AU761879B2 - Triterpene compositions and methods for use thereof - Google Patents

Triterpene compositions and methods for use thereof Download PDF

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Publication number
AU761879B2
AU761879B2 AU40871/99A AU4087199A AU761879B2 AU 761879 B2 AU761879 B2 AU 761879B2 AU 40871/99 A AU40871/99 A AU 40871/99A AU 4087199 A AU4087199 A AU 4087199A AU 761879 B2 AU761879 B2 AU 761879B2
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AU
Australia
Prior art keywords
cell
triterpene
composition
mammal
administering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU40871/99A
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English (en)
Other versions
AU4087199A (en
Inventor
Charles J Arntzen
David T. Bailey
Mary Blake
Jordan U. Gutterman
Joseph J. Hoffmann
Gamini S. Jayatilake
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Research Development Foundation
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Research Development Foundation
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Filing date
Publication date
Application filed by Research Development Foundation filed Critical Research Development Foundation
Publication of AU4087199A publication Critical patent/AU4087199A/en
Application granted granted Critical
Publication of AU761879B2 publication Critical patent/AU761879B2/en
Priority to AU2003244612A priority Critical patent/AU2003244612B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H4/00Plant reproduction by tissue culture techniques ; Tissue culture techniques therefor
    • A01H4/005Methods for micropropagation; Vegetative plant propagation using cell or tissue culture techniques
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04Plant cells or tissues

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Alternative & Traditional Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
AU40871/99A 1998-05-19 1999-05-19 Triterpene compositions and methods for use thereof Ceased AU761879B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003244612A AU2003244612B2 (en) 1998-05-19 2003-09-09 Use of plant tissue

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8599798P 1998-05-19 1998-05-19
US60/085997 1998-05-19
US9906698P 1998-09-03 1998-09-03
US60/099066 1998-09-03
PCT/US1999/011041 WO1999059578A1 (fr) 1998-05-19 1999-05-19 Compositions de triterpene et leurs champ d'application

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2003244612A Division AU2003244612B2 (en) 1998-05-19 2003-09-09 Use of plant tissue

Publications (2)

Publication Number Publication Date
AU4087199A AU4087199A (en) 1999-12-06
AU761879B2 true AU761879B2 (en) 2003-06-12

Family

ID=26773317

Family Applications (1)

Application Number Title Priority Date Filing Date
AU40871/99A Ceased AU761879B2 (en) 1998-05-19 1999-05-19 Triterpene compositions and methods for use thereof

Country Status (13)

Country Link
US (8) US6444233B1 (fr)
EP (1) EP1079824B1 (fr)
JP (1) JP4860039B2 (fr)
KR (1) KR100785718B1 (fr)
CN (2) CN1307473A (fr)
AT (1) ATE522220T1 (fr)
AU (1) AU761879B2 (fr)
CA (1) CA2330916C (fr)
DK (1) DK1079824T3 (fr)
IL (2) IL139307A0 (fr)
NZ (2) NZ528940A (fr)
RU (1) RU2244547C2 (fr)
WO (1) WO1999059578A1 (fr)

