | 2004-10-15 |
| SI21372A (sl) | 2004-06-30 |
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