AU2018208103B2 - An agent for promoting angiogenesis and methods and uses thereof - Google Patents
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- AU2018208103B2 AU2018208103B2 AU2018208103A AU2018208103A AU2018208103B2 AU 2018208103 B2 AU2018208103 B2 AU 2018208103B2 AU 2018208103 A AU2018208103 A AU 2018208103A AU 2018208103 A AU2018208103 A AU 2018208103A AU 2018208103 B2 AU2018208103 B2 AU 2018208103B2
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- YFDSDPIBEUFTMI-UHFFFAOYSA-N tribromoethanol Chemical compound OCC(Br)(Br)Br YFDSDPIBEUFTMI-UHFFFAOYSA-N 0.000 description 1
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- 125000004417 unsaturated alkyl group Chemical group 0.000 description 1
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- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
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- 230000003612 virological effect Effects 0.000 description 1
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Classifications
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/515—Angiogenesic factors; Angiogenin
-
- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
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- Epidemiology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
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- Immunology (AREA)
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- Dermatology (AREA)
- Hematology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
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| US201762446030P | 2017-01-13 | 2017-01-13 | |
| US62/446,030 | 2017-01-13 | ||
| PCT/CA2018/050022 WO2018129618A1 (en) | 2017-01-13 | 2018-01-11 | An agent for promoting angiogenesis and methods and uses thereof |
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| AU2018208103A1 AU2018208103A1 (en) | 2019-07-11 |
| AU2018208103B2 true AU2018208103B2 (en) | 2021-10-28 |
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| US (2) | US11384130B2 (zh) |
| EP (1) | EP3568409B1 (zh) |
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| KR (1) | KR102612117B1 (zh) |
| CN (1) | CN110225922B (zh) |
| AU (1) | AU2018208103B2 (zh) |
| BR (1) | BR112019014492A2 (zh) |
| CA (1) | CA3049727C (zh) |
| IL (1) | IL267996B (zh) |
| MX (1) | MX2019008421A (zh) |
| WO (1) | WO2018129618A1 (zh) |
| ZA (1) | ZA201905262B (zh) |
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| JP2021155406A (ja) * | 2020-03-27 | 2021-10-07 | ロート製薬株式会社 | 育毛促進用組成物 |
| JP7344406B2 (ja) * | 2020-04-06 | 2023-09-13 | バソミューン セラピューティクス， インコーポレイテッド | コロナウイルス治療薬および処置方法 |
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| WO2008049227A1 (en) * | 2006-10-27 | 2008-05-02 | Sunnybrook Health Sciences Center | Multimeric tie 2 agonists and uses thereof in stimulating angiogenesis |
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| US7838497B2 (en) * | 2006-12-13 | 2010-11-23 | Susavion Biosciences, Inc. | Pro-angiogenic peptides |
| CA2701612A1 (en) * | 2007-10-05 | 2009-04-09 | Takeda Pharmaceutical Company Limited | Neuromedin u derivative |
| US8858940B2 (en) * | 2008-12-10 | 2014-10-14 | Ablynx N.V. | Amino acid sequences directed against the Angiopoietin/Tie system and polypeptides comprising the same for the treatment of diseases and disorders related to angiogenesis |
| CA2797247C (en) | 2010-04-28 | 2019-10-22 | Sunnybrook Health Sciences Centre | Methods and uses of tie2 binding and/or activating agents |
| ES2875957T3 (es) * | 2012-12-20 | 2021-11-11 | Amgen Inc | Agonistas del receptor APJ y usos de los mismos |
| EP2983695B1 (en) * | 2013-04-11 | 2019-05-29 | Sunnybrook Research Institute | Methods, uses and compositions of tie2 agonists |
| CN105813650A (zh) * | 2013-11-06 | 2016-07-27 | 施特姆森特克斯股份有限公司 | 新型抗-密蛋白抗体和使用方法 |
| JP6553605B2 (ja) * | 2013-11-22 | 2019-07-31 | ジェムバックス アンド カエル カンパニー，リミティド | 血管新生抑制活性を有するペプチド、及びそれを含む組成物 |
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Patent Citations (1)
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| WO2008049227A1 (en) * | 2006-10-27 | 2008-05-02 | Sunnybrook Health Sciences Center | Multimeric tie 2 agonists and uses thereof in stimulating angiogenesis |
Also Published As
| Publication number | Publication date |
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| EP3568409A1 (en) | 2019-11-20 |
| RU2019123694A (ru) | 2021-02-15 |
| CN110225922A (zh) | 2019-09-10 |
| IL267996A (en) | 2019-09-26 |
| RU2019123694A3 (zh) | 2021-06-30 |
| CA3049727C (en) | 2022-10-04 |
| MX2019008421A (es) | 2019-12-16 |
| US20220372095A1 (en) | 2022-11-24 |
| JP7107968B2 (ja) | 2022-07-27 |
| EP3568409A4 (en) | 2020-11-25 |
| KR20190104352A (ko) | 2019-09-09 |
| AU2018208103A1 (en) | 2019-07-11 |
| EP3568409B1 (en) | 2022-12-21 |
| BR112019014492A2 (pt) | 2020-02-18 |
| WO2018129618A1 (en) | 2018-07-19 |
| IL267996B (en) | 2022-05-01 |
| KR102612117B1 (ko) | 2023-12-12 |
| US11384130B2 (en) | 2022-07-12 |
| JP2020506223A (ja) | 2020-02-27 |
| ZA201905262B (en) | 2021-08-25 |
| US20190359670A1 (en) | 2019-11-28 |
| CA3049727A1 (en) | 2018-07-19 |
| CN110225922B (zh) | 2023-09-12 |
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