BG104568A - Фармацевтичен състав, съдържащ сибутрамин и орлистат - Google Patents

Фармацевтичен състав, съдържащ сибутрамин и орлистат Download PDF

Info

Publication number
BG104568A
BG104568A BG104568A BG10456800A BG104568A BG 104568 A BG104568 A BG 104568A BG 104568 A BG104568 A BG 104568A BG 10456800 A BG10456800 A BG 10456800A BG 104568 A BG104568 A BG 104568A
Authority
BG
Bulgaria
Prior art keywords
compound
formula
enantiomers
orlistat
pharmaceutically acceptable
Prior art date
Application number
BG104568A
Other languages
Bulgarian (bg)
English (en)
Inventor
David J. Heal
Helen C. Jackson
Original Assignee
Knoll Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Aktiengesellschaft filed Critical Knoll Aktiengesellschaft
Publication of BG104568A publication Critical patent/BG104568A/bg

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
BG104568A 1997-12-24 2000-06-28 Фармацевтичен състав, съдържащ сибутрамин и орлистат BG104568A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9727131.6A GB9727131D0 (en) 1997-12-24 1997-12-24 Therapeutic agents
PCT/EP1998/008249 WO1999033450A2 (en) 1997-12-24 1998-12-16 Pharmaceutical composition containing sibutramine and orlistat

Publications (1)

Publication Number Publication Date
BG104568A true BG104568A (bg) 2001-02-28

Family

ID=10824083

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104568A BG104568A (bg) 1997-12-24 2000-06-28 Фармацевтичен състав, съдържащ сибутрамин и орлистат

Country Status (26)

Country Link
US (1) US6403641B2 (ja)
EP (1) EP1039900B1 (ja)
JP (1) JP2001527036A (ja)
KR (1) KR20010033531A (ja)
CN (1) CN1134257C (ja)
AT (1) ATE268174T1 (ja)
AU (1) AU758181B2 (ja)
BG (1) BG104568A (ja)
BR (1) BR9814498A (ja)
CA (1) CA2315259A1 (ja)
CZ (1) CZ20002392A3 (ja)
DE (1) DE69824313T2 (ja)
DK (1) DK1039900T3 (ja)
ES (1) ES2222001T3 (ja)
GB (1) GB9727131D0 (ja)
HK (1) HK1034446A1 (ja)
HU (1) HUP0300615A3 (ja)
IL (1) IL136733A (ja)
NO (1) NO20003313L (ja)
NZ (1) NZ505686A (ja)
PL (1) PL342099A1 (ja)
PT (1) PT1039900E (ja)
SK (1) SK9492000A3 (ja)
TR (1) TR200001869T2 (ja)
UA (1) UA70310C2 (ja)
WO (1) WO1999033450A2 (ja)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6331571B1 (en) 1998-08-24 2001-12-18 Sepracor, Inc. Methods of treating and preventing attention deficit disorders
US6974838B2 (en) 1998-08-24 2005-12-13 Sepracor Inc. Methods of treating or preventing pain using sibutramine metabolites
US6476078B2 (en) 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US6339106B1 (en) 1999-08-11 2002-01-15 Sepracor, Inc. Methods and compositions for the treatment and prevention of sexual dysfunction
GB9914744D0 (en) * 1999-06-24 1999-08-25 Knoll Ag Therapeutic agents
US6399826B1 (en) 1999-08-11 2002-06-04 Sepracor Inc. Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
PL204443B1 (pl) 2000-07-28 2010-01-29 Hoffmann La Roche Kompozycja farmaceutyczna zawierająca inhibitor lipazy, sposób wytwarzania kompozycji farmaceutycznej, zestaw do leczenia otyłości, zastosowanie kompozycji farmaceutycznej oraz zastosowanie orlistatu i substancji wiążącej kwasy żółciowe
US6610887B2 (en) 2001-04-13 2003-08-26 Sepracor Inc. Methods of preparing didesmethylsibutramine and other sibutramine derivatives
US6730319B2 (en) * 2001-06-06 2004-05-04 Hoffmann-La Roche Inc. Pharmaceutical compositions having depressed melting points
CA2530634A1 (en) * 2003-06-12 2004-12-23 Menachem Rubinstein Methods of treating obesity and related disorders using tellurium and selenium compounds
US20050131074A1 (en) * 2003-08-04 2005-06-16 Beckman Kristen M. Methods for treating metabolic syndrome
EP1744772B1 (en) 2004-05-10 2017-08-16 University of Copenhagen Flaxseeds for body weight management
EP2625968A1 (en) 2007-09-12 2013-08-14 Københavns Universitet Composition and methods for increasing the suppression of hunger and reducing the digestibility of non-fat energy satiety
US20090214682A1 (en) * 2008-02-22 2009-08-27 Heuer Marvin A Composition and methods for weight loss in a subject
JP5738011B2 (ja) * 2011-03-04 2015-06-17 株式会社ブリヂストン 二次電池の非水電解液用添加剤、二次電池用非水電解液及び非水電解液二次電池
CN102872062A (zh) * 2011-07-13 2013-01-16 鲁南制药集团股份有限公司 一种治疗或预防肥胖症以及代谢综合症的药物组合物
JP2013147488A (ja) * 2011-12-21 2013-08-01 Taisho Pharmaceutical Co Ltd 固形製剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52768B1 (en) 1981-04-06 1988-02-17 Boots Co Ltd 1-arylcyclobutylalkylamine compounds useful as therapeutic agents
CA1247547A (en) * 1983-06-22 1988-12-28 Paul Hadvary Leucine derivatives
CA1328881C (en) 1984-12-21 1994-04-26 Pierre Barbier Process for the manufacture of oxetanones
GB8531071D0 (en) 1985-12-17 1986-01-29 Boots Co Plc Therapeutic compound
GB8704777D0 (en) 1987-02-28 1987-04-01 Boots Co Plc Medical treatment
JP2675573B2 (ja) 1988-03-31 1997-11-12 科研製薬株式会社 脳機能改善剤
IE61928B1 (en) 1988-11-29 1994-11-30 Boots Co Plc Treatment of obesity
CA2128044C (en) 1993-08-05 2007-02-20 Klaus-Dieter Bremer Pharmaceutical compositions comprising a glucosidase and/or amylase inhibitor, and a lipase inhibitor
US5459164A (en) 1994-02-03 1995-10-17 Boots Pharmaceuticals, Inc. Medical treatment

