NZ240406A - Substituted indolizino [1,2-b]quinolin-9(11h)-one derivatives, pharmaceutical formulations and use as antiviral agents - Google Patents

Substituted indolizino [1,2-b]quinolin-9(11h)-one derivatives, pharmaceutical formulations and use as antiviral agents

Info

Publication number
NZ240406A
NZ240406A NZ240406A NZ24040691A NZ240406A NZ 240406 A NZ240406 A NZ 240406A NZ 240406 A NZ240406 A NZ 240406A NZ 24040691 A NZ24040691 A NZ 24040691A NZ 240406 A NZ240406 A NZ 240406A
Authority
NZ
New Zealand
Prior art keywords
quinolin
derivatives
pharmaceutical formulations
antiviral agents
indolizino
Prior art date
Application number
NZ240406A
Other languages
English (en)
Inventor
Sheik Allaudeen Hameed
David Alan Berges
Robert Philip Hertzberg
Randall Keith Johnson
William Dennis Kingsbury
Stephen Robert Petteway
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of NZ240406A publication Critical patent/NZ240406A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NZ240406A 1990-10-31 1991-10-30 Substituted indolizino [1,2-b]quinolin-9(11h)-one derivatives, pharmaceutical formulations and use as antiviral agents NZ240406A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60621690A 1990-10-31 1990-10-31
US78306391A 1991-10-25 1991-10-25

Publications (1)

Publication Number Publication Date
NZ240406A true NZ240406A (en) 1994-05-26

Family

ID=27085175

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ240406A NZ240406A (en) 1990-10-31 1991-10-30 Substituted indolizino [1,2-b]quinolin-9(11h)-one derivatives, pharmaceutical formulations and use as antiviral agents

Country Status (9)

Country Link
EP (1) EP0555347A4 (xx)
JP (1) JPH06502642A (xx)
KR (1) KR930702289A (xx)
AU (1) AU8940491A (xx)
CA (1) CA2095219A1 (xx)
IE (1) IE913790A1 (xx)
NZ (1) NZ240406A (xx)
PT (1) PT99412A (xx)
WO (1) WO1992007856A1 (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883255A (en) * 1990-10-31 1999-03-16 Smithkline Beecham Corporation Substituted indolizino 1,2-b!quinolinones
EP0637960A4 (en) * 1992-04-17 1995-06-07 Smithkline Beecham Corp INDOLIZINO 1,2-b] SUBSTITUTED QUINOLINONES.
MX9403275A (es) * 1993-05-03 1995-01-31 Smithkline Beecham Corp Metilendioxi[3,'4':6,7]indolizino-[1,2-b]quinolinonas substituidas.
US5491237A (en) * 1994-05-03 1996-02-13 Glaxo Wellcome Inc. Intermediates in pharmaceutical camptothecin preparation
US5708005A (en) * 1995-06-27 1998-01-13 Takeda Chemical Industries, Ltd. Quinolines, their production and use
JP3499246B2 (ja) 1995-11-02 2004-02-23 オーエスアイ・ファーマスーティカルズ・インコーポレーテッド カンプトテシン誘導体の製造法
US6559309B2 (en) 1996-11-01 2003-05-06 Osi Pharmaceuticals, Inc. Preparation of a camptothecin derivative by intramolecular cyclisation
JP3046258B2 (ja) * 1997-04-11 2000-05-29 株式会社ヤクルト本社 １−クロロカルボニル−４−ピペリジノピペリジンまたはその塩酸塩の製造方法
ES2421511T3 (es) 2001-12-21 2013-09-03 X Ceptor Therapeutics Inc Moduladores de LXR
US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
WO2003074524A2 (en) * 2002-03-01 2003-09-12 University Of Pittsburgh Mappicine analogs, intermediates in the synthesis of mappicine analogs and methods of synthesis of mappicine analogs
US7064202B1 (en) * 2003-05-12 2006-06-20 University Of Kentucky Research Foundation Camptothecin intermediates and prodrugs and methods of preparation thereof
US20050267141A1 (en) 2004-05-28 2005-12-01 Phytogen Life Sciences Inc. Process to prepare camptothecin derivatives
US20050272757A1 (en) * 2004-06-04 2005-12-08 Phytogen Life Sciences Inc. Process to prepare camptothecin derivatives and novel intermediate and compounds thereof
WO2006019955A2 (en) 2004-07-14 2006-02-23 President And Fellows Of Harvard College Antiviral methods and compositions
WO2012176145A1 (en) * 2011-06-22 2012-12-27 Council Of Scientific & Industrial Research Insecticidal compositions isolated from nothapodites foetida and process for the extraction thereof
KR101721029B1 (ko) 2014-10-16 2017-03-29 연세대학교 산학협력단 인돌리지노[3,2-c]퀴놀린 유도체, 이의 약제학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 포함하는 낭포성 섬유증 예방 또는 치료용 약학조성물
WO2017014601A1 (ko) * 2015-07-23 2017-01-26 서울대학교 산학협력단 인돌리지노[3,2-ｃ]퀴놀린계 형광 프로브
KR101850607B1 (ko) 2015-07-23 2018-04-19 서울대학교산학협력단 인돌리지노[3,2-ｃ]퀴놀린계 형광 프로브

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5829793B2 (ja) * 1975-02-07 1983-06-24 日本ケミフア （株） ７−アルコキシカルボニル−８−メチルインドリジノ〔１，２−ｂ〕キノリン−９（１１Ｈ）−オンの製法

Also Published As

Publication number Publication date
AU8940491A (en) 1992-05-26
EP0555347A4 (en) 1995-01-11
CA2095219A1 (en) 1992-05-01
WO1992007856A1 (en) 1992-05-14
IE913790A1 (en) 1992-05-22
KR930702289A (ko) 1993-09-08
JPH06502642A (ja) 1994-03-24
PT99412A (pt) 1992-10-30
EP0555347A1 (en) 1993-08-18

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