BG107510A - Карбоксамидни съединения и тяхното използване като антагонисти на човешки 11 cby рецептор - Google Patents
Карбоксамидни съединения и тяхното използване като антагонисти на човешки 11 cby рецептор Download PDFInfo
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- BG107510A BG107510A BG107510A BG10751003A BG107510A BG 107510 A BG107510 A BG 107510A BG 107510 A BG107510 A BG 107510A BG 10751003 A BG10751003 A BG 10751003A BG 107510 A BG107510 A BG 107510A
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- phenyl
- ethoxy
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- benzamide
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- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Virology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Anesthesiology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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GBGB0018758.3A GB0018758D0 (en) | 2000-07-31 | 2000-07-31 | Novel use and compunds |
GB0112544A GB0112544D0 (en) | 2001-05-23 | 2001-05-23 | Novel use and compounds |
PCT/EP2001/008637 WO2002010146A1 (en) | 2000-07-31 | 2001-07-26 | Carboxamide compounds and their use as antagonists of a human 11cby receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
BG107510A true BG107510A (bg) | 2003-09-30 |
Family
ID=26244767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG107510A BG107510A (bg) | 2000-07-31 | 2003-01-30 | Карбоксамидни съединения и тяхното използване като антагонисти на човешки 11 cby рецептор |
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---|---|
EP (1) | EP1305304A1 (no) |
JP (1) | JP2004505070A (no) |
KR (1) | KR20030059084A (no) |
CN (1) | CN1444573A (no) |
AP (1) | AP2003002720A0 (no) |
AU (1) | AU2001278508A1 (no) |
BG (1) | BG107510A (no) |
BR (1) | BR0112856A (no) |
CA (1) | CA2417638A1 (no) |
CZ (1) | CZ2003297A3 (no) |
EA (1) | EA200300064A1 (no) |
HU (1) | HUP0302966A2 (no) |
IL (1) | IL153645A0 (no) |
MA (1) | MA25829A1 (no) |
MX (1) | MXPA03000923A (no) |
NO (1) | NO20030471L (no) |
OA (1) | OA12346A (no) |
PL (1) | PL365183A1 (no) |
SK (1) | SK1142003A3 (no) |
WO (1) | WO2002010146A1 (no) |
Families Citing this family (32)
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AU2003222648A1 (en) * | 2002-05-13 | 2003-12-02 | Eli Lilly And Company | Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes |
US7141561B2 (en) | 2002-07-25 | 2006-11-28 | Sanofi-Aventis Deutschland Gmbh | Substituted diaryl heterocycles, process for their preparation and their use as medicaments |
DE10233817A1 (de) * | 2002-07-25 | 2004-02-12 | Aventis Pharma Deutschland Gmbh | Substituierte Diarylheterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
US7223788B2 (en) | 2003-02-14 | 2007-05-29 | Sanofi-Aventis Deutschland Gmbh | Substituted N-aryl heterocycles, process for their preparation and their use as medicaments |
DE10306250A1 (de) * | 2003-02-14 | 2004-09-09 | Aventis Pharma Deutschland Gmbh | Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
ES2350837T3 (es) * | 2003-05-01 | 2011-01-27 | Bristol-Myers Squibb Company | Compuestos de pirazol-amida sustituidos con arilo útiles como inhibidores de quinasas. |
KR101204247B1 (ko) | 2003-07-22 | 2012-11-22 | 아스텍스 테라퓨틱스 리미티드 | 3,4-이치환된 1h-피라졸 화합물 및 그의 시클린 의존성키나제 (cdk) 및 글리코겐 합성효소 키나제-3(gsk-3) 조정제로서 용도 |
US7037927B2 (en) | 2003-10-16 | 2006-05-02 | Abbott Laboratories | Amides that inhibit vanilloid receptor subtype 1 (VR1) receptor |
US7319108B2 (en) | 2004-01-25 | 2008-01-15 | Sanofi-Aventis Deutschland Gmbh | Aryl-substituted heterocycles, process for their preparation and their use as medicaments |
US7241787B2 (en) | 2004-01-25 | 2007-07-10 | Sanofi-Aventis Deutschland Gmbh | Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments |
EP1720826A4 (en) * | 2004-03-02 | 2007-10-31 | Neurogen Corp | HETEROALKYL SUBSTITUTED BIPHENYL-4-CARBOXYL ACRYLAMIDE ANALOG |
US7605176B2 (en) | 2004-03-06 | 2009-10-20 | Boehringer Ingelheim International Gmbh | β-ketoamide compounds with MCH antagonistic activity |
DE102004010893A1 (de) * | 2004-03-06 | 2005-09-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue ß-Ketoamid-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
TW200613272A (en) | 2004-08-13 | 2006-05-01 | Astrazeneca Ab | Isoindolone compounds and their use as metabotropic glutamate receptor potentiators |
DE102004039789A1 (de) * | 2004-08-16 | 2006-03-02 | Sanofi-Aventis Deutschland Gmbh | Arylsubstituierte polycyclische Amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
AR054425A1 (es) | 2005-01-21 | 2007-06-27 | Astex Therapeutics Ltd | Sales de adicion de piperidin 4-il- amida de acido 4-(2,6-dicloro-benzoilamino) 1h-pirazol-3-carboxilico. |
US8404718B2 (en) | 2005-01-21 | 2013-03-26 | Astex Therapeutics Limited | Combinations of pyrazole kinase inhibitors |
