AU597478B2 - 3-(2-haloethyl)-1,4-oxathiins and 2-(2-haloethyl)-1,4-dithiins and treatment of leukemia and tumors therewith - Google Patents

3-(2-haloethyl)-1,4-oxathiins and 2-(2-haloethyl)-1,4-dithiins and treatment of leukemia and tumors therewith Download PDF

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Publication number
AU597478B2
AU597478B2 AU12827/88A AU1282788A AU597478B2 AU 597478 B2 AU597478 B2 AU 597478B2 AU 12827/88 A AU12827/88 A AU 12827/88A AU 1282788 A AU1282788 A AU 1282788A AU 597478 B2 AU597478 B2 AU 597478B2
Authority
AU
Australia
Prior art keywords
compound
oxathiin
hydrogen
leukemia
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU12827/88A
Other languages
English (en)
Other versions
AU1282788A (en
Inventor
Walter G. Brouwer
Ethel E. Felauer
Marshal Kulka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lanxess Canada Co
Original Assignee
Uniroyal Chemical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniroyal Chemical Ltd filed Critical Uniroyal Chemical Ltd
Publication of AU1282788A publication Critical patent/AU1282788A/en
Application granted granted Critical
Publication of AU597478B2 publication Critical patent/AU597478B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08—Six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06—Six-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
AU12827/88A 1987-03-11 1988-03-09 3-(2-haloethyl)-1,4-oxathiins and 2-(2-haloethyl)-1,4-dithiins and treatment of leukemia and tumors therewith Ceased AU597478B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US2465787A 1987-03-11 1987-03-11
US024657 1987-03-11
US07/146,512 US4822813A (en) 1987-03-11 1988-01-21 3-(2-Haloalkyl)-1,4-oxathiins and 2-(2-haloalkyl)-1,4-dithiins, and treatment of leukemia and tumors therewith
US146512 2002-05-14

Publications (2)

Publication Number Publication Date
AU1282788A AU1282788A (en) 1988-09-15
AU597478B2 true AU597478B2 (en) 1990-05-31

Family

ID=26698721

Family Applications (1)

Application Number Title Priority Date Filing Date
AU12827/88A Ceased AU597478B2 (en) 1987-03-11 1988-03-09 3-(2-haloethyl)-1,4-oxathiins and 2-(2-haloethyl)-1,4-dithiins and treatment of leukemia and tumors therewith

Country Status (20)

Country Link
US (1) US4822813A (enExample)
JP (1) JPS63264580A (enExample)
AT (1) AT397089B (enExample)
AU (1) AU597478B2 (enExample)
BE (1) BE1002181A3 (enExample)
CA (1) CA1320210C (enExample)
CH (1) CH674366A5 (enExample)
DE (1) DE3808024A1 (enExample)
DK (1) DK168707B1 (enExample)
ES (1) ES2011075A6 (enExample)
FR (1) FR2612188B1 (enExample)
GB (1) GB2201958B (enExample)
GR (1) GR1000238B (enExample)
IE (1) IE61955B1 (enExample)
IL (1) IL85517A (enExample)
IT (1) IT8819726A0 (enExample)
LU (1) LU87152A1 (enExample)
NL (1) NL8800531A (enExample)
NZ (1) NZ223798A (enExample)
SE (1) SE466400B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9001327D0 (en) * 1990-01-19 1990-03-21 May & Baker Ltd New compositions of matter
HRP921128B1 (en) * 1991-10-30 1998-10-31 Sandor Garaczy Novel process for the preparation of 4-methyl-5(2-chloroethyl)-thiazole and analogues thereof
CN106278845B (zh) * 2016-05-19 2019-03-05 海正化工南通有限公司 一种3,5-二氯-2-戊酮的合成工艺
CN106565441A (zh) * 2016-11-10 2017-04-19 安徽国星生物化学有限公司 一种3,5‑二氯‑2‑戊酮的合成方法
CN106673978B (zh) * 2016-11-30 2019-06-25 湖南化工研究院有限公司 3,5-二氯-2-戊酮的连续化合成方法
CN107473949B (zh) * 2017-09-26 2020-10-02 安徽国星生物化学有限公司 一种3,5-二氯-2-戊酮的合成工艺

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3868459A (en) * 1968-05-21 1975-02-25 Aquitaine Petrole Method of killing nematodes using certain halomethyl oxathienes
US3728357A (en) * 1970-09-08 1973-04-17 Uniroyal Inc 2-(substituted-methyl)-5,6-dihydro-1,4-oxathiin-3-carboxamides
US4319003A (en) * 1980-09-26 1982-03-09 General Motors Corporation Poly(methyl methacrylate) polycarbonate block copolymers

Also Published As

Publication number Publication date
GB8804454D0 (en) 1988-03-23
IE61955B1 (en) 1994-11-30
FR2612188A1 (fr) 1988-09-16
IT8819726A0 (it) 1988-03-10
ES2011075A6 (es) 1989-12-16
DE3808024A1 (de) 1988-09-22
DK131188D0 (da) 1988-03-10
SE466400B (sv) 1992-02-10
DK168707B1 (da) 1994-05-24
JPS63264580A (ja) 1988-11-01
GR880100136A (en) 1989-01-31
ATA67688A (de) 1993-06-15
CA1320210C (en) 1993-07-13
JPH0372221B2 (enExample) 1991-11-18
CH674366A5 (enExample) 1990-05-31
GR1000238B (el) 1992-05-12
IL85517A0 (en) 1988-08-31
SE8800863D0 (sv) 1988-03-10
AU1282788A (en) 1988-09-15
LU87152A1 (fr) 1988-11-17
US4822813A (en) 1989-04-18
NL8800531A (nl) 1988-10-03
DK131188A (da) 1988-09-12
NZ223798A (en) 1989-12-21
SE8800863L (sv) 1989-09-12
AT397089B (de) 1994-01-25
IE880597L (en) 1988-09-11
GB2201958A (en) 1988-09-14
BE1002181A3 (fr) 1990-10-02
FR2612188B1 (fr) 1991-02-15
IL85517A (en) 1992-09-06
GB2201958B (en) 1990-10-10

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