AU762758B2 - Gene encoding labyrinthin, a marker for cancer - Google Patents

Gene encoding labyrinthin, a marker for cancer Download PDF

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Publication number
AU762758B2
AU762758B2 AU29996/99A AU2999699A AU762758B2 AU 762758 B2 AU762758 B2 AU 762758B2 AU 29996/99 A AU29996/99 A AU 29996/99A AU 2999699 A AU2999699 A AU 2999699A AU 762758 B2 AU762758 B2 AU 762758B2
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AU
Australia
Prior art keywords
amino acid
molecule
acid sequence
lab
vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU29996/99A
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English (en)
Other versions
AU2999699A (en
Inventor
James A. Radosevich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ImmvaRx Inc
Original Assignee
Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU2999699A publication Critical patent/AU2999699A/en
Assigned to IMMVARX, INC. reassignment IMMVARX, INC. Alteration of Name(s) of Applicant(s) under S113 Assignors: RADOSEVICH, JAMES A.
Application granted granted Critical
Publication of AU762758B2 publication Critical patent/AU762758B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU29996/99A 1998-03-17 1999-03-11 Gene encoding labyrinthin, a marker for cancer Ceased AU762758B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/040,485 US6166176A (en) 1998-03-17 1998-03-17 Cancer marker protein and peptides thereof
US09/040485 1998-03-17
PCT/US1999/005365 WO1999047683A1 (en) 1998-03-17 1999-03-11 Gene encoding labyrinthin, a marker for cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2003204331A Division AU2003204331B2 (en) 1998-03-17 2003-05-22 Gene Encoding Labyrinthin, A Marker For Cancer

Publications (2)

Publication Number Publication Date
AU2999699A AU2999699A (en) 1999-10-11
AU762758B2 true AU762758B2 (en) 2003-07-03

Family

ID=21911225

Family Applications (2)

Application Number Title Priority Date Filing Date
AU29996/99A Ceased AU762758B2 (en) 1998-03-17 1999-03-11 Gene encoding labyrinthin, a marker for cancer
AU2003204331A Ceased AU2003204331B2 (en) 1998-03-17 2003-05-22 Gene Encoding Labyrinthin, A Marker For Cancer

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2003204331A Ceased AU2003204331B2 (en) 1998-03-17 2003-05-22 Gene Encoding Labyrinthin, A Marker For Cancer

Country Status (14)

