FR2383925A1 - Derives d'acide pyrrolo-benzoique et applications de ces derniers en therapeutique - Google Patents

Derives d'acide pyrrolo-benzoique et applications de ces derniers en therapeutique

Info

Publication number
FR2383925A1
FR2383925A1 FR7820499A FR7820499A FR2383925A1 FR 2383925 A1 FR2383925 A1 FR 2383925A1 FR 7820499 A FR7820499 A FR 7820499A FR 7820499 A FR7820499 A FR 7820499A FR 2383925 A1 FR2383925 A1 FR 2383925A1
Authority
FR
France
Prior art keywords
pyrrolo
benzoic acid
acid derivatives
therapeutic applications
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7820499A
Other languages
English (en)
Other versions
FR2383925B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2658766A external-priority patent/DE2658766C2/de
Priority claimed from DE19772718494 external-priority patent/DE2718494A1/de
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of FR2383925A1 publication Critical patent/FR2383925A1/fr
Application granted granted Critical
Publication of FR2383925B1 publication Critical patent/FR2383925B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)

Abstract

L'invention a pour objet des dérivés d'acide 3N-pyrrolo-benzoïque de la formule générale IV :
FR7820499A 1976-12-24 1978-07-10 Derives d'acide pyrrolo-benzoique et applications de ces derniers en therapeutique Granted FR2383925A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2658766A DE2658766C2 (de) 1976-12-24 1976-12-24 3-N-Pyrrolo-5-sulfamoylbenzoesäure-Derivate und Verfahren zu ihrer Herstellung
DE19772718494 DE2718494A1 (de) 1977-04-26 1977-04-26 Verfahren zur herstellung von pyrrolo-benzoesaeure-derivaten

Publications (2)

Publication Number Publication Date
FR2383925A1 true FR2383925A1 (fr) 1978-10-13
FR2383925B1 FR2383925B1 (fr) 1981-02-27

Family

ID=25771305

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7738494A Granted FR2375210A1 (fr) 1976-12-24 1977-12-20 Procede de preparation de derives d'acide pyrrolo-benzoique, produits obtenus et applications de ces derniers en therapeutique
FR7820499A Granted FR2383925A1 (fr) 1976-12-24 1978-07-10 Derives d'acide pyrrolo-benzoique et applications de ces derniers en therapeutique

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7738494A Granted FR2375210A1 (fr) 1976-12-24 1977-12-20 Procede de preparation de derives d'acide pyrrolo-benzoique, produits obtenus et applications de ces derniers en therapeutique

Country Status (22)

Country Link
US (1) US4172142A (fr)
JP (1) JPS5379859A (fr)
AT (1) AT371806B (fr)
AU (1) AU516399B2 (fr)
CA (1) CA1093565A (fr)
CH (1) CH632996A5 (fr)
DK (1) DK162088C (fr)
ES (1) ES465207A1 (fr)
FI (1) FI773906A (fr)
FR (2) FR2375210A1 (fr)
GB (2) GB1589340A (fr)
GR (1) GR71189B (fr)
HU (1) HU177641B (fr)
IE (1) IE46126B1 (fr)
IL (1) IL53673A (fr)
IT (1) IT1089319B (fr)
NL (1) NL7714062A (fr)
NO (2) NO774455L (fr)
NZ (1) NZ186094A (fr)
PH (1) PH14409A (fr)
PT (1) PT67449B (fr)
SE (2) SE425487B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2917997A1 (de) * 1979-05-04 1980-11-20 Hoechst Ag Substituierte pyrrolidinyl-benzoesaeure- derivate und verfahren zu ihrer herstellung

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2419970A1 (de) * 1974-04-25 1975-11-13 Hoechst Ag Tertiaere cyclische amine und verfahren zu ihrer herstellung
FR2375211A1 (fr) * 1976-12-24 1978-07-21 Ciba Geigy Ag Nouveaux acides sulfamoylbenzoiques, leur preparation et leur application en tant que medicaments

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2419970A1 (de) * 1974-04-25 1975-11-13 Hoechst Ag Tertiaere cyclische amine und verfahren zu ihrer herstellung
FR2375211A1 (fr) * 1976-12-24 1978-07-21 Ciba Geigy Ag Nouveaux acides sulfamoylbenzoiques, leur preparation et leur application en tant que medicaments

Also Published As

Publication number Publication date
NO821761L (no) 1978-06-27
PH14409A (en) 1981-06-25
IE772606L (en) 1978-06-24
SE8202788L (sv) 1982-05-04
DK162088B (da) 1991-09-16
GB1589340A (en) 1981-05-13
SE7714648L (sv) 1978-06-25
JPS5379859A (en) 1978-07-14
NO774455L (no) 1978-06-27
ATA928077A (de) 1982-12-15
JPS638103B2 (fr) 1988-02-19
SE425487B (sv) 1982-10-04
NL7714062A (nl) 1978-06-27
IL53673A (en) 1986-04-29
IE46126B1 (en) 1983-02-23
HU177641B (en) 1981-11-28
GR71189B (fr) 1983-04-11
FI773906A (fi) 1978-06-25
FR2375210A1 (fr) 1978-07-21
IT1089319B (it) 1985-06-18
AU3195677A (en) 1979-06-28
CA1093565A (fr) 1981-01-13
IL53673A0 (en) 1978-03-10
DK577477A (da) 1978-06-25
SE426240B (sv) 1982-12-20
US4172142A (en) 1979-10-23
AT371806B (de) 1983-08-10
ES465207A1 (es) 1978-11-16
FR2375210B1 (fr) 1981-02-27
CH632996A5 (de) 1982-11-15
DK162088C (da) 1992-02-24
NZ186094A (en) 1979-10-25
FR2383925B1 (fr) 1981-02-27
AU516399B2 (en) 1981-06-04
PT67449A (de) 1978-01-01
PT67449B (de) 1979-09-20
GB1589339A (en) 1981-05-13

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Legal Events

Date Code Title Description
ST Notification of lapse