BE2014C028I2 - - Google Patents

Info

Publication number
BE2014C028I2
BE2014C028I2 BE2014C028C BE2014C028C BE2014C028I2 BE 2014C028 I2 BE2014C028 I2 BE 2014C028I2 BE 2014C028 C BE2014C028 C BE 2014C028C BE 2014C028 C BE2014C028 C BE 2014C028C BE 2014C028 I2 BE2014C028 I2 BE 2014C028I2
Authority
BE
Belgium
Prior art keywords
treatment
tumors
bone
radium
bones
Prior art date
Application number
BE2014C028C
Other languages
English (en)
French (fr)
Original Assignee
Bayer As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer As filed Critical Bayer As
Publication of BE2014C028I2 publication Critical patent/BE2014C028I2/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Radiation-Therapy Devices (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
BE2014C028C 1999-01-04 2014-05-07 BE2014C028I2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO990001A NO310544B1 (no) 1999-01-04 1999-01-04 Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
PCT/NO1999/000392 WO2000040275A2 (en) 1999-01-04 1999-12-17 The preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning

Publications (1)

Publication Number Publication Date
BE2014C028I2 true BE2014C028I2 (uk) 2019-03-05

Family

ID=19902803

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2014C028C BE2014C028I2 (uk) 1999-01-04 2014-05-07

Country Status (25)

