IL284558A - Compositions and methods for carrying out assay measurements - Google Patents
Compositions and methods for carrying out assay measurementsInfo
- Publication number
- IL284558A IL284558A IL284558A IL28455821A IL284558A IL 284558 A IL284558 A IL 284558A IL 284558 A IL284558 A IL 284558A IL 28455821 A IL28455821 A IL 28455821A IL 284558 A IL284558 A IL 284558A
- Authority
- IL
- Israel
- Prior art keywords
- compositions
- methods
- performing analysis
- analysis measurements
- measurements
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/30—Electrochemically active labels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962787892P | 2019-01-03 | 2019-01-03 | |
| PCT/US2019/068293 WO2020142313A1 (en) | 2019-01-03 | 2019-12-23 | Compositions and methods for carrying out assay measurements |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL284558A true IL284558A (en) | 2021-08-31 |
Family
ID=69187986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL284558A IL284558A (en) | 2019-01-03 | 2021-07-01 | Compositions and methods for carrying out assay measurements |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US12203937B2 (https=) |
| EP (1) | EP3906412A1 (https=) |
| JP (2) | JP7516388B2 (https=) |
| KR (2) | KR102897648B1 (https=) |
| CN (1) | CN113366313A (https=) |
| AU (1) | AU2019418498A1 (https=) |
| CA (1) | CA3125146A1 (https=) |
| IL (1) | IL284558A (https=) |
| SG (1) | SG11202106924VA (https=) |
| TW (1) | TWI871299B (https=) |
| WO (1) | WO2020142313A1 (https=) |
| ZA (1) | ZA202104404B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12480940B2 (en) | 2018-05-17 | 2025-11-25 | Meso Scale Technologies, Llc. | Methods for isolating surface marker displaying agents |
| EP3861124A1 (en) | 2018-10-02 | 2021-08-11 | Osler Diagnostics Limited | Methods for immunoassays using electrochemical measurement |
| CN120098057A (zh) | 2019-03-01 | 2025-06-06 | 中尺度技术有限责任公司 | 用于免疫方法的被电化学发光标记的探针、使用这类探针的方法和包含这类探针的试剂盒 |
| US20240018571A1 (en) | 2020-05-19 | 2024-01-18 | Meso Scale Technologies, Llc. | Methods, compositions, and kits for nucleic acid detection |
| EP4176263A1 (en) | 2020-07-01 | 2023-05-10 | Meso Scale Technologies, LLC | Compositions and methods for assay measurements |
| US20220145363A1 (en) | 2020-11-09 | 2022-05-12 | Meso Scale Technologies, Llc. | Methods and kits for detecting tau |
| US20240287572A1 (en) | 2021-04-16 | 2024-08-29 | Meso Scale Technologies, Llc. | Methods, compositions, and kits for detecting hydrolase enzyme activity |
| AU2022304570A1 (en) | 2021-06-28 | 2024-01-18 | Meso Scale Technologies, Llc. | Methods, compositions, and kits for assay signal amplification |
| US20250244342A1 (en) | 2022-04-07 | 2025-07-31 | Meso Scale Technologies, Llc. | Methods and kits for assessing alzheimer's disease |
| AU2023408595A1 (en) | 2022-12-20 | 2025-07-17 | Meso Scale Technologies, Llc. | Assay methods and kits |
| WO2025260043A1 (en) | 2024-06-14 | 2025-12-18 | Meso Scale Technologies, Llc. | Methods and kits for measuring three or more tau epitopes |
| WO2026039455A1 (en) | 2024-08-13 | 2026-02-19 | Meso Scale Technologies, Llc. | Detection of nucleic acids |
Family Cites Families (63)
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|---|---|---|---|---|
| US5238808A (en) | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US5310687A (en) | 1984-10-31 | 1994-05-10 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US6316607B1 (en) | 1986-04-30 | 2001-11-13 | Igen International, Inc. | Electrochemiluminescent assays |
| US6165729A (en) | 1986-04-30 | 2000-12-26 | Hyperion Catalysis International, Inc. | Electrochemiluminescent reaction utilizing amine-derived reductant |
| US6451225B1 (en) | 1986-04-30 | 2002-09-17 | Igen International, Inc. | Electrochemiluminescent reaction utilizing amine-derived reductant |
| US5591581A (en) | 1986-04-30 | 1997-01-07 | Igen, Inc. | Electrochemiluminescent rhenium moieties and methods for their use |
| US5147806A (en) | 1988-04-29 | 1992-09-15 | Igen, Inc. | Method and apparatus for conducting electrochemiluminescence measurements |
| US5935779A (en) | 1988-11-03 | 1999-08-10 | Igen International Inc. | Methods for improved particle electrochemiluminescence assay |
| US5308754A (en) | 1988-03-21 | 1994-05-03 | Kankare Jouko J | Electrogenerated luminescence in solution |
| US5093268A (en) | 1988-04-28 | 1992-03-03 | Igen, Inc. | Apparatus for conducting a plurality of simultaneous measurements of electrochemiluminescent phenomena |
| US5705402A (en) | 1988-11-03 | 1998-01-06 | Igen International, Inc. | Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets |
| JPH076913B2 (ja) | 1988-11-03 | 1995-01-30 | イゲン，インコーポレーテッド | アミン誘導還元剤を利用する電気化学発光反応 |
| US5324457A (en) | 1989-10-02 | 1994-06-28 | Board Of Regents, The University Of Tx System | Devices and methods for generating electrogenerated chemiluminescence |
| US5776672A (en) | 1990-09-28 | 1998-07-07 | Kabushiki Kaisha Toshiba | Gene detection method |
| JPH0534345A (ja) | 1991-02-19 | 1993-02-09 | Tdk Corp | 化学発光を利用する抗原・抗体の測定方法 |
| ZA929351B (en) | 1991-12-11 | 1993-06-04 | Igen Inc | Electrochemiluminescent label for DNA assays. |
| US5656504A (en) * | 1992-10-26 | 1997-08-12 | Pharmacia Biosensor Ab | Method of preventing undesired binding in solid phase assays |
| WO1994025853A1 (de) * | 1993-05-03 | 1994-11-10 | Boehringer Mannheim Gmbh | Elektrochemilumineszenzverfahren |
| US5786141A (en) | 1994-08-26 | 1998-07-28 | Bard; Allen J. | Electrogenerated chemiluminescence labels for analysis and/or referencing |
| US5744367A (en) * | 1994-11-10 | 1998-04-28 | Igen International, Inc. | Magnetic particle based electrochemiluminescent detection apparatus and method |
| US5866434A (en) | 1994-12-08 | 1999-02-02 | Meso Scale Technology | Graphitic nanotubes in luminescence assays |
| US5643713A (en) | 1995-06-07 | 1997-07-01 | Liang; Pam | Electrochemiluminescent monitoring of compounds |
| US5641623A (en) | 1995-01-04 | 1997-06-24 | Martin; Mark T. | Electrochemiluminescence assay |
| AU4756296A (en) | 1995-01-06 | 1996-07-24 | Igen, Inc. | Electrogenerated chemiluminescence through enhanced particle luminescence |
| US5993740A (en) | 1995-01-20 | 1999-11-30 | Hitachi, Ltd. | Immunoassay method and analyzer using magnetic particles |
| US6207369B1 (en) | 1995-03-10 | 2001-03-27 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
| JPH11502617A (ja) | 1995-03-10 | 1999-03-02 | メソ スケール テクノロジーズ，エルエルシー | 多重アレイの多重特異的な電気化学発光試験 |
| US6140045A (en) | 1995-03-10 | 2000-10-31 | Meso Scale Technologies | Multi-array, multi-specific electrochemiluminescence testing |
| US5679519A (en) | 1995-05-09 | 1997-10-21 | Oprandy; John J. | Multi-label complex for enhanced sensitivity in electrochemiluminescence assay |
| US6319670B1 (en) | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
| US5589136A (en) | 1995-06-20 | 1996-12-31 | Regents Of The University Of California | Silicon-based sleeve devices for chemical reactions |
| GB9606850D0 (en) | 1996-04-01 | 1996-06-05 | Univ Liverpool | An assay system and novel labelled compounds for use therwith |
| FR2764381A1 (fr) | 1997-06-09 | 1998-12-11 | Univ De Neuchatel | Detecteur electrochimioluminescent |
| US6413783B1 (en) | 1997-09-18 | 2002-07-02 | Meso Scale Technologies, Llc | Assay sonication apparatus and methodology |
| US6200531B1 (en) | 1998-05-11 | 2001-03-13 | Igen International, Inc. | Apparatus for carrying out electrochemiluminescence test measurements |
| EP0962773A1 (en) | 1998-06-03 | 1999-12-08 | Mark Howard Jones | Electrochemical based assay processes instrument and labels |
| GB9815042D0 (en) | 1998-07-10 | 1998-09-09 | Imperial College | Detector |
| JP2001021560A (ja) * | 1999-07-07 | 2001-01-26 | Nitto Denko Corp | 免疫クロマト測定法 |
| US6136268A (en) | 1999-08-17 | 2000-10-24 | Orion Diagnostica | Method for luminescence measurements |
| DK1412725T3 (en) | 2001-06-29 | 2019-03-25 | Meso Scale Technologies Llc | Multi-well plates for LUMINESCENSE TEST MEASUREMENTS |
| US6808939B2 (en) | 2001-06-29 | 2004-10-26 | Igen International, Inc. | ECL labels having improved non-specific binding properties, methods of using and kits containing the same |
| AU2008200361B2 (en) | 2001-09-10 | 2010-06-17 | Meso Scale Technologies, Llc. | Assay buffer, compositions containing the same, and methods of using the same |
| WO2003023380A1 (en) | 2001-09-10 | 2003-03-20 | Meso Scale Technologies, Llc | Assay buffer, compositions containing the same, and methods of using the same |
| US20080261243A1 (en) | 2004-10-06 | 2008-10-23 | Wellstat Biologics Corporation | Detection of Elevated Levels of Her-2/Neu Protein on Circulating Cancer Cells and Treatment |
| US20090291920A1 (en) | 2006-04-18 | 2009-11-26 | Wellstat Biologics Corporation | Detection of steroid receptors on circulating carcinoma cells and treatment |
| CN101532961B (zh) | 2009-04-10 | 2011-07-20 | 中国科学院长春应用化学研究所 | 一种电化学发光检测的方法 |
| JP2011047923A (ja) | 2009-07-27 | 2011-03-10 | Panasonic Corp | リポソーム組成物及びその製造方法並びにそれを用いたアナライトの分析方法 |
| US20120190586A1 (en) | 2009-10-15 | 2012-07-26 | Waters Marcey L | Synthetic Receptors for Identification of Protein Posttranslation Modifications |
| EP4060325B1 (en) | 2009-12-07 | 2024-08-21 | Meso Scale Technologies, LLC. | Assay cartridge reader |
| BR112013007614B1 (pt) * | 2010-10-25 | 2020-12-29 | F. Hoffmann-La Roche Ag | método para medir um analito, composição reagente, mistura reagente, uso de uma composição reagente, uso de uma amida de ácido carbônico e kit |
| CA2824404C (en) | 2011-01-06 | 2023-01-03 | Meso Scale Technologies, Llc | Assay cartridges for pcr analysis and methods of use thereof |
| CN102680456B (zh) * | 2011-03-16 | 2015-07-08 | 北京联众泰克科技有限公司 | 一种电化学发光免疫测定方法 |
| ES2621507T3 (es) | 2012-08-02 | 2017-07-04 | F. Hoffmann-La Roche Ag | Nuevos complejos a base de iridio para EQL |
| JP2015526427A (ja) | 2012-08-02 | 2015-09-10 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | Ｅｃｌ用の新規イリジウムベース錯体 |
| CA2904181A1 (en) | 2013-03-13 | 2014-10-09 | Anahit Aghvanyan | Sandwich immunoassay comprising anchoring reagent |
| US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
| US20140367278A1 (en) * | 2013-06-12 | 2014-12-18 | PharmOptima, LLC | Methods for Detecting Survival Motor Neuron (SMN) Protein in Whole Blood or Cerebral Spinal Fluid |
| EP3143401A4 (en) | 2014-05-15 | 2017-10-11 | Meso Scale Technologies, LLC | Improved assay methods |
| WO2017153574A1 (en) | 2016-03-11 | 2017-09-14 | Roche Diagnostics Gmbh | Branched-chain amines in electrochemiluminescence detection |
| CN106124753B (zh) | 2016-07-08 | 2018-03-06 | 广州东林生物科技有限公司 | 电化学发光缓冲液及清洗液 |
| CN106526183A (zh) * | 2016-09-21 | 2017-03-22 | 宁波大学 | 一种电位分辨双肿瘤标志物的电化学发光免疫传感器的制备方法及其应用 |
| CN109444116A (zh) | 2018-10-17 | 2019-03-08 | 江西中洪博元生物技术有限公司 | 一种增强型ecl化学发光试剂 |
| EP4176263A1 (en) | 2020-07-01 | 2023-05-10 | Meso Scale Technologies, LLC | Compositions and methods for assay measurements |
-
2019
- 2019-12-23 AU AU2019418498A patent/AU2019418498A1/en active Pending
- 2019-12-23 SG SG11202106924VA patent/SG11202106924VA/en unknown
- 2019-12-23 WO PCT/US2019/068293 patent/WO2020142313A1/en not_active Ceased
- 2019-12-23 EP EP19842531.6A patent/EP3906412A1/en active Pending
- 2019-12-23 US US17/264,489 patent/US12203937B2/en active Active
- 2019-12-23 KR KR1020217024461A patent/KR102897648B1/ko active Active
- 2019-12-23 KR KR1020257006837A patent/KR20250037585A/ko active Pending
- 2019-12-23 JP JP2021538813A patent/JP7516388B2/ja active Active
- 2019-12-23 CN CN201980091030.9A patent/CN113366313A/zh active Pending
- 2019-12-23 CA CA3125146A patent/CA3125146A1/en active Pending
- 2019-12-31 TW TW108148610A patent/TWI871299B/zh active
-
2021
- 2021-06-25 ZA ZA2021/04404A patent/ZA202104404B/en unknown
- 2021-07-01 IL IL284558A patent/IL284558A/en unknown
-
2022
- 2022-07-20 US US17/813,722 patent/US11927592B2/en active Active
-
2024
- 2024-04-25 JP JP2024071628A patent/JP7805391B2/ja active Active
- 2024-12-06 US US18/971,325 patent/US20250102511A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP7516388B2 (ja) | 2024-07-16 |
| TW202438888A (zh) | 2024-10-01 |
| JP7805391B2 (ja) | 2026-01-23 |
| US20220018846A1 (en) | 2022-01-20 |
| US20220373554A1 (en) | 2022-11-24 |
| US11927592B2 (en) | 2024-03-12 |
| TW202043771A (zh) | 2020-12-01 |
| TWI871299B (zh) | 2025-02-01 |
| AU2019418498A1 (en) | 2021-07-15 |
| SG11202106924VA (en) | 2021-07-29 |
| KR20210146884A (ko) | 2021-12-06 |
| KR20250037585A (ko) | 2025-03-17 |
| US12203937B2 (en) | 2025-01-21 |
| CA3125146A1 (en) | 2020-07-09 |
| ZA202104404B (en) | 2025-09-25 |
| JP2022515917A (ja) | 2022-02-22 |
| CN113366313A (zh) | 2021-09-07 |
| KR102897648B1 (ko) | 2025-12-08 |
| WO2020142313A1 (en) | 2020-07-09 |
| US20250102511A1 (en) | 2025-03-27 |
| JP2024105355A (ja) | 2024-08-06 |
| EP3906412A1 (en) | 2021-11-10 |
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