AU734312B2 - Administration of polypeptide growth factors following central nervous system ischemia or trauma - Google Patents
Administration of polypeptide growth factors following central nervous system ischemia or trauma Download PDFInfo
- Publication number
- AU734312B2 AU734312B2 AU25529/97A AU2552997A AU734312B2 AU 734312 B2 AU734312 B2 AU 734312B2 AU 25529/97 A AU25529/97 A AU 25529/97A AU 2552997 A AU2552997 A AU 2552997A AU 734312 B2 AU734312 B2 AU 734312B2
- Authority
- AU
- Australia
- Prior art keywords
- administration
- growth factor
- injury
- animals
- bfgf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Control Of Electric Motors In General (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Control Of Motors That Do Not Use Commutators (AREA)
- Protection Of Generators And Motors (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62044496A | 1996-03-22 | 1996-03-22 | |
| US08/620444 | 1996-03-22 | ||
| PCT/US1997/005071 WO1997034618A1 (en) | 1996-03-22 | 1997-03-21 | Administration of polypeptide growth factors following central nervous system ischemia or trauma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2552997A AU2552997A (en) | 1997-10-10 |
| AU734312B2 true AU734312B2 (en) | 2001-06-07 |
Family
ID=24485972
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU25529/97A Ceased AU734312B2 (en) | 1996-03-22 | 1997-03-21 | Administration of polypeptide growth factors following central nervous system ischemia or trauma |
| AU25823/97A Ceased AU725341B2 (en) | 1996-03-22 | 1997-03-21 | Methods for enhancing functional recovery following central nervous system ischemia or trauma |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU25823/97A Ceased AU725341B2 (en) | 1996-03-22 | 1997-03-21 | Methods for enhancing functional recovery following central nervous system ischemia or trauma |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US6407060B1 (enExample) |
| EP (3) | EP1364655B1 (enExample) |
| JP (2) | JP2000507939A (enExample) |
| KR (1) | KR20000064752A (enExample) |
| CN (1) | CN1181885C (enExample) |
| AT (2) | ATE493141T1 (enExample) |
| AU (2) | AU734312B2 (enExample) |
| CA (2) | CA2249368A1 (enExample) |
| DE (2) | DE69740089D1 (enExample) |
| ES (1) | ES2201287T5 (enExample) |
| WO (2) | WO1997034626A1 (enExample) |
Families Citing this family (66)
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| ATE278414T1 (de) | 1997-05-05 | 2004-10-15 | Curis Inc | Therapien zur behandlung von akutem nierenversagen |
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| US20030170213A1 (en) * | 1998-01-23 | 2003-09-11 | Marc F. Charette | Methods and compositions for enhancing cognitive function using morphogenic proteins |
| US7147839B2 (en) | 1998-05-29 | 2006-12-12 | Curis, Inc. | Methods for evaluating tissue morphogenesis and activity |
| DE19837230A1 (de) * | 1998-08-17 | 2000-03-09 | Jean Krutmann | Neurotrophin-4 zur Behandlung von Tumoren neuroektodermalen Ursprungs |
| US6727224B1 (en) | 1999-02-01 | 2004-04-27 | Genetics Institute, Llc. | Methods and compositions for healing and repair of articular cartilage |
| MXPA02001719A (es) * | 1999-08-18 | 2003-09-25 | Childrens Medical Center | METODOS, COMPOSICIONES Y EQUIPOS PARA PROMOVER LA RECUPERACION DEL DAnO AL SISTEMA NERVIOSO CENTRAL. |
