AU567919B2 - 7-oxabicycloheptane prostaglandin derivatives - Google Patents

7-oxabicycloheptane prostaglandin derivatives

Info

Publication number
AU567919B2
AU567919B2 AU25235/84A AU2523584A AU567919B2 AU 567919 B2 AU567919 B2 AU 567919B2 AU 25235/84 A AU25235/84 A AU 25235/84A AU 2523584 A AU2523584 A AU 2523584A AU 567919 B2 AU567919 B2 AU 567919B2
Authority
AU
Australia
Prior art keywords
prostaglandin derivatives
oxabicycloheptane prostaglandin
oxabicycloheptane
derivatives
prostaglandin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU25235/84A
Other languages
English (en)
Other versions
AU2523584A (en
Inventor
Steven E. Hall
Martin Frederick Haslanger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/474,913 external-priority patent/US4474803A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of AU2523584A publication Critical patent/AU2523584A/en
Application granted granted Critical
Publication of AU567919B2 publication Critical patent/AU567919B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU25235/84A 1983-03-14 1984-03-02 7-oxabicycloheptane prostaglandin derivatives Ceased AU567919B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US474913 1983-03-14
US06/474,913 US4474803A (en) 1983-03-14 1983-03-14 7-Oxabicycloheptane substituted thio prostaglandin analogs useful in treating platelet aggregation and bronchoconstriction
US52332083A 1983-08-15 1983-08-15
US523320 1983-08-15

Publications (2)

Publication Number Publication Date
AU2523584A AU2523584A (en) 1984-09-20
AU567919B2 true AU567919B2 (en) 1987-12-10

Family

ID=27044617

Family Applications (1)

Application Number Title Priority Date Filing Date
AU25235/84A Ceased AU567919B2 (en) 1983-03-14 1984-03-02 7-oxabicycloheptane prostaglandin derivatives

Country Status (24)

Country Link
KR (1) KR840009085A (xx)
AT (1) AT383600B (xx)
AU (1) AU567919B2 (xx)
CA (1) CA1256887A (xx)
CH (1) CH658247A5 (xx)
DD (1) DD216932A5 (xx)
DE (1) DE3409124A1 (xx)
DK (1) DK155584A (xx)
ES (1) ES8506270A1 (xx)
FI (1) FI841008A (xx)
FR (1) FR2542743B1 (xx)
GB (1) GB2136428B (xx)
GR (1) GR79881B (xx)
HU (1) HU190530B (xx)
IE (1) IE57027B1 (xx)
IL (1) IL71184A0 (xx)
IT (1) IT1173442B (xx)
LU (1) LU85249A1 (xx)
NL (1) NL8400797A (xx)
NO (1) NO840960L (xx)
NZ (1) NZ207361A (xx)
PL (1) PL246663A1 (xx)
PT (1) PT78242B (xx)
SE (1) SE8401398L (xx)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU582551B2 (en) * 1983-10-21 1989-04-06 E.R. Squibb & Sons, Inc. 7-oxabicycloheptane ethers
AU595518B2 (en) * 1985-08-01 1990-04-05 E.R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526900A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4542157A (en) * 1984-04-27 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4560698A (en) * 1984-06-04 1985-12-24 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted thio prostaglandin analogs and their use in the treatment in thrombolytic disease
US4661506A (en) * 1984-11-30 1987-04-28 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted ox prostaglandin analogs
US4588743A (en) * 1985-01-22 1986-05-13 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane-substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4607049A (en) * 1985-04-22 1986-08-19 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted thio prostaglandin analogs useful in the treatment of thrombolytic disease
US4608386A (en) * 1985-04-26 1986-08-26 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane ethers useful in the treatment of thrombotic diseases
US4611006A (en) * 1985-06-28 1986-09-09 E. R. Squibb & Sons, Inc. 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the treatment of thrombotic disease
US4673685A (en) * 1986-07-23 1987-06-16 E. R. Squibb & Sons, Inc. Hydroximic acids of 7-oxabicycloheptane substituted ethers and thioethers useful in the treatment of thrombotic disease

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7299981A (en) * 1980-07-01 1982-02-02 British Technology Group Limited Prostaglandins
AU1104183A (en) * 1981-12-23 1983-07-15 British Technology Group Limited Prostaglandins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
AU561739B2 (en) * 1981-12-23 1987-05-14 British Technology Group Limited Prostaglandins
US4549030A (en) * 1982-12-13 1985-10-22 The Upjohn Company Organic compounds and process
US4526900A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4542157A (en) * 1984-04-27 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7299981A (en) * 1980-07-01 1982-02-02 British Technology Group Limited Prostaglandins
AU1104183A (en) * 1981-12-23 1983-07-15 British Technology Group Limited Prostaglandins

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU582551B2 (en) * 1983-10-21 1989-04-06 E.R. Squibb & Sons, Inc. 7-oxabicycloheptane ethers
AU595518B2 (en) * 1985-08-01 1990-04-05 E.R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs

Also Published As

Publication number Publication date
GB2136428A (en) 1984-09-19
AU2523584A (en) 1984-09-20
ATA83484A (de) 1986-12-15
CH658247A5 (fr) 1986-10-31
AT383600B (de) 1987-07-27
IT1173442B (it) 1987-06-24
FR2542743B1 (fr) 1987-10-30
HU190530B (en) 1986-09-29
SE8401398D0 (sv) 1984-03-13
PL246663A1 (en) 1985-03-26
FI841008A (fi) 1984-09-15
PT78242A (en) 1984-04-01
ES530548A0 (es) 1985-07-01
NL8400797A (nl) 1984-10-01
SE8401398L (sv) 1984-09-15
DE3409124A1 (de) 1984-09-27
KR840009085A (ko) 1984-12-24
NO840960L (no) 1984-09-17
PT78242B (en) 1986-05-27
LU85249A1 (fr) 1984-11-14
NZ207361A (en) 1986-12-05
CA1256887A (en) 1989-07-04
FR2542743A1 (fr) 1984-09-21
DD216932A5 (de) 1985-01-02
DK155584D0 (da) 1984-03-13
IE57027B1 (en) 1992-03-25
DK155584A (da) 1984-09-15
GB8406100D0 (en) 1984-04-11
GB2136428B (en) 1986-09-10
IE840525L (en) 1984-09-14
GR79881B (xx) 1984-10-31
ES8506270A1 (es) 1985-07-01
IT8420049A0 (it) 1984-03-14
HUT34179A (en) 1985-02-28
IL71184A0 (en) 1984-06-29
FI841008A0 (fi) 1984-03-13

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