BG102228A - Medicamentous form with controlled release of slightly soluble medicamentous substances - Google Patents

Medicamentous form with controlled release of slightly soluble medicamentous substances

Info

Publication number
BG102228A
BG102228A BG102228A BG10222898A BG102228A BG 102228 A BG102228 A BG 102228A BG 102228 A BG102228 A BG 102228A BG 10222898 A BG10222898 A BG 10222898A BG 102228 A BG102228 A BG 102228A
Authority
BG
Bulgaria
Prior art keywords
medicamentous
controlled release
substances
slightly soluble
oraladministration
Prior art date
Application number
BG102228A
Other languages
Bulgarian (bg)
English (en)
Inventor
Maurice Clancy
Kenneth Cumming
Micheal MYERS
Original Assignee
Elan Corporation, Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Corporation, Plc filed Critical Elan Corporation, Plc
Publication of BG102228A publication Critical patent/BG102228A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG102228A 1995-07-03 1998-02-02 Medicamentous form with controlled release of slightly soluble medicamentous substances BG102228A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IE950492A IE80467B1 (en) 1995-07-03 1995-07-03 Controlled release formulations for poorly soluble drugs
US89795P 1995-07-06 1995-07-06
PCT/IE1996/000039 WO1997002017A1 (en) 1995-07-03 1996-07-01 Controlled release formulations for poorly soluble drugs

Publications (1)

Publication Number Publication Date
BG102228A true BG102228A (en) 1998-10-30

Family

ID=26319833

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102228A BG102228A (en) 1995-07-03 1998-02-02 Medicamentous form with controlled release of slightly soluble medicamentous substances

Country Status (20)