Country Link
US (2) US6635234B1 (uk)
EP (1) EP1140212B1 (uk)
JP (2) JP4649044B2 (uk)
KR (1) KR100671387B1 (uk)
CN (2) CN1767078B (uk)
AT (1) ATE331534T1 (uk)
AU (1) AU774991B2 (uk)
BE (1) BE2014C028I2 (uk)
BR (1) BR9916768A (uk)
CA (1) CA2358498C (uk)
CY (2) CY1105634T1 (uk)
DE (1) DE69932183T2 (uk)
DK (1) DK1140212T3 (uk)
EA (1) EA003496B1 (uk)
ES (1) ES2268888T3 (uk)
HK (1) HK1090750A1 (uk)
IL (1) IL144135A0 (uk)
LU (1) LU92425I2 (uk)
MX (1) MXPA01006823A (uk)
NO (2) NO310544B1 (uk)
NZ (3) NZ534618A (uk)
PT (1) PT1140212E (uk)
TR (3) TR200102707T2 (uk)
WO (1) WO2000040275A2 (uk)
ZA (1) ZA200105431B (uk)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO310544B1 (no) * 1999-01-04 2001-07-23 Algeta As Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO314537B1 (no) * 1999-12-06 2003-04-07 Anticancer Therapeutic Inv Sa Reseptorbindende konjugater
NO313180B1 (no) 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
AUPQ923100A0 (en) * 2000-08-07 2000-08-31 Peplin Research Pty Ltd Treatment of prostate cancer
CA2472578A1 (en) * 2002-01-24 2003-07-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Anti-cancer combination and use thereof
GB0213261D0 (en) * 2002-06-10 2002-07-17 Anticancer Therapeutic Inv Sa Method
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
JP4998916B2 (ja) * 2003-04-30 2012-08-15 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド 放射線治療のための方法及び装置
WO2005079867A2 (en) * 2004-02-20 2005-09-01 Algeta As Alpha-emitting hydroxyapatite particles
DE102004022200B4 (de) * 2004-05-05 2006-07-20 Actinium Pharmaceuticals, Inc. Radium-Target sowie Verfahren zu seiner Herstellung
US7914766B1 (en) * 2004-06-03 2011-03-29 Ut-Battelle Llc Inorganic resins for clinical use of 213Bi generators
GB0423565D0 (en) * 2004-10-22 2004-11-24 Algeta As Formulation
ES2701409T3 (es) * 2005-07-26 2019-02-22 Alpha Tau Medical Ltd Una fuente radiactiva superficial y un método para producirla
US8709380B1 (en) * 2006-02-07 2014-04-29 Sirius Medicine, Llc Targeting agents for enhancing radiation therapy
DE102006008023B4 (de) 2006-02-21 2008-05-29 Actinium Pharmaceuticals, Inc. Verfahren zum Reinigen von 225Ac aus bestrahlten 226Ra-Targets
EP2796575B8 (en) * 2006-09-08 2020-04-01 Actinium Pharmaceuticals, Inc. Method for the purification of radium from different sources
EP2116539A1 (en) 2008-04-25 2009-11-11 Laboratorios Del. Dr. Esteve, S.A. 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof
EP2353598A1 (en) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for use in the prevention and/or treatment of postoperative pain
EP2353591A1 (en) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof
GB201002508D0 (en) 2010-02-12 2010-03-31 Algeta As Product
GB201007354D0 (en) * 2010-04-30 2010-06-16 Algeta Asa Method
GB201007353D0 (en) 2010-04-30 2010-06-16 Algeta Asa Method
EP2388005A1 (en) 2010-05-21 2011-11-23 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy
EP2415471A1 (en) 2010-08-03 2012-02-08 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in opioid-induced hyperalgesia
EP2524694A1 (en) 2011-05-19 2012-11-21 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in diabetes type-2 associated pain
CA2895356A1 (en) 2012-12-19 2014-06-26 Bayer Pharma Aktiengesellschaft Combination comprising radium-223 for the treatment of cancer
GB201314718D0 (en) * 2013-08-16 2013-10-02 Algeta As Quantification method
EP3077003A1 (en) 2013-12-03 2016-10-12 Bayer Pharma Aktiengesellschaft Combination of pi3k-inhibitors
CN105934256B (zh) 2013-12-03 2019-12-27 拜耳制药股份公司 Pi3k-抑制剂的组合产品
WO2015091508A1 (en) 2013-12-17 2015-06-25 Laboratorios Del Dr. Esteve, S.A. SEROTONIN-NOREPINEPHRINE REUPTAKE INHIBITORS (SNRIs) AND SIGMA RECEPTOR LIGANDS COMBINATIONS
WO2016083739A1 (fr) 2014-11-26 2016-06-02 Rhodia Operations Composition de lanthane et d'actinium-227
GB201600154D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope preparation method
GB201600153D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope preparation method
CZ2016821A3 (cs) * 2016-12-22 2018-07-04 České vysoké učení technické v Praze Kombinace pro radionuklidovou terapii pro použití jako léčivo
UY37616A (es) 2017-02-24 2018-09-28 Bayer Ag Combinación de inhibidores de quinasa atr con sal de radio-223
MX2019013346A (es) 2017-05-11 2020-01-20 Alpha Tau Medical Ltd Recubrimientos polimericos para dispositivos de braquiterapia.
KR102715288B1 (ko) 2018-04-02 2024-10-11 알파 타우 메디컬 리미티드 방사성 핵종의 제어된 방출
EP3563875A1 (en) * 2018-05-04 2019-11-06 Ceské vysoké ucení technické v Praze Radium for radionuclide therapy, in combination with calcium metabolism affecting treatment
LU100900B1 (de) * 2018-08-10 2020-02-17 Thomas Melchior Homann Verbindungen zur modulation von a-ketoglutarsäure (2kg)-abhängigen oxygenasen
FR3086186B1 (fr) * 2018-09-26 2022-01-28 Orano Med Procede de production de plomb-212 a partir d'une solution aqueuse comprenant du thorium-228 et ses descendants
FR3088769B1 (fr) * 2018-11-15 2020-12-25 Orano Med Procede de preparation d'au moins un generateur a haute teneur en radium-228
WO2020180756A1 (en) * 2019-03-01 2020-09-10 Washington University Compositions and methods for radiotherapy using chelated radiotherapeutic agents and non-target tissue blockade
RU2752845C1 (ru) * 2020-05-13 2021-08-11 Акционерное Общество "Наука И Инновации" Способ получения высокочистого радия-223
AU2021400142A1 (en) * 2020-12-16 2023-06-22 Alpha Tau Medical Ltd. Diffusing alpha-emitters radiation therapy with enhanced beta treatment
CN113066598B (zh) * 2021-03-25 2023-08-08 中国科学院近代物理研究所 一种从高能质子束辐照232Th靶引起的散裂反应中分离纯化223Ra的方法
US12070621B2 (en) 2021-06-10 2024-08-27 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for pancreatic cancer
US12076581B2 (en) 2021-06-10 2024-09-03 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for glioblastoma
US12070620B2 (en) 2021-06-10 2024-08-27 Alpha Tau Medical Ltd. Activity levels for diffusing alpha-emitter radiation therapy
US12042668B2 (en) 2021-06-10 2024-07-23 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for squamous cell carcinoma
US12076582B2 (en) 2021-06-10 2024-09-03 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for colorectal cancer
US12064643B2 (en) 2021-06-10 2024-08-20 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for breast cancer
US12076583B2 (en) 2021-06-10 2024-09-03 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for melanoma
US11964168B2 (en) 2021-06-10 2024-04-23 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy for prostate cancer
AU2023221939A1 (en) 2022-02-21 2024-08-22 Bayer Healthcare Llc System, method and device for delivery of a therapeutic or diagnostic agent
AU2023221437A1 (en) 2022-02-21 2024-08-22 Bayer Healthcare Llc System, method and device for delivery of a therapeutic or diagnostic agent.
CN115869658A (zh) * 2022-12-29 2023-03-31 中国核动力研究设计院 用于制备Ra-223的分离系统及其分离方法、应用和制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH668489A5 (de) * 1982-01-22 1988-12-30 Vnii Mineralnogo Syrya Radiometrisches verfahren zur bestimmung der konzentration natuerlicher radiumisotope und einrichtung zur durchfuehrung des verfahrens.
AU626348B2 (en) * 1988-10-14 1992-07-30 Mallinckrodt, Inc. Radiolabelled particulate composition
US4970062A (en) * 1989-05-30 1990-11-13 The United States Of America As Represented By The United States Department Of Energy Colloid labelled with radionuclide and method
EP0614377A1 (en) * 1991-11-14 1994-09-14 Battelle Memorial Institute Method for diagnosing and treating cancer
IL109666A0 (en) * 1993-05-17 1994-08-26 Immunomedics Inc A targeting composition containing a biotin- or avidinprotein conjugate and methods for the use thereof
US5809394A (en) * 1996-12-13 1998-09-15 Battelle Memorial Institute Methods of separating short half-life radionuclides from a mixture of radionuclides
US6117413A (en) * 1997-11-12 2000-09-12 Battelle Memorial Institute Radionuclide-binding compound, a radionuclide delivery system, a method of making a radium complexing compound, a method of extracting a radionuclide, and a method of delivering a radionuclide
NO310544B1 (no) * 1999-01-04 2001-07-23 Algeta As Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO314537B1 (no) * 1999-12-06 2003-04-07 Anticancer Therapeutic Inv Sa Reseptorbindende konjugater
NO312708B1 (no) * 2000-02-21 2002-06-24 Anticancer Therapeutic Inv Sa Radioaktive liposomer til terapi
NO313180B1 (no) * 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
GB0213261D0 (en) * 2002-06-10 2002-07-17 Anticancer Therapeutic Inv Sa Method
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
US20060228297A1 (en) * 2003-04-15 2006-10-12 Roy Larsen Thorium-227 for use in radiotherapy of soft tissue disease