US7807706B2 (en) | 2005-08-12 | 2010-10-05 | Astrazeneca Ab | Metabotropic glutamate-receptor-potentiating isoindolones |
AR056155A1 (es) | 2005-10-26 | 2007-09-19 | Bristol Myers Squibb Co | Antagonistas del receptor 1 de la hormona de concentracion de melanina no basica |
US7553836B2 (en) | 2006-02-06 | 2009-06-30 | Bristol-Myers Squibb Company | Melanin concentrating hormone receptor-1 antagonists |
BRPI0707836A2 (pt) | 2006-02-15 | 2011-05-10 | Sanofi Aventis | arildiidroisoquinolininas aminoÁlcool substituÍdas, processo para sua preparaÇço e seu uso como medicamento, medicamento e processo para sua produÇço |
GB0625523D0 (en) * | 2006-12-21 | 2007-01-31 | Ge Healthcare Ltd | In vivo imaging agents |
TWI417100B (zh) | 2007-06-07 | 2013-12-01 | Astrazeneca Ab | 二唑衍生物及其作為代謝型麩胺酸受體增效劑-842之用途 |
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
PE20091928A1 (es) | 2008-05-29 | 2009-12-31 | Bristol Myers Squibb Co | Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos |
US7790760B2 (en) | 2008-06-06 | 2010-09-07 | Astrazeneca Ab | Metabotropic glutamate receptor isoxazole ligands and their use as potentiators 286 |
AR072297A1 (es) | 2008-06-27 | 2010-08-18 | Novartis Ag | Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona. |
CA2739488A1 (en) | 2008-10-15 | 2010-04-22 | Boehringer Ingelheim International Gmbh | Fused heteroaryl diamide compounds useful as mmp-13 inhibitors |
US8785489B2 (en) | 2008-10-17 | 2014-07-22 | Boehringer Ingelheim International Gmbh | Heteroaryl substituted indole compounds useful as MMP-13 inhibitors |
UY32442A (es) | 2009-02-13 | 2010-09-30 | Sanofi Aventis | Nuevos indanos sustituidos, procesos para su preparacion y uso de los mismos como un medicamento |
AR075402A1 (es) | 2009-02-13 | 2011-03-30 | Sanofi Aventis | Derivados heterociclicos oxigenados y/o nitrogenados de tetrahidronaftaleno, medicamentos que los contienen y uso de los mismos en el tratamiento de trastornos metabolicos, tales como obesidad,entre otros. |
CA2866080C (en) * | 2012-03-01 | 2021-01-19 | University Of Cincinnati | Ros-activated compounds as selective anti-cancer therapeutics |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
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ZA985542B (en) * | 1997-07-03 | 1999-04-07 | Smithkline Beecham Corp | Substituted benzanilides as CCR5 receptor ligands antiinflammatory agents and antiviral agents |
AU5239299A (en) * | 1998-07-28 | 2000-02-21 | Smithkline Beecham Corporation | Substituted anilide compounds and methods |
MXPA01008142A (es) * | 1999-02-10 | 2003-07-21 | Welfide Corp | Compuestos de amida, y uso medicinal de los mismos. |
-
2001
- 2001-07-26 BR BR0112856-6A patent/BR0112856A/pt not_active IP Right Cessation
- 2001-07-26 JP JP2002515877A patent/JP2004505070A/ja active Pending
- 2001-07-26 CZ CZ2003297A patent/CZ2003297A3/cs unknown
- 2001-07-26 CN CN01813601A patent/CN1444573A/zh active Pending
- 2001-07-26 PL PL01365183A patent/PL365183A1/xx unknown
- 2001-07-26 AP APAP/P/2003/002720A patent/AP2003002720A0/en unknown
- 2001-07-26 OA OA1200300018A patent/OA12346A/en unknown
- 2001-07-26 IL IL15364501A patent/IL153645A0/xx unknown
- 2001-07-26 HU HU0302966A patent/HUP0302966A2/hu unknown
- 2001-07-26 AU AU2001278508A patent/AU2001278508A1/en not_active Abandoned
- 2001-07-26 KR KR10-2003-7001409A patent/KR20030059084A/ko not_active Application Discontinuation
- 2001-07-26 SK SK114-2003A patent/SK1142003A3/sk not_active Application Discontinuation
- 2001-07-26 MX MXPA03000923A patent/MXPA03000923A/es not_active Application Discontinuation
- 2001-07-26 EP EP01956562A patent/EP1305304A1/en not_active Withdrawn
- 2001-07-26 WO PCT/EP2001/008637 patent/WO2002010146A1/en not_active Application Discontinuation
- 2001-07-26 CA CA002417638A patent/CA2417638A1/en not_active Abandoned
- 2001-07-26 EA EA200300064A patent/EA200300064A1/ru unknown
-
2003
- 2003-01-24 MA MA27012A patent/MA25829A1/fr unknown
- 2003-01-30 BG BG107510A patent/BG107510A/bg unknown
- 2003-01-30 NO NO20030471A patent/NO20030471L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO20030471L (no) | 2003-03-28 |
CA2417638A1 (en) | 2002-02-07 |
KR20030059084A (ko) | 2003-07-07 |
IL153645A0 (en) | 2003-07-06 |
CZ2003297A3 (cs) | 2003-05-14 |
OA12346A (en) | 2004-04-13 |
MA25829A1 (fr) | 2003-07-01 |
MXPA03000923A (es) | 2003-06-09 |
AU2001278508A1 (en) | 2002-02-13 |
AP2003002720A0 (en) | 2003-06-30 |
NO20030471D0 (no) | 2003-01-30 |
WO2002010146A1 (en) | 2002-02-07 |
BR0112856A (pt) | 2003-07-01 |
CN1444573A (zh) | 2003-09-24 |
JP2004505070A (ja) | 2004-02-19 |
EA200300064A1 (ru) | 2003-06-26 |
HUP0302966A2 (hu) | 2003-12-29 |
PL365183A1 (en) | 2004-12-27 |
SK1142003A3 (en) | 2003-06-03 |
EP1305304A1 (en) | 2003-05-02 |
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