AU576924B2 - 2-piperizino-pteridine derivatives - Google Patents

2-piperizino-pteridine derivatives

Info

Publication number
AU576924B2
AU576924B2 AU51232/85A AU5123285A AU576924B2 AU 576924 B2 AU576924 B2 AU 576924B2 AU 51232/85 A AU51232/85 A AU 51232/85A AU 5123285 A AU5123285 A AU 5123285A AU 576924 B2 AU576924 B2 AU 576924B2
Authority
AU
Australia
Prior art keywords
piperizino
pteridine derivatives
pteridine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU51232/85A
Other languages
English (en)
Other versions
AU5123285A (en
Inventor
Armin Heckel
Erich Muller
Berthold Narr
Josef Nickl
Josef Roch
Hans Weisenberger
Rainer Zimmermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of AU5123285A publication Critical patent/AU5123285A/en
Application granted granted Critical
Publication of AU576924B2 publication Critical patent/AU576924B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AU51232/85A 1984-12-12 1985-12-12 2-piperizino-pteridine derivatives Ceased AU576924B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3445298 1984-12-12
DE19843445298 DE3445298A1 (de) 1984-12-12 1984-12-12 Neue pteridine, verfahren zu ihrer herstellung und deren verwendung als zwischenprodukte oder als arzneimittel

Publications (2)

Publication Number Publication Date
AU5123285A AU5123285A (en) 1986-06-19
AU576924B2 true AU576924B2 (en) 1988-09-08

Family

ID=6252576

Family Applications (1)

Application Number Title Priority Date Filing Date
AU51232/85A Ceased AU576924B2 (en) 1984-12-12 1985-12-12 2-piperizino-pteridine derivatives

Country Status (15)

Country Link
EP (1) EP0185259A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS61140585A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU576924B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1252783A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3445298A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK161327C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES8707238A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI82696C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR852996B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL77294A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO161373C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ214522A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH24451A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT81650B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA859462B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
US7345048B2 (en) 2001-06-28 2008-03-18 Pliva D.D. Heterocyclic compounds and uses thereof as D-alanyl-D-alanine ligase inhibitors
DE10202468A1 (de) * 2002-01-23 2004-09-30 Faustus Forschungs Cie. Translational Cancer Research Gmbh Pteridinderivate, Verfahren zu deren Herstellung und ihre Verwendung
DE602004009696T2 (de) * 2003-08-29 2008-08-28 4 Aza Ip Nv Immunosuppressive wirkungen von pteridinderivativen
GB2407089A (en) * 2003-10-17 2005-04-20 4 Aza Bioscience Nv Pteridine derivatives
WO2005039587A1 (en) * 2003-10-17 2005-05-06 4 Aza Bioscience Nv Heterocycle-substituted pteridine derivatives and their use in therapy
JP2007526323A (ja) * 2004-03-04 2007-09-13 ニューロジェン・コーポレーション アリールアルキルアミノ置換キナゾリン類縁体
DE102004057594A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substitueirte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057645A1 (de) * 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057618A1 (de) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057595A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
AU2006318948B2 (en) * 2005-11-22 2011-02-24 Kudos Pharmaceuticals Limited Pyrido-,pyrazo- and pyrimido-pyrimidine derivatives as mTOR inhibitors
RU2445315C2 (ru) * 2005-11-22 2012-03-20 Кудос Фармасьютиклз Лимитед ПРОИЗВОДНЫЕ ПИРИДО-, ПИРАЗО- И ПИРИМИДО-ПИРИМИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ mTOR
CA2652840C (en) 2006-05-24 2014-09-09 Boehringer Ingelheim International Gmbh 2-piperazino-6-chloro-pteridines as pde4-inhibitors for the treatment of inflammatory diseases
US9259426B2 (en) 2006-07-20 2016-02-16 Gilead Sciences, Inc. 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
US10144736B2 (en) 2006-07-20 2018-12-04 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
MX2009001946A (es) 2006-08-23 2009-03-05 Kudos Pharm Ltd Derivados de 2-metilmorfolin-pirido-, pirazo- y pirimido- pirimidina como inhibidores de mtor.
EP2303875B1 (en) 2008-06-20 2012-11-28 AstraZeneca AB Compositions with and process for methylmorpholin-subsituted pyrido[2,3-d]pyrimidines
MD3097102T2 (ro) 2015-03-04 2018-02-28 Gilead Sciences Inc Compuşi de 4,6-diamino-pirido[3,2-D]pirimidină modulatori ai receptorilor de tip Toll
WO2018045150A1 (en) 2016-09-02 2018-03-08 Gilead Sciences, Inc. 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
CN109923106B (zh) 2016-09-02 2022-09-13 吉利德科学公司 toll样受体调节剂化合物
TW202212339A (zh) 2019-04-17 2022-04-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202210480A (zh) 2019-04-17 2022-03-16 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TWI879779B (zh) 2019-06-28 2025-04-11 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3009284A (en) * 1983-07-02 1985-01-03 Dr. Karl Thomae Gmbh Piperazino substituted pteridines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159628A (en) * 1962-05-28 1964-12-01 Smith Kline French Lab Pteridine-5-oxide derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3009284A (en) * 1983-07-02 1985-01-03 Dr. Karl Thomae Gmbh Piperazino substituted pteridines

Also Published As

Publication number Publication date
FI854862A7 (fi) 1986-06-13
CA1252783A (en) 1989-04-18
IL77294A (en) 1989-02-28
PT81650A (de) 1986-01-01
DK572685D0 (da) 1985-12-11
DK161327B (da) 1991-06-24
NO161373B (no) 1989-05-02
PT81650B (pt) 1988-04-21
NO161373C (no) 1989-08-09
NO854965L (no) 1986-06-13
EP0185259A2 (de) 1986-06-25
PH24451A (en) 1990-06-25
ZA859462B (en) 1987-07-29
ES8707238A1 (es) 1987-07-16
DK572685A (da) 1986-06-13
JPS61140585A (ja) 1986-06-27
DK161327C (da) 1991-12-09
EP0185259A3 (de) 1989-03-01
GR852996B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1986-04-16
FI82696C (fi) 1991-04-10
FI82696B (fi) 1990-12-31
FI854862A0 (fi) 1985-12-10
NZ214522A (en) 1988-07-28
AU5123285A (en) 1986-06-19
DE3445298A1 (de) 1986-06-12
ES549806A0 (es) 1987-07-16

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