AU638613B2 - Process for producing azacycloalkane derivative - Google Patents

Process for producing azacycloalkane derivative Download PDF

Info

Publication number
AU638613B2
AU638613B2 AU87624/91A AU8762491A AU638613B2 AU 638613 B2 AU638613 B2 AU 638613B2 AU 87624/91 A AU87624/91 A AU 87624/91A AU 8762491 A AU8762491 A AU 8762491A AU 638613 B2 AU638613 B2 AU 638613B2
Authority
AU
Australia
Prior art keywords
water
organic solvent
reducing agent
integer
process according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU87624/91A
Other languages
English (en)
Other versions
AU8762491A (en
Inventor
Terumi Hachiya
Hisataka Inoue
Kanji Noda
Masaru Saita
Shigenori Yahiro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Publication of AU8762491A publication Critical patent/AU8762491A/en
Application granted granted Critical
Publication of AU638613B2 publication Critical patent/AU638613B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C07D223/10—Oxygen atoms attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Catalysts (AREA)
  • Steroid Compounds (AREA)
AU87624/91A 1990-10-31 1991-10-23 Process for producing azacycloalkane derivative Ceased AU638613B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2291876A JPH07595B2 (ja) 1990-10-31 1990-10-31 アザシクロアルカン誘導体の製造方法
JP2-291876 1990-10-31

Publications (2)

Publication Number Publication Date
AU8762491A AU8762491A (en) 1992-05-26
AU638613B2 true AU638613B2 (en) 1993-07-01

Family

ID=17774584

Family Applications (1)

Application Number Title Priority Date Filing Date
AU87624/91A Ceased AU638613B2 (en) 1990-10-31 1991-10-23 Process for producing azacycloalkane derivative

Country Status (11)

Country Link
US (1) US5371238A (enExample)
EP (1) EP0555483B1 (enExample)
JP (1) JPH07595B2 (enExample)
KR (1) KR960014349B1 (enExample)
CN (1) CN1026320C (enExample)
AT (1) ATE199372T1 (enExample)
AU (1) AU638613B2 (enExample)
CA (1) CA2089880C (enExample)
DE (1) DE69132547T2 (enExample)
ES (1) ES2154632T3 (enExample)
WO (1) WO1992007827A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121135627B (zh) * 2025-09-09 2026-06-23 广东湛江海洋医药研究院 一种β’-硫代-α,β-不饱和γ-内酰胺衍生物及其制备方法与应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7020787A (en) * 1986-04-08 1987-11-09 Hisamitsu Pharmaceutical Co., Inc. Azacycloalkane derivatives, absorption promoters containing the derivatives as the effective ingredient and external preparations containing the absorption promoters

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6330466A (ja) * 1986-07-24 1988-02-09 Hisamitsu Pharmaceut Co Inc アザシクロアルカン化合物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7020787A (en) * 1986-04-08 1987-11-09 Hisamitsu Pharmaceutical Co., Inc. Azacycloalkane derivatives, absorption promoters containing the derivatives as the effective ingredient and external preparations containing the absorption promoters

Also Published As

Publication number Publication date
CA2089880A1 (en) 1992-05-01
US5371238A (en) 1994-12-06
ATE199372T1 (de) 2001-03-15
JPH04169571A (ja) 1992-06-17
EP0555483A1 (en) 1993-08-18
EP0555483B1 (en) 2001-02-28
KR930702294A (ko) 1993-09-08
CA2089880C (en) 2002-01-29
KR960014349B1 (ko) 1996-10-15
DE69132547T2 (de) 2001-06-13
AU8762491A (en) 1992-05-26
CN1026320C (zh) 1994-10-26
EP0555483A4 (enExample) 1994-03-23
WO1992007827A1 (fr) 1992-05-14
JPH07595B2 (ja) 1995-01-11
DE69132547D1 (de) 2001-04-05
ES2154632T3 (es) 2001-04-16
CN1061592A (zh) 1992-06-03

Similar Documents

Publication Publication Date Title
US4156084A (en) Certain dimers of tetrahydropyridine-2-carboxylic acids or pyrroline-2-carboxylic acids and derivatives thereof
DK157487B (da) Analogifremgangsmaade til fremstilling af prolinderivater.
US4705867A (en) Process for the production of 1,2-dithiolan-3-pentanoic acid (thioctic acid) and intermediate compounds therefor
FI67378B (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tiazolidin- och tiazanderivat
US4332725A (en) Process for the preparation of 1-[3-mercapto-(2S)-methylpropionyl]-pyrrolidine-(2S)-carboxylic acid
US4507500A (en) Process for producing 2-mercaptoethylamine hydrohalides
US5371238A (en) Process for producing azacycloalkane derivatives
MXPA06006709A (es) Proceso para sintetizar disulfuros.
ES2181886T3 (es) Procedimientos de preparacion de compuestos ciclicos.
IL40088A (en) Tri-iodinated n-methyldicarboxylic acid anilides and process for their manufacture
IE47971B1 (en) Halogen substituted mercaptoacylamino acid
KR830007484A (ko) 신규 신나모일-신나민산 유도체의 제조방법
KR960029319A (ko) 4-아미노벤조일구아니딘 유도체
US3132154A (en) Production of ascorbic acid esters
KR100356075B1 (ko) 메르캅토카르복실산에스테르의합성방법
US3682965A (en) Sulfur-containing pyrrolidines
HUT68036A (en) Cyclohexane derivatives, pharmaceutical compositons containing same and process for their production
EP0224592B1 (en) P-hydroxybenzoic acid derivatives
GB2118553A (en) Thiamorpholinones
FI68611C (fi) Foerfarande foer framstaellning av en trans-4-aminometylcyklohexankarboxylsyraester
AT394718B (de) Verfahren zur herstellung von neuen substituierten thiamorpholinonderivaten und deren sulfoxiden
EP4139281A1 (en) Sulfur extrusion from disulfides by carbenes
SE426698B (sv) Nya terapeutiskt aktiva derivat av 3,4-dehydroprolin