DE69932926D1 - Gen kodierend für labyrinthin, einen krebsmarker - Google Patents

Gen kodierend für labyrinthin, einen krebsmarker

Info

Publication number
DE69932926D1
DE69932926D1 DE69932926T DE69932926T DE69932926D1 DE 69932926 D1 DE69932926 D1 DE 69932926D1 DE 69932926 T DE69932926 T DE 69932926T DE 69932926 T DE69932926 T DE 69932926T DE 69932926 D1 DE69932926 D1 DE 69932926D1
Authority
DE
Germany
Prior art keywords
labyrinthine
cancer marker
generating gene
gene
generating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69932926T
Other languages
English (en)
Other versions
DE69932926T2 (de
Inventor
James A Radosevich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ImmvaRx Inc
Original Assignee
ImmvaRx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ImmvaRx Inc filed Critical ImmvaRx Inc
Application granted granted Critical
Publication of DE69932926D1 publication Critical patent/DE69932926D1/de
Publication of DE69932926T2 publication Critical patent/DE69932926T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69932926T 1998-03-17 1999-03-11 Gen kodierend für labyrinthin, einen krebsmarker Expired - Lifetime DE69932926T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40485 1993-03-31
US09/040,485 US6166176A (en) 1998-03-17 1998-03-17 Cancer marker protein and peptides thereof
PCT/US1999/005365 WO1999047683A1 (en) 1998-03-17 1999-03-11 Gene encoding labyrinthin, a marker for cancer

Publications (2)

Publication Number Publication Date
DE69932926D1 true DE69932926D1 (de) 2006-10-05
DE69932926T2 DE69932926T2 (de) 2007-05-24

Family

ID=21911225

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69932926T Expired - Lifetime DE69932926T2 (de) 1998-03-17 1999-03-11 Gen kodierend für labyrinthin, einen krebsmarker

Country Status (15)

