BE886438A - Procede de preparation du glucoside de l'acide mycophenolique, et glucoside ainsi obtenu - Google Patents

Procede de preparation du glucoside de l'acide mycophenolique, et glucoside ainsi obtenu

Info

Publication number
BE886438A
BE886438A BE1/10057A BE1010057A BE886438A BE 886438 A BE886438 A BE 886438A BE 1/10057 A BE1/10057 A BE 1/10057A BE 1010057 A BE1010057 A BE 1010057A BE 886438 A BE886438 A BE 886438A
Authority
BE
Belgium
Prior art keywords
glucoside
preparation
mycophenolic acid
mycophenolic
acid
Prior art date
Application number
BE1/10057A
Other languages
English (en)
Inventor
B J Abbott
J G Whitney
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BE886438A publication Critical patent/BE886438A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/04Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • C12R2001/485Streptomyces aureofaciens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • C12R2001/51Streptomyces candidus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces
    • Y10S435/892Streptomyces candidus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
BE1/10057A 1979-12-11 1980-12-02 Procede de preparation du glucoside de l'acide mycophenolique, et glucoside ainsi obtenu BE886438A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/102,504 US4234684A (en) 1979-12-11 1979-12-11 Method of preparing mycophenolic acid glucoside

Publications (1)

Publication Number Publication Date
BE886438A true BE886438A (fr) 1981-06-02

Family

ID=22290205

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/10057A BE886438A (fr) 1979-12-11 1980-12-02 Procede de preparation du glucoside de l'acide mycophenolique, et glucoside ainsi obtenu

Country Status (12)

Country Link
US (1) US4234684A (fr)
EP (1) EP0030460A1 (fr)
JP (1) JPS56121493A (fr)
KR (1) KR840000892B1 (fr)
AR (1) AR224657A1 (fr)
BE (1) BE886438A (fr)
FR (1) FR2471409A1 (fr)
GB (1) GB2065119B (fr)
HU (1) HU182255B (fr)
IE (1) IE50522B1 (fr)
IL (1) IL61617A0 (fr)
IT (1) IT1134642B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID18663A (id) 1996-04-12 1998-04-30 Novartis Ag Komposisi farmasi berlapis enterik
US6471980B2 (en) 2000-12-22 2002-10-29 Avantec Vascular Corporation Intravascular delivery of mycophenolic acid
US7077859B2 (en) 2000-12-22 2006-07-18 Avantec Vascular Corporation Apparatus and methods for variably controlled substance delivery from implanted prostheses
US7083642B2 (en) 2000-12-22 2006-08-01 Avantec Vascular Corporation Delivery of therapeutic capable agents
DE602004018674D1 (de) * 2003-10-29 2009-02-05 Mallinckrodt Inc Grosstechnisches verfahren zur abtrennung und aufreinigung von fentanyl durch präparative umkehrphasenchromatographie
EP2321421A4 (fr) * 2008-09-10 2013-01-09 Ipca Lab Ltd Procédé de préparation d acide mycophénolique, son sel et ses dérivés esters
CN103834701A (zh) * 2014-03-12 2014-06-04 江苏九阳生物制药有限公司 一种麦考酚酸的发酵工艺及培养基配比

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1232583B (de) * 1960-03-14 1967-01-19 Madaus & Co Dr Verfahren zur Gewinnung von organischen Verbindungen auf biochemischem Wege
US3932619A (en) * 1973-02-01 1976-01-13 Eli Lilly And Company Metabolite A-27106 and processes for its preparation and use

Also Published As

Publication number Publication date
FR2471409A1 (fr) 1981-06-19
IL61617A0 (en) 1981-01-30
IT1134642B (it) 1986-08-13
GB2065119B (en) 1983-04-13
HU182255B (en) 1983-12-28
IT8026523A0 (it) 1980-12-09
US4234684A (en) 1980-11-18
JPS56121493A (en) 1981-09-24
KR840000892B1 (ko) 1984-06-26
EP0030460A1 (fr) 1981-06-17
AR224657A1 (es) 1981-12-30
IE50522B1 (en) 1986-04-30
KR830004414A (ko) 1983-07-13
GB2065119A (en) 1981-06-24
IE802542L (en) 1981-06-11

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ELI LILLY AND CY

Effective date: 19861231