CN110741081B - 肿瘤选择性tata盒和caat盒突变体 - Google Patents

肿瘤选择性tata盒和caat盒突变体 Download PDF

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CN110741081B
CN110741081B CN201880021788.0A CN201880021788A CN110741081B CN 110741081 B CN110741081 B CN 110741081B CN 201880021788 A CN201880021788 A CN 201880021788A CN 110741081 B CN110741081 B CN 110741081B
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cancer
nucleotides
recombinant adenovirus
cells
deletion
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CN110741081A (zh
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托尼·R·雷德
布莱恩·T·奥兰斯基
法拉·海德兰
克里斯托弗·拉森
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Epicentrx Inc
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CN201880021788.0A 2017-01-30 2018-01-30 肿瘤选择性tata盒和caat盒突变体 Active CN110741081B (zh)

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US201762452075P 2017-01-30 2017-01-30
US62/452,075 2017-01-30
PCT/US2018/016025 WO2018140970A1 (en) 2017-01-30 2018-01-30 Tumor selective tata-box and caat-box mutants

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EP (1) EP3573632B1 (cg-RX-API-DMAC10.html)
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SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
ES2899913T3 (es) 2014-09-24 2022-03-15 Salk Inst For Biological Studi Virus tumorales oncolíticos y métodos de uso
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
EP3390645B1 (en) 2016-02-23 2022-09-14 Salk Institute for Biological Studies Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
AU2017375633C1 (en) 2016-12-12 2023-04-27 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
AU2018253088B2 (en) 2017-04-10 2024-09-19 Epicentrx, Inc. Method for producing recombinant virus
BR112020019942A2 (pt) 2018-04-09 2021-01-26 Salk Institute For Biological Studies composições de adenovírus oncolítico com propriedades de replicação aprimoradas
WO2024015876A1 (en) 2022-07-13 2024-01-18 Epicentrx, Inc. Adenoviral vectors encapsulated in cationic liposomes, and preparation and use thereof

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KR102880548B1 (ko) 2025-11-05
IL268289A (en) 2019-09-26
ZA201905070B (en) 2024-12-18
EP3573632C0 (en) 2024-08-07
JP2020505046A (ja) 2020-02-20
IL268289B1 (en) 2025-05-01
IL268289B2 (en) 2025-09-01
KR20230164231A (ko) 2023-12-01
AU2018212017B2 (en) 2024-11-28
KR102607220B1 (ko) 2023-12-01
EP3573632A4 (en) 2020-09-23
EP3573632B1 (en) 2024-08-07
AU2018212017A1 (en) 2019-08-15
EA201991806A1 (ru) 2020-02-13
BR112019015514A2 (pt) 2020-04-07
CN110741081A (zh) 2020-01-31
US20250388930A1 (en) 2025-12-25
MX428450B (es) 2025-11-13
WO2018140970A1 (en) 2018-08-02
MX2019008922A (es) 2020-01-20
SG11201906976YA (en) 2019-08-27
KR20190128633A (ko) 2019-11-18
JP7242534B2 (ja) 2023-03-20
US20190352669A1 (en) 2019-11-21
CA3052086A1 (en) 2018-08-02

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