Country Link
US (7) US6166176A (https=)
EP (1) EP1062346B1 (https=)
JP (2) JP2002512005A (https=)
CN (2) CN100372938C (https=)
AP (1) AP2000001917A0 (https=)
AT (1) ATE337400T1 (https=)
AU (2) AU762758B2 (https=)
BR (1) BR9908886A (https=)
CA (1) CA2323494A1 (https=)
DE (1) DE69932926T2 (https=)
EA (1) EA003735B1 (https=)
IL (1) IL138208A0 (https=)
OA (1) OA11487A (https=)
WO (1) WO1999047683A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6166176A (en) * 1998-03-17 2000-12-26 Immvarx, Inc. Cancer marker protein and peptides thereof
US20030031670A1 (en) 1999-11-08 2003-02-13 Jack R. Wands Diagnosis and treatment of malignant neoplasms
US6835370B2 (en) 1999-11-08 2004-12-28 Rhode Island Hospital Diagnosis and treatment of malignant neoplasms
US20050123545A1 (en) * 1999-11-08 2005-06-09 Wands Jack R. Diagnosis and treatment of malignant neoplasms
US6682902B2 (en) * 1999-12-16 2004-01-27 Schering Aktiengesellschaft DNA encoding a novel RG1 polypeptide
US7306919B1 (en) 2001-10-31 2007-12-11 Thornthwaite Jerry T Antigen-antibody cancer recognition system
CA2491017A1 (en) * 2002-07-03 2004-01-15 Immunogen, Inc. Antibodies to non-shed muc1 and muc16, and uses thereof
ATE414715T1 (de) * 2003-09-04 2008-12-15 Biomay Ag Hypoallergene polypeptide basierend auf aus fisch gewonnenem parvalbumin
WO2005049802A2 (en) * 2003-11-14 2005-06-02 Massachusetts Institute Of Technology Anti-hydroxylase antibodies and uses thereof
CN100457922C (zh) * 2005-10-20 2009-02-04 康哲医药研究(深圳)有限公司 检测酪丝亮肽抗肝癌效果的方法及所用试剂盒与基因芯片
RU2340896C1 (ru) * 2007-05-17 2008-12-10 Негосударственное научно-исследовательское учреждение "Биомедицинский центр" Способ диагностики онкологических заболеваний
GB201002627D0 (en) 2010-02-16 2010-03-31 Loxbridge Res Llp Aptamer based analyte detection method
JP2022513913A (ja) * 2018-12-13 2022-02-09 ラビアールエックス イミュノロジック セラピューティクス （ユーエスエー） リミテッド がん免疫療法のためのラビリンチンベースのペプチドとその使用
US20220089719A1 (en) * 2019-01-08 2022-03-24 Labyrx Immunologic Therapeutics (Usa) Limited Constructs targeting labyrinthin or a portion thereof and uses thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816402A (en) * 1986-01-07 1989-03-28 Northwestern University Murine hybridoma and diagnostic antibody produced thereby
WO1994004679A1 (en) * 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
US5223604A (en) * 1991-06-25 1993-06-29 S.P.I. Synthetic Peptides Incorporated Pseudomonas exoenzyme s peptide composition and method
US5728819A (en) * 1996-08-02 1998-03-17 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
US5994062A (en) * 1995-10-02 1999-11-30 The United States Of America As Represented By The Department Of Health And Human Services Epithelial protein and DNA thereof for use in early cancer detection
US6166176A (en) * 1998-03-17 2000-12-26 Immvarx, Inc. Cancer marker protein and peptides thereof
US6344548B1 (en) * 1998-06-24 2002-02-05 The Regents Of The University Of California Diacylglycerol o-acyltransferase
US7135617B2 (en) * 1998-07-02 2006-11-14 Calgene Llc Diacylglycerol acyl transferase proteins
US6100077A (en) * 1998-10-01 2000-08-08 The Trustees Of Columbia University In The City Of New York Isolation of a gene encoding diacylglycerol acyltransferase
US20030161831A1 (en) * 2001-02-23 2003-08-28 Sylvaine Cases Mono-and diacylglycerol acyltransferases and methods of use thereof
US7045326B2 (en) * 2001-02-23 2006-05-16 The Regents Of The University Of California Mono- and diacylglycerol acyltransferases and methods of use thereof
JP4481819B2 (ja) * 2002-07-31 2010-06-16 モンサント テクノロジー エルエルシー ジアシルグリセロールアシルトランスフェラーゼ核酸配列および関連生成物
US8685679B2 (en) * 2004-11-04 2014-04-01 E I Du Pont De Nemours And Company Acyltransferase regulation to increase the percent of polyunsaturated fatty acids in total lipids and oils of oleaginous organisms
US8507754B2 (en) * 2009-01-31 2013-08-13 University Of North Texas Engineering lipids in vegetative tissues of plants
CA2804025C (en) * 2010-06-28 2023-02-21 Commonwealth Scientific And Industrial Research Organisation Methods of producing lipids

Also Published As

Publication number Publication date
CN100372938C (zh) 2008-03-05
AU2003204331B2 (en) 2008-02-07
US20110110963A1 (en) 2011-05-12
US20100233711A1 (en) 2010-09-16
US20080249284A1 (en) 2008-10-09
JP2002512005A (ja) 2002-04-23
HK1033151A1 (en) 2001-08-17
AU2999699A (en) 1999-10-11
EP1062346A1 (en) 2000-12-27
DE69932926T2 (de) 2007-05-24
EA200000845A1 (ru) 2001-08-27
CA2323494A1 (en) 1999-09-23
CN1301302A (zh) 2001-06-27
OA11487A (en) 2004-05-04
US6166176A (en) 2000-12-26
US7329743B2 (en) 2008-02-12
AP2000001917A0 (en) 2000-09-30
BR9908886A (pt) 2000-11-21
EA003735B1 (ru) 2003-08-28
US6727080B1 (en) 2004-04-27
DE69932926D1 (de) 2006-10-05
IL138208A0 (en) 2001-10-31
ATE337400T1 (de) 2006-09-15
WO1999047683A1 (en) 1999-09-23
US20100112582A1 (en) 2010-05-06
JP2009165492A (ja) 2009-07-30
WO1999047683A9 (en) 1999-11-18
US8163883B2 (en) 2012-04-24
US7635759B2 (en) 2009-12-22
US20050208508A1 (en) 2005-09-22
CN101260401A (zh) 2008-09-10
EP1062346B1 (en) 2006-08-23

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: IMMVARX, INC.

Free format text: THE FORMER OWNER WAS: JAMES A. RADOSEVICH

SREP Specification republished
FGA Letters patent sealed or granted (standard patent)