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2330916C (fr) * 1998-05-19 2011-04-05 Research Development Foundation Compositions de triterpene et leurs champ d'application
EP2204186B1 (fr) 1999-02-17 2016-04-06 CSL Limited Complexes immunogènes et méthodes y relatives
AU5231000A (en) * 1999-06-02 2000-12-28 Oxford Natural Products Plc Combination of glucosamine with herbal extracts of tripterygium, ligustrum and erycibe
US7056491B2 (en) * 2000-11-08 2006-06-06 Wisconsin Alumni Research Foundation Monoterpenes and sesquiterpenes as chemotherapeutic and radiation sensitizers and immunomodulators
WO2002038157A2 (fr) 2000-11-09 2002-05-16 The Hospital For Sick Children Inhibiteurs de la formation et de l'activite de la thromboxane
US20060148732A1 (en) * 2000-11-17 2006-07-06 Gutterman Jordan U Inhibition of NF-kappaB by triterpene compositions
JP2002322076A (ja) * 2001-02-26 2002-11-08 Oji Paper Co Ltd トリプシン阻害剤
US6777004B1 (en) * 2001-03-30 2004-08-17 Council Of Scientific & Industrial Research Composition containing novel compound corniculatonin having antifungi properties and a process for preparing the same
US7736677B2 (en) 2001-06-20 2010-06-15 Metaproteomics, Llc Xanthohumol and tetrahydro-isoalpha acid based protein kinase modulation cancer treatment
US7727561B2 (en) * 2001-08-31 2010-06-01 Pacific Arrow Limited Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
US7524824B2 (en) 2003-09-04 2009-04-28 Pacific Arrow Limited Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
KR100464063B1 (ko) * 2001-11-21 2005-01-06 한국생명공학연구원 세포사멸 유도작용을 갖는 트리테르펜 화합물
BR0107262B1 (pt) * 2001-12-17 2014-04-22 Da Fonseca Clovis Orlando Pereira Composição farmacêutica inalatória
EP1467755A1 (fr) * 2001-12-21 2004-10-20 Antigenics Inc. Compositions comprenant des reactifs immunoreactifs et des saponosides et techniques d'utilisation de ces compositions
TWI241916B (en) * 2001-12-28 2005-10-21 Jian-Shin Yang Method for producing nanometer of natural materials
CA2526943C (fr) 2002-05-28 2011-08-09 The Hospital For Sick Children Compositions comprenant des analogues de l'hepoxiline et leur utilisation dans le traitement du cancer
WO2004019961A1 (fr) * 2002-08-30 2004-03-11 Biopharmacopae Design International Inc. Extraits vegetaux pour le traitement de l'angiogenese et de la metastase
US20090264377A1 (en) * 2002-12-27 2009-10-22 Linda Saxe Einbond Anti-neoplastic compositions comprising extracts of black cohosh
US20090186837A1 (en) * 2002-12-27 2009-07-23 The Trustees Of Columbia University In The City Of New York Anti-neoplastic compositions comprising extracts of black cohosh
US7407675B2 (en) * 2002-12-27 2008-08-05 The Trustees Of Columbia University In The City Of New York Anti-neoplastic compositions comprising extracts of black cohosh
US7700745B2 (en) * 2003-02-28 2010-04-20 Japan Science And Technology Agency Method for separating carbohydrate in glycoside-linkage-having compound, carbohydrate separating system, carbohydrate separating reagent kit, standard sample for carbohydrate separation, and evaluation system
NZ546138A (en) * 2003-10-09 2009-12-24 Pacific Arrow Ltd Composition comprising xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
US7488753B2 (en) * 2003-10-09 2009-02-10 Pacific Arrow Limited Composition comprising triterpene saponins and compounds with angeloyl functional group, methods for preparing same and uses thereof
US8614197B2 (en) * 2003-10-09 2013-12-24 Pacific Arrow Limited Anti-tumor compounds with angeloyl groups
US20050095209A1 (en) * 2003-10-31 2005-05-05 Be! Products, Inc. Nail Application Containing Gotu Kola
WO2006053415A1 (fr) * 2004-11-18 2006-05-26 Biopharmacopae Design International Inc. Extraits de plantes et leurs utilisations en dermatologie
US7388126B2 (en) * 2003-12-19 2008-06-17 Monsanto Technology Llc Use of nitric oxide modulators in Agrobacterium-mediated plant transformation
US8735558B2 (en) 2005-02-14 2014-05-27 Pacific Arrow Limited Blocking the migration or metastasis of cancer cells by affecting adhesion proteins and the uses of new compounds thereof
