BE903755A - Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments. - Google Patents

Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments.

Info

Publication number
BE903755A
BE903755A BE1/011392A BE1011392A BE903755A BE 903755 A BE903755 A BE 903755A BE 1/011392 A BE1/011392 A BE 1/011392A BE 1011392 A BE1011392 A BE 1011392A BE 903755 A BE903755 A BE 903755A
Authority
BE
Belgium
Prior art keywords
medicaments
novel
preparation
dihydropyridine derivatives
dihydropyridine
Prior art date
Application number
BE1/011392A
Other languages
English (en)
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of BE903755A publication Critical patent/BE903755A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Nouveaux dérivés de la 1,4-dihydropyridine, de formule I dans laquelle X, R1 et R2 signifient des radicaux organiques. Ces composés peuvent etre utilisés comme médicaments, notamment comme antagonistes du calcium.
BE1/011392A 1984-12-10 1985-12-02 Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments. BE903755A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3444965 1984-12-10

Publications (1)

Publication Number Publication Date
BE903755A true BE903755A (fr) 1986-06-02

Family

ID=6252356

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/011392A BE903755A (fr) 1984-12-10 1985-12-02 Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments.

Country Status (19)

Country Link
US (1) US4707482A (fr)
JP (1) JPS61140581A (fr)
AU (1) AU5100585A (fr)
BE (1) BE903755A (fr)
CH (1) CH665639A5 (fr)
DK (1) DK569185A (fr)
ES (1) ES8708226A1 (fr)
FI (1) FI854858A (fr)
FR (1) FR2574405A1 (fr)
GB (1) GB2168052A (fr)
GR (1) GR852954B (fr)
HU (1) HUT39179A (fr)
IT (1) IT1200155B (fr)
LU (1) LU86198A1 (fr)
NL (1) NL8503262A (fr)
PL (1) PL256694A1 (fr)
PT (1) PT81633B (fr)
SE (1) SE8505801L (fr)
ZA (1) ZA859444B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO874194L (no) * 1986-11-07 1988-05-09 Pfizer Ltd Fremgangsmaate ved fremstilling av dihydro-pyridinderivater
DK60493D0 (da) * 1993-05-26 1993-05-26 Novo Nordisk As Kemiske forbindelser, deres fremstilling og anvendelse

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4031104A (en) * 1972-04-18 1977-06-21 Bayer Aktiengesellschaft 1,4-Dihydropyridine carboxylic acid esters
US4466972A (en) * 1977-06-20 1984-08-21 Sandoz Ltd. Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them
UA8014A1 (uk) * 1977-06-20 1995-12-26 "Сандос АГ" Спосіб отримання похідних 1,4-дігідропірідину
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
FR2515652B1 (fr) * 1981-11-03 1985-10-25 Sandoz Sa Nouveaux derives de la 1,4-dihydropyridazine, leur preparation et medicaments contenant ces derives
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
EP0094159B1 (fr) * 1982-05-10 1990-03-14 Takeda Chemical Industries, Ltd. Dérivés de la dihydropyridine, leur préparation et leur application
DE3239273A1 (de) * 1982-10-23 1984-04-26 Bayer Ag, 5090 Leverkusen Tetrahydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
CH663616A5 (de) * 1983-06-21 1987-12-31 Sandoz Ag 1,4-dihydropyridin-derivate und sie enthaltende pharmazeutische zubereitungen.
DE3326384A1 (de) * 1983-07-22 1985-01-31 Bayer Ag, 5090 Leverkusen 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
US4603135A (en) * 1983-10-17 1986-07-29 Takeda Chemical Industries, Ltd. Substituted piperazinyl alkyl esters of 2-amino-4-aryl-1,4-dihydro-6-alkyl-3,5-pyridinedicarboxylates
DE3400765A1 (de) * 1984-01-12 1985-07-18 Bayer Ag, 5090 Leverkusen 1.4-dihydropyrazine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
ES549738A0 (es) 1987-10-01
FI854858A (fi) 1986-06-11
DK569185A (da) 1986-06-11
FI854858A0 (fi) 1985-12-09
IT8548898A0 (it) 1985-12-09
NL8503262A (nl) 1986-07-01
GB2168052A (en) 1986-06-11
US4707482A (en) 1987-11-17
PL256694A1 (en) 1987-09-21
GR852954B (fr) 1986-04-01
DK569185D0 (da) 1985-12-09
FR2574405A1 (fr) 1986-06-13
IT1200155B (it) 1989-01-05
SE8505801L (sv) 1986-06-11
ES8708226A1 (es) 1987-10-01
GB8530178D0 (en) 1986-01-15
AU5100585A (en) 1986-06-19
PT81633A (en) 1986-01-01
JPS61140581A (ja) 1986-06-27
HUT39179A (en) 1986-08-28
ZA859444B (en) 1987-07-29
SE8505801D0 (sv) 1985-12-09
PT81633B (en) 1987-10-13
CH665639A5 (de) 1988-05-31
LU86198A1 (fr) 1986-06-25

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SANDOZ S.A.

Effective date: 19881231