| US6749850B1 (en) | 1999-08-18 | 2004-06-15 | The General Hospital Corporation | Methods, compositions and kits for promoting recovery from damage to the central nervous system |
| ATE271886T1 (de) | 1999-10-15 | 2004-08-15 | Inst Genetics Llc | Hyaluronsäure enthaltende zusammensetzungen zur abgabe osteogener proteine |
| US7060676B2 (en) * | 1999-12-20 | 2006-06-13 | Trustees Of Tufts College | T. cruzi-derived neurotrophic agents and methods of use therefor |
| US7541184B2 (en) | 2000-02-24 | 2009-06-02 | Invitrogen Corporation | Activation and expansion of cells |
| US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| JP2003534385A (ja) | 2000-06-01 | 2003-11-18 | チルドレンズ メディカル センター コーポレーション | 被験者の神経に有益な効果をもたらす方法および組成物 |
| US6855690B2 (en) | 2000-06-01 | 2005-02-15 | Children's Medical Center Corporation | Methods and compositions for treating ocular disorders |
| TW200526779A (en) | 2001-02-08 | 2005-08-16 | Wyeth Corp | Modified and stabilized GDF propeptides and uses thereof |
| US7700819B2 (en) | 2001-02-16 | 2010-04-20 | Kci Licensing, Inc. | Biocompatible wound dressing |
| US7763769B2 (en) | 2001-02-16 | 2010-07-27 | Kci Licensing, Inc. | Biocompatible wound dressing |
| US20030022210A1 (en) * | 2001-06-01 | 2003-01-30 | Mark Bonyhadi | T cell induced tissue repair and regeneration |
| DE60226321T2 (de) | 2001-06-01 | 2009-07-09 | Wyeth | Zusammensetzungen für die systemische verabreichung von sequenzen, die für knochenmorphogenese-proteinen kodieren |
| TWI267378B (en) | 2001-06-08 | 2006-12-01 | Wyeth Corp | Calcium phosphate delivery vehicles for osteoinductive proteins |
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| WO2006009836A2 (en) | 2004-06-17 | 2006-01-26 | Thrasos Therapeutics, Inc. | Tdf-related compounds and analogs thereof |
| EP2453024B1 (en) | 2004-06-21 | 2017-12-06 | The Board of Trustees of The Leland Stanford Junior University | Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder |
| WO2006012365A2 (en) * | 2004-07-20 | 2006-02-02 | University Of Maryland | Protease inhibitor |
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| US8697139B2 (en) | 2004-09-21 | 2014-04-15 | Frank M. Phillips | Method of intervertebral disc treatment using articular chondrocyte cells |
| GB0425625D0 (en) * | 2004-11-22 | 2004-12-22 | Royal College Of Surgeons Ie | Treatment of disease |
| HUE026634T2 (en) | 2005-09-20 | 2016-07-28 | Thrasos Innovation Inc | TDF-related compounds and analogues thereof |
| DK2564864T3 (en) | 2005-11-12 | 2015-04-07 | Trustees Of The Leland Board Of | FGF-2 related methods for the diagnosis and treatment of depression |
| AU2007234612B2 (en) * | 2006-12-14 | 2013-06-27 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein stabilization formulations |
| HRP20120698T1 (hr) * | 2007-01-25 | 2013-09-30 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh | Uporaba dgf-5 za poboljšanje ili održavanje izgleda kože |
| US7678764B2 (en) | 2007-06-29 | 2010-03-16 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein formulations for use at elevated temperatures |
| CA2695697A1 (en) | 2007-08-07 | 2009-02-12 | Advanced Technologies And Regenerative Medicine, Llc | Protein formulations comprising gdf-5 in aqueous acidic solution |
