BG104527A - Лекарствени формиы съдържащи разтворен пароксетин - Google Patents

Лекарствени формиы съдържащи разтворен пароксетин

Info

Publication number
BG104527A
BG104527A BG104527A BG10452700A BG104527A BG 104527 A BG104527 A BG 104527A BG 104527 A BG104527 A BG 104527A BG 10452700 A BG10452700 A BG 10452700A BG 104527 A BG104527 A BG 104527A
Authority
BG
Bulgaria
Prior art keywords
paroxetine
solid
formulations
solutions
dissolved
Prior art date
Application number
BG104527A
Other languages
English (en)
Inventor
Ahmad Ghazawi
Graham LEONARD
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of BG104527A publication Critical patent/BG104527A/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Изобретението се отнася до лекарствени форми на пароксетин, в които той е в разтвор в твърд, полутвърд или течен носител. Разтворите се използват за напълване на капсули или твърди разтвори се оформят в твърди дозирани форми, например таблети или пилюли. Изобретението включва и нови течни форми, в които се използва средство за солубилизиране на пароксетин в масла и/или липиди, както и методи за получаване на други пароксетинови форми, превръщащисе в хемихидрат, с използването на безводни или хидрофобни носители или пълнители.
BG104527A 1997-11-21 2000-06-13 Лекарствени формиы съдържащи разтворен пароксетин BG104527A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9724544.3A GB9724544D0 (en) 1997-11-21 1997-11-21 Novel Formulation
PCT/GB1998/003471 WO1999026625A1 (en) 1997-11-21 1998-11-18 Formulations comprising dissolved paroxetine

Publications (1)

Publication Number Publication Date
BG104527A true BG104527A (bg) 2001-04-30

Family

ID=10822374

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104527A BG104527A (bg) 1997-11-21 2000-06-13 Лекарствени формиы съдържащи разтворен пароксетин

Country Status (24)

Country Link
EP (1) EP1033986A1 (bg)
JP (1) JP2001523718A (bg)
KR (1) KR20010032320A (bg)
CN (1) CN1279608A (bg)
AP (1) AP2000001821A0 (bg)
AR (1) AR015485A1 (bg)
AU (1) AU1168099A (bg)
BG (1) BG104527A (bg)
BR (1) BR9814220A (bg)
CO (1) CO4970832A1 (bg)
DZ (1) DZ2658A1 (bg)
EA (1) EA200000552A1 (bg)
GB (1) GB9724544D0 (bg)
HU (1) HUP0100580A3 (bg)
IL (1) IL136106A0 (bg)
MA (1) MA24704A1 (bg)
NO (1) NO20002590L (bg)
OA (1) OA11385A (bg)
PE (1) PE20000381A1 (bg)
PL (1) PL340555A1 (bg)
SK (1) SK7342000A3 (bg)
TR (1) TR200001423T2 (bg)
WO (1) WO1999026625A1 (bg)
ZA (1) ZA9810637B (bg)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9810180D0 (en) * 1998-05-13 1998-07-08 Smithkline Beecham Plc Novel formulation
EP1161241B1 (de) * 1999-03-12 2005-12-07 Aesica Pharmaceuticals Ltd. Stabile pharmazeutische anwendungsform für paroxetin-anhydrat
ATE248165T1 (de) 1999-07-01 2003-09-15 Italfarmaco Spa Komplexe von paroxetin mit cyclodextrin oder cyclodextrin derivaten
DE19930454A1 (de) * 1999-07-02 2001-01-04 Knoll Ag Feste Paroxetin enthaltende Zubereitungen
US6720003B2 (en) 2001-02-16 2004-04-13 Andrx Corporation Serotonin reuptake inhibitor formulations
DE60222803T2 (de) * 2001-12-21 2008-07-17 Supernus Pharmaceuticals, Inc. Orale kapselformulierung mit verbesserter physikalischer stabilität
SE0200475D0 (sv) * 2002-02-15 2002-02-15 Ltp Lipid Technologies Provide Oral farmaceutisk beredning
WO2006119779A2 (en) * 2005-05-10 2006-11-16 Lifecycle Pharma A/S A pharmaceutical composition comprising an aldosterone antagonist in form of solid solution
WO2011071194A1 (ko) * 2009-12-08 2011-06-16 주식회사 일화 20-O-β-D-글루코피라노실-20(S)-프로토파낙사디올을 포함하는 고체분산체
GB201020032D0 (en) * 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
CN103961333B (zh) * 2014-05-07 2020-02-21 浙江华海药业股份有限公司 甲磺酸帕罗西汀胶囊及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2216934A1 (en) * 1995-04-03 1996-10-10 Abbott Laboratories Homogeneous mixtures of low temperature-melting drugs and additives for controlled release
KR20000070151A (ko) * 1997-01-15 2000-11-25 피터 기딩스 파록세틴 조성물

Also Published As

Publication number Publication date
DZ2658A1 (fr) 2003-03-22
HUP0100580A3 (en) 2002-05-28
EP1033986A1 (en) 2000-09-13
ZA9810637B (en) 2000-05-22
CN1279608A (zh) 2001-01-10
WO1999026625A1 (en) 1999-06-03
KR20010032320A (ko) 2001-04-16
AR015485A1 (es) 2001-05-02
TR200001423T2 (tr) 2000-10-23
NO20002590L (no) 2000-07-19
EA200000552A1 (ru) 2000-10-30
IL136106A0 (en) 2001-05-20
AP2000001821A0 (en) 2000-06-30
MA24704A1 (fr) 1999-07-01
CO4970832A1 (es) 2000-11-07
SK7342000A3 (en) 2000-12-11
JP2001523718A (ja) 2001-11-27
NO20002590D0 (no) 2000-05-19
AU1168099A (en) 1999-06-15
BR9814220A (pt) 2001-12-26
HUP0100580A2 (hu) 2002-04-29
GB9724544D0 (en) 1998-01-21
OA11385A (en) 2004-01-27
PL340555A1 (en) 2001-02-12
PE20000381A1 (es) 2000-05-07

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