BE796274A - Nouvelles dihydropyridines dissymetriques substituees sur l'azote - Google Patents

Nouvelles dihydropyridines dissymetriques substituees sur l'azote

Info

Publication number
BE796274A
BE796274A BE128369A BE128369A BE796274A BE 796274 A BE796274 A BE 796274A BE 128369 A BE128369 A BE 128369A BE 128369 A BE128369 A BE 128369A BE 796274 A BE796274 A BE 796274A
Authority
BE
Belgium
Prior art keywords
dissymetric
dihydropyridines
new nitrogen
nitrogen substitute
substitute
Prior art date
Application number
BE128369A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BE796274A publication Critical patent/BE796274A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BE128369A 1972-03-06 1973-03-05 Nouvelles dihydropyridines dissymetriques substituees sur l'azote BE796274A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2210672A DE2210672C3 (de) 1972-03-06 1972-03-06 N-substituierte unsymmetrische 1 ^-Dihydropyridin-S^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
BE796274A true BE796274A (fr) 1973-09-05

Family

ID=5838025

Family Applications (1)

Application Number Title Priority Date Filing Date
BE128369A BE796274A (fr) 1972-03-06 1973-03-05 Nouvelles dihydropyridines dissymetriques substituees sur l'azote

Country Status (25)

Country Link
US (1) US3883540A (fr)
JP (1) JPS5626657B2 (fr)
KR (1) KR780000010B1 (fr)
AT (1) AT324335B (fr)
AU (1) AU468879B2 (fr)
BE (1) BE796274A (fr)
BG (2) BG22389A3 (fr)
CA (1) CA1045138A (fr)
CH (2) CH578530A5 (fr)
CS (2) CS173649B2 (fr)
DD (1) DD107456A5 (fr)
DE (1) DE2210672C3 (fr)
DK (1) DK136900C (fr)
ES (2) ES412319A1 (fr)
FR (1) FR2183674B1 (fr)
GB (1) GB1384031A (fr)
HU (1) HU164867B (fr)
IE (1) IE37366B1 (fr)
IL (1) IL41668A (fr)
LU (1) LU67146A1 (fr)
NL (1) NL7303135A (fr)
PL (2) PL92117B1 (fr)
RO (2) RO63067A (fr)
SU (6) SU466656A3 (fr)
ZA (1) ZA731500B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4031104A (en) * 1972-04-18 1977-06-21 Bayer Aktiengesellschaft 1,4-Dihydropyridine carboxylic acid esters
US3974278A (en) * 1973-07-12 1976-08-10 Bayer Aktiengesellschaft 1,4-Dihydropyridine esters
CH607848A5 (fr) * 1974-06-04 1978-11-30 Bayer Ag
FR2320750A1 (fr) * 1975-08-12 1977-03-11 Hexachimie Dihydro-1,4 pyridines et leur application therapeutique
US4466972A (en) * 1977-06-20 1984-08-21 Sandoz Ltd. Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them
SU798099A1 (ru) * 1978-03-06 1981-01-23 Ордена Трудового Красного Знамениинститут Органического Синтезаан Латвийской Ccp 1-Бензил-2,6-диметил-4-о-или-M-НиТРОфЕНил-3,5-диэТОКСиКАРбОНил- 1,4-дигидРОпиРидиНы, пРО Вл ющиЕКОРОНАРОдилАТиРующую АКТиВНОСТь
SE429652B (sv) * 1978-06-30 1983-09-19 Haessle Ab 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
DE2847236A1 (de) * 1978-10-31 1980-05-14 Bayer Ag Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4497808A (en) * 1981-12-30 1985-02-05 Ciba-Geigy Corporation N-Oxide compounds useful in the treatment of cardiovascular ailments
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
IL68604A0 (en) * 1982-05-21 1983-09-30 Haessle Ab Processes for preparing therapeutically active dihydropyridines and intermediates for the processes
DE3312283A1 (de) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
US5237089A (en) * 1986-02-07 1993-08-17 Basf Aktiengesellschaft Nitro or amino substituted phenylalkyl or phenylalkenyl carboxylic acid derivatives
DE3724399A1 (de) * 1987-07-23 1989-02-02 Basf Ag Phenylalkenylcarbonsaeuren und deren ester
US5216172A (en) * 1988-02-24 1993-06-01 Ajinomoto Co., Inc. 1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells
EP0330470A3 (fr) * 1988-02-24 1992-01-02 Ajinomoto Co., Inc. Dérivés de 1,4-dihydropyridine utiles contre les cellules tumorales
DE4011695A1 (de) * 1990-04-11 1991-10-17 Bayer Ag Verwendung von n-alkylierten 1,4-dihydropyridindicarbonsaeureestern als arzneimittel, neue verbindungen und verfahren zu ihrer herstellung
DE4125271A1 (de) * 1991-07-31 1993-02-11 Bayer Ag Neue n-alkylierte 1,4-dihydropyridindicarbonsaeureester
DE4133257A1 (de) * 1991-10-08 1993-04-15 Bayer Ag N-methyl-nimodipin, verfahren zu seiner herstellung und seine verwendung als zerebraltherapeutikum
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
EP1889198B1 (fr) 2005-04-28 2014-11-26 Proteus Digital Health, Inc. Systeme pharma-informatique
WO2008036682A2 (fr) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Traitement des troubles hépatiques par l'administration de conjugués de protéine associée au récepteur (rap)
DK3395372T3 (da) 2009-02-20 2022-04-19 Enhanx Biopharm Inc System til afgivelse af glutathion-baseret medikament
EP2427178B1 (fr) 2009-05-06 2023-01-04 Laboratory Skin Care, Inc. Compositions pour libération dermique comprenant des complexes principe actif-particule de phosphate de calcium et procédés d'utilisation associés
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
EP2782573B1 (fr) * 2011-11-24 2019-10-09 Richter Gedeon Nyrt. Dérivés de 1,4-dihydropyridine ayant une activité modulant hsp
JP7411994B2 (ja) 2020-03-19 2024-01-12 昌史 星野 腰枕および腰枕セット

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2359329A (en) * 1943-06-18 1944-10-03 Burroughs Wellcome Co Quinoline substituted dihydropyridines
DE2013431C3 (de) * 1970-03-20 1979-12-20 Bayer Ag, 5090 Leverkusen 4-Azidophenyl-l,4-dihydropyridin-3,5-dicarbonsäureester
DE1963186C3 (de) * 1969-12-17 1979-02-15 Bayer Ag, 5090 Leverkusen Schwefelhaltige 1,4-Dihydropyridin-33-dicarbonsäureester
DE2117572C3 (de) * 1971-04-10 1980-03-20 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin ^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
DE2210672C3 (de) 1980-03-20
BG22389A3 (fr) 1977-02-20
DE2210672B2 (de) 1979-07-12
IL41668A0 (en) 1973-05-31
CH579049A5 (fr) 1976-08-31
PL89257B1 (fr) 1976-11-30
RO62798A (fr) 1977-11-15
JPS4899179A (fr) 1973-12-15
SU470958A3 (ru) 1975-05-15
ES412319A1 (es) 1976-05-01
BG20351A3 (fr) 1975-11-05
KR780000010B1 (en) 1978-03-04
NL7303135A (fr) 1973-09-10
IE37366L (en) 1973-09-06
JPS5626657B2 (fr) 1981-06-19
RO63067A (fr) 1978-05-15
SU466656A3 (ru) 1975-04-05
GB1384031A (en) 1975-02-19
CS173624B2 (fr) 1977-02-28
AT324335B (de) 1975-08-25
ZA731500B (en) 1973-11-28
IE37366B1 (en) 1977-07-06
DK136900B (da) 1977-12-12
ES439487A1 (es) 1977-02-01
DK136900C (da) 1978-05-22
AU468879B2 (en) 1975-03-27
LU67146A1 (fr) 1973-05-22
SU451241A3 (ru) 1974-11-25
CH578530A5 (fr) 1976-08-13
IL41668A (en) 1977-02-28
FR2183674B1 (fr) 1976-10-22
US3883540A (en) 1975-05-13
AU5287673A (en) 1975-03-27
CS173649B2 (fr) 1977-02-28
CA1045138A (fr) 1978-12-26
FR2183674A1 (fr) 1973-12-21
DD107456A5 (fr) 1974-08-05
SU457217A3 (ru) 1975-01-15
SU468416A3 (ru) 1975-04-25
PL92117B1 (fr) 1977-03-31
DE2210672A1 (de) 1973-09-20
HU164867B (fr) 1974-05-28
SU464111A3 (ru) 1975-03-15

Similar Documents

Publication Publication Date Title
BE796274A (fr) Nouvelles dihydropyridines dissymetriques substituees sur l'azote
BE794946A (fr) Nouvelles compositions d'esters
AT341657B (de) Damenbinde
BE825146A (fr) Complexes d'antitranspiration
FR2346009A1 (fr) Nouvelles 1-benzazolylalcoyl-piperidines substituees en position 4''
FR2283545A1 (fr) Panneau d'affichage
SE7505473L (sv) 1,4-dihydropyridiner
BE811489A (fr) Phenoxyalcanecarboxylates d'hydroxyalkyltheophyllines
BE800798A (fr) Preparation d'uree
IT1045864B (it) Accouplement d'ambre
FR2286482A1 (fr) Procede d'encapsulation
BE832692A (fr) Production d'hydrocarbures
BE829856A (fr) Derives d'oxacyclohexane
BE827507A (fr) Panneau d'affichage
BE802991A (fr) Carbamates d'isocyanophenyle
FR2286686A1 (fr) Machine d'oxycoupage
FR2322719A1 (fr) Machine d'extrusion
FR2293923A1 (fr) 11-desoxy-o-pentanorprostaglandines substituees en position 15
FR2314732A1 (fr) Solution d'iodophore
TR18322A (tr) N-n-diallildikloroasetamid'in
FR2279711A1 (fr) Production d'hydroxy-cetones
BE808376A (fr) Derives d'indane-1-carboxamide
BE798026R (fr) Polymeres contenant de l'azote
FR2306310A2 (fr) Element d'espacement
BE824297A (fr) Soutien d'ecartement

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: BAYER A.G.

Effective date: 19840305