AT383600B - Verfahren zur herstellung von neuen durch 7-oxabicycloheptan substituierten prostaglandin-analogen - Google Patents
Verfahren zur herstellung von neuen durch 7-oxabicycloheptan substituierten prostaglandin-analogenInfo
- Publication number
- AT383600B AT383600B AT0083484A AT83484A AT383600B AT 383600 B AT383600 B AT 383600B AT 0083484 A AT0083484 A AT 0083484A AT 83484 A AT83484 A AT 83484A AT 383600 B AT383600 B AT 383600B
- Authority
- AT
- Austria
- Prior art keywords
- oxabicycloheptane
- producing new
- prostaglandin analogs
- analogs substituted
- new prostaglandin
- Prior art date
Links
- DYWAPFDKPAHSED-UHFFFAOYSA-N 2-cycloheptyloxepane Chemical group C1CCCCCC1C1OCCCCC1 DYWAPFDKPAHSED-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/474,913 US4474803A (en) | 1983-03-14 | 1983-03-14 | 7-Oxabicycloheptane substituted thio prostaglandin analogs useful in treating platelet aggregation and bronchoconstriction |
| US52332083A | 1983-08-15 | 1983-08-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA83484A ATA83484A (de) | 1986-12-15 |
| AT383600B true AT383600B (de) | 1987-07-27 |
Family
ID=27044617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0083484A AT383600B (de) | 1983-03-14 | 1984-03-13 | Verfahren zur herstellung von neuen durch 7-oxabicycloheptan substituierten prostaglandin-analogen |
Country Status (24)
| Country | Link |
|---|---|
| KR (1) | KR840009085A (xx) |
| AT (1) | AT383600B (xx) |
| AU (1) | AU567919B2 (xx) |
| CA (1) | CA1256887A (xx) |
| CH (1) | CH658247A5 (xx) |
| DD (1) | DD216932A5 (xx) |
| DE (1) | DE3409124A1 (xx) |
| DK (1) | DK155584A (xx) |
| ES (1) | ES8506270A1 (xx) |
| FI (1) | FI841008A (xx) |
| FR (1) | FR2542743B1 (xx) |
| GB (1) | GB2136428B (xx) |
| GR (1) | GR79881B (xx) |
| HU (1) | HU190530B (xx) |
| IE (1) | IE57027B1 (xx) |
| IL (1) | IL71184A0 (xx) |
| IT (1) | IT1173442B (xx) |
| LU (1) | LU85249A1 (xx) |
| NL (1) | NL8400797A (xx) |
| NO (1) | NO840960L (xx) |
| NZ (1) | NZ207361A (xx) |
| PL (1) | PL246663A1 (xx) |
| PT (1) | PT78242B (xx) |
| SE (1) | SE8401398L (xx) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4513103A (en) * | 1983-10-21 | 1985-04-23 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane ethers useful in the treatment of thrombolytic disease |
| US4526900A (en) * | 1984-01-26 | 1985-07-02 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
| US4542157A (en) * | 1984-04-27 | 1985-09-17 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
| US4560698A (en) * | 1984-06-04 | 1985-12-24 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted thio prostaglandin analogs and their use in the treatment in thrombolytic disease |
| US4661506A (en) * | 1984-11-30 | 1987-04-28 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane substituted ox prostaglandin analogs |
| US4588743A (en) * | 1985-01-22 | 1986-05-13 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane-substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
| US4607049A (en) * | 1985-04-22 | 1986-08-19 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane substituted thio prostaglandin analogs useful in the treatment of thrombolytic disease |
| US4608386A (en) * | 1985-04-26 | 1986-08-26 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane ethers useful in the treatment of thrombotic diseases |
| US4611006A (en) * | 1985-06-28 | 1986-09-09 | E. R. Squibb & Sons, Inc. | 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the treatment of thrombotic disease |
| US4654356A (en) * | 1985-08-01 | 1987-03-31 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs |
