BE902213A - Composes de phenethanolamine. - Google Patents

Composes de phenethanolamine.

Info

Publication number
BE902213A
BE902213A BE0/214856A BE214856A BE902213A BE 902213 A BE902213 A BE 902213A BE 0/214856 A BE0/214856 A BE 0/214856A BE 214856 A BE214856 A BE 214856A BE 902213 A BE902213 A BE 902213A
Authority
BE
Belgium
Prior art keywords
compounds
derivatives
phenethanolamine compounds
phenethanolamine
adreno
Prior art date
Application number
BE0/214856A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848409909A external-priority patent/GB8409909D0/en
Priority claimed from GB848409910A external-priority patent/GB8409910D0/en
Priority claimed from GB848426206A external-priority patent/GB8426206D0/en
Priority claimed from GB848426197A external-priority patent/GB8426197D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of BE902213A publication Critical patent/BE902213A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/28—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/34—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups bound to carbon atoms of six-membered aromatic rings and etherified hydroxy groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/54—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Dérivés de la phénéthanol-amine de formule générale (I) dans laquelle Ar et Y et les substituants R1 et R2 possèdent les significations définies, ainsi que les sels et produits de solvatation physiologiquement acceptables de ces dérivés. Ces composés ont une action stimulante sélective sur les béta 2-adréno-récepteurs et conviennent notamment pour le traitement d'affections des voies aériennes.
BE0/214856A 1984-04-17 1985-04-17 Composes de phenethanolamine. BE902213A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB848409909A GB8409909D0 (en) 1984-04-17 1984-04-17 Chemical compounds
GB848409910A GB8409910D0 (en) 1984-04-17 1984-04-17 Chemical compounds
GB848426206A GB8426206D0 (en) 1984-10-17 1984-10-17 Chemical compounds
GB848426197A GB8426197D0 (en) 1984-10-17 1984-10-17 Chemical compounds

Publications (1)

Publication Number Publication Date
BE902213A true BE902213A (fr) 1985-10-17

Family

ID=27449546

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/214856A BE902213A (fr) 1984-04-17 1985-04-17 Composes de phenethanolamine.

Country Status (20)

