AU516399B2 - Preparation of pyrrolo-benzoic acid derivatives - Google Patents

Preparation of pyrrolo-benzoic acid derivatives

Info

Publication number
AU516399B2
AU516399B2 AU31956/77A AU3195677A AU516399B2 AU 516399 B2 AU516399 B2 AU 516399B2 AU 31956/77 A AU31956/77 A AU 31956/77A AU 3195677 A AU3195677 A AU 3195677A AU 516399 B2 AU516399 B2 AU 516399B2
Authority
AU
Australia
Prior art keywords
benzoic acid
alkyl
atoms
pyrrolo
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU31956/77A
Other languages
English (en)
Other versions
AU3195677A (en
Inventor
W. ET AL Merkel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2658766A external-priority patent/DE2658766C2/de
Priority claimed from DE19772718494 external-priority patent/DE2718494A1/de
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU3195677A publication Critical patent/AU3195677A/en
Application granted granted Critical
Publication of AU516399B2 publication Critical patent/AU516399B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
AU31956/77A 1976-12-24 1977-12-23 Preparation of pyrrolo-benzoic acid derivatives Expired AU516399B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DEDE2658766 1976-12-24
DE2658766A DE2658766C2 (de) 1976-12-24 1976-12-24 3-N-Pyrrolo-5-sulfamoylbenzoesäure-Derivate und Verfahren zu ihrer Herstellung
DE19772718494 DE2718494A1 (de) 1977-04-26 1977-04-26 Verfahren zur herstellung von pyrrolo-benzoesaeure-derivaten
DEDE2718494 1977-04-26

Publications (2)

Publication Number Publication Date
AU3195677A AU3195677A (en) 1979-06-28
AU516399B2 true AU516399B2 (en) 1981-06-04

Family

ID=25771305

Family Applications (1)

Application Number Title Priority Date Filing Date
AU31956/77A Expired AU516399B2 (en) 1976-12-24 1977-12-23 Preparation of pyrrolo-benzoic acid derivatives

Country Status (22)

Country Link
US (1) US4172142A (enExample)
JP (1) JPS5379859A (enExample)
AT (1) AT371806B (enExample)
AU (1) AU516399B2 (enExample)
CA (1) CA1093565A (enExample)
CH (1) CH632996A5 (enExample)
DK (1) DK162088C (enExample)
ES (1) ES465207A1 (enExample)
FI (1) FI773906A7 (enExample)
FR (2) FR2375210A1 (enExample)
GB (2) GB1589340A (enExample)
GR (1) GR71189B (enExample)
HU (1) HU177641B (enExample)
IE (1) IE46126B1 (enExample)
IL (1) IL53673A (enExample)
IT (1) IT1089319B (enExample)
NL (1) NL7714062A (enExample)
NO (2) NO774455L (enExample)
NZ (1) NZ186094A (enExample)
PH (1) PH14409A (enExample)
PT (1) PT67449B (enExample)
SE (2) SE425487B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2917997A1 (de) * 1979-05-04 1980-11-20 Hoechst Ag Substituierte pyrrolidinyl-benzoesaeure- derivate und verfahren zu ihrer herstellung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2419970C3 (de) * 1974-04-25 1980-06-12 Hoechst Ag, 6000 Frankfurt 3-<l-Pyrrolidinyl)-4-phenoxy-5sulfamoylbenzoesäure und Verfahren zu ihrer Herstellung
CH628622A5 (de) * 1976-12-24 1982-03-15 Ciba Geigy Ag Verfahren zur herstellung von neuen in 4-stellung substituierten 3-sulfamoylbenzoesaeuren.

Also Published As

Publication number Publication date
HU177641B (en) 1981-11-28
IL53673A (en) 1986-04-29
PT67449A (de) 1978-01-01
CH632996A5 (de) 1982-11-15
IL53673A0 (en) 1978-03-10
SE7714648L (sv) 1978-06-25
IE772606L (en) 1978-06-24
FR2375210B1 (enExample) 1981-02-27
SE8202788L (sv) 1982-05-04
SE425487B (sv) 1982-10-04
AU3195677A (en) 1979-06-28
PH14409A (en) 1981-06-25
NZ186094A (en) 1979-10-25
PT67449B (de) 1979-09-20
DK577477A (da) 1978-06-25
DK162088B (da) 1991-09-16
DK162088C (da) 1992-02-24
CA1093565A (en) 1981-01-13
ES465207A1 (es) 1978-11-16
FR2383925A1 (fr) 1978-10-13
NO774455L (no) 1978-06-27
IE46126B1 (en) 1983-02-23
AT371806B (de) 1983-08-10
IT1089319B (it) 1985-06-18
ATA928077A (de) 1982-12-15
FR2375210A1 (fr) 1978-07-21
JPS5379859A (en) 1978-07-14
GR71189B (enExample) 1983-04-11
NO821761L (no) 1978-06-27
NL7714062A (nl) 1978-06-27
GB1589340A (en) 1981-05-13
GB1589339A (en) 1981-05-13
JPS638103B2 (enExample) 1988-02-19
US4172142A (en) 1979-10-23
FR2383925B1 (enExample) 1981-02-27
SE426240B (sv) 1982-12-20
FI773906A7 (fi) 1978-06-25

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