Also Published As

Publication number Publication date
KR20010092772A (ko) 2001-10-26
TR200201442T2 (tr) 2002-08-21
ATE331534T1 (de) 2006-07-15
NZ513135A (en) 2004-09-24
KR100671387B1 (ko) 2007-01-19
LU92425I2 (fr) 2014-06-10
CN1335779A (zh) 2002-02-13
NO2014010I1 (no) 2014-06-02
CA2358498C (en) 2008-09-16
PT1140212E (pt) 2006-11-30
US20030206857A1 (en) 2003-11-06
AU774991B2 (en) 2004-07-15
DE69932183T2 (de) 2007-05-16
JP5433490B2 (ja) 2014-03-05
DK1140212T3 (da) 2006-10-09
US6635234B1 (en) 2003-10-21
CY1105634T1 (el) 2010-12-22
JP2010168397A (ja) 2010-08-05
NO310544B1 (no) 2001-07-23
JP2002534399A (ja) 2002-10-15
CA2358498A1 (en) 2000-07-13
NZ534618A (en) 2006-03-31
ZA200105431B (en) 2002-07-02
ES2268888T3 (es) 2007-03-16
TR200201440T2 (tr) 2002-08-21
CY2014020I1 (el) 2015-12-09
HK1090750A1 (en) 2006-12-29
WO2000040275A3 (en) 2001-06-21
CN1767078A (zh) 2006-05-03
CN1767078B (zh) 2012-01-11
EA003496B1 (ru) 2003-06-26
NO990001D0 (no) 1999-01-04
NO2014010I2 (uk) 2014-05-09
MXPA01006823A (es) 2003-07-14
BR9916768A (pt) 2001-12-04
CN1194764C (zh) 2005-03-30
CY2014020I2 (el) 2015-12-09
IL144135A0 (en) 2002-05-23
NZ545023A (en) 2007-08-31
NO990001L (no) 2000-07-05
WO2000040275A2 (en) 2000-07-13
EP1140212A2 (en) 2001-10-10
EA200100642A1 (ru) 2002-02-28
TR200102707T2 (tr) 2002-03-21
AU1700400A (en) 2000-07-24
JP4649044B2 (ja) 2011-03-09
EP1140212B1 (en) 2006-06-28
DE69932183D1 (de) 2006-08-10

Similar Documents

Publication Publication Date Title
NO2014010I2 (uk)
MY155913A (en) Chimeric anti-cd20 antibody treatment of patients receiving bmt or pbsc transpants
MXPA03006771A (es) Anticuerpos modificados y metodos de uso.
WO2002041837A3 (en) Treatment of mucositis
FR2721198B1 (fr) Prothèse implantable souple, utilisée en chirurgie pour l'augmentation de volume ou la reconstruction des tissus mous, notamment prothèse mammaire.
MY164077A (en) Compositions and uses of et743 for treating cancer
HK1047707A1 (zh) (+)-曲馬朵、o-去甲曲馬朵或(+)-o-去甲曲馬朵、o-去甲-n-單-去甲-曲馬朵或(+)-o-去甲-n-單-去甲-曲馬朵治療尿失禁的用途
EP1162956B8 (en) Compositions and methods for improving integrity of compromised body passageways and cavities
AU1233701A (en) Methods and compositions for treating atheroma, tumors and other neoplastic tissue
AU2001234831A1 (en) Magnetoliposome composition for targeted treatment of biological tissue and associated methods
EP1139750A4 (en) BONE SIALOPROTEIN-BASED TOXIC GENE THERAPY FOR TREATING CALCIFIED TUMORS AND TISSUES
AU1907001A (en) Instrument (osteotome) for forming holes in bone tissue, preferably in jaw-bone tissue
UA32302A (uk) Спосіб усунення післяопераційних деформацій м'яких тканин
MD1268B2 (en) Method for surgical treatment of meta-physar fracture of children should bone distal part
AU5760596A (en) Component b as cicatrizant
UA32173A (uk) Спосіб лікування недорозвиненої середньої зони лицевого скелету
UA33331A (uk) Спосіб профілактики гнійно-септичних ускладнень в післяопераційному періоді
UA32315A (uk) Спосіб накладання шкірного шва
UA32153A (uk) Спосіб формування трансплантату для зведення на промежину при черевно-анальних резекціях прямої кишки
IT1317076B1 (it) Preparato anti-infiammatorio non steroideo (fans) per il trattamentodelle affezioni osteoarticolari e dei tessuti molli, a minore
UA32109A (uk) Спосіб пластики фарингоезофагостоми
UA40998A (uk) Спосіб ампутації гомілки
AU2002217680A1 (en) Surface modification of implants for healing in bone and soft tissue
SI1196159T1 (en) Use of tosylchloramide(s) for treating diseases of the skin, mucous membranes, organs and tissues
UA32174A (uk) Спосіб хірургічного лікування гемангіом надбровної області