AU637657B2 - Co-polymer production - Google Patents
Co-polymer production Download PDFInfo
- Publication number
- AU637657B2 AU637657B2 AU67827/90A AU6782790A AU637657B2 AU 637657 B2 AU637657 B2 AU 637657B2 AU 67827/90 A AU67827/90 A AU 67827/90A AU 6782790 A AU6782790 A AU 6782790A AU 637657 B2 AU637657 B2 AU 637657B2
- Authority
- AU
- Australia
- Prior art keywords
- component
- bacterium
- growth
- monomer units
- substrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- 229920001577 copolymer Polymers 0.000 title claims abstract description 57
- 238000004519 manufacturing process Methods 0.000 title claims description 15
- 241000894006 Bacteria Species 0.000 claims abstract description 55
- 239000000178 monomer Substances 0.000 claims abstract description 46
- 238000000034 method Methods 0.000 claims abstract description 38
- 241000252867 Cupriavidus metallidurans Species 0.000 claims abstract description 20
- 230000002906 microbiologic effect Effects 0.000 claims abstract description 5
- 239000000758 substrate Substances 0.000 claims description 34
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 18
- 238000006243 chemical reaction Methods 0.000 claims description 18
- 229910052799 carbon Inorganic materials 0.000 claims description 17
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 16
- 239000012736 aqueous medium Substances 0.000 claims description 16
- 239000002609 medium Substances 0.000 claims description 13
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 235000015097 nutrients Nutrition 0.000 claims description 10
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- 229910052757 nitrogen Inorganic materials 0.000 claims description 9
- 235000019260 propionic acid Nutrition 0.000 claims description 6
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- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical group CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims description 4
- 239000000126 substance Substances 0.000 claims description 4
- SJZRECIVHVDYJC-UHFFFAOYSA-M 4-hydroxybutyrate Chemical compound OCCCC([O-])=O SJZRECIVHVDYJC-UHFFFAOYSA-M 0.000 abstract 1
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- 150000007513 acids Chemical class 0.000 description 2
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- 239000000499 gel Substances 0.000 description 2
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 2
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- 229920001791 ((R)-3-Hydroxybutanoyl)(n-2) Polymers 0.000 description 1
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- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
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- 230000003287 optical effect Effects 0.000 description 1
- 229960003104 ornithine Drugs 0.000 description 1
- KHPXUQMNIQBQEV-UHFFFAOYSA-N oxaloacetic acid Chemical compound OC(=O)CC(=O)C(O)=O KHPXUQMNIQBQEV-UHFFFAOYSA-N 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 229940056360 penicillin g Drugs 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 229920000024 polymyxin B Polymers 0.000 description 1
- 229960005266 polymyxin b Drugs 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
- 238000005215 recombination Methods 0.000 description 1
- 102220277134 rs776745497 Human genes 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 238000013207 serial dilution Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- JXKPEJDQGNYQSM-UHFFFAOYSA-M sodium propionate Chemical compound [Na+].CCC([O-])=O JXKPEJDQGNYQSM-UHFFFAOYSA-M 0.000 description 1
- 235000010334 sodium propionate Nutrition 0.000 description 1
- 239000004324 sodium propionate Substances 0.000 description 1
- 229960003212 sodium propionate Drugs 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 230000004102 tricarboxylic acid cycle Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
- C12P7/625—Polyesters of hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/829—Alcaligenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Polyesters Or Polycarbonates (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898927794A GB8927794D0 (en) | 1989-12-08 | 1989-12-08 | Copolymer production |
| GB8927794 | 1989-12-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU6782790A AU6782790A (en) | 1991-06-13 |
| AU637657B2 true AU637657B2 (en) | 1993-06-03 |
Family
ID=10667644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU67827/90A Ceased AU637657B2 (en) | 1989-12-08 | 1990-12-07 | Co-polymer production |
Country Status (13)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU652942B2 (en) * | 1990-05-25 | 1994-09-15 | Monsanto Company | HV/HB copolymer production |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2061405B1 (es) * | 1993-05-04 | 1995-11-01 | Univ Granada | Produccion de polihidroxialcanoatos (phas) por azotobacter chroococcum pha. |
| GB9419082D0 (en) * | 1994-09-22 | 1994-11-09 | Zeneca Ltd | Copolyesters |
| US6600029B1 (en) | 1995-12-19 | 2003-07-29 | Regents Of The University Of Minnesota | Metabolic engineering of polyhydroxyalkanoate monomer synthases |