Also Published As

Publication number Publication date
NO20003313L (no) 2000-08-11
WO1999033450A2 (en) 1999-07-08
ES2222001T3 (es) 2005-01-16
IL136733A (en) 2004-08-31
CZ20002392A3 (cs) 2002-01-16
HUP0300615A3 (en) 2005-04-28
CN1284872A (zh) 2001-02-21
JP2001527036A (ja) 2001-12-25
PT1039900E (pt) 2004-09-30
WO1999033450A3 (en) 1999-09-02
US6403641B2 (en) 2002-06-11
AU758181B2 (en) 2003-03-20
CA2315259A1 (en) 1999-07-08
PL342099A1 (en) 2001-05-21
US20020010160A1 (en) 2002-01-24
AU2273899A (en) 1999-07-19
NZ505686A (en) 2002-07-26
EP1039900A2 (en) 2000-10-04
BR9814498A (pt) 2000-10-10
UA70310C2 (uk) 2004-10-15
CN1134257C (zh) 2004-01-14
HK1034446A1 (en) 2001-10-26
SK9492000A3 (en) 2001-07-10
GB9727131D0 (en) 1998-02-25
NO20003313D0 (no) 2000-06-23
IL136733A0 (en) 2001-06-14
EP1039900B1 (en) 2004-06-02
TR200001869T2 (tr) 2000-10-23
ATE268174T1 (de) 2004-06-15
KR20010033531A (ko) 2001-04-25
HUP0300615A2 (hu) 2003-07-28
DK1039900T3 (da) 2004-10-04
DE69824313D1 (de) 2004-07-08
DE69824313T2 (de) 2005-08-25

Similar Documents

Publication Publication Date Title
BG104568A (bg) Фармацевтичен състав, съдържащ сибутрамин и орлистат
US6376552B1 (en) Treatment of gallstones
RU2229289C2 (ru) Фармацевтическая композиция, содержащая сибутрамин и орлистат
WO2000056318A1 (en) Treatment of neuropathic pain or fibromyalgia
SK18822001A3 (sk) Terapeutické činidlá
US6232347B1 (en) Treatment of osteoarthritis
US20040198837A1 (en) Treatment of neuropathic pain or fibromyalgia
RU2234917C2 (ru) Терапевтические средства
WO2000056306A1 (en) Treatment of osteoarthritis
US20030008897A1 (en) Method of controlling weight gain associated with therapeutic drugs
EP1162964A1 (en) Treatment of pulmonary hypertension
MXPA00006201A (en) Pharmaceutical composition containing sibutramine and orlistat
WO2000056316A1 (en) Treatment of gallstones