AU680496B2 - Novel bisoxadiazolidine derivative - Google Patents

Novel bisoxadiazolidine derivative Download PDF

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Publication number
AU680496B2
AU680496B2 AU65823/94A AU6582394A AU680496B2 AU 680496 B2 AU680496 B2 AU 680496B2 AU 65823/94 A AU65823/94 A AU 65823/94A AU 6582394 A AU6582394 A AU 6582394A AU 680496 B2 AU680496 B2 AU 680496B2
Authority
AU
Australia
Prior art keywords
group
bis
magnetic resonance
nuclear magnetic
internal standard
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU65823/94A
Other languages
English (en)
Other versions
AU6582394A (en
Inventor
Jun Irie
Reiko Koike
Toru Kontani
Kyoichi Maeno
Tatsuya Maruyama
Kunihiro Niigata
Osamu Noshiro
Kenichi Onda
Akiyoshi Shimaya
Takayuki Suzuki
Takumi Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of AU6582394A publication Critical patent/AU6582394A/en
Application granted granted Critical
Publication of AU680496B2 publication Critical patent/AU680496B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU65823/94A 1993-04-30 1994-04-26 Novel bisoxadiazolidine derivative Ceased AU680496B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP12789893 1993-04-30
JP5-127898 1993-04-30
JP5-350209 1993-12-29
JP35020993 1993-12-29
PCT/JP1994/000696 WO1994025448A1 (fr) 1993-04-30 1994-04-26 Nouveau derive de bisoxadiazolidine

Publications (2)

Publication Number Publication Date
AU6582394A AU6582394A (en) 1994-11-21
AU680496B2 true AU680496B2 (en) 1997-07-31

Family

ID=26463731

Family Applications (1)

Application Number Title Priority Date Filing Date
AU65823/94A Ceased AU680496B2 (en) 1993-04-30 1994-04-26 Novel bisoxadiazolidine derivative

Country Status (14)

Country Link
US (1) US5643931A (enExample)
EP (1) EP0696585B1 (enExample)
CN (1) CN1045005C (enExample)
AT (1) ATE174593T1 (enExample)
AU (1) AU680496B2 (enExample)
CA (1) CA2160989A1 (enExample)
DE (1) DE69415314T2 (enExample)
DK (1) DK0696585T3 (enExample)
ES (1) ES2129123T3 (enExample)
GR (1) GR3029428T3 (enExample)
HU (1) HUT73431A (enExample)
RU (1) RU2135487C1 (enExample)
TW (1) TW401418B (enExample)
WO (1) WO1994025448A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1244542C (zh) * 1996-12-24 2006-03-08 中外制药株式会社 具有nos抑制作用的芳香族胺衍生物
US6221914B1 (en) 1997-11-10 2001-04-24 Array Biopharma Inc. Sulfonamide bridging compounds that inhibit tryptase activity
US6534037B1 (en) 1998-01-21 2003-03-18 Neorx Corporation Non-steroidal compounds for steroid receptors and uses relating thereto
DE60123665T2 (de) * 2000-12-26 2007-08-16 Sankyo Co., Ltd. Medizinische zusammensetzungen mit diuretischem und die insulinresistenz verbesserndem mittel
US20050119314A1 (en) * 2002-04-05 2005-06-02 Sankyo Company, Limited Pharmaceutical composition comprising an ACAT inhibitor and an insulin resistance reducing agent
US7816385B2 (en) 2002-12-20 2010-10-19 High Point Pharmaceuticals, Llc Dimeric dicarboxylic acid derivatives, their preparation and use
US7141592B2 (en) * 2003-09-25 2006-11-28 Wyeth Substituted oxadiazolidinediones
US7608639B2 (en) 2003-10-14 2009-10-27 Eli Lilly And Company Phenoxyether derivatives as PPAR modulators
TW200815377A (en) * 2006-04-24 2008-04-01 Astellas Pharma Inc Oxadiazolidinedione compound
TW200932219A (en) * 2007-10-24 2009-08-01 Astellas Pharma Inc Oxadiazolidinedione compound
EP2332528A1 (de) * 2009-12-14 2011-06-15 Grünenthal GmbH Substituierte aromatische Dicarbonsäureamide als Arzneimittel
KR101661825B1 (ko) * 2011-08-03 2016-09-30 내셔널 타이완 유니버시티 Ｓｒｃ 상동성-2 함유 단백질 티로신 포스파타제-1의 작용물질 및 그를 사용한 치료방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4598153A (en) * 1984-12-19 1986-07-01 The United States Of America As Represented By The Department Of Health And Human Services Metaphit, a specific acylating agent for the [3 H] phencyclidine
CA2087437A1 (en) * 1990-08-23 1992-02-24 Steven W. Goldstein Hypoglycemic hydroxyurea derivatives
JP3176063B2 (ja) * 1991-04-17 2001-06-11 ファルマシア・アンド・アップジョン・カンパニー 新規中枢神経作用性置換フェニルアザシクロアルカン類
US5508296A (en) * 1991-07-30 1996-04-16 Yamanouchi Pharmaceutical Co., Ltd. Bisheterocyclic derivative or salt thereof
WO1993009106A1 (fr) * 1991-10-28 1993-05-13 Tsentr Po Khimii Lekarstvennykh Sredstv Derives de 5-phenoxymethyle-1,2,4-oxadiazole, leur sels, procede d'obtention et preparation pharmaceutique a base de ceux-ci presentant des proprietes antihypertensives, antiangineuses, antiarrhythmiques et antiglaucomatomeuses
US5420146A (en) * 1994-05-10 1995-05-30 American Home Products Corporation Di-oxadiazolidine derivatives as antihyperglycemic agents
JPH09303021A (ja) * 1996-05-17 1997-11-25 Matsushita Electric Works Ltd 近接型ワイヤレス電気錠制御システム

Also Published As

Publication number Publication date
US5643931A (en) 1997-07-01
EP0696585A1 (en) 1996-02-14
CN1122133A (zh) 1996-05-08
DE69415314T2 (de) 1999-05-20
DK0696585T3 (da) 1999-08-23
ES2129123T3 (es) 1999-06-01
WO1994025448A1 (fr) 1994-11-10
EP0696585B1 (en) 1998-12-16
CN1045005C (zh) 1999-09-08
DE69415314D1 (de) 1999-01-28
HU9503090D0 (en) 1995-12-28
AU6582394A (en) 1994-11-21
HUT73431A (en) 1996-07-29
ATE174593T1 (de) 1999-01-15
RU2135487C1 (ru) 1999-08-27
EP0696585A4 (enExample) 1996-03-27
GR3029428T3 (en) 1999-05-28
TW401418B (en) 2000-08-11
CA2160989A1 (en) 1994-11-10

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired