AU7527901A - Caspase inhibitors and uses thereof - Google Patents

Caspase inhibitors and uses thereof

Info

Publication number
AU7527901A
AU7527901A AU7527901A AU7527901A AU7527901A AU 7527901 A AU7527901 A AU 7527901A AU 7527901 A AU7527901 A AU 7527901A AU 7527901 A AU7527901 A AU 7527901A AU 7527901 A AU7527901 A AU 7527901A
Authority
AU
Australia
Prior art keywords
group
ring
hydrogen
aliphatic
caspase inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU7527901A
Other languages
English (en)
Inventor
Jean-Damien Charrier
Guy Brenchley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vertex Pharmaceuticals Inc
Original Assignee
Vertex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharmaceuticals Inc filed Critical Vertex Pharmaceuticals Inc
Publication of AU7527901A publication Critical patent/AU7527901A/xx
Pending legal-status Critical Current

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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
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AU7527901A 2000-06-07 2001-06-05 Caspase inhibitors and uses thereof Pending AU7527901A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20992900P 2000-06-07 2000-06-07
PCT/US2001/018243 WO2001094351A1 (en) 2000-06-07 2001-06-05 Caspase inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
AU7527901A true AU7527901A (en) 2001-12-17

Family

ID=22780912

Family Applications (2)

Application Number Title Priority Date Filing Date
AU7527901A Pending AU7527901A (en) 2000-06-07 2001-06-05 Caspase inhibitors and uses thereof
AU2001275279A Ceased AU2001275279B2 (en) 2000-06-07 2001-06-05 Caspase inhibitors and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2001275279A Ceased AU2001275279B2 (en) 2000-06-07 2001-06-05 Caspase inhibitors and uses thereof

Country Status (11)

Country Link
US (3) US7407964B2 (https=)
EP (1) EP1289993B9 (https=)
JP (1) JP2003535865A (https=)
KR (1) KR20030025235A (https=)
AT (1) ATE377010T1 (https=)
AU (2) AU7527901A (https=)
CA (1) CA2409015A1 (https=)
DE (1) DE60131160T2 (https=)
ES (1) ES2295171T3 (https=)
IL (1) IL152845A0 (https=)
WO (1) WO2001094351A1 (https=)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1176941C (zh) 1999-04-09 2004-11-24 西托维亚公司 Caspase抑制剂及其应用
EP1163208B1 (en) * 1999-08-06 2004-05-12 Vertex Pharmaceuticals Incorporated Caspase inhibitors and uses thereof
CN1235875C (zh) 1999-08-27 2006-01-11 西托维亚公司 取代的α－羟基酸天冬氨酸特异性半胱氨酸蛋白酶抑制剂及其用途
PE20011350A1 (es) 2000-05-19 2002-01-15 Vertex Pharma PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
EP1289993B9 (en) * 2000-06-07 2008-08-20 Vertex Pharmaceuticals Incorporated Caspase inhibitors and uses thereof
US7410956B2 (en) 2002-02-11 2008-08-12 Vertex Pharmaceuticals Incorporated Caspase inhibitor prodrugs
US7960398B2 (en) 2002-04-19 2011-06-14 Vertex Pharmaceuticals Incorporated Regulation of TNF-alpha
PE20040728A1 (es) 2002-06-28 2004-10-23 Vertex Pharma Inhibidores de caspasa
TW200500343A (en) * 2002-12-20 2005-01-01 Vertex Pharma Caspase inhibitors and uses thereof
EP1578748B1 (en) * 2002-12-27 2010-09-15 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Tetrahydro-4h-pyrido[1,2-a]pyrimidines and related compounds useful as hiv integrase inhibitors
JPWO2004073742A1 (ja) * 2003-02-24 2006-06-01 第一製薬株式会社 Ｂ型肝炎ウイルスｘ相互作用蛋白質の分解阻害剤
PE20050159A1 (es) 2003-05-27 2005-04-19 Vertex Pharma Derivados de acido 3-[2-(3-amino-2-oxo-2h-piridin-1-il)-acetilamino]-4-oxo-pentanoico como inhibidores de caspasa
IL158599A0 (en) * 2003-10-26 2004-05-12 Yeda Res & Dev Methods of modulating hematopoiesis
EP1718639A2 (en) 2004-02-27 2006-11-08 Vertex Pharmaceuticals Incorporated Caspase inhibitors and uses thereof
SG150547A1 (en) * 2004-03-12 2009-03-30 Vertex Pharma Processes and intermediates
MXPA06013256A (es) * 2004-05-15 2007-02-08 Vertex Pharma Tratamiento de crisis convulsivas utilizando inhibidores ice.
CA2567080A1 (en) 2004-05-27 2005-12-15 Vertex Pharmaceuticals Incorporated Ice inhibitors for the treatment of autoinflammatory diseases
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US20090023739A1 (en) 2009-01-22
ATE377010T1 (de) 2007-11-15
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US20110003824A1 (en) 2011-01-06
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