AU2019418498A1 - Compositions and methods for carrying out assay measurements - Google Patents

Compositions and methods for carrying out assay measurements Download PDF

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Publication number
AU2019418498A1
AU2019418498A1 AU2019418498A AU2019418498A AU2019418498A1 AU 2019418498 A1 AU2019418498 A1 AU 2019418498A1 AU 2019418498 A AU2019418498 A AU 2019418498A AU 2019418498 A AU2019418498 A AU 2019418498A AU 2019418498 A1 AU2019418498 A1 AU 2019418498A1
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AU
Australia
Prior art keywords
composition
ecl
bdea
tris
chloride ion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2019418498A
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English (en)
Inventor
George Sigal
Alexander K. TUCKER-SCHWARTZ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meso Scale Technologies LLC
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Meso Scale Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meso Scale Technologies LLC filed Critical Meso Scale Technologies LLC
Publication of AU2019418498A1 publication Critical patent/AU2019418498A1/en
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/30—Electrochemically active labels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
AU2019418498A 2019-01-03 2019-12-23 Compositions and methods for carrying out assay measurements Pending AU2019418498A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962787892P 2019-01-03 2019-01-03
US62/787,892 2019-01-03
PCT/US2019/068293 WO2020142313A1 (en) 2019-01-03 2019-12-23 Compositions and methods for carrying out assay measurements

Publications (1)

Publication Number Publication Date
AU2019418498A1 true AU2019418498A1 (en) 2021-07-15

Family

ID=69187986

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2019418498A Pending AU2019418498A1 (en) 2019-01-03 2019-12-23 Compositions and methods for carrying out assay measurements

Country Status (12)

Country Link
US (3) US12203937B2 (https=)
EP (1) EP3906412A1 (https=)
JP (2) JP7516388B2 (https=)
KR (2) KR102897648B1 (https=)
CN (1) CN113366313A (https=)
AU (1) AU2019418498A1 (https=)
CA (1) CA3125146A1 (https=)
IL (1) IL284558A (https=)
SG (1) SG11202106924VA (https=)
TW (1) TWI871299B (https=)
WO (1) WO2020142313A1 (https=)
ZA (1) ZA202104404B (https=)

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CN120098057A (zh) 2019-03-01 2025-06-06 中尺度技术有限责任公司 用于免疫方法的被电化学发光标记的探针、使用这类探针的方法和包含这类探针的试剂盒
US20240018571A1 (en) 2020-05-19 2024-01-18 Meso Scale Technologies, Llc. Methods, compositions, and kits for nucleic acid detection
EP4176263A1 (en) 2020-07-01 2023-05-10 Meso Scale Technologies, LLC Compositions and methods for assay measurements
US20220145363A1 (en) 2020-11-09 2022-05-12 Meso Scale Technologies, Llc. Methods and kits for detecting tau
US20240287572A1 (en) 2021-04-16 2024-08-29 Meso Scale Technologies, Llc. Methods, compositions, and kits for detecting hydrolase enzyme activity
AU2022304570A1 (en) 2021-06-28 2024-01-18 Meso Scale Technologies, Llc. Methods, compositions, and kits for assay signal amplification
US20250244342A1 (en) 2022-04-07 2025-07-31 Meso Scale Technologies, Llc. Methods and kits for assessing alzheimer's disease
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WO2025260043A1 (en) 2024-06-14 2025-12-18 Meso Scale Technologies, Llc. Methods and kits for measuring three or more tau epitopes
WO2026039455A1 (en) 2024-08-13 2026-02-19 Meso Scale Technologies, Llc. Detection of nucleic acids

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Also Published As

Publication number Publication date
JP7516388B2 (ja) 2024-07-16
TW202438888A (zh) 2024-10-01
JP7805391B2 (ja) 2026-01-23
US20220018846A1 (en) 2022-01-20
US20220373554A1 (en) 2022-11-24
US11927592B2 (en) 2024-03-12
TW202043771A (zh) 2020-12-01
TWI871299B (zh) 2025-02-01
SG11202106924VA (en) 2021-07-29
KR20210146884A (ko) 2021-12-06
KR20250037585A (ko) 2025-03-17
US12203937B2 (en) 2025-01-21
CA3125146A1 (en) 2020-07-09
ZA202104404B (en) 2025-09-25
JP2022515917A (ja) 2022-02-22
CN113366313A (zh) 2021-09-07
KR102897648B1 (ko) 2025-12-08
WO2020142313A1 (en) 2020-07-09
IL284558A (en) 2021-08-31
US20250102511A1 (en) 2025-03-27
JP2024105355A (ja) 2024-08-06
EP3906412A1 (en) 2021-11-10

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