BE877327A - Octahydro-pyrazolo (3,4-g) quinoleines et leur utilisation therapeutique - Google Patents

Octahydro-pyrazolo (3,4-g) quinoleines et leur utilisation therapeutique

Info

Publication number
BE877327A
BE877327A BE1/9436A BE1009436A BE877327A BE 877327 A BE877327 A BE 877327A BE 1/9436 A BE1/9436 A BE 1/9436A BE 1009436 A BE1009436 A BE 1009436A BE 877327 A BE877327 A BE 877327A
Authority
BE
Belgium
Prior art keywords
emi
mixture
essentially
evaporation
reaction mixture
Prior art date
Application number
BE1/9436A
Other languages
English (en)
French (fr)
Inventor
E C Kornfeld
N J Bach
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BE877327A publication Critical patent/BE877327A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Pyridine Compounds (AREA)
BE1/9436A 1979-01-22 1979-06-28 Octahydro-pyrazolo (3,4-g) quinoleines et leur utilisation therapeutique BE877327A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US506179A 1979-01-22 1979-01-22

Publications (1)

Publication Number Publication Date
BE877327A true BE877327A (fr) 1979-12-28

Family

ID=21713955

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/9436A BE877327A (fr) 1979-01-22 1979-06-28 Octahydro-pyrazolo (3,4-g) quinoleines et leur utilisation therapeutique

Country Status (8)

Country Link
JP (2) JPS55100387A (ko)
KR (1) KR840002068B1 (ko)
AT (1) AT372947B (ko)
BE (1) BE877327A (ko)
CS (3) CS227009B2 (ko)
HU (2) HU180234B (ko)
PL (1) PL126234B1 (ko)
SU (3) SU1360586A3 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59222477A (ja) * 1983-05-31 1984-12-14 イーライ・リリー・アンド・カンパニー トランス−ｄｌ−１−アルキル−６−アルコキシオクタヒドロキノリン
US5472998A (en) * 1994-09-16 1995-12-05 E. I. Du Pont De Nemours And Company Polymeric additive for cathodic electrocoating compositions for improved throw power

Also Published As

Publication number Publication date
SU1024008A3 (ru) 1983-06-15
CS443982A2 (cs) 1984-12-14
CS237331B2 (en) 1985-07-16
KR830010076A (ko) 1983-12-26
HU180234B (en) 1983-02-28
HU190390B (en) 1986-07-28
ATA21781A (de) 1983-04-15
KR840002068B1 (ko) 1984-11-09
SU986295A3 (ru) 1982-12-30
CS227009B2 (en) 1984-04-16
JPS55100387A (en) 1980-07-31
AT372947B (de) 1983-11-25
JPS6231717B2 (ko) 1987-07-09
JPS6322073A (ja) 1988-01-29
CS515881A2 (en) 1985-09-17
SU1360586A3 (ru) 1987-12-15
PL126234B1 (en) 1983-07-30

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ELI LILLY AND CY

Effective date: 19920630