DK136900C - Analogifremgangsmaade til fremstilling af usymmetriske 1,4-dihydropyridindicarboxylsyreestere - Google Patents
Analogifremgangsmaade til fremstilling af usymmetriske 1,4-dihydropyridindicarboxylsyreestereInfo
- Publication number
- DK136900C DK136900C DK118573A DK118573A DK136900C DK 136900 C DK136900 C DK 136900C DK 118573 A DK118573 A DK 118573A DK 118573 A DK118573 A DK 118573A DK 136900 C DK136900 C DK 136900C
- Authority
- DK
- Denmark
- Prior art keywords
- unusymmetric
- dihydropyridin
- preparing
- dicarboxylic acid
- acid esters
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2210672A DE2210672C3 (de) | 1972-03-06 | 1972-03-06 | N-substituierte unsymmetrische 1 ^-Dihydropyridin-S^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK136900B DK136900B (da) | 1977-12-12 |
| DK136900C true DK136900C (da) | 1978-05-22 |
Family
ID=5838025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK118573A DK136900C (da) | 1972-03-06 | 1973-03-05 | Analogifremgangsmaade til fremstilling af usymmetriske 1,4-dihydropyridindicarboxylsyreestere |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US3883540A (da) |
| JP (1) | JPS5626657B2 (da) |
| KR (1) | KR780000010B1 (da) |
| AT (1) | AT324335B (da) |
| AU (1) | AU468879B2 (da) |
| BE (1) | BE796274A (da) |
| BG (2) | BG20351A3 (da) |
| CA (1) | CA1045138A (da) |
| CH (2) | CH578530A5 (da) |
| CS (2) | CS173649B2 (da) |
| DD (1) | DD107456A5 (da) |
| DE (1) | DE2210672C3 (da) |
| DK (1) | DK136900C (da) |
| ES (2) | ES412319A1 (da) |
| FR (1) | FR2183674B1 (da) |
| GB (1) | GB1384031A (da) |
| HU (1) | HU164867B (da) |
| IE (1) | IE37366B1 (da) |
| IL (1) | IL41668A (da) |
| LU (1) | LU67146A1 (da) |
| NL (1) | NL7303135A (da) |
| PL (2) | PL89257B1 (da) |
| RO (2) | RO63067A (da) |
| SU (6) | SU468416A3 (da) |
| ZA (1) | ZA731500B (da) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4031104A (en) * | 1972-04-18 | 1977-06-21 | Bayer Aktiengesellschaft | 1,4-Dihydropyridine carboxylic acid esters |
| US3974278A (en) * | 1973-07-12 | 1976-08-10 | Bayer Aktiengesellschaft | 1,4-Dihydropyridine esters |
| CH607848A5 (da) * | 1974-06-04 | 1978-11-30 | Bayer Ag | |
| FR2320750A1 (fr) * | 1975-08-12 | 1977-03-11 | Hexachimie | Dihydro-1,4 pyridines et leur application therapeutique |
| US4466972A (en) * | 1977-06-20 | 1984-08-21 | Sandoz Ltd. | Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them |
| SU798099A1 (ru) * | 1978-03-06 | 1981-01-23 | Ордена Трудового Красного Знамениинститут Органического Синтезаан Латвийской Ccp | 1-Бензил-2,6-диметил-4-о-или-M-НиТРОфЕНил-3,5-диэТОКСиКАРбОНил- 1,4-дигидРОпиРидиНы, пРО Вл ющиЕКОРОНАРОдилАТиРующую АКТиВНОСТь |
| SE429652B (sv) * | 1978-06-30 | 1983-09-19 | Haessle Ab | 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester |
| DE2847236A1 (de) * | 1978-10-31 | 1980-05-14 | Bayer Ag | Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| US4497808A (en) * | 1981-12-30 | 1985-02-05 | Ciba-Geigy Corporation | N-Oxide compounds useful in the treatment of cardiovascular ailments |
| DE3208628A1 (de) * | 1982-03-10 | 1983-09-22 | Bayer Ag, 5090 Leverkusen | Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| IL68604A0 (en) * | 1982-05-21 | 1983-09-30 | Haessle Ab | Processes for preparing therapeutically active dihydropyridines and intermediates for the processes |
| DE3312283A1 (de) * | 1983-04-05 | 1984-10-18 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern |
| US5237089A (en) * | 1986-02-07 | 1993-08-17 | Basf Aktiengesellschaft | Nitro or amino substituted phenylalkyl or phenylalkenyl carboxylic acid derivatives |
| DE3724399A1 (de) * | 1987-07-23 | 1989-02-02 | Basf Ag | Phenylalkenylcarbonsaeuren und deren ester |
| US5216172A (en) * | 1988-02-24 | 1993-06-01 | Ajinomoto Co., Inc. | 1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells |
| EP0330470A3 (en) * | 1988-02-24 | 1992-01-02 | Ajinomoto Co., Inc. | 1,4-dihydropyridine derivatives useful against tumour cells |