Country Link
US (7) US6166176A (de)
EP (1) EP1062346B1 (de)
JP (2) JP2002512005A (de)
CN (2) CN101260401A (de)
AP (1) AP2000001917A0 (de)
AT (1) ATE337400T1 (de)
AU (2) AU762758B2 (de)
BR (1) BR9908886A (de)
CA (1) CA2323494A1 (de)
DE (1) DE69932926T2 (de)
EA (1) EA003735B1 (de)
HK (1) HK1033151A1 (de)
IL (1) IL138208A0 (de)
OA (1) OA11487A (de)
WO (1) WO1999047683A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6166176A (en) * 1998-03-17 2000-12-26 Immvarx, Inc. Cancer marker protein and peptides thereof
US20030031670A1 (en) * 1999-11-08 2003-02-13 Jack R. Wands Diagnosis and treatment of malignant neoplasms
US20050123545A1 (en) * 1999-11-08 2005-06-09 Wands Jack R. Diagnosis and treatment of malignant neoplasms
US6835370B2 (en) * 1999-11-08 2004-12-28 Rhode Island Hospital Diagnosis and treatment of malignant neoplasms
US6682902B2 (en) * 1999-12-16 2004-01-27 Schering Aktiengesellschaft DNA encoding a novel RG1 polypeptide
US7306919B1 (en) 2001-10-31 2007-12-11 Thornthwaite Jerry T Antigen-antibody cancer recognition system
US7202346B2 (en) * 2002-07-03 2007-04-10 Immunogen Inc. Antibodies to non-shed Muc1 and Muc16, and uses thereof
ATE414715T1 (de) * 2003-09-04 2008-12-15 Biomay Ag Hypoallergene polypeptide basierend auf aus fisch gewonnenem parvalbumin
WO2005049802A2 (en) * 2003-11-14 2005-06-02 Massachusetts Institute Of Technology Anti-hydroxylase antibodies and uses thereof
CN100457922C (zh) * 2005-10-20 2009-02-04 康哲医药研究(深圳)有限公司 检测酪丝亮肽抗肝癌效果的方法及所用试剂盒与基因芯片
GB201002627D0 (en) 2010-02-16 2010-03-31 Loxbridge Res Llp Aptamer based analyte detection method
JP2022513913A (ja) * 2018-12-13 2022-02-09 ラビアールエックス イミュノロジック セラピューティクス (ユーエスエー) リミテッド がん免疫療法のためのラビリンチンベースのペプチドとその使用
CA3126063A1 (en) * 2019-01-08 2020-07-16 Labyrx Immunologic Therapeutics (Usa) Limited Constructs targeting labyrinthin or a portion thereof and uses thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816402A (en) * 1986-01-07 1989-03-28 Northwestern University Murine hybridoma and diagnostic antibody produced thereby
WO1994004679A1 (en) * 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
US5223604A (en) * 1991-06-25 1993-06-29 S.P.I. Synthetic Peptides Incorporated Pseudomonas exoenzyme s peptide composition and method
US5728819A (en) * 1996-08-02 1998-03-17 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
US5994062A (en) 1995-10-02 1999-11-30 The United States Of America As Represented By The Department Of Health And Human Services Epithelial protein and DNA thereof for use in early cancer detection
US6166176A (en) 1998-03-17 2000-12-26 Immvarx, Inc. Cancer marker protein and peptides thereof
US6344548B1 (en) * 1998-06-24 2002-02-05 The Regents Of The University Of California Diacylglycerol o-acyltransferase
US7135617B2 (en) * 1998-07-02 2006-11-14 Calgene Llc Diacylglycerol acyl transferase proteins
US6100077A (en) * 1998-10-01 2000-08-08 The Trustees Of Columbia University In The City Of New York Isolation of a gene encoding diacylglycerol acyltransferase
US7045326B2 (en) * 2001-02-23 2006-05-16 The Regents Of The University Of California Mono- and diacylglycerol acyltransferases and methods of use thereof
US20030161831A1 (en) * 2001-02-23 2003-08-28 Sylvaine Cases Mono-and diacylglycerol acyltransferases and methods of use thereof
BR0313536A (pt) * 2002-07-31 2005-06-14 Monsanto Technology Llc Sequencias de ácido nucléico de diacilglicerol acetiltransferase e produtos associados
US8685679B2 (en) * 2004-11-04 2014-04-01 E I Du Pont De Nemours And Company Acyltransferase regulation to increase the percent of polyunsaturated fatty acids in total lipids and oils of oleaginous organisms
WO2010088426A1 (en) * 2009-01-31 2010-08-05 Board Of Regents, The University Of Texas System Engineering lipids in vegetative tissues of plants
WO2012000026A1 (en) * 2010-06-28 2012-01-05 Commonwealth Scientific And Industrial Research Organisation Methods of producing lipids

Also Published As

Publication number Publication date
EA003735B1 (ru) 2003-08-28
EP1062346B1 (de) 2006-08-23
EA200000845A1 (ru) 2001-08-27
US6727080B1 (en) 2004-04-27
ATE337400T1 (de) 2006-09-15
US6166176A (en) 2000-12-26
CN1301302A (zh) 2001-06-27
US8163883B2 (en) 2012-04-24
US20080249284A1 (en) 2008-10-09
HK1033151A1 (en) 2001-08-17
JP2009165492A (ja) 2009-07-30
DE69932926T2 (de) 2007-05-24
AP2000001917A0 (en) 2000-09-30
CN100372938C (zh) 2008-03-05
CN101260401A (zh) 2008-09-10
US20100233711A1 (en) 2010-09-16
AU2003204331B2 (en) 2008-02-07
IL138208A0 (en) 2001-10-31
US7329743B2 (en) 2008-02-12
BR9908886A (pt) 2000-11-21
WO1999047683A1 (en) 1999-09-23
JP2002512005A (ja) 2002-04-23
US20110110963A1 (en) 2011-05-12
OA11487A (en) 2004-05-04
US20050208508A1 (en) 2005-09-22
US20100112582A1 (en) 2010-05-06
US7635759B2 (en) 2009-12-22
AU2999699A (en) 1999-10-11
CA2323494A1 (en) 1999-09-23
EP1062346A1 (de) 2000-12-27
AU762758B2 (en) 2003-07-03
WO1999047683A9 (en) 1999-11-18

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