BE784012A - Nouvelles ((phenyl-4 piperazynyl-1)-2 ethyl) - 3 indolines substituees et procede de leur preparation - Google Patents

Nouvelles ((phenyl-4 piperazynyl-1)-2 ethyl) - 3 indolines substituees et procede de leur preparation

Info

Publication number
BE784012A
BE784012A BE784012A BE784012A BE784012A BE 784012 A BE784012 A BE 784012A BE 784012 A BE784012 A BE 784012A BE 784012 A BE784012 A BE 784012A BE 784012 A BE784012 A BE 784012A
Authority
BE
Belgium
Prior art keywords
piperazynyl
news
phenyl
ethyl
preparation
Prior art date
Application number
BE784012A
Other languages
English (en)
Inventor
G R Allen
F J Mcevoy
V G Devries
D B Moraneet R Littell
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of BE784012A publication Critical patent/BE784012A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE784012A 1971-05-27 1972-05-26 Nouvelles ((phenyl-4 piperazynyl-1)-2 ethyl) - 3 indolines substituees et procede de leur preparation BE784012A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14770071A 1971-05-27 1971-05-27

Publications (1)

Publication Number Publication Date
BE784012A true BE784012A (fr) 1972-11-27

Family

ID=22522572

Family Applications (1)

Application Number Title Priority Date Filing Date
BE784012A BE784012A (fr) 1971-05-27 1972-05-26 Nouvelles ((phenyl-4 piperazynyl-1)-2 ethyl) - 3 indolines substituees et procede de leur preparation

Country Status (20)

Country Link
US (1) US3751416A (fr)
AR (4) AR194595A1 (fr)
BE (1) BE784012A (fr)
BG (5) BG20791A3 (fr)
CA (1) CA1014154A (fr)
CH (5) CH583701A5 (fr)
CS (3) CS185245B2 (fr)
DD (1) DD100471A5 (fr)
DE (1) DE2225765A1 (fr)
ES (4) ES403245A1 (fr)
FR (1) FR2139158B1 (fr)
GB (2) GB1382917A (fr)
HU (3) HU167203B (fr)
NL (1) NL7207129A (fr)
NO (1) NO136795C (fr)
PL (4) PL92627B1 (fr)
RO (4) RO64489A (fr)
SE (4) SE395455B (fr)
SU (4) SU489322A3 (fr)
ZA (1) ZA722916B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888860A (en) * 1974-01-07 1975-06-10 Colgate Palmolive Co 3-(2-(4-thienoylpiperazin-1-yl)ethyl)indoles
US4089853A (en) * 1977-02-09 1978-05-16 American Cyanamid Company Process for the preparation of cis-5,6-dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)-ethyl]indoline
FR2421900A1 (fr) * 1977-03-17 1979-11-02 Sauba Lab Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques
GR65270B (en) 1978-10-10 1980-07-31 Fujisawa Pharmaceutical Co Isatin derivatives and processes for the preparation thereof
US4224330A (en) * 1979-09-13 1980-09-23 Zoecon Corporation Esters and thiolesters of benzothienyl acids
US4411900A (en) * 1980-01-03 1983-10-25 Fujisawa Pharmaceutical Co., Ltd. Benzhydrylpiperozinyl thiazole derivatives and pharmaceutical composition comprising the same
US4302589A (en) * 1980-05-08 1981-11-24 American Cyanamid Company Cis-mono and disubstituted-2-methyl-3-[(piperazinyl) and (piperidino)ethyl]indolines, intermediates for their preparation and methods of preparation
CA1248531A (fr) * 1984-04-17 1989-01-10 Jeffrey C. Watkins Derives de substitution en 4 d'acides piperazine-2- carboxyliques
JPH05255089A (ja) * 1991-12-18 1993-10-05 Sanwa Kagaku Kenkyusho Co Ltd 抗ウイルス剤

Also Published As

Publication number Publication date
BG18866A3 (fr) 1975-03-20
RO63715A (fr) 1978-10-15
ES409281A1 (es) 1976-03-16
DD100471A5 (fr) 1973-09-20
CH582142A5 (fr) 1976-11-30
DE2225765A1 (de) 1972-12-07
GB1382917A (en) 1975-02-05
AR208647A1 (es) 1977-02-28
CH583700A5 (fr) 1977-01-14
NO136795B (no) 1977-08-01
HU166178B (fr) 1975-02-28
CS185244B2 (en) 1978-09-15
CS185245B2 (en) 1978-09-15
PL92635B1 (fr) 1977-04-30
PL92634B1 (fr) 1977-04-30
CS185203B2 (en) 1978-09-15
PL81987B1 (fr) 1975-10-31
RO60145A (fr) 1976-09-15
SU575024A3 (ru) 1977-09-30
SE7600531L (sv) 1976-01-20
CH579563A5 (fr) 1976-09-15
BG19593A3 (fr) 1975-06-25
CA1014154A (en) 1977-07-19
ES403245A1 (es) 1975-04-16
SE397525B (sv) 1977-11-07
SU489322A3 (ru) 1975-10-25
HU168720B (fr) 1976-07-28
ZA722916B (en) 1973-02-28
BG20791A3 (fr) 1975-12-20
FR2139158A1 (fr) 1973-01-05
SU489321A3 (ru) 1975-10-25
AR194595A1 (es) 1973-07-31
ES409282A1 (es) 1976-03-16
NL7207129A (fr) 1972-11-29
ES409284A1 (es) 1976-03-16
RO64489A (fr) 1979-05-15
SU488408A3 (ru) 1975-10-15
AU4191872A (en) 1973-11-08
US3751416A (en) 1973-08-07
HU167203B (fr) 1975-09-27
FR2139158B1 (fr) 1975-10-17
AR208646A1 (es) 1977-02-28
CH583701A5 (fr) 1977-01-14
GB1382916A (en) 1975-02-05
SE395455B (sv) 1977-08-15
AR210562A1 (es) 1977-08-31
NO136795C (no) 1977-11-09
RO63730A (fr) 1978-11-15
BG19151A3 (fr) 1975-04-30
CH582172A5 (fr) 1976-11-30
PL92627B1 (fr) 1977-04-30
SE397524B (sv) 1977-11-07
BG19594A3 (fr) 1975-06-25

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