Country Link
EP (1) EP0836475B1 (xx)
JP (1) JPH11508587A (xx)
KR (1) KR19990028693A (xx)
AT (1) ATE208192T1 (xx)
AU (1) AU700654B2 (xx)
BG (1) BG102228A (xx)
BR (1) BR9609663A (xx)
CA (1) CA2226008A1 (xx)
CZ (1) CZ413497A3 (xx)
DE (1) DE69616795T2 (xx)
HU (1) HUP9900231A2 (xx)
IE (1) IE80467B1 (xx)
IL (1) IL122663A0 (xx)
NO (1) NO975872L (xx)
NZ (1) NZ311145A (xx)
PL (1) PL324402A1 (xx)
SK (1) SK175997A3 (xx)
TW (1) TW426528B (xx)
WO (1) WO1997002017A1 (xx)
ZA (1) ZA965609B (xx)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283029B1 (it) * 1996-05-17 1998-04-03 Resa Farma Composizioni farmaceutiche a base di diclofenac
BE1009856A5 (fr) 1995-07-14 1997-10-07 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule.
KR19990067264A (ko) * 1995-12-01 1999-08-16 디르크 반테 서방형 시사프라이드
AU7888298A (en) * 1997-01-03 1998-07-31 Elan Corporation, Plc Sustained release cisapride minitablet formulation
DE19710009A1 (de) * 1997-03-12 1998-09-24 Knoll Ag Mehrphasige wirkstoffhaltige Zubereitungsformen
US6312724B1 (en) 1997-04-04 2001-11-06 Isa Odidi Sustained release pharmaceutical matrix tablet of pharmaceutically acceptable salts of diclofenac and process for preparation thereof
NZ328751A (en) * 1997-09-16 1999-01-28 Bernard Charles Sherman Solid medicament containing an anionic surfactant and cyclosporin
US6013280A (en) * 1997-10-07 2000-01-11 Fuisz Technologies Ltd. Immediate release dosage forms containing microspheres
BR9806303A (pt) * 1997-10-07 2000-03-14 Fuisz Technologies Ltd Sistema de distrituição de droga termoformado, e, unidade de dosagem
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
IE980115A1 (en) * 1998-02-16 2000-02-09 Biovail Internat Ltd Solubilizing delivery systems and method of manufacture
US6787157B1 (en) 1998-03-10 2004-09-07 Abbott Laboratories Multiphase active ingredient-containing formulations
WO1999063971A1 (en) * 1998-06-11 1999-12-16 Em Industries, Inc. Micro-osmotic controlled drug delivery systems
TW407058B (en) * 1998-07-17 2000-10-01 Dev Center Biotechnology Oral cisapride dosage forms with an extended duration
IE981008A1 (en) * 1998-12-02 2000-06-14 Fuisz Internat Ltd Microparticles Containing Water Insoluble Active Agents
ES2310164T3 (es) * 1999-02-10 2009-01-01 Pfizer Products Inc. Dispositivo de liberacion controlada por la matriz.
US6706283B1 (en) 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
EP1064938A1 (en) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Pharmaceutical dosage forms for controlled release producing at least a timed pulse
SE9902742D0 (sv) * 1999-07-20 1999-07-20 Astra Ab New pharmaceutical formultion
KR100379299B1 (ko) * 2000-01-15 2003-04-10 주식회사 중외제약 펠로디핀의 가용화 방법 및 방출제어형 제제
MXPA03009971A (es) * 2001-05-03 2004-02-12 Hoffmann La Roche FORMA DE DOSIFICACIoN FARMACEUTICA DE MESILATO DE NELFINAVIR AMORFO.
AR033711A1 (es) * 2001-05-09 2004-01-07 Novartis Ag Composiciones farmaceuticas
TWI252111B (en) * 2001-12-14 2006-04-01 Solvay Pharm Gmbh Matrix film tablet with controlled release of a natural mixture of conjugated estrogens
US20050232995A1 (en) 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
KR20040011248A (ko) * 2002-07-30 2004-02-05 환인제약 주식회사 암로디핀의 고체분산체와 그 제조방법 및 그를 포함하는약학적 조성물
AU2002350719A1 (en) * 2002-11-29 2004-06-23 Janssen Pharmaceutica N.V. Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base
US20050163839A1 (en) * 2003-01-29 2005-07-28 Sun Pharmaceutical Industries Limited Oral controlled release pharmaceutical composition containing metaxalone as active agent
JP2006518380A (ja) 2003-01-31 2006-08-10 スミスクライン・ビーチャム・コーポレイション 固体分散体組成物
WO2004084870A1 (en) * 2003-03-28 2004-10-07 Sigmoid Biotechnologies Limited Solid oral dosage form containing seamless microcapsules
JP2007511518A (ja) * 2003-11-13 2007-05-10 アルザ・コーポレーシヨン 溶融ブレンド分散体
WO2005065653A1 (en) * 2003-12-19 2005-07-21 E.I. Du Pont De Nemours And Company Intimate coating of ibuprofen with poloxamers to enhance aqueous dissolution
BRPI0418330A (pt) 2003-12-31 2007-05-02 Pfizer Prod Inc composições sólidas de drogas de solubilidade baixa e poloxámeros
KR100598326B1 (ko) 2004-04-10 2006-07-10 한미약품 주식회사 ＨＭＧ-ＣｏＡ 환원효소 억제제의 경구투여용 서방형 제제및 이의 제조방법
CA2633266C (en) * 2005-12-16 2011-08-02 Hanmi Pharm. Co., Ltd. Solid dispersion comprising an active ingredient having a low melting point and tablet for oral administration comprising same
JP5546860B2 (ja) 2006-08-16 2014-07-09 ノバルティス アーゲー 高結晶性治療化合物の固体分散体を製造するための方法
WO2008120131A2 (en) * 2007-03-30 2008-10-09 Wockhardt Research Centre Pharmaceutical compositions of diclofenac and misoprostol
CA2683407C (en) 2007-04-04 2016-09-20 Sigmoid Pharma Limited Pharmaceutical cyclosporin compositions
JP2010527285A (ja) 2007-04-26 2010-08-12 シグモイド・ファーマ・リミテッド 複数のミニカプセルの製造
CN106420667A (zh) 2009-04-24 2017-02-22 伊休蒂卡有限公司 双氯芬酸的新剂型
WO2010133609A2 (en) 2009-05-18 2010-11-25 Sigmoid Pharma Limited Composition comprising oil drops
CN102573802A (zh) 2009-08-12 2012-07-11 希格默伊德药业有限公司 包含聚合物基质和油相的免疫调节组合物
FR2967577B1 (fr) 2010-11-18 2013-07-12 Advicenne Pharma Composition pharmaceutique comprenant du sel de bicarbonate, et son utilisation comme medicament
FR2967576B1 (fr) * 2010-11-18 2013-07-12 Advicenne Pharma Composition pharmaceutique comprenant du sel precurseur du cycle de krebs, en particulier du sel de citrate, et son utilisation comme medicament
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
DE102012105512A1 (de) * 2012-06-25 2014-04-24 Hennig Arzneimittel Gmbh & Co. Kg Arzneiform zur verlängerten Freisetzung von Wirkstoffen
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
CN102784128B (zh) * 2012-07-31 2015-01-07 北京协和药厂 一种非洛地平缓释制剂及其制备方法
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
US9526734B2 (en) 2014-06-09 2016-12-27 Iceutica Pty Ltd. Formulation of meloxicam
BR112017009510A2 (pt) 2014-11-07 2017-12-19 Sigmoid Pharma Ltd composições compreendendo ciclosporina
EP3793527A1 (en) * 2018-05-14 2021-03-24 Capsugel Belgium NV Solid dosage forms with high active agent loading