US9382285B2 (en) 2004-09-07 2016-07-05 Pacific Arrow Limited Methods and compounds for modulating the secretion or expression of adhesion proteins or angiopoietins of cells
JP4488852B2 (ja) * 2004-09-17 2010-06-23 味の素ゼネラルフーヅ株式会社 体内脂肪低減作用を有する組成物
US7780974B2 (en) * 2004-09-20 2010-08-24 Research Development Foundation Avicin coated stents
US7727401B2 (en) * 2004-11-09 2010-06-01 Air Products And Chemicals, Inc. Selective purification of mono-terpenes for removal of oxygen containing species
US20090018146A1 (en) * 2005-01-27 2009-01-15 Research Development Corporation Combination Therapy with Triterpenoid Compounds and Proteasome Inhibitors
US20080274557A1 (en) * 2005-03-03 2008-11-06 Indiana University Research And Technology Permethylation Of Oligosaccharides
US7311050B2 (en) * 2005-04-19 2007-12-25 Kamterter Ii, L.L.C. Systems for the control and use of fluids and particles
US7536962B2 (en) * 2005-04-19 2009-05-26 Kamterter Ii, L.L.C. Systems for the control and use of fluids and particles
US8308075B2 (en) 2005-04-19 2012-11-13 Kamterter Products, Llc Systems for the control and use of fluids and particles
US8586719B2 (en) 2005-04-27 2013-11-19 Pacific Arrow Limited Triterpenes for modulating gene expression and cell membrane, and as antiprotozoal agents
AU2006247067B2 (en) * 2005-05-18 2012-06-07 Novartis Ag Methods for diagnosis and treatment of proliferative disorders mediated by CD40 signaling
ES2429564T3 (es) * 2005-05-18 2013-11-15 Novartis Ag Procedimientos para el diagnóstico y tratamiento de enfermedades que tienen un componente autoinmune y/o inflamatorio
WO2007011985A1 (fr) * 2005-07-18 2007-01-25 Duke University Compositions pour la thioesterification reversible de proteines de signalisation et techniques d'utilisation de celles-ci
US8068991B2 (en) 2005-11-30 2011-11-29 The Invention Science Fund I, Llc Systems and methods for transmitting pathogen related information and responding
US8297028B2 (en) 2006-06-14 2012-10-30 The Invention Science Fund I, Llc Individualized pharmaceutical selection and packaging
US8000981B2 (en) 2005-11-30 2011-08-16 The Invention Science Fund I, Llc Methods and systems related to receiving nutraceutical associated information
US10296720B2 (en) 2005-11-30 2019-05-21 Gearbox Llc Computational systems and methods related to nutraceuticals
US8340944B2 (en) 2005-11-30 2012-12-25 The Invention Science Fund I, Llc Computational and/or control systems and methods related to nutraceutical agent selection and dosing
US7974856B2 (en) 2005-11-30 2011-07-05 The Invention Science Fund I, Llc Computational systems and methods related to nutraceuticals
US7827042B2 (en) 2005-11-30 2010-11-02 The Invention Science Fund I, Inc Methods and systems related to transmission of nutraceutical associated information
US7927787B2 (en) 2006-06-28 2011-04-19 The Invention Science Fund I, Llc Methods and systems for analysis of nutraceutical associated components
KR101300336B1 (ko) * 2006-01-24 2013-08-28 아지노모또 제네럴 푸즈, 인크. 혈압의 강하 작용 및/또는 상승 억제 작용을 갖는 조성물 및 이를 함유하는 음식물
WO2007101202A1 (fr) * 2006-02-27 2007-09-07 Research Development Foundation Ikb ciblant des cellules et ses methodes d'utilisation
WO2007118335A1 (fr) 2006-04-19 2007-10-25 Evolva S.A. Enantiomeres d'analogues de l'hepoxiline
US20070264298A1 (en) * 2006-05-10 2007-11-15 Stephen W. Lee Harvestwinner
JP4771882B2 (ja) * 2006-07-21 2011-09-14 味の素ゼネラルフーヅ株式会社 糖尿病または糖尿病性合併症の治療、予防、または改善作用を有する組成物およびこれを含有する飲料
WO2008014563A1 (fr) * 2006-08-03 2008-02-07 Oncology Research International Limited Procédés et compositions destinés à favoriser l'effet de thérapies anti-cancer
EA016653B1 (ru) * 2006-08-03 2012-06-29 Онколоджи Рисерч Интернешнл Лимитед Способы и композиции для ингибирования ангиогенеза
US8822440B2 (en) * 2006-10-10 2014-09-02 Mayo Foundation For Medical Education And Research Inhibiting cyclin D polypeptides
US20090105203A1 (en) * 2006-10-16 2009-04-23 Myriad Genetics, Incorporated Compounds for treating viral infections
DE102006061517A1 (de) * 2006-12-18 2008-06-19 Eberhard-Karls-Universität Tübingen Universitätsklinikum Angioinhibin
