BG101163A - 8-fluoro-anthracyclines, processes for their preparation and pharmaceutical compositions containing them - Google Patents

8-fluoro-anthracyclines, processes for their preparation and pharmaceutical compositions containing them

Info

Publication number
BG101163A
BG101163A BG101163A BG10116397A BG101163A BG 101163 A BG101163 A BG 101163A BG 101163 A BG101163 A BG 101163A BG 10116397 A BG10116397 A BG 10116397A BG 101163 A BG101163 A BG 101163A
Authority
BG
Bulgaria
Prior art keywords
anthracyclines
fluoro
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
BG101163A
Other languages
Bulgarian (bg)
English (en)
Inventor
Fabio Animati
Federico Arcamone
Giuseppe Giannini
Paolo Lombardi
Edith Monteagudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol-Myers Squibb SpA
Menarini A Industrie Farmaceutiche Riunite
Original Assignee
Bristol-Myers Squibb SpA
Menarini A Industrie Farmaceutiche Riunite
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb SpA, Menarini A Industrie Farmaceutiche Riunite filed Critical Bristol-Myers Squibb SpA
Publication of BG101163A publication Critical patent/BG101163A/xx
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/36—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having four or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/38—Quinones containing —CHO or non—quinoid keto groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BG101163A 1994-08-04 1997-01-22 8-fluoro-anthracyclines, processes for their preparation and pharmaceutical compositions containing them Pending BG101163A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI941696A IT1271689B (it) 1994-08-04 1994-08-04 8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono
PCT/EP1995/003061 WO1996004292A1 (fr) 1994-08-04 1995-08-01 8-fluoro-anthracyclines, procedes de preparation et compositions pharmaceutique les contenant

Publications (1)

Publication Number Publication Date
BG101163A true BG101163A (en) 1997-09-30

Family

ID=11369446

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101163A Pending BG101163A (en) 1994-08-04 1997-01-22 8-fluoro-anthracyclines, processes for their preparation and pharmaceutical compositions containing them

Country Status (25)

Country Link
US (1) US5814608A (fr)
EP (1) EP0776328B1 (fr)
JP (1) JPH10503509A (fr)
AT (1) ATE172980T1 (fr)
AU (1) AU700929B2 (fr)
BG (1) BG101163A (fr)
BR (1) BR9508518A (fr)
CA (1) CA2196752A1 (fr)
CZ (1) CZ28097A3 (fr)
DE (1) DE69505828T2 (fr)
DK (1) DK0776328T3 (fr)
ES (1) ES2126923T3 (fr)
FI (1) FI970455A (fr)
HR (1) HRP950436A2 (fr)
HU (1) HUT76339A (fr)
IL (1) IL114791A0 (fr)
IT (1) IT1271689B (fr)
NO (1) NO305561B1 (fr)
NZ (1) NZ291426A (fr)
PL (1) PL319630A1 (fr)
RU (1) RU2146261C1 (fr)
SK (1) SK13797A3 (fr)
TJ (1) TJ245B (fr)
WO (1) WO1996004292A1 (fr)
ZA (1) ZA956480B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058543A1 (fr) * 1998-05-13 1999-11-18 Instytut Farmaceutyczny Nouveaux derives n-alkyloxycarbonyliques de monosaccharides l-acosamine et l-daunosamine
RU2450013C2 (ru) * 2005-12-13 2012-05-10 Солюкс Корпорейшен Способ получения 4-деметилдаунорубицина
US8802830B2 (en) * 2005-12-20 2014-08-12 Solux Corporation Synthesis of epirubicin from 13-dihydrodaunorubicine
US8357785B2 (en) * 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
RU2642068C1 (ru) * 2017-04-26 2018-01-24 Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) N-пиперонильные производные даунорубицина, обладающие антипролиферативными свойствами

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA21995A1 (fr) * 1989-11-13 1991-07-01 Menarini Farma Ind Nouvelles fluoronaphthacenediones,leurs derives glycozyles et leurs procedes de fabrication .
IT1241927B (it) * 1990-05-14 1994-02-01 Menarini Farma Ind 3'-deamino-4'-deossi-4'-amino-8-fluoroantra- cicline processi per la loro preparazione e composizioni farmaceutiche che le contengono
AU653348B2 (en) * 1990-06-11 1994-09-29 Belleau, Pierrette Heterocyclic anthracyclinone and anthracycline analogs
IT1262565B (it) * 1993-09-30 1996-07-04 Menarini Farma Ind Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono.

Also Published As

Publication number Publication date
IT1271689B (it) 1997-06-04
EP0776328B1 (fr) 1998-11-04
ES2126923T3 (es) 1999-04-01
AU700929B2 (en) 1999-01-14
WO1996004292A1 (fr) 1996-02-15
NO970059D0 (no) 1997-01-08
NO970059L (no) 1997-01-08
FI970455A0 (fi) 1997-02-03
EP0776328A1 (fr) 1997-06-04
DE69505828D1 (de) 1998-12-10
RU2146261C1 (ru) 2000-03-10
ZA956480B (en) 1996-03-14
CZ28097A3 (en) 1997-08-13
SK13797A3 (en) 1997-07-09
DK0776328T3 (da) 1999-07-19
JPH10503509A (ja) 1998-03-31
HUT76339A (en) 1997-08-28
IL114791A0 (en) 1995-11-27
PL319630A1 (en) 1997-08-18
BR9508518A (pt) 1997-12-23
AU3255395A (en) 1996-03-04
ITMI941696A1 (it) 1996-02-04
FI970455A (fi) 1997-02-03
DE69505828T2 (de) 1999-05-20
NO305561B1 (no) 1999-06-21
NZ291426A (en) 1998-05-27
US5814608A (en) 1998-09-29
CA2196752A1 (fr) 1996-02-15
ATE172980T1 (de) 1998-11-15
ITMI941696A0 (it) 1994-08-04
HRP950436A2 (en) 1997-10-31
TJ245B (en) 2001-08-06

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