BR9814220A - Formulações compreendendo paroxetinadissolvida - Google Patents

Formulações compreendendo paroxetinadissolvida

Info

Publication number
BR9814220A
BR9814220A BR9814220-8A BR9814220A BR9814220A BR 9814220 A BR9814220 A BR 9814220A BR 9814220 A BR9814220 A BR 9814220A BR 9814220 A BR9814220 A BR 9814220A
Authority
BR
Brazil
Prior art keywords
formulations
solid
paroxetine
solutions
forms
Prior art date
Application number
BR9814220-8A
Other languages
English (en)
Inventor
Ahmad Ghazawi
Graham Stanley Leonard
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of BR9814220A publication Critical patent/BR9814220A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"FORMULAçõES COMPREENDENDO PAROXETINADISSOLVIDA". A presente invenção refere-se a formulaçõesfarmacêuticas em que a paroxetina está em solução em umveículo sólido, semi-sólido ou líquido. As soluções são usadas paraencher cápsulas, ou soluções sólidas de auto-suporte sãomoldadas em formas de dosagem sólidas tais como tabletes epelotas. Também são mostradas formulações liquidas em que umagente solubilizante é usado para solubilizar paroxetina em óleose/ou lipídios, e métodos para evitar que outras formas deparoxetina se convertam em hemi-hidrato de veículos ouexcipientes anidros ou hidrofóbicos.
BR9814220-8A 1997-11-21 1998-11-18 Formulações compreendendo paroxetinadissolvida BR9814220A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9724544.3A GB9724544D0 (en) 1997-11-21 1997-11-21 Novel Formulation
PCT/GB1998/003471 WO1999026625A1 (en) 1997-11-21 1998-11-18 Formulations comprising dissolved paroxetine

Publications (1)

Publication Number Publication Date
BR9814220A true BR9814220A (pt) 2001-12-26

Family

ID=10822374

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9814220-8A BR9814220A (pt) 1997-11-21 1998-11-18 Formulações compreendendo paroxetinadissolvida

Country Status (24)

Country Link
EP (1) EP1033986A1 (pt)
JP (1) JP2001523718A (pt)
KR (1) KR20010032320A (pt)
CN (1) CN1279608A (pt)
AP (1) AP2000001821A0 (pt)
AR (1) AR015485A1 (pt)
AU (1) AU1168099A (pt)
BG (1) BG104527A (pt)
BR (1) BR9814220A (pt)
CO (1) CO4970832A1 (pt)
DZ (1) DZ2658A1 (pt)
EA (1) EA200000552A1 (pt)
GB (1) GB9724544D0 (pt)
HU (1) HUP0100580A3 (pt)
IL (1) IL136106A0 (pt)
MA (1) MA24704A1 (pt)
NO (1) NO20002590L (pt)
OA (1) OA11385A (pt)
PE (1) PE20000381A1 (pt)
PL (1) PL340555A1 (pt)
SK (1) SK7342000A3 (pt)
TR (1) TR200001423T2 (pt)
WO (1) WO1999026625A1 (pt)
ZA (1) ZA9810637B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9810180D0 (en) * 1998-05-13 1998-07-08 Smithkline Beecham Plc Novel formulation
JP4854115B2 (ja) 1999-03-12 2012-01-18 エイシカ ファーマシューティカルス リミテッド 無水パロキセチン用安定製剤形
PT1109806E (pt) 1999-07-01 2004-02-27 Italfarmaco Spa Complexos de paroxetina com ciclodextrinas ou derivados de ciclodextrinas
DE19930454A1 (de) * 1999-07-02 2001-01-04 Knoll Ag Feste Paroxetin enthaltende Zubereitungen
US6720003B2 (en) 2001-02-16 2004-04-13 Andrx Corporation Serotonin reuptake inhibitor formulations
ATE374602T1 (de) * 2001-12-21 2007-10-15 Supernus Pharmaceuticals Inc Orale kapselformulierung mit verbesserter physikalischer stabilität
SE0200475D0 (sv) * 2002-02-15 2002-02-15 Ltp Lipid Technologies Provide Oral farmaceutisk beredning
WO2006119779A2 (en) * 2005-05-10 2006-11-16 Lifecycle Pharma A/S A pharmaceutical composition comprising an aldosterone antagonist in form of solid solution
WO2011071194A1 (ko) * 2009-12-08 2011-06-16 주식회사 일화 20-O-β-D-글루코피라노실-20(S)-프로토파낙사디올을 포함하는 고체분산체
GB201020032D0 (en) * 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
CN103961333B (zh) * 2014-05-07 2020-02-21 浙江华海药业股份有限公司 甲磺酸帕罗西汀胶囊及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2216934A1 (en) * 1995-04-03 1996-10-10 Abbott Laboratories Homogeneous mixtures of low temperature-melting drugs and additives for controlled release
AP9901604A0 (en) * 1997-01-15 1999-09-30 Smithkline Beecham Plc Paroxetine compositions.

Also Published As

Publication number Publication date
JP2001523718A (ja) 2001-11-27
GB9724544D0 (en) 1998-01-21
CO4970832A1 (es) 2000-11-07
TR200001423T2 (tr) 2000-10-23
NO20002590D0 (no) 2000-05-19
PE20000381A1 (es) 2000-05-07
HUP0100580A3 (en) 2002-05-28
IL136106A0 (en) 2001-05-20
EA200000552A1 (ru) 2000-10-30
CN1279608A (zh) 2001-01-10
AP2000001821A0 (en) 2000-06-30
HUP0100580A2 (hu) 2002-04-29
SK7342000A3 (en) 2000-12-11
ZA9810637B (en) 2000-05-22
OA11385A (en) 2004-01-27
DZ2658A1 (fr) 2003-03-22
PL340555A1 (en) 2001-02-12
AR015485A1 (es) 2001-05-02
EP1033986A1 (en) 2000-09-13
KR20010032320A (ko) 2001-04-16
NO20002590L (no) 2000-07-19
MA24704A1 (fr) 1999-07-01
AU1168099A (en) 1999-06-15
WO1999026625A1 (en) 1999-06-03
BG104527A (en) 2001-04-30

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]