AU617121B2 - Substituted guanidines containing a tetrazolyl moiety and their use as high potency sweetening agents - Google Patents
Substituted guanidines containing a tetrazolyl moiety and their use as high potency sweetening agents Download PDFInfo
- Publication number
- AU617121B2 AU617121B2 AU22522/88A AU2252288A AU617121B2 AU 617121 B2 AU617121 B2 AU 617121B2 AU 22522/88 A AU22522/88 A AU 22522/88A AU 2252288 A AU2252288 A AU 2252288A AU 617121 B2 AU617121 B2 AU 617121B2
- Authority
- AU
- Australia
- Prior art keywords
- compound
- mmol
- pct
- solution
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
- C07D257/06—Five-membered rings with nitrogen atoms directly attached to the ring carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D521/00—Heterocyclic compounds containing unspecified hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Plural Heterocyclic Compounds (AREA)
- Seasonings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Formation And Processing Of Food Products (AREA)
- Confectionery (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Electroplating And Plating Baths Therefor (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7474287A | 1987-07-17 | 1987-07-17 | |
| US074742 | 1987-07-17 | ||
| US10462087A | 1987-10-02 | 1987-10-02 | |
| US104620 | 1987-10-02 | ||
| US21673888A | 1988-07-12 | 1988-07-12 | |
| US216738 | 1988-07-12 | ||
| PCT/US1988/002394 WO1989000563A1 (en) | 1987-07-17 | 1988-07-14 | High potency sweetening agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2252288A AU2252288A (en) | 1989-02-13 |
| AU617121B2 true AU617121B2 (en) | 1991-11-21 |
Family
ID=27372540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU22522/88A Ceased AU617121B2 (en) | 1987-07-17 | 1988-07-14 | Substituted guanidines containing a tetrazolyl moiety and their use as high potency sweetening agents |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0299533B1 (enExample) |
| JP (1) | JPH0655730B2 (enExample) |
| KR (1) | KR970002877B1 (enExample) |
| CN (1) | CN1033624A (enExample) |
| AT (1) | ATE87915T1 (enExample) |
| AU (1) | AU617121B2 (enExample) |
| DE (1) | DE3880031T2 (enExample) |
| DK (1) | DK131589A (enExample) |
| ES (1) | ES2053633T3 (enExample) |
| FI (1) | FI891245A7 (enExample) |
| GR (1) | GR3008403T3 (enExample) |
| NO (1) | NO891097L (enExample) |
| PT (1) | PT88004B (enExample) |
| WO (1) | WO1989000563A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7067148B2 (en) | 2001-02-15 | 2006-06-27 | King Pharmaceutical Research & Development, Inc. | Stabilized pharmaceutical and thyroid hormone compositions and method of preparation |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| US9603848B2 (en) | 2007-06-08 | 2017-03-28 | Senomyx, Inc. | Modulation of chemosensory receptors and ligands associated therewith |
| WO2009035927A2 (en) * | 2007-09-13 | 2009-03-19 | Arete Therapeutics, Inc. | Bis-cyclyl substitued ureas or amides as soluble epoxide hydrolase inhibitors |
| EP2323997B1 (en) | 2008-07-31 | 2017-09-06 | Senomyx, Inc. | Processes and intermediates for making sweet taste enhancers |
| JP5468007B2 (ja) | 2008-09-10 | 2014-04-09 | 旭硝子株式会社 | 新規なプロスタグランジンｉ２誘導体 |
| CN101993432B (zh) * | 2009-08-14 | 2014-05-07 | 西南大学 | 基于咔唑的唑类查尔酮衍生物及其制备方法 |
| TWI555744B (zh) * | 2010-03-08 | 2016-11-01 | Kaken Pharma Co Ltd | Novel EP4 agonists |
| CN103156154A (zh) * | 2011-12-09 | 2013-06-19 | 味之素株式会社 | 甜味剂组合物以及饮料食品 |
| EP3593648B1 (en) | 2012-08-06 | 2021-07-14 | Firmenich Incorporated | Sweet flavor modifier |
| KR20150100830A (ko) * | 2012-12-26 | 2015-09-02 | 니혼 콘 스타치 가부시키가이샤 | 액상 감미료 조성물 |
| JO3155B1 (ar) | 2013-02-19 | 2017-09-20 | Senomyx Inc | معدِّل نكهة حلوة |
| KR20170023087A (ko) * | 2014-06-27 | 2017-03-02 | 아지노모토 가부시키가이샤 | 단맛 수용체 안타고니스트 |
| CN109890804A (zh) | 2016-05-30 | 2019-06-14 | 慕尼黑工业大学 | 作为抗细菌药物的含有脲基元的化合物及其衍生物 |
