AU2019310600A1 - Method for treating epilepsy - Google Patents
Method for treating epilepsy Download PDFInfo
- Publication number
- AU2019310600A1 AU2019310600A1 AU2019310600A AU2019310600A AU2019310600A1 AU 2019310600 A1 AU2019310600 A1 AU 2019310600A1 AU 2019310600 A AU2019310600 A AU 2019310600A AU 2019310600 A AU2019310600 A AU 2019310600A AU 2019310600 A1 AU2019310600 A1 AU 2019310600A1
- Authority
- AU
- Australia
- Prior art keywords
- fenfluramine
- norfenfluramine
- epilepsy
- compound
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/15—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
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- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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- A—HUMAN NECESSITIES
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/14—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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| US9549909B2 (en) | 2013-05-03 | 2017-01-24 | The Katholieke Universiteit Leuven | Method for the treatment of dravet syndrome |
| CA3007286A1 (en) | 2015-12-22 | 2017-06-29 | Zogenix International Limited | Fenfluramine compositions and methods of preparing the same |
| EP3393470B1 (en) | 2015-12-22 | 2021-01-20 | Zogenix International Limited | Metabolism resistant fenfluramine analogs and methods of using the same |
| MX2019001799A (es) | 2016-08-24 | 2019-06-13 | Zogenix International Ltd | Formulacion para inhibir la formacion de agonistas de 5-ht2b y metodos de utilizacion de la misma. |
| JP7383012B2 (ja) * | 2018-08-31 | 2023-11-17 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | ヘテロアリール置換スルホンアミド化合物、およびナトリウムチャネル阻害剤としてのその使用 |
| EA202191079A1 (ru) | 2018-11-19 | 2021-09-20 | Зодженикс Интернэшнл Лимитед | Способы лечения синдрома ретта с применением фенфлурамина |
| EP3999570A1 (en) * | 2019-07-18 | 2022-05-25 | Basf Se | Allophanate based dispersing agent |
| US11612574B2 (en) | 2020-07-17 | 2023-03-28 | Zogenix International Limited | Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) |
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| CN118873517A (zh) * | 2024-07-05 | 2024-11-01 | 上海柯西医药科技发展有限公司 | 大麻二酚与5-ht2b受体激动剂的组合的用途 |
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| US4326525A (en) | 1980-10-14 | 1982-04-27 | Alza Corporation | Osmotic device that improves delivery properties of agent in situ |
| ES2157330T3 (es) * | 1994-06-03 | 2001-08-16 | Thejmde Trust | Composicion que comprende aril-alquil-amina meta substituida, usos terapeuticos y diagnosticos. |
| AU741482B2 (en) | 1997-05-07 | 2001-11-29 | Allergan Pharmaceuticals International Limited | Intravaginal drug delivery devices for the administration of testosterone and testosterone precursors |
| US6591909B1 (en) | 2001-12-20 | 2003-07-15 | Halliburton Energy Services, Inc. | Whey protein retarder |
| US9549909B2 (en) * | 2013-05-03 | 2017-01-24 | The Katholieke Universiteit Leuven | Method for the treatment of dravet syndrome |
| AU2016222804C1 (en) * | 2015-02-25 | 2021-10-14 | The Regents Of The University Of California | 5HT agonists for treating disorders |
| JP6668045B2 (ja) * | 2015-05-15 | 2020-03-18 | ゾゲニクス インターナショナル リミテッド | ドラベ症候群を処置するための選択的５−ｈｔ受容体アゴニストおよびアンタゴニスト |
| JP2017057188A (ja) * | 2015-09-14 | 2017-03-23 | ゾゲニクス インターナショナル リミテッド | 特別な形態のてんかんの併用療法 |
| GB201715919D0 (en) * | 2017-09-29 | 2017-11-15 | Gw Res Ltd | use of cannabinoids in the treatment of epilepsy |
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2019
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- 2019-07-26 WO PCT/US2019/043765 patent/WO2020023923A1/en not_active Ceased
- 2019-07-26 EA EA202190369A patent/EA202190369A1/ru unknown
- 2019-07-26 AU AU2019310600A patent/AU2019310600A1/en not_active Abandoned
- 2019-07-26 SG SG11202100682YA patent/SG11202100682YA/en unknown
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- 2019-07-26 MA MA053329A patent/MA53329A/fr unknown
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2021
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|---|---|
| CL2021000196A1 (es) | 2021-12-31 |
| MA53329A (fr) | 2022-03-02 |
| JP2021530541A (ja) | 2021-11-11 |
| ES2988130T3 (es) | 2024-11-19 |
| IL280128A (en) | 2021-03-01 |
| EP3829558C0 (en) | 2024-07-03 |
| BR112021001135A2 (pt) | 2021-04-20 |
| SG11202100682YA (en) | 2021-02-25 |
| EA202190369A1 (ru) | 2021-06-10 |
| WO2020023923A1 (en) | 2020-01-30 |
| PE20211065A1 (es) | 2021-06-09 |
| KR20210061332A (ko) | 2021-05-27 |
| MX2021000987A (es) | 2021-06-15 |
| CN112930175A (zh) | 2021-06-08 |
| EP3829558B1 (en) | 2024-07-03 |
| PH12021550176A1 (en) | 2021-10-11 |
| US20200030260A1 (en) | 2020-01-30 |
| EP3829558A1 (en) | 2021-06-09 |
| CO2021002087A2 (es) | 2021-04-30 |
| CA3106031A1 (en) | 2020-01-30 |
| CR20210095A (es) | 2021-06-01 |
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