BG107594A - 17-метиленстероиди, метод за тяхното получаване ифармацевтични състави, които съдържат тези съединения - Google Patents

17-метиленстероиди, метод за тяхното получаване ифармацевтични състави, които съдържат тези съединения Download PDF

Info

Publication number
BG107594A
BG107594A BG107594A BG10759403A BG107594A BG 107594 A BG107594 A BG 107594A BG 107594 A BG107594 A BG 107594A BG 10759403 A BG10759403 A BG 10759403A BG 107594 A BG107594 A BG 107594A
Authority
BG
Bulgaria
Prior art keywords
chloro
ester
pseudohalogen
general formula
hydrogen atom
Prior art date
Application number
BG107594A
Other languages
Bulgarian (bg)
English (en)
Inventor
Bernd Menzenbach
Walter Elger
Peter Droescher
Alexander Hillisch
Guenter Kaufmann
Hans-Udo Schweikert
Gerd Muller
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of BG107594A publication Critical patent/BG107594A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG107594A 2000-09-04 2003-02-27 17-метиленстероиди, метод за тяхното получаване ифармацевтични състави, които съдържат тези съединения BG107594A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10043846A DE10043846A1 (de) 2000-09-04 2000-09-04 17-Methylensteroide, Verfahren zu deren Herstellung und diese Verbindung enthaltende pharmazeutische Zusammensetzungen
PCT/EP2001/009943 WO2002019971A1 (de) 2000-09-04 2001-08-29 4-halogenierte 17-methylensteroide, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen

Publications (1)

Publication Number Publication Date
BG107594A true BG107594A (bg) 2003-09-30

Family

ID=7655148

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107594A BG107594A (bg) 2000-09-04 2003-02-27 17-метиленстероиди, метод за тяхното получаване ифармацевтични състави, които съдържат тези съединения

Country Status (29)

Country Link
EP (1) EP1423407B1 (et)
JP (1) JP2004513084A (et)
KR (1) KR100530816B1 (et)
CN (1) CN1262560C (et)
AT (1) ATE319733T1 (et)
AU (2) AU2002210470B2 (et)
BG (1) BG107594A (et)
BR (1) BR0113618A (et)
CA (1) CA2421302C (et)
DE (2) DE10043846A1 (et)
DK (1) DK1423407T3 (et)
EA (1) EA006387B1 (et)
EE (1) EE05186B1 (et)
ES (1) ES2260294T3 (et)
HK (1) HK1060135A1 (et)
HR (1) HRP20030256A2 (et)
HU (1) HUP0300936A3 (et)
IL (2) IL154666A0 (et)
ME (1) MEP14408A (et)
MX (1) MXPA03001912A (et)
NO (1) NO325012B1 (et)
NZ (1) NZ524485A (et)
PL (1) PL360669A1 (et)
PT (1) PT1423407E (et)
RS (1) RS50305B (et)
SK (1) SK286757B6 (et)
UA (1) UA74592C2 (et)
WO (1) WO2002019971A1 (et)
ZA (1) ZA200301715B (et)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10141984A1 (de) * 2001-08-28 2003-03-20 Jenapharm Gmbh Neue 17-Methylen-4-azasteroide
US7199115B2 (en) 2004-04-19 2007-04-03 Schering Ag 17α-fluorosteroids, pharmaceutical compositions containing 17α-fluorosteroids and a method of making them
AT12800U1 (de) * 2007-11-05 2012-11-15 Bayer Schering Pharma Ag Pharmazeutisches Präparat zur Verwendung bei der oralen Kontrazeption von Frauen mit Laktoseintoleranz

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2611773A (en) * 1951-08-21 1952-09-23 Upjohn Co Estradiol 17-cyclopenetanepropionate
US3146239A (en) * 1957-09-23 1964-08-25 Syntex Corp 4-halo-19-nor-progesterone
US3232960A (en) * 1959-10-08 1966-02-01 Upjohn Co 3-keto-4-fluoro- and 3-keto-4,4-difluorosteroids and process
US3661940A (en) * 1970-04-13 1972-05-09 Sandoz Ag Derivatives of 21-methyl-19-norpregnanes
US4389345A (en) * 1981-10-09 1983-06-21 G.D. Searle & Co. 3-Oxoestra-17-acetonitrile and unsaturated analogs
US5994334A (en) * 1997-02-05 1999-11-30 University Of Maryland Androgen synthesis inhibitors
WO2002000681A1 (en) * 2000-06-27 2002-01-03 Aventis Pharma S.A. 20-fluoro-17(20)-vinyl steroids as inhibitors of c17-20-lyase and 5-alpha reductase

