FR2289200A1 - Nouvelles 4-(1-aminoalcoylidene)-1-aryl-3,4-dihydro-2-benzazepines et leur procede de preparation - Google Patents

Nouvelles 4-(1-aminoalcoylidene)-1-aryl-3,4-dihydro-2-benzazepines et leur procede de preparation

Info

Publication number
FR2289200A1
FR2289200A1 FR7600447A FR7600447A FR2289200A1 FR 2289200 A1 FR2289200 A1 FR 2289200A1 FR 7600447 A FR7600447 A FR 7600447A FR 7600447 A FR7600447 A FR 7600447A FR 2289200 A1 FR2289200 A1 FR 2289200A1
Authority
FR
France
Prior art keywords
aminoalcoylidene
benzazepines
news
dihydro
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7600447A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of FR2289200A1 publication Critical patent/FR2289200A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/16—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/20—Free hydroxyl or mercaptan
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7600447A 1974-06-03 1976-01-09 Nouvelles 4-(1-aminoalcoylidene)-1-aryl-3,4-dihydro-2-benzazepines et leur procede de preparation Withdrawn FR2289200A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/475,474 US3947585A (en) 1974-06-03 1974-06-03 Pyrazolobenzazepines

Publications (1)

Publication Number Publication Date
FR2289200A1 true FR2289200A1 (fr) 1976-05-28

Family

ID=23887726

Family Applications (3)

Application Number Title Priority Date Filing Date
FR7517130A Withdrawn FR2272662A1 (fr) 1974-06-03 1975-06-02
FR7600447A Withdrawn FR2289200A1 (fr) 1974-06-03 1976-01-09 Nouvelles 4-(1-aminoalcoylidene)-1-aryl-3,4-dihydro-2-benzazepines et leur procede de preparation
FR7600446A Withdrawn FR2289187A1 (fr) 1974-06-03 1976-01-09 Nouvelles 2-(5- ou 3-pyrazolyl)-benzophenones, leur procede de preparation et leur application en tant que medicament

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7517130A Withdrawn FR2272662A1 (fr) 1974-06-03 1975-06-02

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7600446A Withdrawn FR2289187A1 (fr) 1974-06-03 1976-01-09 Nouvelles 2-(5- ou 3-pyrazolyl)-benzophenones, leur procede de preparation et leur application en tant que medicament

Country Status (12)

Country Link
US (1) US3947585A (fr)
JP (1) JPS516995A (fr)
AU (1) AU8176175A (fr)
BE (1) BE829779A (fr)
DE (3) DE2543382A1 (fr)
DK (1) DK237075A (fr)
FI (1) FI751622A (fr)
FR (3) FR2272662A1 (fr)
IL (1) IL47404A0 (fr)
NO (1) NO751845L (fr)
SE (1) SE7505899L (fr)
ZA (2) ZA752296B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5461463U (fr) * 1977-10-07 1979-04-28
JPS54180099U (fr) * 1978-06-05 1979-12-19
FR2450833A1 (fr) * 1979-02-07 1980-10-03 Hoffmann La Roche Derives de benzazepine
US4243589A (en) * 1979-11-30 1981-01-06 Hoffmann-La Roche Inc. Triazolobenzazepines and processes for their production
ZA815357B (en) * 1980-08-05 1982-07-28 Hoffmann La Roche Benzazepine derivatives
US4354973A (en) * 1980-08-05 1982-10-19 Hoffmann-La Roche Inc. Pyrrolo[3,4-d][2]benzazepines
US4379765A (en) * 1980-08-05 1983-04-12 Hoffmann-La Roche Inc. Pyrazolobenzazepines
US4405518A (en) * 1981-07-23 1983-09-20 Hoffmann-La Roche Inc. Pyrrolo[3,4-d] [2] benzazepines
US4436662A (en) 1982-06-28 1984-03-13 Hoffmann-La Roche Inc. Pyrrolo[3,4-d][2]benzazepinones
PT1905773E (pt) 2004-05-14 2012-10-25 Millennium Pharm Inc Compostos e métodos para inibir a progressão mitótica por inibição da quinase aurora

Also Published As

Publication number Publication date
SE7505899L (sv) 1975-12-04
DE2524048A1 (de) 1976-01-15
ZA752296B (en) 1976-03-31
FI751622A (fr) 1975-12-04
FR2272662A1 (fr) 1975-12-26
JPS516995A (fr) 1976-01-20
IL47404A0 (en) 1975-08-31
BE829779A (fr) 1975-12-02
ZA753555B (en) 1976-04-28
DK237075A (da) 1975-12-04
DE2543383A1 (de) 1976-01-29
NO751845L (fr) 1975-12-04
DE2543382A1 (de) 1976-01-29
US3947585A (en) 1976-03-30
AU8176175A (en) 1976-12-09
FR2289187A1 (fr) 1976-05-28

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Legal Events

Date Code Title Description
ST Notification of lapse