| DE4011695A1 (de) * | 1990-04-11 | 1991-10-17 | Bayer Ag | Verwendung von n-alkylierten 1,4-dihydropyridindicarbonsaeureestern als arzneimittel, neue verbindungen und verfahren zu ihrer herstellung |
| DE4125271A1 (de) * | 1991-07-31 | 1993-02-11 | Bayer Ag | Neue n-alkylierte 1,4-dihydropyridindicarbonsaeureester |
| DE4133257A1 (de) * | 1991-10-08 | 1993-04-15 | Bayer Ag | N-methyl-nimodipin, verfahren zu seiner herstellung und seine verwendung als zerebraltherapeutikum |
| CA2450073C (en) | 2001-07-25 | 2017-08-29 | Biomarin Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| EP2392258B1 (en) | 2005-04-28 | 2014-10-08 | Proteus Digital Health, Inc. | Pharma-informatics system |
| KR20090071598A (ko) | 2006-09-18 | 2009-07-01 | 랩터 파마슈티컬 인코포레이티드 | 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료 |
| EP2398500B1 (en) | 2009-02-20 | 2019-03-13 | 2-BBB Medicines B.V. | Glutathione-based drug delivery system |
| MY163048A (en) | 2009-05-06 | 2017-08-15 | Laboratory Skin Care Inc | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| CN110606822A (zh) * | 2011-11-24 | 2019-12-24 | 里克特吉迪翁公司 | 具有hsp调节活性的1,4-二氢吡啶衍生物 |
| JP7411994B2 (ja) | 2020-03-19 | 2024-01-12 | 昌史 星野 | 腰枕および腰枕セット |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2359329A (en) * | 1943-06-18 | 1944-10-03 | Burroughs Wellcome Co | Quinoline substituted dihydropyridines |
| DE2013431C3 (de) * | 1970-03-20 | 1979-12-20 | Bayer Ag, 5090 Leverkusen | 4-Azidophenyl-l,4-dihydropyridin-3,5-dicarbonsäureester |
| DE1963186C3 (de) * | 1969-12-17 | 1979-02-15 | Bayer Ag, 5090 Leverkusen | Schwefelhaltige 1,4-Dihydropyridin-33-dicarbonsäureester |
| DE2117572C3 (de) * | 1971-04-10 | 1980-03-20 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin ^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
-
1972
- 1972-03-06 DE DE2210672A patent/DE2210672C3/de not_active Expired
-
1973
- 1973-02-13 RO RO7300082609A patent/RO63067A/ro unknown
- 1973-02-13 RO RO7300073831A patent/RO62798A/ro unknown
- 1973-02-26 DD DD169053A patent/DD107456A5/xx unknown
- 1973-02-28 SU SU1888153A patent/SU468416A3/ru active
- 1973-02-28 BG BG24471A patent/BG20351A3/xx unknown
- 1973-02-28 SU SU1888533A patent/SU464111A3/ru active
- 1973-02-28 US US336605A patent/US3883540A/en not_active Expired - Lifetime
- 1973-02-28 SU SU1888150A patent/SU470958A3/ru active
- 1973-02-28 SU SU1888525A patent/SU457217A3/ru active
- 1973-02-28 SU SU1888529A patent/SU451241A3/ru active
- 1973-02-28 BG BG22856A patent/BG22389A3/xx unknown
- 1973-02-28 SU SU1888534A patent/SU466656A3/ru active
- 1973-03-02 JP JP2444773A patent/JPS5626657B2/ja not_active Expired
- 1973-03-02 AU AU52876/73A patent/AU468879B2/en not_active Expired
- 1973-03-02 IL IL7341668A patent/IL41668A/en unknown
- 1973-03-02 CH CH313773A patent/CH578530A5/xx not_active IP Right Cessation
- 1973-03-02 CH CH237476A patent/CH579049A5/xx not_active IP Right Cessation
- 1973-03-02 LU LU67146A patent/LU67146A1/xx unknown
- 1973-03-03 PL PL1973161009A patent/PL89257B1/pl unknown
- 1973-03-03 PL PL1973181661A patent/PL92117B1/pl unknown
- 1973-03-05 CA CA165,184A patent/CA1045138A/en not_active Expired
- 1973-03-05 ES ES412319A patent/ES412319A1/es not_active Expired
- 1973-03-05 BE BE128369A patent/BE796274A/xx not_active IP Right Cessation
- 1973-03-05 ZA ZA731500A patent/ZA731500B/xx unknown
- 1973-03-05 IE IE342/73A patent/IE37366B1/xx unknown
- 1973-03-05 DK DK118573A patent/DK136900C/da not_active IP Right Cessation
- 1973-03-05 KR KR7300354A patent/KR780000010B1/ko active
- 1973-03-06 HU HUBA2887A patent/HU164867B/hu unknown
- 1973-03-06 NL NL7303135A patent/NL7303135A/xx not_active Application Discontinuation
- 1973-03-06 FR FR7307921A patent/FR2183674B1/fr not_active Expired
- 1973-03-06 CS CS5080A patent/CS173649B2/cs unknown
- 1973-03-06 CS CS1591A patent/CS173624B2/cs unknown
- 1973-03-06 GB GB1075473A patent/GB1384031A/en not_active Expired
- 1973-03-06 AT AT196873A patent/AT324335B/de not_active IP Right Cessation
-
1975
- 1975-07-16 ES ES439487A patent/ES439487A1/es not_active Expired
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |