AU8940491A - Substituted indolizino(1,2-b)quinolinones - Google Patents

Substituted indolizino(1,2-b)quinolinones

Info

Publication number
AU8940491A
AU8940491A AU89404/91A AU8940491A AU8940491A AU 8940491 A AU8940491 A AU 8940491A AU 89404/91 A AU89404/91 A AU 89404/91A AU 8940491 A AU8940491 A AU 8940491A AU 8940491 A AU8940491 A AU 8940491A
Authority
AU
Australia
Prior art keywords
compound
llff
quinolin
lower alkyl
indolizino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU89404/91A
Other languages
English (en)
Inventor
Hameed Sheik Allaudeen
David Alan Berges
Robert Philip Hertzberg
Randall Keith Johnson
William Dennis Kingsbury
Stephen Robert Petteway
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of AU8940491A publication Critical patent/AU8940491A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU89404/91A 1990-10-31 1991-10-30 Substituted indolizino(1,2-b)quinolinones Abandoned AU8940491A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60621690A 1990-10-31 1990-10-31
US606216 1990-10-31
US78306391A 1991-10-25 1991-10-25
US783063 1991-10-25

Publications (1)

Publication Number Publication Date
AU8940491A true AU8940491A (en) 1992-05-26

Family

ID=27085175

Family Applications (1)

Application Number Title Priority Date Filing Date
AU89404/91A Abandoned AU8940491A (en) 1990-10-31 1991-10-30 Substituted indolizino(1,2-b)quinolinones

Country Status (9)

Country Link
EP (1) EP0555347A4 (xx)
JP (1) JPH06502642A (xx)
KR (1) KR930702289A (xx)
AU (1) AU8940491A (xx)
CA (1) CA2095219A1 (xx)
IE (1) IE913790A1 (xx)
NZ (1) NZ240406A (xx)
PT (1) PT99412A (xx)
WO (1) WO1992007856A1 (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883255A (en) * 1990-10-31 1999-03-16 Smithkline Beecham Corporation Substituted indolizino 1,2-b!quinolinones
EP0637960A4 (en) * 1992-04-17 1995-06-07 Smithkline Beecham Corp INDOLIZINO 1,2-b] SUBSTITUTED QUINOLINONES.
JPH08509742A (ja) * 1993-05-03 1996-10-15 スミスクライン・ビーチャム・コーポレイション 置換メチレンジオキシ［３’，４’：６，７］インドリジノ［１，２−ｂ］キノリノン
US5491237A (en) * 1994-05-03 1996-02-13 Glaxo Wellcome Inc. Intermediates in pharmaceutical camptothecin preparation
WO1997001539A1 (en) * 1995-06-27 1997-01-16 Takeda Chemical Industries, Ltd. 4-acylamino(halogeno) alkyl-quinoline derivatives, their preparation and their use as melatonin agonists
EA001400B1 (ru) 1995-11-02 2001-02-26 Глаксо Веллкам Инк. Способ получения производных камптотецина
US6559309B2 (en) 1996-11-01 2003-05-06 Osi Pharmaceuticals, Inc. Preparation of a camptothecin derivative by intramolecular cyclisation
JP3046258B2 (ja) * 1997-04-11 2000-05-29 株式会社ヤクルト本社 １−クロロカルボニル−４−ピペリジノピペリジンまたはその塩酸塩の製造方法
US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
WO2003059884A1 (en) 2001-12-21 2003-07-24 X-Ceptor Therapeutics, Inc. Modulators of lxr
AU2003225642A1 (en) * 2002-03-01 2003-09-16 Fluorous Techonologies Inc Mappicine analogs, intermediates in the synthesis of mappicine analogs and methods of synthesis of mappicine analogs
US7064202B1 (en) * 2003-05-12 2006-06-20 University Of Kentucky Research Foundation Camptothecin intermediates and prodrugs and methods of preparation thereof
US20050267141A1 (en) 2004-05-28 2005-12-01 Phytogen Life Sciences Inc. Process to prepare camptothecin derivatives
US20050272757A1 (en) * 2004-06-04 2005-12-08 Phytogen Life Sciences Inc. Process to prepare camptothecin derivatives and novel intermediate and compounds thereof
WO2006019955A2 (en) * 2004-07-14 2006-02-23 President And Fellows Of Harvard College Antiviral methods and compositions
US9888690B2 (en) 2011-06-22 2018-02-13 Council Of Scientific & Industrial Research Insecticidal compounds from Nothapodites foetida and process for the extraction thereof
KR101721029B1 (ko) 2014-10-16 2017-03-29 연세대학교 산학협력단 인돌리지노[3,2-c]퀴놀린 유도체, 이의 약제학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 포함하는 낭포성 섬유증 예방 또는 치료용 약학조성물
WO2017014601A1 (ko) * 2015-07-23 2017-01-26 서울대학교 산학협력단 인돌리지노[3,2-ｃ]퀴놀린계 형광 프로브
KR101850607B1 (ko) 2015-07-23 2018-04-19 서울대학교산학협력단 인돌리지노[3,2-ｃ]퀴놀린계 형광 프로브

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5829793B2 (ja) * 1975-02-07 1983-06-24 日本ケミフア （株） ７−アルコキシカルボニル−８−メチルインドリジノ〔１，２−ｂ〕キノリン−９（１１Ｈ）−オンの製法

Also Published As

Publication number Publication date
WO1992007856A1 (en) 1992-05-14
EP0555347A1 (en) 1993-08-18
IE913790A1 (en) 1992-05-22
NZ240406A (en) 1994-05-26
JPH06502642A (ja) 1994-03-24
CA2095219A1 (en) 1992-05-01
EP0555347A4 (en) 1995-01-11
KR930702289A (ko) 1993-09-08
PT99412A (pt) 1992-10-30

Similar Documents

Publication Publication Date Title
AU8940491A (en) Substituted indolizino(1,2-b)quinolinones
Wall et al. Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs
KR100191193B1 (ko) 6환 화합물
ES2254600T3 (es) Nuevos analogos de la camptotecina, procedimientos de preparacion, su aplicacion como medicamentos y las composiciones farmaceuticas que los contienen.
FI91872B (fi) Menetelmä terapeuttisesti aktiivisten pyranoindolitsinokinoliinijohdannaisten valmistamiseksi
DE69726007T2 (de) Prodrogs und analoga von camptothecin und deren verwendung als arzneimittel
JP4138022B2 (ja) テトラヒドロピリド化合物
WO1993016698A1 (en) SUBSTITUTED FURO[3',4':6,7]INDOLIZINO[1,2-b]QUINOLINONES
US5883255A (en) Substituted indolizino 1,2-b!quinolinones
WO1995003803A1 (en) SUBSTITUTED FURO[3',4':6,7]INDOLIZINO[1,2-b]QUINOLINONES
AU684777B2 (en) Substituted methylenedioxy(3',4':6,7)indolizino-(1,2-b)quinolinones
JPS5959665A (ja) 三環式ラクタム類の製造法およびそれらの医薬組成物
WO1993020818A1 (en) SUBSTITUTED INDOLIZINO[1,2-b]QUINOLINONES
US6583150B1 (en) Pharmaceutical composition based on polyaromatic compounds
EP0981528A1 (en) Regioisomeric benzothiopyranopyridines having antitumor activity
JPH07101956A (ja) ヒドロキシカンプトテシン化合物の製法
EP0637960A1 (en) SUBSTITUTED INDOLIZINO 1,2-b]QUINOLINONES
US6762301B2 (en) Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
IE920704A1 (en) Nitrogen oxides of aza- and diaza-anthracenedione¹derivatives as antitumor agents
NO831503L (no) Fremgangsmaate for fremstilling av kondenserte cykloalifatiske derivater av substituerte pyrido (1,2-a) pyrimidiner
IE65892B1 (en) Pyrrolo-pyridine derivatives process and compositions
IL128044A (en) 1, 4, 5, 9-TETRAHYDRO-5-HYDROXY - 5- SUBSTITUTED-OXEPINO [3, 4 - c] - PYRIDINE-3, 9-DIONES AND THEIR PREPARATION
MXPA99005768A (en) Pro-drugs and counterparts of camptothecin, their application as medicines