| BRPI0911048A2 (pt) * | 2008-04-14 | 2015-12-29 | Atrm Llc | formulações líquidas tamponadas de gdf-5 |
| SG173634A1 (en) * | 2009-02-12 | 2011-09-29 | Stryker Corp | COMPOSITIONS AND METHODS FOR MINIMALLY-INVASIVE SYSTEMIC DELIVERY OF PROTEINS INCLUDING TGF-ß SUPERFAMILY MEMBERS |
| EP2396025A2 (en) * | 2009-02-12 | 2011-12-21 | Stryker Corporation | Peripheral administration of proteins including tgf-beta superfamily members for systemic treatment of disorders and disease |
| US8828937B2 (en) | 2009-03-12 | 2014-09-09 | Haase Investments Ug | Bone morphogenetic protein 2 (BMP2) variants with reduced BMP antagonist sensitivity |
| WO2010144696A1 (en) | 2009-06-11 | 2010-12-16 | Burnham Institute For Medical Research | Directed differentiation of stem cells |
| EP2352750B1 (en) | 2009-09-17 | 2012-06-13 | Stryker Corporation | Buffers for controlling the ph of bone morphogenetic proteins |
| EP2516456A1 (en) | 2009-12-22 | 2012-10-31 | Stryker Corporation | Bmp-7 variants with reduced immunogenicity |
| CN101822815A (zh) * | 2010-04-29 | 2010-09-08 | 广东八加一医药有限公司 | 系列多肽小分子在制备防治缺血性脑血管疾病药物中的应用 |
| US9688735B2 (en) | 2010-08-20 | 2017-06-27 | Wyeth Llc | Designer osteogenic proteins |
| WO2012023113A2 (en) | 2010-08-20 | 2012-02-23 | Wyeth Llc | Designer osteogenic proteins |
| CA2829006A1 (en) | 2011-03-04 | 2012-09-13 | The Regents Of The University Of California | Locally released growth factors to mediate motor recovery after stroke |
| KR101274930B1 (ko) * | 2011-06-03 | 2013-06-17 | 전남대학교산학협력단 | 골 형성 또는 혈관신생 촉진용 펩타이드 bfp 4 및 이의 용도 |
| BR112014001268A2 (pt) * | 2011-07-19 | 2017-02-21 | Thrasos Innovation Inc | peptídeos antifibróticos e seu uso em métodos para tratamento de doenças e distúrbios caracterizados por fibrose |
| EP2784083A1 (en) | 2013-03-28 | 2014-10-01 | Charité - Universitätsmedizin Berlin | Bone Morphogenetic Protein (BMP) variants with highly reduced antagonist sensitivity and enhanced specific biological activity |
| EP2981822B1 (en) | 2013-05-06 | 2020-09-02 | Scholar Rock, Inc. | Compositions and methods for growth factor modulation |
| WO2014201143A1 (en) * | 2013-06-11 | 2014-12-18 | President And Fellows Of Harvard College | Methods and compositions for increasing neurogenesis and angiogenesis |
| EP3543339A1 (en) | 2015-02-13 | 2019-09-25 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| CN116115629A (zh) | 2016-08-17 | 2023-05-16 | 菲克特生物科学股份有限公司 | 核酸产品及其施用方法 |
| BR112021000018A2 (pt) * | 2018-07-03 | 2021-07-06 | Venturis Therapeutics Inc | composições e métodos para tratamento de acidente vascular cerebral |
| CN115190886A (zh) * | 2020-02-20 | 2022-10-14 | 马斯特里赫特大学 | 循环bmp10(骨形态发生蛋白10)的检测方法 |
| WO2021236824A1 (en) * | 2020-05-19 | 2021-11-25 | Elevian, Inc. | Methods and compositions for treating stroke |
| WO2024259004A1 (en) * | 2023-06-13 | 2024-12-19 | Bedford Research Foundation | Systems and methods of cell transport at ambient temperature |
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-
1997
- 1997-03-21 ES ES97917532T patent/ES2201287T5/es not_active Expired - Lifetime
- 1997-03-21 AT AT03010945T patent/ATE493141T1/de not_active IP Right Cessation
- 1997-03-21 US US08/828,281 patent/US6407060B1/en not_active Expired - Lifetime
