BG101163A - 8-fluoro-anthracyclines, processes for their preparation and pharmaceutical compositions containing them - Google Patents
8-fluoro-anthracyclines, processes for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- BG101163A BG101163A BG101163A BG10116397A BG101163A BG 101163 A BG101163 A BG 101163A BG 101163 A BG101163 A BG 101163A BG 10116397 A BG10116397 A BG 10116397A BG 101163 A BG101163 A BG 101163A
- Authority
- BG
- Bulgaria
- Prior art keywords
- anthracyclines
- fluoro
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
- C07C50/36—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having four or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/38—Quinones containing —CHO or non—quinoid keto groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI941696A IT1271689B (it) | 1994-08-04 | 1994-08-04 | 8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono |
PCT/EP1995/003061 WO1996004292A1 (fr) | 1994-08-04 | 1995-08-01 | 8-fluoro-anthracyclines, procedes de preparation et compositions pharmaceutique les contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
BG101163A true BG101163A (en) | 1997-09-30 |
Family
ID=11369446
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG101163A Pending BG101163A (en) | 1994-08-04 | 1997-01-22 | 8-fluoro-anthracyclines, processes for their preparation and pharmaceutical compositions containing them |
Country Status (25)
Country | Link |
---|---|
US (1) | US5814608A (fr) |
EP (1) | EP0776328B1 (fr) |
JP (1) | JPH10503509A (fr) |
AT (1) | ATE172980T1 (fr) |
AU (1) | AU700929B2 (fr) |
BG (1) | BG101163A (fr) |
BR (1) | BR9508518A (fr) |
CA (1) | CA2196752A1 (fr) |
CZ (1) | CZ28097A3 (fr) |
DE (1) | DE69505828T2 (fr) |
DK (1) | DK0776328T3 (fr) |
ES (1) | ES2126923T3 (fr) |
FI (1) | FI970455A (fr) |
HR (1) | HRP950436A2 (fr) |
HU (1) | HUT76339A (fr) |
IL (1) | IL114791A0 (fr) |
IT (1) | IT1271689B (fr) |
NO (1) | NO305561B1 (fr) |
NZ (1) | NZ291426A (fr) |
PL (1) | PL319630A1 (fr) |
RU (1) | RU2146261C1 (fr) |
SK (1) | SK13797A3 (fr) |
TJ (1) | TJ245B (fr) |
WO (1) | WO1996004292A1 (fr) |
ZA (1) | ZA956480B (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999058543A1 (fr) * | 1998-05-13 | 1999-11-18 | Instytut Farmaceutyczny | Nouveaux derives n-alkyloxycarbonyliques de monosaccharides l-acosamine et l-daunosamine |
RU2450013C2 (ru) * | 2005-12-13 | 2012-05-10 | Солюкс Корпорейшен | Способ получения 4-деметилдаунорубицина |
US8802830B2 (en) * | 2005-12-20 | 2014-08-12 | Solux Corporation | Synthesis of epirubicin from 13-dihydrodaunorubicine |
US8357785B2 (en) * | 2008-01-08 | 2013-01-22 | Solux Corporation | Method of aralkylation of 4′-hydroxyl group of anthracylins |
RU2642068C1 (ru) * | 2017-04-26 | 2018-01-24 | Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) | N-пиперонильные производные даунорубицина, обладающие антипролиферативными свойствами |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MA21995A1 (fr) * | 1989-11-13 | 1991-07-01 | Menarini Farma Ind | Nouvelles fluoronaphthacenediones,leurs derives glycozyles et leurs procedes de fabrication . |
