AU2018212017B2 - Tumor selective TATA -box and CAAT-box mutants - Google Patents

Tumor selective TATA -box and CAAT-box mutants Download PDF

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Publication number
AU2018212017B2
AU2018212017B2 AU2018212017A AU2018212017A AU2018212017B2 AU 2018212017 B2 AU2018212017 B2 AU 2018212017B2 AU 2018212017 A AU2018212017 A AU 2018212017A AU 2018212017 A AU2018212017 A AU 2018212017A AU 2018212017 B2 AU2018212017 B2 AU 2018212017B2
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cancer
seq
box
recombinant adenovirus
promoter
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AU2018212017A1 (en
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Farah Hedjran
Christopher Larson
Bryan T. Oronsky
Tony R. REID
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Epicentrx Inc
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Epicentrx Inc
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AU2018212017A 2017-01-30 2018-01-30 Tumor selective TATA -box and CAAT-box mutants Ceased AU2018212017B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762452075P 2017-01-30 2017-01-30
US62/452,075 2017-01-30
PCT/US2018/016025 WO2018140970A1 (en) 2017-01-30 2018-01-30 Tumor selective tata-box and caat-box mutants

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Publication Number Publication Date
AU2018212017A1 AU2018212017A1 (en) 2019-08-15
AU2018212017B2 true AU2018212017B2 (en) 2024-11-28

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AU2018212017A Ceased AU2018212017B2 (en) 2017-01-30 2018-01-30 Tumor selective TATA -box and CAAT-box mutants

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US (2) US20190352669A1 (cg-RX-API-DMAC10.html)
EP (1) EP3573632B1 (cg-RX-API-DMAC10.html)
JP (1) JP7242534B2 (cg-RX-API-DMAC10.html)
KR (2) KR102607220B1 (cg-RX-API-DMAC10.html)
CN (1) CN110741081B (cg-RX-API-DMAC10.html)
AU (1) AU2018212017B2 (cg-RX-API-DMAC10.html)
BR (1) BR112019015514A2 (cg-RX-API-DMAC10.html)
CA (1) CA3052086A1 (cg-RX-API-DMAC10.html)
EA (1) EA201991806A1 (cg-RX-API-DMAC10.html)
IL (1) IL268289B2 (cg-RX-API-DMAC10.html)
MX (1) MX428450B (cg-RX-API-DMAC10.html)
SG (1) SG11201906976YA (cg-RX-API-DMAC10.html)
WO (1) WO2018140970A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201905070B (cg-RX-API-DMAC10.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
ES2899913T3 (es) 2014-09-24 2022-03-15 Salk Inst For Biological Studi Virus tumorales oncolíticos y métodos de uso
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
EP3390645B1 (en) 2016-02-23 2022-09-14 Salk Institute for Biological Studies Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
AU2017375633C1 (en) 2016-12-12 2023-04-27 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
AU2018253088B2 (en) 2017-04-10 2024-09-19 Epicentrx, Inc. Method for producing recombinant virus
BR112020019942A2 (pt) 2018-04-09 2021-01-26 Salk Institute For Biological Studies composições de adenovírus oncolítico com propriedades de replicação aprimoradas
WO2024015876A1 (en) 2022-07-13 2024-01-18 Epicentrx, Inc. Adenoviral vectors encapsulated in cationic liposomes, and preparation and use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1190901A (en) * 1999-09-30 2001-04-30 Trustees Of The University Of Pennsylvania, The Replication selective adenoviruses for use in cancer therapy
CA2442670A1 (en) * 2001-04-13 2002-10-24 The Trustees Of The University Of Pennsylvania Method of treating or retarding the development of blindness
CN1597939A (zh) * 2001-11-15 2005-03-23 杭州中肽生化有限公司 多功能抗癌重组腺病毒
CN101319215B (zh) * 2008-07-01 2010-12-22 郑骏年 人肿瘤特异性Ki67基因启动子
FI20090030A0 (fi) * 2009-02-02 2009-02-02 Akseli Eetu Hemminki Onkolyyttiset virukset
DK2403951T3 (en) * 2009-03-02 2016-01-11 Univ California Tumor-selective E1a and E1b adenoviral mutants
US9404090B2 (en) * 2011-11-24 2016-08-02 Viromed Co., Ltd. Adenovirus producing novel cell line and the use thereof
FI123955B (en) 2011-11-25 2014-01-15 Oncos Therapeutics Ltd Oncolytic adenovirus
US20140350087A9 (en) * 2012-03-22 2014-11-27 Halozyme, Inc. Oncovector Nucleic Acid Molecules and Methods of Use
DK3552615T3 (da) 2014-07-16 2022-02-14 Transgene Onkolytisk virus til ekspression af immun-checkpoint-modulatorer
KR102702230B1 (ko) * 2017-05-26 2024-09-03 에피센트알엑스, 인코포레이티드 트랜스진을 보유하는 재조합 아데노바이러스

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EP3573632A1 (en) 2019-12-04
KR102880548B1 (ko) 2025-11-05
IL268289A (en) 2019-09-26
ZA201905070B (en) 2024-12-18
EP3573632C0 (en) 2024-08-07
JP2020505046A (ja) 2020-02-20
IL268289B1 (en) 2025-05-01
IL268289B2 (en) 2025-09-01
KR20230164231A (ko) 2023-12-01
KR102607220B1 (ko) 2023-12-01
EP3573632A4 (en) 2020-09-23
EP3573632B1 (en) 2024-08-07
AU2018212017A1 (en) 2019-08-15
CN110741081B (zh) 2024-07-23
EA201991806A1 (ru) 2020-02-13
BR112019015514A2 (pt) 2020-04-07
CN110741081A (zh) 2020-01-31
US20250388930A1 (en) 2025-12-25
MX428450B (es) 2025-11-13
WO2018140970A1 (en) 2018-08-02
MX2019008922A (es) 2020-01-20
SG11201906976YA (en) 2019-08-27
KR20190128633A (ko) 2019-11-18
JP7242534B2 (ja) 2023-03-20
US20190352669A1 (en) 2019-11-21
CA3052086A1 (en) 2018-08-02

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