| US4673685A (en) * | 1986-07-23 | 1987-06-16 | E. R. Squibb & Sons, Inc. | Hydroximic acids of 7-oxabicycloheptane substituted ethers and thioethers useful in the treatment of thrombotic disease |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0113561A2 (en) * | 1982-12-13 | 1984-07-18 | The Upjohn Company | Prostaglandin intermediates, their synthesis and their conversion to prostaglandins |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4143054A (en) * | 1977-11-04 | 1979-03-06 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane- and 7-oxabicycloheptene compounds |
| ZA814307B (en) * | 1980-07-01 | 1983-02-23 | Nat Res Dev | Prostaglandins |
| EP0082646B1 (en) * | 1981-12-23 | 1989-11-15 | National Research Development Corporation | Prostaglandins |
| US4526900A (en) * | 1984-01-26 | 1985-07-02 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
| US4542157A (en) * | 1984-04-27 | 1985-09-17 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
-
1984
- 1984-03-01 CA CA000448662A patent/CA1256887A/en not_active Expired
- 1984-03-02 NZ NZ207361A patent/NZ207361A/en unknown
- 1984-03-02 AU AU25235/84A patent/AU567919B2/en not_active Ceased
- 1984-03-05 IE IE525/84A patent/IE57027B1/xx unknown
- 1984-03-06 GR GR73998A patent/GR79881B/el unknown
- 1984-03-08 GB GB08406100A patent/GB2136428B/en not_active Expired
- 1984-03-08 IL IL71184A patent/IL71184A0/xx unknown
- 1984-03-13 AT AT0083484A patent/AT383600B/de not_active IP Right Cessation
- 1984-03-13 PT PT78242A patent/PT78242B/pt unknown
- 1984-03-13 CH CH1244/84A patent/CH658247A5/fr not_active IP Right Cessation
- 1984-03-13 HU HU841001A patent/HU190530B/hu unknown
- 1984-03-13 FR FR8403835A patent/FR2542743B1/fr not_active Expired
- 1984-03-13 ES ES530548A patent/ES8506270A1/es not_active Expired
- 1984-03-13 DE DE19843409124 patent/DE3409124A1/de not_active Withdrawn
- 1984-03-13 NO NO840960A patent/NO840960L/no unknown
- 1984-03-13 NL NL8400797A patent/NL8400797A/nl not_active Application Discontinuation
- 1984-03-13 KR KR1019840001248A patent/KR840009085A/ko not_active Application Discontinuation
- 1984-03-13 DK DK155584A patent/DK155584A/da not_active IP Right Cessation
- 1984-03-13 FI FI841008A patent/FI841008A/fi not_active Application Discontinuation
- 1984-03-13 SE SE8401398A patent/SE8401398L/xx not_active Application Discontinuation
- 1984-03-14 PL PL24666384A patent/PL246663A1/xx unknown
- 1984-03-14 DD DD84260892A patent/DD216932A5/de unknown
- 1984-03-14 LU LU85249A patent/LU85249A1/fr unknown
- 1984-03-14 IT IT20049/84A patent/IT1173442B/it active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0113561A2 (en) * | 1982-12-13 | 1984-07-18 | The Upjohn Company | Prostaglandin intermediates, their synthesis and their conversion to prostaglandins |
Also Published As
| Publication number | Publication date |
|---|---|
| GB8406100D0 (en) | 1984-04-11 |
| LU85249A1 (fr) | 1984-11-14 |
| IL71184A0 (en) | 1984-06-29 |
| IE840525L (en) | 1984-09-14 |
| NO840960L (no) | 1984-09-17 |
| AU567919B2 (en) | 1987-12-10 |
| DD216932A5 (de) | 1985-01-02 |
| GB2136428A (en) | 1984-09-19 |
| DE3409124A1 (de) | 1984-09-27 |
| ATA83484A (de) | 1986-12-15 |
| KR840009085A (ko) | 1984-12-24 |
| HU190530B (en) | 1986-09-29 |
| GB2136428B (en) | 1986-09-10 |
| ES530548A0 (es) | 1985-07-01 |
| IE57027B1 (en) | 1992-03-25 |
| FI841008A (fi) | 1984-09-15 |
| FI841008A0 (fi) | 1984-03-13 |
| SE8401398L (sv) | 1984-09-15 |
| IT1173442B (it) | 1987-06-24 |
| CH658247A5 (fr) | 1986-10-31 |
| GR79881B (xx) | 1984-10-31 |
| IT8420049A0 (it) | 1984-03-14 |
| AU2523584A (en) | 1984-09-20 |
| ES8506270A1 (es) | 1985-07-01 |
| HUT34179A (en) | 1985-02-28 |
| PT78242B (en) | 1986-05-27 |
| NL8400797A (nl) | 1984-10-01 |
| CA1256887A (en) | 1989-07-04 |
| PL246663A1 (en) | 1985-03-26 |
| NZ207361A (en) | 1986-12-05 |
| DK155584A (da) | 1984-09-15 |
| FR2542743B1 (fr) | 1987-10-30 |
| FR2542743A1 (fr) | 1984-09-21 |
| SE8401398D0 (sv) | 1984-03-13 |
| PT78242A (en) | 1984-04-01 |
| DK155584D0 (da) | 1984-03-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee | ||
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |