AU563591B2 - Pyrazolo/4,3-c/pyridines - Google Patents

Pyrazolo/4,3-c/pyridines

Info

Publication number
AU563591B2
AU563591B2 AU11305/83A AU1130583A AU563591B2 AU 563591 B2 AU563591 B2 AU 563591B2 AU 11305/83 A AU11305/83 A AU 11305/83A AU 1130583 A AU1130583 A AU 1130583A AU 563591 B2 AU563591 B2 AU 563591B2
Authority
AU
Australia
Prior art keywords
pyridines
pyrazolo
neuroleptic
antihypertensive
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
AU11305/83A
Other languages
English (en)
Other versions
AU1130583A (en
Inventor
Domenico Barone
Alberto Sala
Giorgio Winters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA, Lepetit SpA filed Critical Gruppo Lepetit SpA
Publication of AU1130583A publication Critical patent/AU1130583A/en
Application granted granted Critical
Publication of AU563591B2 publication Critical patent/AU563591B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU11305/83A 1982-02-17 1983-02-10 Pyrazolo/4,3-c/pyridines Expired - Fee Related AU563591B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8204722 1982-02-17
GB8204722 1982-02-17

Publications (2)

Publication Number Publication Date
AU1130583A AU1130583A (en) 1983-08-25
AU563591B2 true AU563591B2 (en) 1987-07-16

Family

ID=10528419

Family Applications (1)

Application Number Title Priority Date Filing Date
AU11305/83A Expired - Fee Related AU563591B2 (en) 1982-02-17 1983-02-10 Pyrazolo/4,3-c/pyridines

Country Status (16)