US20090274722A1 (en) * 2007-01-29 2009-11-05 Ligums John E Therapeutic Composition for the Treatment of BPH and ED
WO2008094873A1 (fr) * 2007-01-29 2008-08-07 Ligums John E Composition thérapeutique pour l'hypertrophie bénigne de la prostate (bph)
KR101163215B1 (ko) 2007-05-26 2012-07-06 한국생명공학연구원 헐떡이풀 추출물 또는 이로부터 분리된 트리테르펜화합물을 유효성분으로 함유하는 암 질환의 예방 및 치료용조성물
US20090068325A1 (en) * 2007-09-10 2009-03-12 Gil Depicciotto Method of treatment of fresh produce
US7795311B2 (en) * 2007-10-15 2010-09-14 Pittsburg State University Methods and compositions for the management of soil-borne fungal diseases
CN101167787B (zh) * 2007-10-17 2011-06-22 江南大学 抑制血管生成的合欢属植物提取物的组合物及其制备和应用
US20110117008A1 (en) * 2007-11-26 2011-05-19 Research Development Foundation Use of avicins to deliver therapeutic and diagnostic agents
US20090258096A1 (en) * 2008-04-11 2009-10-15 Bionovo, Inc. Anticancer Methods Employing Extracts of Gleditsia sinensis Lam
US20120277308A1 (en) 2010-07-16 2012-11-01 Pacific Arrow Limited compounds for treating cancer and other diseases
US9499577B2 (en) 2009-07-16 2016-11-22 Pacific Arrow Limited Natural and synthetic compounds for treating cancer and other diseases
US9434677B2 (en) 2009-07-16 2016-09-06 Pacific Arrow Limited Natural and synthetic compounds for treating cancer and other diseases
US8771652B2 (en) * 2009-09-17 2014-07-08 New York University Methods of blocking ultraviolet radiation and promoting skin growth using terpenes and terpenoids
WO2011080579A2 (fr) * 2009-12-30 2011-07-07 Himalaya Global Holdings Limited Composition à base d'herbes médicinales pour lutter contre les troubles inflammatoires
US8698496B2 (en) * 2010-09-20 2014-04-15 The General Hospital Corporation Method for two-dimensional correlation magnetic resonance spectroscopy
PL2624702T3 (pl) 2010-10-06 2016-09-30 Kompozycje przeciwko tworzeniu biofilmów oraz sposoby ich zastosowania
EP2529633B1 (fr) * 2011-06-01 2014-08-06 Symrise AG Préparations consommables oralement comprenant du triterpène et du triterpènglycoside au goût sucré
WO2012170467A1 (fr) 2011-06-07 2012-12-13 New York University Compositions et procédés pour restaurer la couche cornée et traiter des maladies dermatologiques
WO2012177825A1 (fr) 2011-06-21 2012-12-27 Bvw Holding Ag Dispositif médical comportant de l'acide boswellique
US20130269537A1 (en) 2012-04-16 2013-10-17 Eugenio Minvielle Conditioning system for nutritional substances
US9175030B2 (en) 2012-02-24 2015-11-03 Jordan Gutterman Derivatives of avicin D and methods of making and using thereof
US20130269538A1 (en) 2012-04-16 2013-10-17 Eugenio Minvielle Transformation system for nutritional substances
US8490862B1 (en) 2012-04-16 2013-07-23 Eugenio Minvielle Transformation system for nutritional substances
US9541536B2 (en) 2012-04-16 2017-01-10 Eugenio Minvielle Preservation system for nutritional substances
US10219531B2 (en) 2012-04-16 2019-03-05 Iceberg Luxembourg S.A.R.L. Preservation system for nutritional substances
US9429920B2 (en) 2012-04-16 2016-08-30 Eugenio Minvielle Instructions for conditioning nutritional substances
US9460633B2 (en) 2012-04-16 2016-10-04 Eugenio Minvielle Conditioner with sensors for nutritional substances
US9072317B2 (en) 2012-04-16 2015-07-07 Eugenio Minvielle Transformation system for nutritional substances
US9564064B2 (en) 2012-04-16 2017-02-07 Eugenio Minvielle Conditioner with weight sensors for nutritional substances
US9016193B2 (en) 2012-04-16 2015-04-28 Eugenio Minvielle Logistic transport system for nutritional substances
US9436170B2 (en) 2012-04-16 2016-09-06 Eugenio Minvielle Appliances with weight sensors for nutritional substances
US9528972B2 (en) 2012-04-16 2016-12-27 Eugenio Minvielle Dynamic recipe control
US9171061B2 (en) 2012-04-16 2015-10-27 Eugenio Minvielle Local storage and conditioning systems for nutritional substances
US8851365B2 (en) * 2012-04-16 2014-10-07 Eugenio Minvielle Adaptive storage and conditioning systems for nutritional substances
US20140069838A1 (en) 2012-04-16 2014-03-13 Eugenio Minvielle Nutritional Substance Label System For Adaptive Conditioning