Country Link
US (1) US4990505A (fr)
KR (1) KR850007422A (fr)
AU (1) AU582573B2 (fr)
BE (1) BE902213A (fr)
CH (1) CH667264A5 (fr)
DE (1) DE3513885A1 (fr)
DK (1) DK173785A (fr)
ES (2) ES8702880A1 (fr)
FI (1) FI851523L (fr)
FR (1) FR2562889B1 (fr)
GB (1) GB2159151B (fr)
GR (1) GR850936B (fr)
IL (1) IL74940A (fr)
IT (1) IT1181642B (fr)
LU (1) LU85856A1 (fr)
NL (1) NL8501124A (fr)
NO (1) NO162113C (fr)
NZ (1) NZ211822A (fr)
PT (1) PT80304B (fr)
SE (1) SE8501895L (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZW6584A1 (en) * 1983-04-18 1985-04-17 Glaxo Group Ltd Phenethanolamine derivatives
GB8426206D0 (en) * 1984-10-17 1984-11-21 Glaxo Holdings Ltd Chemical compounds
DE3571808D1 (en) * 1984-04-17 1989-08-31 Glaxo Group Ltd Ethanolamine compounds
DE3524990A1 (de) * 1984-07-13 1986-01-23 Glaxo Group Ltd., London Aminophenolverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen
JPS63290852A (ja) * 1987-02-10 1988-11-28 グラクソ、グループ、リミテッド 化合物
JPS6485964A (en) * 1987-03-12 1989-03-30 Glaxo Group Ltd Compound
GB8718938D0 (en) * 1987-08-11 1987-09-16 Glaxo Group Ltd Chemical compounds
GB8718940D0 (en) * 1987-08-11 1987-09-16 Glaxo Group Ltd Chemical compounds
PT88988B (pt) * 1987-11-13 1993-02-26 Glaxo Group Ltd Processo para a preparacao de derivados da fenetanolamina
EP0322164B1 (fr) * 1987-12-18 1993-09-22 Glaxo Group Limited Dérivés d'éthanolamine
ZA889405B (en) * 1987-12-18 1989-12-27 Glaxo Group Ltd Ethanolamine derivatives
NZ228329A (en) * 1988-03-18 1991-12-23 Mitsui Toatsu Chemicals Catechol derivatives and pharmaceutical compositions thereof
GB2230775A (en) * 1989-04-24 1990-10-31 Glaxo Group Ltd Phenethanolamine compounds
GB9215274D0 (en) * 1992-07-17 1992-09-02 Scras Derivatives of(phenylethyl-beta-ol)amine
GB0103630D0 (en) 2001-02-14 2001-03-28 Glaxo Group Ltd Chemical compounds
US7144908B2 (en) 2001-03-08 2006-12-05 Glaxo Group Limited Agonists of beta-adrenoceptors
DE60224172T2 (de) 2001-03-22 2008-12-04 Glaxo Group Ltd., Greenford Formanilid-derivative als beta2-adrenorezeptor-agonisten
CN1302007C (zh) 2001-04-30 2007-02-28 葛兰素集团有限公司 具有抗炎性的在17.α位上具有环酯基的雄甾烷的17.β.－硫代羧酸酯衍生物
KR100912324B1 (ko) 2001-09-14 2009-08-14 글락소 그룹 리미티드 호흡기 질환 치료용 펜에탄올아민 유도체
GB0204719D0 (en) * 2002-02-28 2002-04-17 Glaxo Group Ltd Medicinal compounds
ES2298511T3 (es) 2002-04-25 2008-05-16 Glaxo Group Limited Derivados de fenetanolamina.
GB0217225D0 (en) 2002-07-25 2002-09-04 Glaxo Group Ltd Medicinal compounds
GB0220730D0 (en) * 2002-09-06 2002-10-16 Glaxo Group Ltd Medicinal compounds
PL377122A1 (pl) 2002-10-28 2006-01-23 Glaxo Group Limited Pochodne fenetanoloaminy do leczenia chorób układu oddechowego
GB0225540D0 (en) * 2002-11-01 2002-12-11 Glaxo Group Ltd Medicinal compounds
DE10253220A1 (de) * 2002-11-15 2004-05-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Dihydroxy-Methyl-Phenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
GB0303396D0 (en) 2003-02-14 2003-03-19 Glaxo Group Ltd Medicinal compounds
BRPI0508927A (pt) * 2004-03-17 2007-08-14 Pfizer compostos úteis para o tratamento de doenças
EP1577291A1 (fr) * 2004-03-17 2005-09-21 Pfizer Limited Dérivés béta-2 agonistes de la phényléthanolamine

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1200886A (en) * 1966-09-23 1970-08-05 Allen & Hanburys Ltd Phenylaminoethanol derivatives
DE1543372A1 (de) * 1966-10-18 1971-04-01 Boehringer Sohn Ingelheim Verfahren zur Herstellung von o-substituierten 3,4-Dioxyphenylalkanolaminen
AT310146B (de) * 1971-04-26 1973-09-25 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen N,N'-Bis-(β-hydroxyaryläthyl)-diaminoalkanen und deren Säureadditionssalzen
US3879442A (en) * 1972-07-27 1975-04-22 Warner Lambert Co 5-hydroxy-{60 (substituted aminomethyl)-mu-xylene-{60 ,{60 -diols
HU168618B (fr) * 1974-06-17 1976-06-28
US4160036A (en) * 1975-07-29 1979-07-03 Allen & Hanburys Limited 4-Hydroxy-1,3-benzenedimethanol derivatives
US4154761A (en) * 1976-02-09 1979-05-15 Allen & Hanburys Limited Pharmacologically active compounds
JPS52113934A (en) * 1976-03-19 1977-09-24 Eisai Co Ltd Phenethylamine derivatives and bronchodilator containing the same
DE2965655D1 (en) * 1978-06-28 1983-07-21 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
EP0021636B1 (fr) * 1979-06-16 1982-12-01 Beecham Group Plc Amines secondaires, leur préparation et utilisation dans des compositions pharmaceutiques
US4379166A (en) * 1981-08-03 1983-04-05 Schering Corporation Arylmethoxy-, arylmethylthio-, heteroarylmethoxy-, and heteroarylmethylthio-alkylaminoalcohols
ZW6584A1 (en) * 1983-04-18 1985-04-17 Glaxo Group Ltd Phenethanolamine derivatives