| MXPA00009561A (es) | 1998-03-30 | 2002-08-06 | Metabolix Inc | Cepas microbianas y procesos para la fabricacion de biomateriales. |
| JP4790912B2 (ja) * | 1999-05-12 | 2011-10-12 | メタボリックス，インコーポレイテッド | ポリヒドロキシアルカノエートを精製するための方法 |
| US6225438B1 (en) | 2000-01-31 | 2001-05-01 | The Procter & Gamble Company | Medium chain length PHA copolymer and process for producing same |
| EP1951875A2 (en) * | 2005-09-08 | 2008-08-06 | Meredian, Inc. | Deregulated bacteria with improved polyhydroxyalkanoate production |
| PH12014500549B1 (en) | 2011-10-25 | 2018-09-14 | Marrone Bio Innovations Inc | Chromobacterium formulations, compositions, metabolites and their uses |
| ES2606779T3 (es) | 2011-11-17 | 2017-03-27 | Bio-On S.P.A. | Procedimiento enzimático para producir copolímeros de hidroxialcanoato usando dos materias primas diferentes |
| RU2484140C1 (ru) * | 2011-12-26 | 2013-06-10 | Федеральное Государственное Автономное Образовательное Учреждение Высшего Профессионального Образования "Сибирский Федеральный Университет" | Способ получения сополимера 3-гидроксимасляной и 3-гидроксивалериановой кислот |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU560653B2 (en) * | 1981-07-07 | 1987-04-16 | Monsanto Company | 3-hydroxybutyrate polymers |
| EP0288908A2 (en) * | 1987-04-28 | 1988-11-02 | Mitsubishi Gas Chemical Company, Inc. | Process for production of a random copolymer comprising D-(-)-3-hydroxybutyrate units and D-(-)-3-hydroxyvalerate |
| AU601681B2 (en) * | 1985-05-28 | 1990-09-20 | Monsanto Company | Poly beta-hydroxybutyric acid/poly beta-hydroxyvaleric acid copolymer production |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0046344B1 (en) * | 1980-08-19 | 1985-06-19 | Imperial Chemical Industries Plc | Fermentation process |
| EP0052459B1 (en) * | 1980-11-18 | 1985-12-04 | Imperial Chemical Industries Plc | Beta-hydroxybutyrate polymers |
| US4477654A (en) * | 1981-07-07 | 1984-10-16 | Imperial Chemical Industries Plc | 3-Hydroxybutyrate polymers |
| GB8311677D0 (en) * | 1983-04-28 | 1983-06-02 | Ici Plc | Extraction process |
| US4788979A (en) * | 1986-09-23 | 1988-12-06 | American Cyanamid Company | Bioabsorbable coating for a surgical article |
| CA1313158C (en) * | 1988-11-07 | 1993-01-26 | William J. Page | Hyperproduction of poly-.beta.-hydroxybutyrate during exponential growthby mutant strains of azotobacter vinelandii |
-
1989
- 1989-12-08 GB GB898927794A patent/GB8927794D0/en active Pending
-
1990
- 1990-12-03 GB GB909026238A patent/GB9026238D0/en active Pending
- 1990-12-04 AT AT90313133T patent/ATE149204T1/de not_active IP Right Cessation
- 1990-12-04 EP EP90313133A patent/EP0431883B1/en not_active Expired - Lifetime
- 1990-12-04 DE DE69029993T patent/DE69029993T2/de not_active Expired - Fee Related
- 1990-12-06 IN IN1235DE1990 patent/IN177461B/en unknown
- 1990-12-06 ZA ZA909816A patent/ZA909816B/xx unknown
- 1990-12-07 BR BR909006231A patent/BR9006231A/pt not_active IP Right Cessation
- 1990-12-07 AU AU67827/90A patent/AU637657B2/en not_active Ceased
- 1990-12-07 NZ NZ236394A patent/NZ236394A/en unknown
- 1990-12-07 JP JP2400947A patent/JP3036851B2/ja not_active Expired - Lifetime
- 1990-12-08 KR KR1019900020175A patent/KR100223341B1/ko not_active Expired - Lifetime
- 1990-12-10 CA CA002031888A patent/CA2031888C/en not_active Expired - Fee Related
-
1993
- 1993-08-09 US US08/103,155 patent/US5364778A/en not_active Expired - Lifetime
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU560653B2 (en) * | 1981-07-07 | 1987-04-16 | Monsanto Company | 3-hydroxybutyrate polymers |
| AU601681B2 (en) * | 1985-05-28 | 1990-09-20 | Monsanto Company | Poly beta-hydroxybutyric acid/poly beta-hydroxyvaleric acid copolymer production |
| EP0288908A2 (en) * | 1987-04-28 | 1988-11-02 | Mitsubishi Gas Chemical Company, Inc. | Process for production of a random copolymer comprising D-(-)-3-hydroxybutyrate units and D-(-)-3-hydroxyvalerate |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU652942B2 (en) * | 1990-05-25 | 1994-09-15 | Monsanto Company | HV/HB copolymer production |
Also Published As
| Publication number | Publication date |
|---|---|
| GB9026238D0 (en) | 1991-01-16 |
| CA2031888A1 (en) | 1991-06-09 |
| DE69029993T2 (de) | 1997-07-10 |
| ZA909816B (en) | 1991-11-27 |
| EP0431883A3 (en) | 1991-11-06 |
| EP0431883A2 (en) | 1991-06-12 |
| JPH05236973A (ja) | 1993-09-17 |
| EP0431883B1 (en) | 1997-02-26 |
| IN177461B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1997-01-18 |
| GB8927794D0 (en) | 1990-02-14 |
| JP3036851B2 (ja) | 2000-04-24 |
| KR910012251A (ko) | 1991-08-07 |
| ATE149204T1 (de) | 1997-03-15 |
| AU6782790A (en) | 1991-06-13 |
| DE69029993D1 (de) | 1997-04-03 |
| KR100223341B1 (ko) | 1999-10-15 |
| BR9006231A (pt) | 1991-09-24 |
| NZ236394A (en) | 1993-04-28 |
| CA2031888C (en) | 2000-05-09 |
| US5364778A (en) | 1994-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Assignment registered |
Owner name: METABOLIX, INC. Free format text: FORMER OWNER WAS: MONSANTO COMPANY |
|
| PC | Assignment registered |
Owner name: METABOLIX INC. Free format text: FORMER OWNER WAS: METABOLIX, INC. |