AU643511B2 - Bacterial vectors - Google Patents

Bacterial vectors Download PDF

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Publication number
AU643511B2
AU643511B2 AU73558/91A AU7355891A AU643511B2 AU 643511 B2 AU643511 B2 AU 643511B2 AU 73558/91 A AU73558/91 A AU 73558/91A AU 7355891 A AU7355891 A AU 7355891A AU 643511 B2 AU643511 B2 AU 643511B2
Authority
AU
Australia
Prior art keywords
plasmid
lactis
msp
hybrid vector
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU73558/91A
Other languages
English (en)
Other versions
AU7355891A (en
Inventor
Albert Schmitz
Bruno Suri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU7355891A publication Critical patent/AU7355891A/en
Application granted granted Critical
Publication of AU643511B2 publication Critical patent/AU643511B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/853Lactobacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
AU73558/91A 1990-03-22 1991-03-15 Bacterial vectors Ceased AU643511B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9006400 1990-03-22
GB909006400A GB9006400D0 (en) 1990-03-22 1990-03-22 Bacterial vectors

Publications (2)

Publication Number Publication Date
AU7355891A AU7355891A (en) 1991-10-03
AU643511B2 true AU643511B2 (en) 1993-11-18

Family

ID=10673033

Family Applications (1)

Application Number Title Priority Date Filing Date
AU73558/91A Ceased AU643511B2 (en) 1990-03-22 1991-03-15 Bacterial vectors

Country Status (22)

Country Link
US (1) US5559007A (enrdf_load_stackoverflow)
EP (1) EP0449770B1 (enrdf_load_stackoverflow)
JP (1) JPH04211384A (enrdf_load_stackoverflow)
KR (1) KR910016930A (enrdf_load_stackoverflow)
AR (1) AR245504A1 (enrdf_load_stackoverflow)
AT (1) ATE174055T1 (enrdf_load_stackoverflow)
AU (1) AU643511B2 (enrdf_load_stackoverflow)
BR (1) BR9101137A (enrdf_load_stackoverflow)
CA (1) CA2038706A1 (enrdf_load_stackoverflow)
DE (1) DE69130544T2 (enrdf_load_stackoverflow)
DK (1) DK0449770T3 (enrdf_load_stackoverflow)
ES (1) ES2125864T3 (enrdf_load_stackoverflow)
FI (1) FI911367A7 (enrdf_load_stackoverflow)
GB (1) GB9006400D0 (enrdf_load_stackoverflow)
HU (1) HUT57263A (enrdf_load_stackoverflow)
IE (1) IE910948A1 (enrdf_load_stackoverflow)
MX (1) MX25027A (enrdf_load_stackoverflow)
NO (1) NO911138L (enrdf_load_stackoverflow)
NZ (1) NZ237506A (enrdf_load_stackoverflow)
PT (1) PT97081B (enrdf_load_stackoverflow)
TW (1) TW213488B (enrdf_load_stackoverflow)
ZA (1) ZA912114B (enrdf_load_stackoverflow)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286361A (en) * 1992-10-19 1994-02-15 Regents Of The University Of California Magnetically attached sputter targets
WO1996032486A1 (en) * 1995-04-11 1996-10-17 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Method for the construction of vectors for lactic acid bacteria like lactobacillus such that the bacteria can efficiently express, secrete and display proteins at the surface
GB9521568D0 (en) * 1995-10-20 1995-12-20 Lynxvale Ltd Delivery of biologically active polypeptides
US6133023A (en) * 1996-09-06 2000-10-17 Bioteknologisk Institut Lactic acid bacterial regulatable expression system
EP1239032A1 (en) * 2001-03-02 2002-09-11 Société des Produits Nestlé S.A. Lactic acid bacteria as agents for treating and preventing allergy
US7780961B2 (en) 2001-05-03 2010-08-24 Actogenix N.V. Self-containing Lactococcus strain
CA2489930A1 (en) 2002-06-19 2003-12-31 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Methods and means to promote gut absorption
EP1560935A2 (en) * 2002-11-15 2005-08-10 VIB vzw Self-containing lactobacillus strain
CA2631598C (en) 2005-11-29 2017-06-27 Actogenix Nv Induction of mucosal tolerance to antigens
ES2595729T3 (es) 2007-01-12 2017-01-03 Intrexon Actobiotics Nv Promotores de Lactococcus y usos de los mismos
BRPI0807857A2 (pt) 2007-01-25 2014-05-27 Actogenix Nv Tratamento de doença imune por meio de distribuição através da mucosa de antígenos.
JP5126879B2 (ja) * 2007-07-13 2013-01-23 独立行政法人海洋研究開発機構 新規dna断片およびそれを含む組換えベクター、それらによって形質転換された形質転換体、ならびにそれらの利用
WO2010034844A1 (en) 2008-09-29 2010-04-01 Actogenix N.V. Reduced colonization of microbes at the mucosa
WO2010124855A1 (en) 2009-04-30 2010-11-04 Actogenix Nv Cryoprotectants for freeze drying of lactic acid bacteria
EP2275527A1 (en) 2009-07-17 2011-01-19 ActoGeniX NV Animal component-free culture medium for bacterial fermentation
US20120183503A1 (en) 2009-09-29 2012-07-19 Actogenix N.V. Lactobacillus and streptococcus promoters and uses thereof
JP2013530187A (ja) 2010-06-17 2013-07-25 ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンティッド バイ ザ シークレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ 炎症性疾患を治療するための組成物及び方法。
RU2644346C2 (ru) 2011-06-01 2018-02-08 Интрексон Актобиотикс Н.В. Система полицистронной экспрессии для бактерий
US9458467B2 (en) 2011-09-23 2016-10-04 Intrexon Actobiotics Nv Modified gram positive bacteria and uses thereof
JP6329903B2 (ja) 2011-09-23 2018-05-23 イントレクソン・アクトバイオテイクス・エヌブイIntrexon Actobiotics NV 改変されたグラム陽性菌及びその使用
EP3919065B9 (en) 2016-01-14 2024-01-24 Intrexon Actobiotics NV Compositions and methods for the treatment of type 1 diabetes
US20200095566A1 (en) * 2017-03-22 2020-03-26 Agency For Science, Technology And Research Protein Expression Construct and Methods Thereof
CN116144690A (zh) * 2022-08-23 2023-05-23 江西省科学院微生物研究所(江西省流域生态研究所) 一种大肠杆菌与乳酸菌的穿梭载体pDXA及构建方法与应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0455280A1 (en) * 1990-03-30 1991-11-06 Nederlands Instituut Voor Zuivelonderzoek DNA fragment from lactococcus lactis and fusion proteins thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8400687A (nl) 1984-03-02 1985-10-01 Unilever Nv Recombinant plasmiden; recombinant plasmiden bevattende bacterien; werkwijze voor het bereiden of vervaardigen van een zuivelproduct; werkwijze voor het bereiden van een eiwit.
DE3583361D1 (de) 1984-06-14 1991-08-08 Ucp Gen Pharma Ag Verfahren zur herstellung von thrombin-inhibitoren.
NL8503316A (nl) * 1985-11-29 1987-06-16 Stichting Nl I Zuivelonderzoek Werkwijze voor het bereiden van proteinen met behulp van gastheer-organismen, in het bijzonder melkzuurbacterien, welke recombinant dna-plasmiden met een hoge replicon-aktiviteit en een hoge promotor-aktiviteit voor het betreffende proteine-coderende gen bevatten, de van dergelijke recombinant dna-plasmiden voorziene gastheerorganismen, de recombinant dna-plasmiden zelve, de replicon-aktiviteit en promotor-aktiviteit coderende dna-fragmenten, alsmede de verkregen proteinen.
EP0316677A3 (en) 1987-11-13 1990-04-25 Miles Inc. Method for cloning in lactic acid bacteria