- 1997-03-21 WO PCT/US1997/004177 patent/WO1997034626A1/en not_active Ceased
- 1997-03-21 DE DE69740089T patent/DE69740089D1/de not_active Expired - Lifetime
- 1997-03-21 KR KR1019980707507A patent/KR20000064752A/ko not_active Ceased
- 1997-03-21 CA CA002249368A patent/CA2249368A1/en not_active Abandoned
- 1997-03-21 JP JP9533791A patent/JP2000507939A/ja not_active Withdrawn
- 1997-03-21 US US08/822,455 patent/US6214796B1/en not_active Expired - Fee Related
- 1997-03-21 EP EP03010945A patent/EP1364655B1/en not_active Expired - Lifetime
- 1997-03-21 CN CNB97194749XA patent/CN1181885C/zh not_active Expired - Fee Related
- 1997-03-21 EP EP97917532A patent/EP0894004B2/en not_active Expired - Lifetime
- 1997-03-21 DE DE69723429T patent/DE69723429T3/de not_active Expired - Lifetime
- 1997-03-21 WO PCT/US1997/005071 patent/WO1997034618A1/en not_active Ceased
- 1997-03-21 EP EP97917091A patent/EP0904093A4/en not_active Withdrawn
- 1997-03-21 AT AT97917532T patent/ATE244574T1/de not_active IP Right Cessation
- 1997-03-21 CA CA2249596A patent/CA2249596C/en not_active Expired - Fee Related
- 1997-03-21 AU AU25529/97A patent/AU734312B2/en not_active Ceased
- 1997-03-21 JP JP53358397A patent/JP4847634B2/ja not_active Expired - Fee Related
- 1997-03-21 AU AU25823/97A patent/AU725341B2/en not_active Ceased
-
2001
- 2001-04-10 US US09/833,096 patent/US20010039261A1/en not_active Abandoned
-
2002
- 2002-02-01 US US10/062,370 patent/US20030022830A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4994559A (en) * | 1985-12-17 | 1991-02-19 | Synergen, Inc. | Human basic fibroblast growth factor |
| EP0501445A1 (en) * | 1991-02-27 | 1992-09-02 | Yeda Research And Development Co. Ltd. | Pharmaceutical composition comprising interleukin-2 |
| WO1993009802A2 (en) * | 1991-11-22 | 1993-05-27 | Genentech, Inc. | Tgf-beta to improve neural outcome |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2582397A (en) | 1997-10-10 |
| AU725341B2 (en) | 2000-10-12 |
| AU2552997A (en) | 1997-10-10 |
| US6214796B1 (en) | 2001-04-10 |
| EP1364655B1 (en) | 2010-12-29 |
| EP0894004A1 (en) | 1999-02-03 |
| CA2249596A1 (en) | 1997-09-25 |
| CA2249596C (en) | 2011-11-08 |
| DE69740089D1 (de) | 2011-02-10 |
| ATE493141T1 (de) | 2011-01-15 |
| DE69723429T3 (de) | 2007-09-20 |
| DE69723429T2 (de) | 2004-04-22 |
| WO1997034626A1 (en) | 1997-09-25 |
| EP0894004B1 (en) | 2003-07-09 |
| EP0904093A1 (en) | 1999-03-31 |
| US6407060B1 (en) | 2002-06-18 |
| WO1997034618A1 (en) | 1997-09-25 |
| CN1219133A (zh) | 1999-06-09 |
| CA2249368A1 (en) | 1997-09-25 |
| EP1364655A1 (en) | 2003-11-26 |
| DE69723429D1 (de) | 2003-08-14 |
| CN1181885C (zh) | 2004-12-29 |
| EP0904093A4 (en) | 2004-11-17 |
| US20010039261A1 (en) | 2001-11-08 |
| EP0894004B2 (en) | 2007-02-21 |
| KR20000064752A (ko) | 2000-11-06 |
| US20030022830A1 (en) | 2003-01-30 |
| JP2000506894A (ja) | 2000-06-06 |
| ES2201287T3 (es) | 2004-03-16 |
| JP4847634B2 (ja) | 2011-12-28 |
| JP2000507939A (ja) | 2000-06-27 |
| ES2201287T5 (es) | 2007-10-16 |
| ATE244574T1 (de) | 2003-07-15 |
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| Date | Code | Title | Description |
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| FGA | Letters patent sealed or granted (standard patent) |