BG103914A - Фармацевтичен състав с продължително освобождаване и неговото използаве - Google Patents

Фармацевтичен състав с продължително освобождаване и неговото използаве

Info

Publication number
BG103914A
BG103914A BG103914A BG10391499A BG103914A BG 103914 A BG103914 A BG 103914A BG 103914 A BG103914 A BG 103914A BG 10391499 A BG10391499 A BG 10391499A BG 103914 A BG103914 A BG 103914A
Authority
BG
Bulgaria
Prior art keywords
delayed gels
maintained separation
separation
maintained
gels
Prior art date
Application number
BG103914A
Other languages
English (en)
Other versions
BG64860B1 (bg
Inventor
Merrill Goldenberg
Alice Beekman
Jian Gu
Original Assignee
Amgen Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc. filed Critical Amgen Inc.
Publication of BG103914A publication Critical patent/BG103914A/bg
Publication of BG64860B1 publication Critical patent/BG64860B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Изобретението се отнася до състави с поддържано отделяне на забавени гелове и методи за получаването им.
BG103914A 1997-05-16 1999-11-23 Фармацевтичен състав с продължително освобождаване и неговото използване BG64860B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85797397A 1997-05-16 1997-05-16
US91290297A 1997-08-15 1997-08-15

Publications (2)

Publication Number Publication Date
BG103914A true BG103914A (bg) 2000-07-31
BG64860B1 BG64860B1 (bg) 2006-07-31

Family

ID=27127437

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103914A BG64860B1 (bg) 1997-05-16 1999-11-23 Фармацевтичен състав с продължително освобождаване и неговото използване

Country Status (18)

