AU594972B2 - N-substituted-arylalkyl and arylalkylene aminoheterocyclics as cardiovascular antihistaminic and antisecretory agents - Google Patents

N-substituted-arylalkyl and arylalkylene aminoheterocyclics as cardiovascular antihistaminic and antisecretory agents Download PDF

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Publication number
AU594972B2
AU594972B2 AU62473/86A AU6247386A AU594972B2 AU 594972 B2 AU594972 B2 AU 594972B2 AU 62473/86 A AU62473/86 A AU 62473/86A AU 6247386 A AU6247386 A AU 6247386A AU 594972 B2 AU594972 B2 AU 594972B2
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AU
Australia
Prior art keywords
acceptable salt
pharmaceutically acceptable
bis
fluorophenyl
mole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU62473/86A
Other languages
English (en)
Other versions
AU6247386A (en
Inventor
Anthony George Proakis
James Robert Shanklin Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AH Robins Co Inc
Original Assignee
AH Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AH Robins Co Inc filed Critical AH Robins Co Inc
Publication of AU6247386A publication Critical patent/AU6247386A/en
Application granted granted Critical
Publication of AU594972B2 publication Critical patent/AU594972B2/en
Assigned to A.H. ROBINS COMPANY, INCORPORATED reassignment A.H. ROBINS COMPANY, INCORPORATED Alteration of Name(s) in Register under S187 Assignors: A.H. ROBINS COMPANY, INCORPORATED
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU62473/86A 1986-01-17 1986-09-09 N-substituted-arylalkyl and arylalkylene aminoheterocyclics as cardiovascular antihistaminic and antisecretory agents Ceased AU594972B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81970186A 1986-01-17 1986-01-17
US819701 1986-01-17

Publications (2)

Publication Number Publication Date
AU6247386A AU6247386A (en) 1987-07-23
AU594972B2 true AU594972B2 (en) 1990-03-22

Family

ID=25228814

Family Applications (1)

Application Number Title Priority Date Filing Date
AU62473/86A Ceased AU594972B2 (en) 1986-01-17 1986-09-09 N-substituted-arylalkyl and arylalkylene aminoheterocyclics as cardiovascular antihistaminic and antisecretory agents

Country Status (11)

Country Link
JP (1) JPH0772171B2 (el)
KR (1) KR900005368B1 (el)
AU (1) AU594972B2 (el)
DK (1) DK347986A (el)
GR (1) GR862024B (el)
IL (1) IL78939A (el)
IN (1) IN163948B (el)
NZ (1) NZ217408A (el)
PH (3) PH23843A (el)
PT (1) PT84128B (el)
ZA (1) ZA864522B (el)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU629534B2 (en) * 1988-02-24 1992-10-08 A.H. Robins Company, Incorporated New methods and related compounds

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH23283A (en) * 1986-02-26 1989-06-30 Eisai Co Ltd Piperidine derivative, pharmaceutical composition containing the same and method of use thereof
AU629535B2 (en) * 1988-02-10 1992-10-08 A.H. Robins Company, Incorporated N-substituted-arylalkyl and arylalkylene aminoheterocyclics as cardiovascular antihistaminic and antisecretory agents
GB8825505D0 (en) * 1988-11-01 1988-12-07 Pfizer Ltd Therapeutic agents
GB8906166D0 (en) * 1989-03-17 1989-05-04 Pfizer Ltd Therapeutic agents
GB8928042D0 (en) * 1989-12-12 1990-02-14 Pfizer Ltd Muscarinic receptor antagonists
US6004980A (en) * 1990-06-01 1999-12-21 Merrell Pharmaceuticals, Inc. (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
ATE122673T1 (de) * 1990-10-10 1995-06-15 Schering Corp Pyridin- und pyridin-n-oxid-derivate von diarylmethyl- piperidinen oder piperazinen, deren zusammensetzungen und anwendung.
DE4111861A1 (de) * 1991-04-11 1992-10-15 Schwabe Willmar Gmbh & Co Benzopyranone, verfahren zu ihrer herstellung und verwendung
WO1993011108A1 (en) * 1991-11-29 1993-06-10 Zeria Pharmaceutical Co., Ltd. Piperidine derivative and medicine containing the same
US5681830A (en) * 1992-02-03 1997-10-28 Delta Pharmaceuticals, Inc. Opioid compounds
US5807858A (en) * 1996-06-05 1998-09-15 Delta Pharmaceutical, Inc. Compositions and methods for reducing respiratory depression
EP0635012B1 (en) * 1992-03-27 1996-07-10 Schering Corporation Unbridged bis-aryl carbinol derivatives, compositions and methods of use
WO1993020080A1 (en) * 1992-03-27 1993-10-14 Schering Corporation Bridged bis-aryl carbinol derivatives, compositions and methods of use
ES2149881T3 (es) 1993-07-30 2000-11-16 Delta Pharmaceuticals Inc Compuestos de piperazina usados en terapia.
JP4057088B2 (ja) * 1996-04-22 2008-03-05 株式会社カネカ ピロリジン誘導体の製造方法
US6028083A (en) * 1997-07-25 2000-02-22 Hoechst Marion Roussel, Inc. Esters of (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl) ethyl]-4-piperidinemethanol
TW200510298A (en) * 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU506432B2 (en) * 1976-08-13 1980-01-03 G. D. Searle & Co 4 ((4 Diphenylmethyl) l-piperidinyl)methyl) benzenamines

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4632925A (en) * 1985-10-07 1986-12-30 Hoffmann-La Roche Inc. N-substituted diphenylpiperidines and antiobesity use thereof
US4810713A (en) * 1985-12-20 1989-03-07 A. H. Robins Company, Incorporated Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU506432B2 (en) * 1976-08-13 1980-01-03 G. D. Searle & Co 4 ((4 Diphenylmethyl) l-piperidinyl)methyl) benzenamines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU629534B2 (en) * 1988-02-24 1992-10-08 A.H. Robins Company, Incorporated New methods and related compounds

Also Published As

Publication number Publication date
KR900005368B1 (ko) 1990-07-28
DK347986D0 (da) 1986-07-22
AU6247386A (en) 1987-07-23
DK347986A (da) 1987-07-18
KR870007131A (ko) 1987-08-17
PH24983A (en) 1990-12-26
GR862024B (en) 1986-12-24
PT84128A (en) 1987-02-01
JPH0772171B2 (ja) 1995-08-02
PT84128B (pt) 1989-05-31
IN163948B (el) 1988-12-10
ZA864522B (en) 1987-02-25
NZ217408A (en) 1990-03-27
JPS62169763A (ja) 1987-07-25
PH24904A (en) 1990-12-26
PH23843A (en) 1989-11-23
IL78939A (en) 1990-04-29
IL78939A0 (en) 1986-09-30

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