| CN107721894A (zh) * | 2016-08-12 | 2018-02-23 | 正大天晴药业集团股份有限公司 | 一种6‑芳基氨基吡啶酮甲酰胺mek抑制剂化合物的中间体的制备方法 |
| CN112703193A (zh) | 2018-08-07 | 2021-04-23 | 弗门尼舍公司 | 5-取代的4-氨基-1H-苯并[c][1,2,6]噻二嗪2,2-二氧化物及其制剂和用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3294551A (en) * | 1964-02-24 | 1966-12-27 | Lilly Co Eli | 5-carbocyclicaminotetrazole sweetening agents |
| US3515727A (en) * | 1967-04-14 | 1970-06-02 | Lilly Co Eli | Substituted tetrazole |
| US3737436A (en) * | 1968-07-05 | 1973-06-05 | Lilly Co Eli | Alpha-tetrazolyl-6-substituted tryptamine and alpha-tetrazolyl-5,6-disubstitutedtryptamine compounds |
| US3615700A (en) * | 1968-07-05 | 1971-10-26 | Lilly Co Eli | Alpha-tetrazolyl-6-substituted-tryptamine and alpha-tetrazolyl-5 6-disubstituted-tryptamine sweetening compositions and their use |
| GB1587258A (en) * | 1977-06-17 | 1981-04-01 | Gea As | Production of substituted guanidines |
| US4309446A (en) * | 1980-02-22 | 1982-01-05 | Eli Lilly And Company | 5-(Dihydroxyphenoxy)tetrazoles and use as sweeteners for medical compositions |
| US4560694A (en) * | 1982-06-04 | 1985-12-24 | Bayer Aktiengesellschaft | Fungicidal alkylene(cycloalkylene)-bis-heterocyclyl-biguanides |
| FR2533210A1 (fr) * | 1982-09-17 | 1984-03-23 | Lyon I Universite Claude | Edulcorants de synthese |
| US4680300A (en) * | 1985-01-10 | 1987-07-14 | Syntex (U.S.A.) Inc. | Anti-inflammatory guanidines |
| FR2579202B1 (fr) * | 1985-03-19 | 1988-04-29 | Univ Claude Bernard Lyon | Nouveaux composes chimiques, utilisation comme agents edulcorants et compositions contenant de tels agents |
| FR2579201B1 (fr) * | 1985-03-19 | 1987-05-07 | Bernard Lyon I Universite Clau | Composes chimiques perfectionnes, utilisation comme agents edulcorants et compositions contenant de tels agents |
| US4692513A (en) * | 1985-12-20 | 1987-09-08 | The Procter & Gamble Company | Alpha-L-aspartyl-D-heteroaromatic-substituted glycine esters and amides useful as high intensity sweeteners |
-
1988
- 1988-07-14 FI FI891245A patent/FI891245A7/fi not_active Application Discontinuation
- 1988-07-14 JP JP63506606A patent/JPH0655730B2/ja not_active Expired - Lifetime
- 1988-07-14 WO PCT/US1988/002394 patent/WO1989000563A1/en not_active Ceased
- 1988-07-14 AU AU22522/88A patent/AU617121B2/en not_active Ceased
- 1988-07-14 KR KR1019890700117A patent/KR970002877B1/ko not_active Expired - Fee Related
- 1988-07-15 PT PT88004A patent/PT88004B/pt not_active IP Right Cessation
- 1988-07-16 CN CN88106127A patent/CN1033624A/zh active Pending
- 1988-07-18 ES ES88111508T patent/ES2053633T3/es not_active Expired - Lifetime
- 1988-07-18 EP EP88111508A patent/EP0299533B1/en not_active Expired - Lifetime
- 1988-07-18 DE DE8888111508T patent/DE3880031T2/de not_active Expired - Fee Related
- 1988-07-18 AT AT88111508T patent/ATE87915T1/de not_active IP Right Cessation
-
1989
- 1989-03-14 NO NO89891097A patent/NO891097L/no unknown
- 1989-03-17 DK DK131589A patent/DK131589A/da not_active Application Discontinuation
-
1993
- 1993-07-07 GR GR920403220T patent/GR3008403T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR970002877B1 (ko) | 1997-03-12 |
| EP0299533A3 (en) | 1989-07-19 |
| CN1033624A (zh) | 1989-07-05 |
| JPH0655730B2 (ja) | 1994-07-27 |
| DE3880031D1 (de) | 1993-05-13 |
| PT88004A (pt) | 1989-06-30 |
| FI891245L (fi) | 1989-03-16 |
| EP0299533A2 (en) | 1989-01-18 |
| JPH02500371A (ja) | 1990-02-08 |
| DE3880031T2 (de) | 1993-08-19 |
| DK131589D0 (da) | 1989-03-17 |
| EP0299533B1 (en) | 1993-04-07 |
| FI891245A0 (fi) | 1989-03-16 |
| PT88004B (pt) | 1995-03-01 |
| WO1989000563A1 (en) | 1989-01-26 |
| AU2252288A (en) | 1989-02-13 |
| DK131589A (da) | 1989-03-17 |
| ATE87915T1 (de) | 1993-04-15 |
| KR890701570A (ko) | 1989-12-21 |
| GR3008403T3 (enExample) | 1993-10-29 |
| ES2053633T3 (es) | 1994-08-01 |
| NO891097D0 (no) | 1989-03-14 |
| FI891245A7 (fi) | 1989-03-16 |
| NO891097L (no) | 1989-03-14 |
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