AU587031B2 - 11-B substituted steroids and process for their preparation - Google Patents

11-B substituted steroids and process for their preparation

Info

Publication number
AU587031B2
AU587031B2 AU58062/86A AU5806286A AU587031B2 AU 587031 B2 AU587031 B2 AU 587031B2 AU 58062/86 A AU58062/86 A AU 58062/86A AU 5806286 A AU5806286 A AU 5806286A AU 587031 B2 AU587031 B2 AU 587031B2
Authority
AU
Australia
Prior art keywords
preparation
substituted steroids
steroids
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU58062/86A
Other languages
English (en)
Other versions
AU5806286A (en
Inventor
Roberto D'alessio
Enrico Di Salle
Franco Faustini
Vittoria Villa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of AU5806286A publication Critical patent/AU5806286A/en
Application granted granted Critical
Publication of AU587031B2 publication Critical patent/AU587031B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0074—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU58062/86A 1985-05-31 1986-05-29 11-B substituted steroids and process for their preparation Ceased AU587031B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8513723 1985-05-31
GB858513723A GB8513723D0 (en) 1985-05-31 1985-05-31 11-beta substituted steroids

Publications (2)

Publication Number Publication Date
AU5806286A AU5806286A (en) 1986-12-04
AU587031B2 true AU587031B2 (en) 1989-08-03

Family

ID=10579949

Family Applications (1)

Application Number Title Priority Date Filing Date
AU58062/86A Ceased AU587031B2 (en) 1985-05-31 1986-05-29 11-B substituted steroids and process for their preparation

Country Status (21)

Country Link
JP (1) JPS6212796A (fr)
KR (1) KR860009035A (fr)
AU (1) AU587031B2 (fr)
BE (1) BE904846A (fr)
CH (1) CH669385A5 (fr)
DE (1) DE3617883A1 (fr)
DK (1) DK251386A (fr)
ES (1) ES8707972A1 (fr)
FI (1) FI862278A (fr)
FR (1) FR2582654B1 (fr)
GB (2) GB8513723D0 (fr)
GR (1) GR861405B (fr)
HU (1) HU197925B (fr)
IL (1) IL78957A (fr)
IT (1) IT1190014B (fr)
NL (1) NL8601387A (fr)
NZ (1) NZ216325A (fr)
PT (1) PT82665B (fr)
SE (1) SE8602449L (fr)
SU (1) SU1508963A3 (fr)
ZA (1) ZA864065B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU608831B2 (en) * 1987-04-24 1991-04-18 Akzo N.V. Novel 11-aryloestrane and 11-arylpregnane derivatives

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3878198T2 (de) * 1987-12-12 1993-06-24 Akzo Nv 11-arylsteroid-derivate.
FR2665901B2 (fr) * 1989-02-24 1994-07-29 Roussel Uclaf Nouveaux 19-nor sterouides ayant en position 11beta une chaine carbonee comportant une fonction amide, leur preparation, leur application comme medicaments.
FR2643638B1 (fr) * 1989-02-24 1991-06-14 Roussel Uclaf Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
TWI265167B (en) * 1999-11-29 2006-11-01 Akzo Nobel Nv 3-methylene steroid derivatives
DE19961219A1 (de) * 1999-12-15 2001-07-19 Jenapharm Gmbh 11beta-Phenylestratrien-Derivate mit Fluoralkylgruppen in der aromatischen Seitenkette, deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
TW200531977A (en) 2004-03-25 2005-10-01 Akzo Nobel Nv Progesterone receptor modulators

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1128787A (en) * 1966-02-18 1968-10-02 Roussel Uclaf Processes for the preparation of unsaturated 19-nor-steroids
GB1318543A (en) * 1969-07-28 1973-05-31 Roussel Uclaf 7alpha-methyl-11beta-hydroxy-gon-4-en-3-ones processes for their preparation and compounds prepared therefrom
AU5291386A (en) * 1985-02-07 1986-08-14 Schering Aktiengesellschaft 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH488682A (de) * 1965-07-30 1970-04-15 Ciba Geigy Verfahren zur Herstellung von 4,9,11-Trienen der 19-Nor-androstanreihe
FR190F (fr) * 1965-10-22
FR5913M (fr) * 1965-12-02 1968-04-01
FR2054525B1 (fr) * 1969-07-28 1973-01-12 Roussel Uclaf
FR2377418A1 (fr) * 1977-01-13 1978-08-11 Roussel Uclaf Nouveaux derives steroides 4,9-dieniques 11b-substitues, leur procede de preparation et leur application comme medicaments
ZA8231B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
FR2522328B1 (fr) * 1982-03-01 1986-02-14 Roussel Uclaf Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1128787A (en) * 1966-02-18 1968-10-02 Roussel Uclaf Processes for the preparation of unsaturated 19-nor-steroids
GB1318543A (en) * 1969-07-28 1973-05-31 Roussel Uclaf 7alpha-methyl-11beta-hydroxy-gon-4-en-3-ones processes for their preparation and compounds prepared therefrom
AU5291386A (en) * 1985-02-07 1986-08-14 Schering Aktiengesellschaft 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU608831B2 (en) * 1987-04-24 1991-04-18 Akzo N.V. Novel 11-aryloestrane and 11-arylpregnane derivatives

Also Published As

Publication number Publication date
PT82665B (pt) 1988-08-17
SE8602449D0 (sv) 1986-05-29
NZ216325A (en) 1989-01-27
CH669385A5 (fr) 1989-03-15
FR2582654A1 (fr) 1986-12-05
DK251386A (da) 1986-12-01
ZA864065B (en) 1987-01-28
SU1508963A3 (ru) 1989-09-15
GB2175905A (en) 1986-12-10
SE8602449L (sv) 1986-12-01
IT8620598A0 (it) 1986-05-28
HUT44575A (en) 1988-03-28
FI862278A0 (fi) 1986-05-29
ES8707972A1 (es) 1987-09-01
IT8620598A1 (it) 1987-11-28
AU5806286A (en) 1986-12-04
GB8612866D0 (en) 1986-07-02
JPS6212796A (ja) 1987-01-21
IL78957A0 (en) 1986-09-30
FR2582654B1 (fr) 1988-06-03
KR860009035A (ko) 1986-12-19
DK251386D0 (da) 1986-05-29
FI862278A (fi) 1986-12-01
GR861405B (en) 1986-09-26
HU197925B (en) 1989-06-28
BE904846A (fr) 1986-12-01
PT82665A (en) 1986-06-01
GB8513723D0 (en) 1985-07-03
IL78957A (en) 1990-11-29
GB2175905B (en) 1989-01-18
NL8601387A (nl) 1986-12-16
ES555298A0 (es) 1987-09-01
DE3617883A1 (de) 1986-12-04
IT1190014B (it) 1988-02-10

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