AU778776B2 - High sensitivity phage display biomolecule detection - Google Patents

High sensitivity phage display biomolecule detection Download PDF

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Publication number
AU778776B2
AU778776B2 AU44612/00A AU4461200A AU778776B2 AU 778776 B2 AU778776 B2 AU 778776B2 AU 44612/00 A AU44612/00 A AU 44612/00A AU 4461200 A AU4461200 A AU 4461200A AU 778776 B2 AU778776 B2 AU 778776B2
Authority
AU
Australia
Prior art keywords
phage
bound
protein
biomolecule
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU44612/00A
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English (en)
Other versions
AU4461200A (en
Inventor
Carl R. Merril
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United States Department of Health and Human Services
Original Assignee
United States Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by United States Department of Health and Human Services filed Critical United States Department of Health and Human Services
Publication of AU4461200A publication Critical patent/AU4461200A/en
Application granted granted Critical
Publication of AU778776B2 publication Critical patent/AU778776B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU44612/00A 1999-04-14 2000-04-13 High sensitivity phage display biomolecule detection Ceased AU778776B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12921599P 1999-04-14 1999-04-14
US60/129215 1999-04-14
PCT/US2000/010146 WO2000061790A1 (en) 1999-04-14 2000-04-13 High sensitivity phage display biomolecule detection

Publications (2)

Publication Number Publication Date
AU4461200A AU4461200A (en) 2000-11-14
AU778776B2 true AU778776B2 (en) 2004-12-23

Family

ID=22438929

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44612/00A Ceased AU778776B2 (en) 1999-04-14 2000-04-13 High sensitivity phage display biomolecule detection

Country Status (8)

Country Link
US (1) US6740492B2 (enExample)
EP (1) EP1169473B1 (enExample)
JP (1) JP2002541818A (enExample)
AT (1) ATE346162T1 (enExample)
AU (1) AU778776B2 (enExample)
CA (1) CA2368875A1 (enExample)
DE (1) DE60031965D1 (enExample)
WO (1) WO2000061790A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2360282A (en) * 2000-03-17 2001-09-19 Bioinvent Int Ab Making and using micro-arrays of biological materials
WO2003010198A1 (en) * 2001-07-26 2003-02-06 Kenton Srl Identification of specific tumour antigens by selection of cdna libraries with sera and use of said antigens in diagnostic techniques
WO2003011902A1 (en) * 2001-07-27 2003-02-13 Kenton S.R.L. Identification of specific tumour antigens by selection of cdna libraries with sera
JP4601427B2 (ja) * 2002-09-18 2010-12-22 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 細胞上および生物学的混合物中の抗原の検出のための組成物、方法およびキット
GB0304832D0 (en) * 2003-03-04 2003-04-09 Secr Defence Assay method
EP1853696B1 (en) * 2005-02-24 2019-04-17 Life Technologies (Israel) Ltd. Electro-blotting devices, systems, and kits, and methods for their use
US20080193917A1 (en) 2005-05-27 2008-08-14 David Alexander Schofield Biological Detection System and Method
US8066866B2 (en) * 2005-10-17 2011-11-29 Lifescan, Inc. Methods for measuring physiological fluids
EP1963494B1 (en) * 2005-11-29 2014-10-08 The Trustees of The University of Pennsylvania Phage particle diagnostic reagents
CN102150045A (zh) * 2008-07-11 2011-08-10 生命技术公司 增强型电泳检测固相支持物上的分析物
USD738527S1 (en) 2013-05-28 2015-09-08 Life Technologies Corporation Electroblotting apparatus
TWI570243B (zh) * 2015-11-03 2017-02-11 國立清華大學 噬菌體之篩選裝置及方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993011242A1 (fr) * 1991-11-29 1993-06-10 Universite Catholique De Louvain Procede de selection de microorganismes recombinants comportant a leur surface au moins une molecule a activite enzymatique
WO1997000329A2 (en) * 1995-06-14 1997-01-03 Yeda Research And Development Co. Ltd. Modified avidin and streptavidin molecules and use thereof
WO1997022972A2 (en) * 1995-12-15 1997-06-26 Pharmacia & Upjohn Company Method for the simultaneous detection of a therapeutic target for a disease state and its neutralizing antibody-like molecule

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
GB9104411D0 (en) * 1991-03-01 1991-04-17 Elchrom Limited Improvement of gel composition in gels for submerged gel electrophoresis
US5679510A (en) * 1993-04-27 1997-10-21 Hybridon, Inc. Quantitative detection of specific nucleic acid sequences using lambdoid bacteriophages linked by oligonucleotides to solid support
US5650267A (en) * 1993-04-27 1997-07-22 Symbiotech, Inc. Method of detecting compounds utilizing genetically modified lambdoid bacteriophage
US6027877A (en) * 1993-11-04 2000-02-22 Gene Check, Inc. Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, purification of amplified DNA samples and allele identification
US5702892A (en) 1995-05-09 1997-12-30 The United States Of America As Represented By The Department Of Health And Human Services Phage-display of immunoglobulin heavy chain libraries
EP0934526B1 (en) * 1996-10-08 2003-01-08 U-BISys B.V. Methods and means for selecting peptides and proteins having specific affinity for a target

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993011242A1 (fr) * 1991-11-29 1993-06-10 Universite Catholique De Louvain Procede de selection de microorganismes recombinants comportant a leur surface au moins une molecule a activite enzymatique
WO1997000329A2 (en) * 1995-06-14 1997-01-03 Yeda Research And Development Co. Ltd. Modified avidin and streptavidin molecules and use thereof
WO1997022972A2 (en) * 1995-12-15 1997-06-26 Pharmacia & Upjohn Company Method for the simultaneous detection of a therapeutic target for a disease state and its neutralizing antibody-like molecule

Also Published As

Publication number Publication date
EP1169473B1 (en) 2006-11-22
CA2368875A1 (en) 2000-10-19
US6740492B2 (en) 2004-05-25
AU4461200A (en) 2000-11-14
US20020110806A1 (en) 2002-08-15
EP1169473A1 (en) 2002-01-09
DE60031965D1 (de) 2007-01-04
WO2000061790A1 (en) 2000-10-19
JP2002541818A (ja) 2002-12-10
ATE346162T1 (de) 2006-12-15

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