Also Published As

Publication number Publication date
FR2562889B1 (fr) 1988-10-28
ES551507A0 (es) 1987-10-16
IT1181642B (it) 1987-09-30
IL74940A (en) 1988-06-30
FI851523A0 (fi) 1985-04-17
NO162113C (no) 1989-11-08
GR850936B (fr) 1985-11-25
NO162113B (no) 1989-07-31
SE8501895D0 (sv) 1985-04-17
US4990505A (en) 1991-02-05
KR850007422A (ko) 1985-12-04
FR2562889A1 (fr) 1985-10-18
DK173785D0 (da) 1985-04-17
NZ211822A (en) 1988-11-29
ES8800132A1 (es) 1987-10-16
AU582573B2 (en) 1989-04-06
GB2159151B (en) 1987-10-07
CH667264A5 (fr) 1988-09-30
IL74940A0 (en) 1985-08-30
DE3513885A1 (de) 1985-10-17
GB2159151A (en) 1985-11-27
SE8501895L (sv) 1985-10-18
FI851523L (fi) 1985-10-18
NL8501124A (nl) 1985-11-18
GB8509821D0 (en) 1985-05-22
DK173785A (da) 1985-10-18
PT80304A (en) 1985-05-01
ES8702880A1 (es) 1987-01-16
AU4134885A (en) 1985-10-24
ES542351A0 (es) 1987-01-16
NO851524L (no) 1985-10-18
IT8547971A0 (it) 1985-04-17
LU85856A1 (fr) 1986-06-11
IT8547971A1 (it) 1986-11-15
PT80304B (en) 1987-03-16

Similar Documents

Publication Publication Date Title
BE902213A (fr) Composes de phenethanolamine.
BE903334A (fr) Nouveaux derives naphtaleniques a action retinoique, leurs procedes de preparation et compositions medicamenteuse et cosmetique les contenant
BE901224A (fr) Nouveaux derives d'indole utiles comme medicaments et intermediaires et procedes pour leur preparation.
LU91587I2 (fr) Agomélatine et ses dérivés pharmaceutiquement acceptables (VALDOXAN)
FR2360587A1 (fr) Nouveaux derives d'amino-alcoyl-furannes utiles comme medicaments
FI880494A (fi) Nya 5-alkoxi-2,4-diaminoalkylbenzener samt dessa innehaollande haorfaergningsmedel.
BE901496R (fr) Nouveaux composes morpholino, leur procede de preparation et medicaments les contnant.
BE902876A (fr) Derives d'aminophenol
FR2369295A1 (fr) Derives
BE904641A (fr) 5-pyrimidine-carboxamides et traitement de la leucemie et des tumeurs avec ces derniers.
EP0144991A3 (en) Polymethosybenzyl piperazine derivatives, processes for their preparation and pharmaceutical compositions containing said derivatives
IL66518A (en) 2-(2'-hydroxy-3'-(1,1-dimethylpropylamino)-propoxy)beta-phenylpropiophenone,its acid addition salts,process for its preparation and pharmaceutical compositions
FR2443471A1 (fr) Derives du type thiazolidine de la progesterone utiles notamment comme precurseurs de medicaments antiacne et antiseborrhee
FR2395272A1 (fr) Nouveaux medicaments derives de l'acide amidinopenicillanique
ES2028838T3 (es) Procedimiento para la obtencion de nuevos derivados de 4,5-hidro-oxazoles.
IL66804A0 (en) 2-amino-1,2,3,4-tetrahydronaphthalene derivatives,their preparation and pharmaceutical compositions containing them
BE903376A (fr) Derives de la vitamine d et precurseurs de ceux-ci et compositions pharmaceutiques en contenant
BE905601A (fr) Derives de dichloroaniline.
FR2436134A1 (fr) Derives d'acide hydroxamique, leur procede de preparation et medicament les contenant
BE1003280A3 (fr) Derives oxo-isoindoliniques optiquement actifs.
FR2401922A1 (fr) Picolylamides d'acides 4-hydroxy-isophtaliques substitues, leur preparation et leurs utilisations therapeutiques
FR2358884A1 (fr) Compositions d'amino-alcools et leur procede de preparation et leur application notamment pour le traitement d'affections buccales
ZA842423B (en) Compounds with antiinflammatory activity,process for preparation thereof and pharmaceutical compositions therefrom
BE901489A (fr) Procede de traitement de maladies cardiaques.
BE904835A (fr) Nouveaux derives d'isoquinoleine, leur procede de preparation, leur application en therapeutique et produits intermediaires.

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: GLAXO GROUP LTD

Effective date: 19920430