BE883086A - Nouveaux derives d'acide 2-hydroxy-5-(1-hydroxy-2-piperazinylethyl)-benzoique, utiles notamment comme agents bloquants des recepteurs alpha - et beta-adrenergiques, et leur procede de preparation - Google Patents
Nouveaux derives d'acide 2-hydroxy-5-(1-hydroxy-2-piperazinylethyl)-benzoique, utiles notamment comme agents bloquants des recepteurs alpha - et beta-adrenergiques, et leur procede de preparationInfo
- Publication number
- BE883086A BE883086A BE0/200446A BE200446A BE883086A BE 883086 A BE883086 A BE 883086A BE 0/200446 A BE0/200446 A BE 0/200446A BE 200446 A BE200446 A BE 200446A BE 883086 A BE883086 A BE 883086A
- Authority
- BE
- Belgium
- Prior art keywords
- hydroxy
- piperazinylethyl
- beta
- alpha
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/036,244 US4255575A (en) | 1979-05-04 | 1979-05-04 | 2-Hydroxy-5-(1-hydroxy-2-piperazinylethyl)-benzoic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE883086A true BE883086A (fr) | 1980-09-01 |
Family
ID=21887503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE0/200446A BE883086A (fr) | 1979-05-04 | 1980-05-02 | Nouveaux derives d'acide 2-hydroxy-5-(1-hydroxy-2-piperazinylethyl)-benzoique, utiles notamment comme agents bloquants des recepteurs alpha - et beta-adrenergiques, et leur procede de preparation |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4255575A (fr) |
| JP (1) | JPS55147262A (fr) |
| AT (1) | AT376426B (fr) |
| AU (1) | AU531738B2 (fr) |
| BE (1) | BE883086A (fr) |
| CA (1) | CA1138457A (fr) |
| CH (1) | CH645368A5 (fr) |
| DE (1) | DE3014813A1 (fr) |
| DK (1) | DK159435C (fr) |
| ES (1) | ES8104995A1 (fr) |
| FR (1) | FR2455590A1 (fr) |
| GB (1) | GB2053897B (fr) |
| IE (1) | IE49549B1 (fr) |
| IL (1) | IL59596A (fr) |
| IT (1) | IT1143190B (fr) |
| NL (1) | NL8002071A (fr) |
| NO (1) | NO152698C (fr) |
| NZ (1) | NZ193107A (fr) |
| PH (1) | PH17089A (fr) |
| SE (1) | SE447109B (fr) |
| ZA (1) | ZA801453B (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3400168A1 (de) * | 1984-01-04 | 1985-07-11 | Bayer Ag, 5090 Leverkusen | 5-halogenalkyl-1,3,4-thiadiazol-2-yloxyacetamide |
| US4616017A (en) * | 1984-06-04 | 1986-10-07 | Merck & Co., Inc. | Aminohydroxypropoxy substituted aryl compounds |
| DE3505425A1 (de) * | 1985-02-16 | 1986-08-21 | Bayer Ag, 5090 Leverkusen | 5-chlor-1,3,4-thiadiazol-2-yloxy-acetamide |
| GB8603120D0 (en) * | 1986-02-07 | 1986-03-12 | Pfizer Ltd | Anti-dysrhythmia agents |
| GB8609630D0 (en) * | 1986-04-19 | 1986-05-21 | Pfizer Ltd | Anti-arrhythmia agents |
| US4956302A (en) * | 1987-09-11 | 1990-09-11 | Abbott Laboratories | Lateral flow chromatographic binding assay device |
| DE3812755A1 (de) * | 1988-04-16 | 1989-10-26 | Merck Patent Gmbh | Salicylsaeurederivate |
| KR100484386B1 (ko) * | 2000-10-04 | 2005-04-22 | 경동제약 주식회사 | 알킬2-[2,3,5-트리플루오로-4-(4-메틸-1-피페라지닐)]벤조일-3(ｓ)-(1-히드록시프로피-2-닐아미노)아크릴레이트의 제조방법 |
| US20080131954A1 (en) * | 2006-11-30 | 2008-06-05 | Canon U.S. Life Sciences, Inc. | Method of Separating Target DNA from Mixed DNA |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1317479A (en) * | 1970-11-10 | 1973-05-16 | Pfizer Ltd | 1-2-hydroxy-3-phenoxy or phenylthiopropyl-4-phenyl-piperazine derivatives |
| US4038279A (en) * | 1972-12-23 | 1977-07-26 | Boehringer Ingelheim Gmbh | N-aryl-n'-(phenyl-or phenoxy-alkyl)-piperazines and salts thereof |
| CA1113937A (fr) * | 1977-04-05 | 1981-12-08 | Frederic P. Hauck | Piperidinylpropanols substitues |
-
1979
- 1979-05-04 US US06/036,244 patent/US4255575A/en not_active Expired - Lifetime
-
1980
- 1980-03-10 IE IE481/80A patent/IE49549B1/en not_active IP Right Cessation
- 1980-03-12 ZA ZA00801453A patent/ZA801453B/xx unknown
- 1980-03-12 IL IL59596A patent/IL59596A/xx unknown
- 1980-03-12 NZ NZ193107A patent/NZ193107A/xx unknown
- 1980-03-21 PH PH23798A patent/PH17089A/en unknown
- 1980-03-26 IT IT48267/80A patent/IT1143190B/it active
- 1980-04-02 AU AU57076/80A patent/AU531738B2/en not_active Expired
- 1980-04-09 NL NL8002071A patent/NL8002071A/nl not_active Application Discontinuation
- 1980-04-17 DE DE19803014813 patent/DE3014813A1/de not_active Withdrawn
- 1980-04-17 ES ES490667A patent/ES8104995A1/es not_active Expired
- 1980-04-17 CA CA000350105A patent/CA1138457A/fr not_active Expired
- 1980-04-18 JP JP5054880A patent/JPS55147262A/ja active Granted
- 1980-04-22 CH CH309180A patent/CH645368A5/de not_active IP Right Cessation
- 1980-04-25 GB GB8013781A patent/GB2053897B/en not_active Expired
- 1980-04-29 SE SE8003244A patent/SE447109B/sv not_active IP Right Cessation
- 1980-04-30 AT AT0232580A patent/AT376426B/de not_active IP Right Cessation
- 1980-04-30 FR FR8009850A patent/FR2455590A1/fr active Granted
- 1980-05-01 DK DK193680A patent/DK159435C/da not_active IP Right Cessation
- 1980-05-02 BE BE0/200446A patent/BE883086A/fr not_active IP Right Cessation
- 1980-05-02 NO NO801297A patent/NO152698C/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH645368A5 (de) | 1984-09-28 |
| NO801297L (no) | 1980-11-05 |
| GB2053897A (en) | 1981-02-11 |
| NO152698B (no) | 1985-07-29 |
| FR2455590A1 (fr) | 1980-11-28 |
| GB2053897B (en) | 1982-10-20 |
| US4255575A (en) | 1981-03-10 |
| JPS55147262A (en) | 1980-11-17 |
| ZA801453B (en) | 1980-12-31 |
| AU5707680A (en) | 1980-11-06 |
| NL8002071A (nl) | 1980-11-06 |
| SE8003244L (sv) | 1980-11-05 |
| IE49549B1 (en) | 1985-10-30 |
| PH17089A (en) | 1984-05-29 |
| SE447109B (sv) | 1986-10-27 |
| IL59596A0 (en) | 1980-06-30 |
| ES490667A0 (es) | 1981-05-16 |
| DK159435B (da) | 1990-10-15 |
| DK159435C (da) | 1991-03-25 |
| ATA232580A (de) | 1984-04-15 |
| IT1143190B (it) | 1986-10-22 |
| AT376426B (de) | 1984-11-26 |
| DE3014813A1 (de) | 1980-11-13 |
| NZ193107A (en) | 1982-12-21 |
| FR2455590B1 (fr) | 1983-10-14 |
| DK193680A (da) | 1980-11-05 |
| ES8104995A1 (es) | 1981-05-16 |
| IE800481L (en) | 1980-11-04 |
| JPS6321666B2 (fr) | 1988-05-09 |
| CA1138457A (fr) | 1982-12-28 |
| AU531738B2 (en) | 1983-09-01 |
| IL59596A (en) | 1984-01-31 |
| IT8048267A0 (it) | 1980-03-26 |
| NO152698C (no) | 1985-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE20 | Patent expired |
Owner name: RICHARDSON-MERRELL INC. Effective date: 20000502 |