Country Link
EP (1) EP0981374B1 (bg)
JP (1) JP2001525826A (bg)
KR (1) KR20010012374A (bg)
AU (1) AU7491898A (bg)
BG (1) BG64860B1 (bg)
BR (1) BR9809117A (bg)
CA (1) CA2289196C (bg)
CZ (1) CZ299180B6 (bg)
DE (1) DE69838750T2 (bg)
EA (1) EA199901013A1 (bg)
ES (1) ES2294814T3 (bg)
HU (1) HUP0003393A3 (bg)
IL (1) IL132814A0 (bg)
NO (1) NO995591L (bg)
PL (1) PL199565B1 (bg)
SK (1) SK286437B6 (bg)
WO (1) WO1998051348A2 (bg)
YU (1) YU58599A (bg)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003200609B2 (en) * 1998-05-18 2006-02-23 Amgen Inc. Biodegradable sustained-release alginate gels
US6432449B1 (en) * 1998-05-18 2002-08-13 Amgen Inc. Biodegradable sustained-release alginate gels
JP2000256216A (ja) * 1999-03-04 2000-09-19 Meiji Milk Prod Co Ltd ゲル組成物
US7582311B1 (en) 1999-10-15 2009-09-01 Genentech, Inc. Injection vehicle for polymer-based formulations
US7651703B2 (en) 1999-10-15 2010-01-26 Genentech, Inc. Injection vehicle for polymer-based formulations
US20030021848A1 (en) * 1999-11-29 2003-01-30 Johnson Matthew S. Sustained percutaneous delivery of a biologically active substance
FR2823119B1 (fr) * 2001-04-05 2004-02-20 Seppic Sa Adjuvant d'immunite contenant un cation metallique complexe et vaccin le contenant
BR0315663A (pt) * 2002-10-25 2005-08-30 Pfizer Prod Inc Formulações de depósito de agentes ativos de aril-heterocìclicos na forma de uma suspensão
US8329207B2 (en) * 2005-05-23 2012-12-11 Natural Alternatives International, Inc. Compositions and methods for the sustained release of beta-alanine
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
JP5107585B2 (ja) * 2007-01-29 2012-12-26 株式会社 メドレックス 低温充填ゼリー組成物とその製造方法
EP1985286A1 (en) * 2007-04-24 2008-10-29 Biocompatibles UK Limited Microspheres for treatment of brain tumours
BR112013009205A2 (pt) 2010-10-15 2016-07-26 Iscience Interventional Corp dispositivo para colocação na esclera de um olho, método para acessar o espaço supracoroidal de um olho, para acessar o espaço subretinal de um olho e para colocar um orifício dentro de um trato escleral em um olho.
AU2013342275B2 (en) 2012-11-08 2017-11-09 Clearside Biomedical, Inc. Methods and devices for the treatment of ocular diseases in human subjects
CA3121759C (en) 2013-05-03 2024-01-02 Clearside Biomedical, Inc. Apparatus and methods for ocular injection
US10010447B2 (en) 2013-12-18 2018-07-03 Novartis Ag Systems and methods for subretinal delivery of therapeutic agents
RU2710491C2 (ru) 2014-06-20 2019-12-26 Клиасайд Байомедикал, Инк. Устройство для инъекции лекарственного средства в глазную ткань и способ инъекции лекарственного средства в глазную ткань
WO2017139375A1 (en) 2016-02-10 2017-08-17 Clearside Biomedical, Inc. Ocular injection kit, packaging, and methods of use
CA3062845A1 (en) 2016-05-02 2017-11-09 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
CA3072847A1 (en) 2016-08-12 2018-02-15 Clearside Biomedical, Inc. Devices and methods for adjusting the insertion depth of a needle for medicament delivery
CN112367841B (zh) * 2018-06-04 2023-06-09 斯博姆维透公司 用于制备水凝胶的功能化试剂盒
WO2020096281A1 (ko) * 2018-11-06 2020-05-14 국립암센터 알긴산 기반의 주입형 수화젤 시스템
US20220257637A1 (en) * 2019-10-01 2022-08-18 Brillian Pharma Inc. Methods for treating or preventing obesity and body weight management
CN114533653B (zh) * 2020-11-26 2023-12-22 上海凯茂生物医药有限公司 一种人促红素杂合Fc融合蛋白相变型制剂及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5416979B2 (bg) * 1972-01-08 1979-06-26
US4241099A (en) * 1979-02-26 1980-12-23 Tiemstra Peter J Pectin formulations, products and methods having delayed-action acidulants
US4690682A (en) * 1983-04-15 1987-09-01 Damon Biotech, Inc. Sustained release
US4789516A (en) * 1983-04-15 1988-12-06 Damon Biotech, Inc Production of sustained released system
US4744933A (en) * 1984-02-15 1988-05-17 Massachusetts Institute Of Technology Process for encapsulation and encapsulated active material system
CA1215922A (en) * 1984-05-25 1986-12-30 Connaught Laboratories Limited Microencapsulation of living tissue and cells
JPS645460A (en) * 1987-06-29 1989-01-10 Sanei Kagaku Kogyo Kk Production of delaying gelatinous material
JPH0794583B2 (ja) * 1989-12-15 1995-10-11 株式会社大塚製薬工場 高含水高分子ゲル
IT1245383B (it) * 1991-03-28 1994-09-20 Eniricerche Spa Composizione acquosa gelificabile avente tempo di gelificazione ritardato
US5711968A (en) * 1994-07-25 1998-01-27 Alkermes Controlled Therapeutics, Inc. Composition and method for the controlled release of metal cation-stabilized interferon
KR960006730B1 (ko) * 1993-02-11 1996-05-23 재단법인한국화학연구소 에멀젼 네트웍(emulsion network)을 이용한 약물의 피부 전달체계
GB9708773D0 (en) * 1997-04-30 1997-06-25 Reckitt & Colmann Prod Ltd Organic compositions

Also Published As

Publication number Publication date
HUP0003393A2 (hu) 2001-02-28
ES2294814T3 (es) 2008-04-01
DE69838750D1 (de) 2008-01-03
KR20010012374A (ko) 2001-02-15
BR9809117A (pt) 2000-08-01
BG64860B1 (bg) 2006-07-31
DE69838750T2 (de) 2008-10-30
SK154399A3 (en) 2000-07-11
CA2289196C (en) 2007-08-07
WO1998051348A3 (en) 1999-02-18
EA199901013A1 (ru) 2000-06-26
NO995591D0 (no) 1999-11-15
CZ396399A3 (cs) 2000-04-12
CZ299180B6 (cs) 2008-05-14
PL336887A1 (en) 2000-07-17
AU7491898A (en) 1998-12-08
PL199565B1 (pl) 2008-10-31
IL132814A0 (en) 2001-03-19
CA2289196A1 (en) 1998-11-19
YU58599A (sh) 2000-12-28
JP2001525826A (ja) 2001-12-11
HUP0003393A3 (en) 2001-03-28
EP0981374A2 (en) 2000-03-01
SK286437B6 (sk) 2008-10-07
WO1998051348A2 (en) 1998-11-19
NO995591L (no) 1999-11-15
EP0981374B1 (en) 2007-11-21

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