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE76292T1 (de) * 1987-11-25 1992-06-15 American Cyanamid Co System fuer die verzoegerte (kontrollierte) freisetzung von substituierten dihydropyridincalciumantagonisten.

Also Published As

Publication number Publication date
KR19990028693A (ko) 1999-04-15
TW426528B (en) 2001-03-21
EP0836475B1 (en) 2001-11-07
ZA965609B (en) 1997-01-27
NZ311145A (en) 1999-06-29
CA2226008A1 (en) 1997-01-23
DE69616795D1 (de) 2001-12-13
WO1997002017A1 (en) 1997-01-23
JPH11508587A (ja) 1999-07-27
BR9609663A (pt) 1999-05-18
NO975872L (no) 1998-03-03
NO975872D0 (no) 1997-12-12
ATE208192T1 (de) 2001-11-15
IL122663A0 (en) 1998-08-16
PL324402A1 (en) 1998-05-25
AU700654B2 (en) 1999-01-14
CZ413497A3 (cs) 1998-04-15
DE69616795T2 (de) 2002-08-08
AU6239496A (en) 1997-02-05
SK175997A3 (en) 1998-06-03
EP0836475A1 (en) 1998-04-22
HUP9900231A2 (hu) 1999-06-28
IE80467B1 (en) 1998-07-29
MX9710413A (es) 1998-07-31

Similar Documents

Publication Publication Date Title
BG102228A (en) Medicamentous form with controlled release of slightly soluble medicamentous substances
CA2232450A1 (en) Oral pharmaceutical composition containing antimicrobial actives and sustained release pantoprazole
CA2209714A1 (en) A controlled release formulation for poorly soluble basic drugs
MX9701465A (es) Formulacion de acetaminofeno, de liberacion sostenida.
UA29563C2 (uk) Мікрокапсула для тривалого вивільнення фізіологічно активного пептиду
CA2231195A1 (en) Sustained release matrix for high-dose insoluble drugs
CA2258095A1 (en) Tetrahydrolipstatin containing compositions
AU1351788A (en) Slow-release pharmaceutical agent
AU7315496A (en) Delivery of biologically active polypeptides
CA2229279A1 (en) Nutritional and/or dietary composition and method of using the same
EP1275381A4 (en) SOLID COATED PREPARATIONS WITH TEMPERATURE RELEASE FOR ORAL ADMINISTRATION
HK1046244A1 (en) Controlled release and taste masking oral pharmaceutical compositions.
AU5673399A (en) Compositions and methods for treating intracellular infections
GR3021936T3 (en) Pharmaceutical composition comprising a medicament and a water-swellable polymer
NZ324674A (en) Rapid release tablet comprising tolfenamic acid, alginic acid and a superdisintegrant
NZ510360A (en) Fish gelatinous composition for use as an ingredient in tablets
WO2003061557A3 (en) Levothyroxine pharmaceutical compositions, methods of making and methods of administration
CA2273272A1 (en) Immediate release drug delivery forms
AU2503900A (en) Sulfated phosphatidylinositols, their preparation and use
IT1317871B1 (it) Sistemi terapeutici per forme farmaceutiche orali di principi attiviaventi sfavorevoli caratteristiche organolettiche.