Also Published As

Publication number Publication date
WO2002019971A1 (de) 2002-03-14
SK2442003A3 (en) 2003-08-05
DE50109175D1 (de) 2006-05-04
SK286757B6 (sk) 2009-05-07
ZA200301715B (en) 2004-08-13
CN1452628A (zh) 2003-10-29
NO325012B1 (no) 2008-01-14
PL360669A1 (en) 2004-09-20
WO2002019971A9 (de) 2002-08-08
HUP0300936A2 (hu) 2003-11-28
MEP14408A (en) 2010-06-10
EE05186B1 (et) 2009-06-15
HUP0300936A3 (en) 2010-01-28
BR0113618A (pt) 2003-07-15
RS50305B (sr) 2009-09-08
MXPA03001912A (es) 2004-07-08
EA200300322A1 (ru) 2003-10-30
CA2421302A1 (en) 2003-03-03
PT1423407E (pt) 2006-07-31
DK1423407T3 (da) 2006-07-03
UA74592C2 (en) 2006-01-16
IL154666A (en) 2008-12-29
KR100530816B1 (ko) 2005-11-25
DE10043846A1 (de) 2002-04-04
YU16403A (sh) 2006-05-25
EA006387B1 (ru) 2005-12-29
EE200300087A (et) 2005-02-15
HRP20030256A2 (en) 2005-10-31
CA2421302C (en) 2007-08-14
NO20030989L (no) 2003-05-02
EP1423407A1 (de) 2004-06-02
AU2002210470B2 (en) 2006-07-20
IL154666A0 (en) 2003-09-17
KR20030028836A (ko) 2003-04-10
AU1047002A (en) 2002-03-22
NZ524485A (en) 2005-11-25
NO20030989D0 (no) 2003-03-03
ATE319733T1 (de) 2006-03-15
EP1423407B1 (de) 2006-03-08
JP2004513084A (ja) 2004-04-30
ES2260294T3 (es) 2006-11-01
HK1060135A1 (en) 2004-07-30
CN1262560C (zh) 2006-07-05

Similar Documents

Publication Publication Date Title
US6855836B2 (en) 17-Methylene steroids, process for their production and pharmaceutical compositions that contain these compounds
EP1272504B1 (de) 8.beta.-hydrocarbyl-substituierte estratriene als selektiv wirksame estrogene
EA002623B1 (ru) 11β-ГАЛОГЕН-7α-ЗАМЕЩЕННЫЕ ЭСТРАТРИЕНЫ, СПОСОБ ПОЛУЧЕНИЯ ФАРМАЦЕВТИЧЕСКИХ ПРЕПАРАТОВ, СОДЕРЖАЩИХ ЭТИ 11β-ГАЛОГЕН-7α-ЗАМЕЩЕННЫЕ ЭСТРАТРИЕНЫ, И ИХ ПРИМЕНЕНИЕ ДЛЯ ИЗГОТОВЛЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ
US8492570B2 (en) 2-substituted estra-1,3,5(10)-triene-3-yl sulfamate with an anti-tumor action
FI81361C (fi) Foerfarande foer framstaellning av terapeutiskt aktiva 1-alkyl-androsta-1,4-dien-3,17-dioner.
JPS6220998B2 (et)
NO329563B1 (no) 9-alfa-substituerte ostratriener som selektivt aktive ostrogener, farmasoytiske preparater som inneholder forbindelsene, samt anvendelse derav til fremstilling av farmasoytiske midler
US7199115B2 (en) 17α-fluorosteroids, pharmaceutical compositions containing 17α-fluorosteroids and a method of making them
EP1226155B1 (de) 18-nor-steroide als selektiv wirksame estrogene
BG107594A (bg) 17-метиленстероиди, метод за тяхното получаване ифармацевтични състави, които съдържат тези съединения
JPS6355488B2 (et)
IL41454A (en) 3-keto-7(alpha,bela)-loweralkyl-delta5-androstanes and process for preparing same
JP2007532688A (ja) １７α−フルオロ−１７β−ヒドロキシイミノメチルステロイド、それらを製造する方法および前記化合物を含んでなる医薬組成物
DE10019167A1 (de) Substituierte Estratriene als selektiv wirksame Estrogene
JP2006524202A (ja) ８β−ビニル−１１β（ω−置換された）アルキル−エストラ−１，３，５（１０）−トリエン
FI84487B (fi) 1-alkyl-androsta-1,4-dien-3, 17-dioner som anvaends foer kontraseption och en komposition innehaollande desamma.
DE19954105A1 (de) 18-Nor-Steroide als selektiv wirksame Estrogene