US9080997B2 (en) 2012-04-16 2015-07-14 Eugenio Minvielle Local storage and conditioning systems for nutritional substances
US8550365B1 (en) 2012-04-16 2013-10-08 Eugenio Minvielle System for managing the nutritional content for nutritional substances
US8733631B2 (en) 2012-04-16 2014-05-27 Eugenio Minvielle Local storage and conditioning systems for nutritional substances
US9414623B2 (en) 2012-04-16 2016-08-16 Eugenio Minvielle Transformation and dynamic identification system for nutritional substances
US9121840B2 (en) 2012-04-16 2015-09-01 Eugenio Minvielle Logistic transport system for nutritional substances
US9069340B2 (en) 2012-04-16 2015-06-30 Eugenio Minvielle Multi-conditioner control for conditioning nutritional substances
US9702858B1 (en) 2012-04-16 2017-07-11 Iceberg Luxembourg S.A.R.L. Dynamic recipe control
US20140179624A1 (en) 2012-12-20 2014-06-26 Research Development Foundation Cytoprotective derivatives of avicin d and methods of making and using thereof
CN104147089A (zh) * 2013-05-15 2014-11-19 伽蓝(集团)股份有限公司 金合欢提取物、制取方法及其用途
CN104147088A (zh) * 2013-05-15 2014-11-19 伽蓝(集团)股份有限公司 金合欢提取物在抗衰老中的应用
TWI492751B (zh) * 2013-06-04 2015-07-21 Univ Kaohsiung Medical 柴胡皂苷製備之醫藥組合物、其用途及其製備方法
US10790062B2 (en) 2013-10-08 2020-09-29 Eugenio Minvielle System for tracking and optimizing health indices
KR101514145B1 (ko) * 2013-10-14 2015-04-21 동의대학교 산학협력단 마카에리움 쿠스피다툼 추출물을 유효성분으로 포함하는 항암 조성물
KR101523434B1 (ko) * 2013-10-14 2015-05-27 동의대학교 산학협력단 줄베르나디아 글로비플로라 추출물을 유효성분으로 포함하는 항암 조성물
RU2562595C2 (ru) * 2013-10-23 2015-09-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Дальневосточный государственный технический рыбохозяйственный университет" Способ получения продукта, обладающего биологически активными свойствами, из голотурий
RU2562592C2 (ru) * 2013-10-23 2015-09-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Дальневосточный государственный технический рыбохозяйственный университет" Способ получения масляного экстракта из голотурий, обладающего биологически активными свойствами (варианты)
RU2562581C1 (ru) * 2014-01-29 2015-09-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Дальневосточный государственный технический рыбохозяйственный университет" Способ получения биологически активного средства из голотурий, обладающего общеукрепляющими и иммуномодулирующими свойствами
CN105358220A (zh) * 2014-06-03 2016-02-24 高雄医学大学 柴胡皂苷制备的药物组合物、其用途及其制备方法
USD762081S1 (en) 2014-07-29 2016-07-26 Eugenio Minvielle Device for food preservation and preparation
CN105467059B (zh) * 2015-12-30 2017-10-24 云南理想药业有限公司 一种治疗血尿的中药组合物的质量检测方法
US20210085595A1 (en) 2017-07-26 2021-03-25 Clr Chemisches Laboratorium Dr. Kurt Richter Gmbh Topical herbal compositions
EP3434256A1 (fr) 2017-07-26 2019-01-30 CLR-Chemisches Laboratorium Dr. Kurt Richter GmbH Compositions d'herbes à usage topique
MX2020002884A (es) 2017-09-14 2020-10-05 Phoenix Biotechnology Inc Método y composición neuroprotectora mejorada para tratar afecciones neurológicas.
EP3681508A4 (fr) 2017-09-14 2021-05-19 Phoenix Biotechnology, Inc. Méthode et composition pour le traitement d'une infection virale
CN110680818A (zh) * 2018-07-06 2020-01-14 云南民族大学 丝石竹酸在制备镇痛药物中的应用
CN110089326A (zh) * 2019-03-08 2019-08-06 贵州民族大学 一种辅助剂及利用其提高马尾松抗病性能的方法
RU2020130238A (ru) 2020-03-31 2022-03-14 Феникс Байотекнолоджи, Инк. Способ и композиции для лечения коронавирусной инфекции
EP4009981B1 (fr) 2020-03-31 2023-08-16 Phoenix Biotechnology, Inc. Méthode et compositions pour le traitement d'une infection à coronavirus
RU2745401C1 (ru) * 2020-07-13 2021-03-24 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр "Институт биологии южных морей имени А.О. Ковалевского РАН" (ФИЦ ИнБЮМ) Способ индукции секреции биологически активных соединений у рапаны rapana venosa val.
CN111875662B (zh) * 2020-08-19 2022-08-16 中国人民解放军空军军医大学 一种美花铁线莲茎化学提取物的提取方法和应用
CN112245416A (zh) * 2020-11-17 2021-01-22 广西馨海药业科技有限公司 Pinnatifolone A在制备具有镇静、催眠作用药物中的应用及药物组合物
CN115843692B (zh) * 2022-12-29 2023-09-29 浙江省农业科学院 一种大花葱组织培养方法
CN116671440B (zh) * 2023-06-20 2024-05-03 江苏农林职业技术学院 一种丝瓜下胚轴离体再生方法及培养基配制
CN117653603B (zh) * 2023-10-16 2024-09-24 深圳市罗湖区人民医院 一种单萜香豆素衍生物纳米制剂及其制备方法和应用

