BG106907A - Nogo рецептор - медиирана блокада на аксоналния растеж - Google Patents
Nogo рецептор - медиирана блокада на аксоналния растеж Download PDFInfo
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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| US20736600P | 2000-05-26 | 2000-05-26 | |
| US23637800P | 2000-09-29 | 2000-09-29 | |
| PCT/US2001/001041 WO2001051520A2 (en) | 2000-01-12 | 2001-01-12 | Nogo receptor-mediated blockade of axonal growth |
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| BG106907A true BG106907A (bg) | 2003-05-30 |
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| BG106907A BG106907A (bg) | 2000-01-12 | 2002-07-05 | Nogo рецептор - медиирана блокада на аксоналния растеж |
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| US7371836B2 (en) | 1998-03-27 | 2008-05-13 | Genentech, Inc. | PRO526 nucleic acids |
| US7723488B2 (en) | 1998-03-27 | 2010-05-25 | Genentech, Inc. | Monoclonal antibodies to secreted and transmembrane polypeptides |
| US20020072493A1 (en) * | 1998-05-19 | 2002-06-13 | Yeda Research And Development Co. Ltd. | Activated T cells, nervous system-specific antigens and their uses |
| JP2002518010A (ja) | 1998-06-16 | 2002-06-25 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | ９４個のヒト分泌タンパク質 |
| US7034132B2 (en) | 2001-06-04 | 2006-04-25 | Anderson David W | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| US7119165B2 (en) * | 2000-01-12 | 2006-10-10 | Yale University | Nogo receptor-mediated blockade of axonal growth |
| NZ520065A (en) * | 2000-01-12 | 2006-02-24 | Univ Yale | Nogo receptor-mediated blockade of axonal growth |
| ATE458815T1 (de) | 2000-10-06 | 2010-03-15 | Univ Yale | Homologe des nogo rezeptors |
| GB0101313D0 (en) * | 2001-01-18 | 2001-02-28 | Glaxo Group Ltd | Assay |
| GB0101312D0 (en) | 2001-01-18 | 2001-02-28 | Glaxo Group Ltd | Assay |
| EP1386004A4 (en) * | 2001-04-05 | 2005-02-16 | Ribozyme Pharm Inc | MODULATION OF GENE EXPRESSION ASSOCIATED WITH INFLAMMATORY PROLIFERATION AND GROWTH OF NEURITIES BY METHODS INVOLVING NUCLEIC ACID |
| EP1423427A2 (en) * | 2001-08-27 | 2004-06-02 | Novartis AG | Nogo receptor homologues and their use |
| US7309485B2 (en) * | 2001-12-03 | 2007-12-18 | Children's Medical Center Corporation | Reducing myelin-mediated inhibition of axon regeneration |
| FR2841261B1 (fr) * | 2002-06-25 | 2004-08-27 | Univ Pasteur | Compositions et methodes pour detecter les pathologies affectant la transmission neuromusculaire |
| SI1534736T1 (sl) * | 2002-08-10 | 2010-10-29 | Univ Yale | Antagonisti Nogo receptorja |
| DE60332842D1 (de) * | 2002-08-10 | 2010-07-15 | Univ Yale | Antagonisten des nogo-rezeptors |
| GB0228832D0 (en) * | 2002-12-10 | 2003-01-15 | Novartis Ag | Organic compound |
| DE60332481D1 (de) * | 2002-12-06 | 2010-06-17 | Zhi Cheng Xiao | Peptide und deren verwendung in der behandlung von krankheiten des zentralen nervensystems |
| US7842666B2 (en) * | 2002-12-20 | 2010-11-30 | Research Foundation Of City University Of New York | Inhibitors of myelin-associated glycoprotein (MAG) activity for regulating neural growth and regeneration |
| RS54160B1 (sr) | 2003-03-19 | 2015-12-31 | Biogen Idec Ma Inc. | Protein koji se vezuje za nogo receptor |
| EP1623036A4 (en) * | 2003-04-04 | 2007-06-20 | Univ Rochester | IDENTIFICATION OF NEW NOGO RECEPTORS AND ASSOCIATED METHODS |