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0455280A1 (en) * 1990-03-30 1991-11-06 Nederlands Instituut Voor Zuivelonderzoek DNA fragment from lactococcus lactis and fusion proteins thereof

Also Published As

Publication number Publication date
ATE174055T1 (de) 1998-12-15
AR245504A1 (es) 1994-01-31
BR9101137A (pt) 1991-11-05
US5559007A (en) 1996-09-24
DK0449770T3 (da) 1999-06-23
ZA912114B (en) 1992-01-29
CA2038706A1 (en) 1991-09-23
NO911138L (no) 1991-09-23
FI911367L (fi) 1991-09-23
TW213488B (enrdf_load_stackoverflow) 1993-09-21
FI911367A0 (fi) 1991-03-20
IE910948A1 (en) 1991-09-25
MX25027A (es) 1993-12-01
PT97081A (pt) 1991-11-29
AU7355891A (en) 1991-10-03
HUT57263A (en) 1991-11-28
DE69130544T2 (de) 1999-04-29
DE69130544D1 (de) 1999-01-14
NZ237506A (en) 1992-12-23
ES2125864T3 (es) 1999-03-16
HU910958D0 (en) 1991-10-28
EP0449770A3 (en) 1992-07-01
JPH04211384A (ja) 1992-08-03
EP0449770B1 (en) 1998-12-02
NO911138D0 (no) 1991-03-21
KR910016930A (ko) 1991-11-05
GB9006400D0 (en) 1990-05-23
EP0449770A2 (en) 1991-10-02
FI911367A7 (fi) 1991-09-23
PT97081B (pt) 1998-07-31

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