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3070623A (en) 1957-07-16 1962-12-25 Biorex Laboratories Ltd Pharmacological compounds
US3070624A (en) 1960-03-04 1962-12-25 Biorex Laboratories Ltd Glycyrrhetinic acid dialkylaminoalkyl esters
GB1255098A (en) 1969-07-28 1971-11-24 Biorex Laboratories Ltd Derivatives of glycyrrhetinic acid
US3814766A (en) 1971-11-03 1974-06-04 Pfizer 11-deoxoglycyrrhetinic acid piperazides useful as antiulcer agents
US4196265A (en) 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US4452901A (en) 1980-03-20 1984-06-05 Ciba-Geigy Corporation Electrophoretically transferring electropherograms to nitrocellulose sheets for immuno-assays
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4526714A (en) 1982-12-13 1985-07-02 Cordis Europa N.V. Conjugates of anticoagulant and protein
US5221605A (en) 1984-10-31 1993-06-22 Igen, Inc. Luminescent metal chelate labels and means for detection
US5238808A (en) 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
US5310687A (en) 1984-10-31 1994-05-10 Igen, Inc. Luminescent metal chelate labels and means for detection
US5049388A (en) 1986-11-06 1991-09-17 Research Development Foundation Small particle aerosol liposome and liposome-drug combinations for medical use
US4975369A (en) 1988-04-21 1990-12-04 Eli Lilly And Company Recombinant and chimeric KS1/4 antibodies directed against a human adenocarcinoma antigen
US5183756A (en) 1988-08-19 1993-02-02 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibody (D612) having selective reactivity for gastrointestinal caricinomas and method for employing the same
AU651319B2 (en) 1989-07-27 1994-07-21 Univax Biologics Incorporated Lipid A analog/immunogenic carrier conjugates and the use thereof as vaccines
US5242813A (en) 1990-10-12 1993-09-07 The United States Of America As Represented By The Department Of Health And Human Services Mouse monoclonal antibodies specific for normal primate tissue, malignant human cultural cell lines human tumors
JPH0673084A (ja) 1992-08-27 1994-03-15 Shiratori Seiyaku Kk グリコシド及びこれを含有する抗肝炎剤
EP0679088B1 (fr) 1992-09-29 2002-07-10 Inhale Therapeutic Systems Liberation dans les poumons de fragments actifs d'hormone parathyroidienne
JP3222672B2 (ja) * 1993-12-16 2001-10-29 三井農林株式会社 タンパク質合成阻害剤
US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
DK0772619T4 (da) 1994-07-15 2011-02-21 Univ Iowa Res Found Immunmodulatoriske oligonukleotider
KR0164266B1 (ko) 1996-02-22 1999-01-15 오오니시 쿠니히로 인삼사포닌 장내세균 대사물 및 이를 유효성분으로하는 제암제제
US6214806B1 (en) 1997-02-28 2001-04-10 University Of Iowa Research Foundation Use of nucleic acids containing unmethylated CPC dinucleotide in the treatment of LPS-associated disorders
EP1005368B1 (fr) 1997-03-10 2009-09-02 Ottawa Hospital Research Institute Utilisation d'acides nucléiques contenat un dinucléotide CpG non-methylé combiné avec de l'aluminium en tant qu'adjuvants
US6339068B1 (en) 1997-05-20 2002-01-15 University Of Iowa Research Foundation Vectors and methods for immunization or therapeutic protocols
CA2330916C (fr) 1998-05-19 2011-04-05 Research Development Foundation Compositions de triterpene et leurs champ d'application

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US7105186B2 (en) 2006-09-12
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US6746696B2 (en) 2004-06-08
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US7670632B2 (en) 2010-03-02
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US7985435B2 (en) 2011-07-26
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