| EA009643B1 (ru) * | 2003-04-16 | 2008-02-28 | Йейл Юниверсити | Лечение состояний, включающих амилоидные бляшки |
| US7867976B2 (en) * | 2003-05-15 | 2011-01-11 | The Board Of Trustees Of The Leland Stanford Junior University | Nogo epitopic fragments for modulating immune response |
| US7959914B2 (en) | 2003-05-16 | 2011-06-14 | Acorda Therapeutics, Inc. | Methods of reducing extravasation of inflammatory cells |
| EP3514238B1 (en) * | 2003-05-16 | 2021-05-05 | Acorda Therapeutics, Inc. | Proteoglycan degrading mutants for treatment of cns |
| GB0321997D0 (en) * | 2003-09-19 | 2003-10-22 | Novartis Ag | Organic compound |
| US8912144B2 (en) * | 2003-12-16 | 2014-12-16 | Children's Medical Center Corporation | Method for treating stroke via administration of NEP1-40 and inosine |
| WO2005059515A2 (en) * | 2003-12-16 | 2005-06-30 | Children's Medical Center Corporation | Method for treating neurological disorders |
| WO2006002437A2 (en) | 2004-06-24 | 2006-01-05 | Biogen Idec Ma Inc. | Treatment of conditions involving demyelination |
| EP1789070B1 (en) | 2004-08-03 | 2012-10-24 | Biogen Idec MA Inc. | Taj in neuronal function |
| EP1805209A4 (en) * | 2004-10-01 | 2008-04-02 | Univ Yale | NOGO-A POLYPEPTIDE FRAGMENTS, VARIANT OF NOGO RECEPTOR-1 POLYPEPTIDES AND USE |
| SG157418A1 (en) * | 2004-12-01 | 2009-12-29 | Univ Singapore | Nogo a protein fragments as neuronal network- interacting peptides |
| WO2007008732A2 (en) * | 2005-07-07 | 2007-01-18 | Yale University | Compositions and methods for suppressing axonal growth inhibition |
| PT1904104E (pt) | 2005-07-08 | 2013-11-21 | Biogen Idec Inc | Anticorpos sp35 e suas utilizações |
| CA2623635C (en) | 2005-09-26 | 2013-04-02 | Acorda Therapeutics, Inc. | Compositions and methods of using chondroitinase abci mutants |
| BRPI0707276B1 (pt) | 2006-01-27 | 2021-08-31 | Biogen Ma Inc | Polipeptídeo de fusão antagonista de receptor nogo |
| JP2009538282A (ja) * | 2006-05-15 | 2009-11-05 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 乏突起膠細胞の生存を促進させるためのＮｏｇｏ受容体−１（ＮｇＲ１）アンタゴニストの使用 |
| JP2009544703A (ja) | 2006-07-24 | 2009-12-17 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | Ｓｐ３５またはＴｒｋＡアンタゴニストの投与により髄鞘形成、ニューロンの生存および希乏突起膠細胞の分化を促進するための方法 |
| CN101969999B (zh) * | 2006-11-21 | 2017-03-22 | 雅培制药有限公司 | 抗nogo‑66受体(ngr)的中和单克隆抗体及其用途 |
| EP2276500A4 (en) | 2008-03-13 | 2015-03-04 | Univ Yale | REACTIVATION OF AXONE GROWTH AND CHRONIC MEDALLIONAL LESIONAL HEALING |
| CL2009001155A1 (es) * | 2008-05-13 | 2010-06-04 | Genentech Inc | Anticuerpo anti-pirb/lilrb aislado; polinucleotido que lo codifica; vector; celula huesped; metodo de obtencion; composicion farmaceutica que lo comprende; kit; y su uso para tratar enfermedades neurodegenerativas. |
| EP2982695B1 (en) | 2008-07-09 | 2019-04-03 | Biogen MA Inc. | Compositions comprising antibodies to lingo or fragments thereof |
| NZ702178A (en) | 2012-05-14 | 2017-01-27 | Biogen Ma Inc | Lingo-2 antagonists for treatment of conditions involving motor neurons |
| CN104935294B (zh) * | 2014-03-20 | 2018-07-20 | 晶宏半导体股份有限公司 | 振荡器 |
| JP2018504400A (ja) | 2015-01-08 | 2018-02-15 | バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． | Ｌｉｎｇｏ‐１拮抗薬及び脱髄障害の治療のための使用 |
| CN109354605B (zh) * | 2015-07-17 | 2021-02-05 | 暨南大学 | 一种Nogo-A受体结合肽及其衍生物与应用 |
| CN113527462B (zh) * | 2020-04-22 | 2023-05-23 | 北京大学 | 一种具有镇痛作用的小分子肽及其特异性抗体 |
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