IT1241927B (it) * | 1990-05-14 | 1994-02-01 | Menarini Farma Ind | 3'-deamino-4'-deossi-4'-amino-8-fluoroantra- cicline processi per la loro preparazione e composizioni farmaceutiche che le contengono |
AU653348B2 (en) * | 1990-06-11 | 1994-09-29 | Belleau, Pierrette | Heterocyclic anthracyclinone and anthracycline analogs |
IT1262565B (it) * | 1993-09-30 | 1996-07-04 | Menarini Farma Ind | Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono. |
-
1994
- 1994-08-04 IT ITMI941696A patent/IT1271689B/it active IP Right Grant
-
1995
- 1995-07-31 IL IL11479195A patent/IL114791A0/xx unknown
- 1995-08-01 RU RU97103523A patent/RU2146261C1/ru active
- 1995-08-01 NZ NZ291426A patent/NZ291426A/en unknown
- 1995-08-01 EP EP95929043A patent/EP0776328B1/fr not_active Expired - Lifetime
- 1995-08-01 CA CA002196752A patent/CA2196752A1/fr not_active Abandoned
- 1995-08-01 AT AT95929043T patent/ATE172980T1/de active
- 1995-08-01 PL PL95319630A patent/PL319630A1/xx unknown
- 1995-08-01 WO PCT/EP1995/003061 patent/WO1996004292A1/fr not_active Application Discontinuation
- 1995-08-01 SK SK137-97A patent/SK13797A3/sk unknown
- 1995-08-01 CZ CZ97280A patent/CZ28097A3/cs unknown
- 1995-08-01 ES ES95929043T patent/ES2126923T3/es not_active Expired - Lifetime
- 1995-08-01 DE DE69505828T patent/DE69505828T2/de not_active Expired - Fee Related
- 1995-08-01 JP JP8506204A patent/JPH10503509A/ja active Pending
- 1995-08-01 BR BR9508518A patent/BR9508518A/pt not_active Application Discontinuation
- 1995-08-01 US US08/776,627 patent/US5814608A/en not_active Expired - Fee Related
- 1995-08-01 AU AU32553/95A patent/AU700929B2/en not_active Ceased
- 1995-08-01 HU HU9700341A patent/HUT76339A/hu unknown
- 1995-08-01 TJ TJ97000445A patent/TJ245B/xx unknown
- 1995-08-01 DK DK95929043T patent/DK0776328T3/da active
- 1995-08-03 ZA ZA956480A patent/ZA956480B/xx unknown
- 1995-08-03 HR HRMI94A001696A patent/HRP950436A2/hr not_active Application Discontinuation
-
1997
- 1997-01-08 NO NO970059A patent/NO305561B1/no unknown
- 1997-01-22 BG BG101163A patent/BG101163A/xx active Pending
- 1997-02-03 FI FI970455A patent/FI970455A/fi unknown
Also Published As
Publication number | Publication date |
---|---|
IT1271689B (it) | 1997-06-04 |
EP0776328B1 (fr) | 1998-11-04 |
ES2126923T3 (es) | 1999-04-01 |
AU700929B2 (en) | 1999-01-14 |
WO1996004292A1 (fr) | 1996-02-15 |
NO970059D0 (no) | 1997-01-08 |
NO970059L (no) | 1997-01-08 |
FI970455A0 (fi) | 1997-02-03 |
EP0776328A1 (fr) | 1997-06-04 |
DE69505828D1 (de) | 1998-12-10 |
RU2146261C1 (ru) | 2000-03-10 |
ZA956480B (en) | 1996-03-14 |
CZ28097A3 (en) | 1997-08-13 |
SK13797A3 (en) | 1997-07-09 |
DK0776328T3 (da) | 1999-07-19 |
JPH10503509A (ja) | 1998-03-31 |
HUT76339A (en) | 1997-08-28 |
IL114791A0 (en) | 1995-11-27 |
PL319630A1 (en) | 1997-08-18 |
BR9508518A (pt) | 1997-12-23 |
AU3255395A (en) | 1996-03-04 |
ITMI941696A1 (it) | 1996-02-04 |
FI970455A (fi) | 1997-02-03 |
DE69505828T2 (de) | 1999-05-20 |
NO305561B1 (no) | 1999-06-21 |
NZ291426A (en) | 1998-05-27 |
US5814608A (en) | 1998-09-29 |
CA2196752A1 (fr) | 1996-02-15 |
ATE172980T1 (de) | 1998-11-15 |
ITMI941696A0 (it) | 1994-08-04 |
HRP950436A2 (en) | 1997-10-31 |
TJ245B (en) | 2001-08-06 |
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