Country Link
US (1) US4500525A (en, 2012)
EP (1) EP0086422B1 (en, 2012)
JP (1) JPS58152885A (en, 2012)
KR (1) KR900006853B1 (en, 2012)
AT (1) ATE30027T1 (en, 2012)
AU (1) AU563591B2 (en, 2012)
CA (1) CA1225646A (en, 2012)
DE (1) DE3373904D1 (en, 2012)
DK (1) DK27383A (en, 2012)
ES (3) ES8500273A1 (en, 2012)
GR (1) GR78080B (en, 2012)
IE (1) IE55156B1 (en, 2012)
IL (1) IL67785A0 (en, 2012)
NZ (1) NZ203302A (en, 2012)
PH (1) PH23645A (en, 2012)
ZA (1) ZA83628B (en, 2012)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137890A (en) * 1990-02-14 1992-08-11 Ortho Pharmaceutical Corporation 4-phenyl tetrahydropyrido(4,3-d)pyrimidines
US5264576A (en) * 1992-10-22 1993-11-23 Hoechst-Roussel Pharmaceuticals Incorporated Pyrazolo[4,3-c]pyridines which are intermediates
DE19834044A1 (de) * 1998-07-29 2000-02-03 Bayer Ag Neue substituierte Pyrazolderivate
PL213103B1 (pl) 2000-08-14 2013-01-31 Ortho Mcneil Pharm Inc Podstawiona pochodna pirazolu, jej zastosowanie i zawierajaca ja kompozycja farmaceutyczna
US20070105841A1 (en) * 2000-08-14 2007-05-10 Breitenbucher J G Method for treating allergies using substituted pyrazoles
CA2419550A1 (en) 2000-08-14 2002-02-21 Ortho-Mcneil Pharmaceutical, Inc. Substituted pyrazoles
US20050101587A9 (en) * 2000-08-14 2005-05-12 Butler Christopher R. Method for treating allergies using substituted pyrazoles
PT1309591E (pt) * 2000-08-14 2007-04-30 Ortho Mcneil Pharm Inc Pirazoles substituídos
US7332494B2 (en) 2000-08-14 2008-02-19 Janssen Pharmaceutica, N.V. Method for treating allergies using substituted pyrazoles
US20070117785A1 (en) * 2000-08-14 2007-05-24 Butler Christopher R Substituted pyrazoles and methods of treatment with substituted pyrazoles
JP2004508329A (ja) * 2000-09-06 2004-03-18 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 置換ピラゾールを使用するアレルギーの処置法
US6579896B2 (en) * 2000-09-06 2003-06-17 Ortho-Mcneil Pharmaceutical, Inc. Method for treating allergies using substituted pyrazoles
RU2286343C2 (ru) * 2001-08-10 2006-10-27 Орто-Макнейл Фармасьютикал, Инк. Замещенные пиразолы
MXPA04011956A (es) 2002-05-30 2005-03-31 Vertex Pharma Inhibidores de proteinas cinasas jak y cdk2.
AU2003244632A1 (en) * 2002-07-25 2004-02-25 Pharmacia Italia S.P.A. Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
EP2243781A1 (en) * 2003-05-30 2010-10-27 Vertex Pharmaceuticals, Inc. Pyrazolopyridine derivatives as inhibitors of JAK and CDK2 protein kinases
CA2539426C (en) * 2003-09-17 2012-07-10 Janssen Pharmaceutica, Nv Fused heterocyclic compounds
ATE546452T1 (de) 2003-09-23 2012-03-15 Vertex Pharma Pyrazolopyrrolderivate als proteinkinaseinhibitoren
KR100838692B1 (ko) 2007-07-11 2008-06-16 한국화학연구원 7-(3′,4′-디알콕시페닐)-4,5,6,7-테트라히드로피라졸로[1,5-ａ]피리미딘 화합물, 이의 제조방법 및 이를 포함하는천식 및 만성폐쇄성 폐질환을 포함한 염증관련 질환,관절염, 아토피 피부염, 암 및 뇌질환의 치료 및 예방을위한 약제학적 조성물
WO2012036997A1 (en) * 2010-09-16 2012-03-22 Schering Corporation Fused pyrazole derivatives as novel erk inhibitors
AU2011376747B2 (en) 2011-09-12 2017-03-30 Sanofi Indanyl-substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them
WO2013037736A1 (en) 2011-09-12 2013-03-21 Sanofi Indanyl-substituted 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them
KR20140077912A (ko) 2011-09-16 2014-06-24 사노피 치환된 4,5,6,7-테트라하이드로-1H-피라졸로[4,3-c]피리딘, 약물로서의 그 용도, 및 그를 포함한 약제학적 제제
MX2014003181A (es) * 2011-09-16 2015-08-05 Sanofi Sa 4,5,6,7-tetrahidro-1h-pirazolo [4,3-c] piridinas sustituidas, su uso como medicamento y preparaciones farmacéuticas que las comprenden.
KR20170118706A (ko) 2014-12-30 2017-10-25 노비라 테라퓨틱스, 인코포레이티드 B형 간염 감염을 치료하는 유도체 및 그 방법
JP7014736B2 (ja) * 2016-05-24 2022-02-01 ジェネンテック， インコーポレイテッド がんの処置のためのピラゾロピリジン誘導体
ES2900299T3 (es) 2016-06-29 2022-03-16 Novira Therapeutics Inc Derivados de diazepinona y su uso en el tratamiento de infecciones de hepatitis B
TW201806956A (zh) 2016-06-29 2018-03-01 諾維拉治療公司 二氮呯酮衍生物及治療ｂ型肝炎感染之方法
AU2018277520B2 (en) 2017-05-31 2022-03-17 Chemocentryx, Inc. 6-5 fused rings as C5a inhibitors
US10828285B2 (en) * 2017-12-22 2020-11-10 Chemocentryx, Inc. Diaryl substituted 6,5-fused ring compounds as C5aR inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852279A (en) * 1973-03-12 1974-12-03 Squibb & Sons Inc 7-substituted -3,3a,4,5,6,7-hexahydro-3-substituted-2h- pyrazolo (4,3-c)pyridines

Also Published As

Publication number Publication date
US4500525A (en) 1985-02-19
ES531980A0 (es) 1985-09-01
JPH0412269B2 (en, 2012) 1992-03-04
EP0086422B1 (en) 1987-09-30
EP0086422A3 (en) 1984-03-28
DK27383D0 (da) 1983-01-25
EP0086422A2 (en) 1983-08-24
ES519832A0 (es) 1984-10-01
GR78080B (en, 2012) 1984-09-26
DK27383A (da) 1983-08-18
KR900006853B1 (ko) 1990-09-22
ZA83628B (en) 1983-12-28
IL67785A0 (en) 1983-05-15
ATE30027T1 (de) 1987-10-15
ES8507547A1 (es) 1985-09-01
CA1225646A (en) 1987-08-18
ES8507546A1 (es) 1985-09-01
ES531981A0 (es) 1985-09-01
IE830328L (en) 1983-08-17
DE3373904D1 (en) 1987-11-05
NZ203302A (en) 1986-08-08
AU1130583A (en) 1983-08-25
KR840003636A (ko) 1984-09-15
ES8500273A1 (es) 1984-10-01
PH23645A (en) 1989-09-27
JPS58152885A (ja) 1983-09-10
IE55156B1 (en) 1990-06-20

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