AU2017390821B2 - Predictive focus tracking apparatus and methods - Google Patents

Predictive focus tracking apparatus and methods Download PDF

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Publication number
AU2017390821B2
AU2017390821B2 AU2017390821A AU2017390821A AU2017390821B2 AU 2017390821 B2 AU2017390821 B2 AU 2017390821B2 AU 2017390821 A AU2017390821 A AU 2017390821A AU 2017390821 A AU2017390821 A AU 2017390821A AU 2017390821 B2 AU2017390821 B2 AU 2017390821B2
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AU
Australia
Prior art keywords
sample
stage
focus
location
optical
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AU2017390821A
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English (en)
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AU2017390821A1 (en
Inventor
Ashkan Arianpour
John Bailey
Dustin Blair
Xiangling Chen (Steve)
Danilo Condello
Stanley S. Hong
Simon Prince
Merek C. Siu
Chunhong Zhou (Allen)
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Illumina Inc
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Illumina Inc
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Publication date
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Publication of AU2017390821A1 publication Critical patent/AU2017390821A1/en
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Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/006—Optical details of the image generation focusing arrangements; selection of the plane to be imaged
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/245—Devices for focusing using auxiliary sources, detectors
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/10—Beam splitting or combining systems
    • G02B27/16—Beam splitting or combining systems used as aids for focusing
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/02—Mountings, adjusting means, or light-tight connections, for optical elements for lenses
    • G02B7/04—Mountings, adjusting means, or light-tight connections, for optical elements for lenses with mechanism for focusing or varying magnification
    • G02B7/09—Mountings, adjusting means, or light-tight connections, for optical elements for lenses with mechanism for focusing or varying magnification adapted for automatic focusing or varying magnification
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/02—Mountings, adjusting means, or light-tight connections, for optical elements for lenses
    • G02B7/04—Mountings, adjusting means, or light-tight connections, for optical elements for lenses with mechanism for focusing or varying magnification
    • G02B7/10—Mountings, adjusting means, or light-tight connections, for optical elements for lenses with mechanism for focusing or varying magnification by relative axial movement of several lenses, e.g. of varifocal objective lens
    • G02B7/102—Mountings, adjusting means, or light-tight connections, for optical elements for lenses with mechanism for focusing or varying magnification by relative axial movement of several lenses, e.g. of varifocal objective lens controlled by a microcomputer

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Microscoopes, Condenser (AREA)
  • Automatic Focus Adjustment (AREA)
  • Health & Medical Sciences (AREA)
  • Radar Systems Or Details Thereof (AREA)
  • Studio Devices (AREA)
  • Lens Barrels (AREA)
  • Immunology (AREA)
  • Focusing (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Prostheses (AREA)
AU2017390821A 2017-01-05 2017-12-22 Predictive focus tracking apparatus and methods Active AU2017390821B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762442947P 2017-01-05 2017-01-05
US62/442,947 2017-01-05
GB1704770.5 2017-03-24
GBGB1704770.5A GB201704770D0 (en) 2017-01-05 2017-03-24 Predictive focus tracking apparatus and methods
PCT/IB2017/058383 WO2018127769A1 (en) 2017-01-05 2017-12-22 Predictive focus tracking apparatus and methods

Publications (2)

Publication Number Publication Date
AU2017390821A1 AU2017390821A1 (en) 2018-11-22
AU2017390821B2 true AU2017390821B2 (en) 2021-10-28

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017390821A Active AU2017390821B2 (en) 2017-01-05 2017-12-22 Predictive focus tracking apparatus and methods

Country Status (17)

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US (2) US11054624B2 (enExample)
EP (1) EP3566088B1 (enExample)
JP (1) JP7050701B2 (enExample)
KR (1) KR102551459B1 (enExample)
CN (1) CN109313329B (enExample)
AU (1) AU2017390821B2 (enExample)
BR (1) BR112018076996B1 (enExample)
CA (1) CA3022894C (enExample)
GB (1) GB201704770D0 (enExample)
IL (2) IL262707B2 (enExample)
MX (1) MX2019007874A (enExample)
MY (1) MY195238A (enExample)
RU (1) RU2710004C1 (enExample)
SA (1) SA518400567B1 (enExample)
SG (1) SG11201811328PA (enExample)
TW (1) TWI772348B (enExample)
WO (1) WO2018127769A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201704770D0 (en) * 2017-01-05 2017-05-10 Illumina Inc Predictive focus tracking apparatus and methods
AU2018353924A1 (en) 2017-12-29 2019-07-18 Clear Labs, Inc. Automated priming and library loading device
NL2020618B1 (en) * 2018-01-12 2019-07-18 Illumina Inc Real time controller switching
JP6960352B2 (ja) * 2018-02-20 2021-11-05 株式会社日立ハイテク ステージ装置、及び荷電粒子線装置
US20230088338A1 (en) 2021-09-10 2023-03-23 Illumina, Inc. Sequencer focus quality metrics and focus tracking for periodically patterned surfaces
WO2023049047A1 (en) 2021-09-27 2023-03-30 Beckman Coulter, Inc. Adjustable mounting apparatus
TW202336423A (zh) 2021-10-01 2023-09-16 美商伊路米納有限公司 用於傳輸光之設備及方法
CN115086563B (zh) * 2022-07-27 2022-11-15 南方科技大学 基于SerialEM的单颗粒数据收集方法和装置
CN115576075B (zh) * 2022-11-21 2023-03-14 上海隐冠半导体技术有限公司 一种自动对焦系统和方法
CN120457383A (zh) * 2022-12-09 2025-08-08 深圳华大智造科技股份有限公司 对焦控制方法及相关设备
US12452530B2 (en) 2023-12-20 2025-10-21 Illumina, Inc. Intelligent sample tilt adjustment with zones having variable size
CN119395852B (zh) * 2024-12-31 2025-05-02 江苏慕藤光精密光学仪器有限公司 一种激光自动跟焦方法、装置及设备

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150130920A1 (en) * 2012-05-02 2015-05-14 Leica Biosystems Imaging, Inc. Real-time focusing in line scan imaging

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2696044B2 (ja) * 1992-07-14 1998-01-14 株式会社ミツトヨ 合焦検出方法、これを用いた非接触変位測定方法及び装置
DE10101624A1 (de) * 2001-01-16 2002-07-18 Zeiss Carl Jena Gmbh Anordnung zur Scharfeinstellung für Mikroskope
CN101546575B (zh) * 2001-01-30 2012-11-07 松下电器产业株式会社 备有可形变镜子的信息装置
DE10127284A1 (de) * 2001-06-05 2002-12-12 Zeiss Carl Jena Gmbh Autofokussiereinrichtung für ein optisches Gerät
JP3990177B2 (ja) * 2002-03-29 2007-10-10 独立行政法人放射線医学総合研究所 顕微鏡装置
US6924929B2 (en) 2002-03-29 2005-08-02 National Institute Of Radiological Sciences Microscope apparatus
US7725018B2 (en) * 2006-08-01 2010-05-25 Canon Kabushiki Kaisha Focus control apparatus, image sensing apparatus and focus control method
US8878923B2 (en) 2007-08-23 2014-11-04 General Electric Company System and method for enhanced predictive autofocusing
EP3067729B1 (en) 2007-09-03 2020-09-23 Nikon Corporation Automatic focusing device and microscope
US8084969B2 (en) * 2007-10-01 2011-12-27 Allegro Microsystems, Inc. Hall-effect based linear motor controller
DE102008018864B4 (de) 2008-04-15 2022-01-05 Carl Zeiss Microscopy Gmbh Mikroskop mit Haltefokus-Steuerung
JP5228878B2 (ja) 2008-12-17 2013-07-03 株式会社リコー カップリングレンズ、照明装置、及び電子機器
CN102639989B (zh) * 2009-11-06 2014-12-10 赛博光学公司 具有自适应聚焦的高速光学检查系统
EP2383600B1 (en) 2010-04-30 2013-02-20 CellaVision AB Method, apparatus, and computer program product for focus prediction
DE102011082756A1 (de) 2011-09-15 2013-03-21 Leica Microsystems (Schweiz) Ag Autofokussierverfahren und -einrichtung für ein Mikroskop
WO2013138911A1 (en) * 2012-03-23 2013-09-26 Huron Technologies International Inc. Slide scanner with dynamic focus and specimen tilt and method of operation
CN105008975B (zh) * 2013-01-17 2018-06-26 浜松光子学株式会社 图像取得装置以及图像取得装置的聚焦方法
CN105378538B (zh) * 2013-07-18 2019-05-31 文塔纳医疗系统公司 用于多频谱成像的自动聚焦方法和系统
US9134523B2 (en) * 2013-07-19 2015-09-15 Hong Kong Applied Science and Technology Research Institute Company Limited Predictive focusing for image scanning systems
CN103399397B (zh) * 2013-07-19 2015-11-18 香港应用科技研究院有限公司 用于图像扫描系统的预测聚焦
US8809809B1 (en) * 2013-09-27 2014-08-19 Hong Kong Applied Science and Technology Research Institute Company Limited Apparatus and method for focusing in fluorescence microscope
US9444995B2 (en) 2013-10-11 2016-09-13 Mitutoyo Corporation System and method for controlling a tracking autofocus (TAF) sensor in a machine vision inspection system
CN103592754B (zh) 2013-11-07 2016-03-09 麦克奥迪实业集团有限公司 一种数字切片实时扫描自动聚焦跟踪方法
JP6306724B2 (ja) * 2014-01-09 2018-04-04 ザイゴ コーポレーションＺｙｇｏ Ｃｏｒｐｏｒａｔｉｏｎ 非球面およびその他の非平坦面のトポグラフィの測定
US9546962B2 (en) * 2014-02-12 2017-01-17 Kla-Tencor Corporation Multi-spot scanning collection optics
WO2015133176A1 (ja) * 2014-03-05 2015-09-11 株式会社 日立ハイテクノロジーズ 顕微分光装置
JP6031731B2 (ja) 2014-07-18 2016-11-24 レーザーテック株式会社 検査装置及びオートフォーカス方法
US10455137B2 (en) * 2014-07-28 2019-10-22 Orbotech Ltd. Auto-focus system
US10025084B2 (en) * 2014-10-08 2018-07-17 Biotek Instruments, Inc. Autofocus algorithm for microscopy system based on cross-correlation
JP2016156950A (ja) 2015-02-24 2016-09-01 キヤノン株式会社 自動焦点調節装置およびその制御方法
MX388995B (es) * 2015-06-25 2025-03-20 Native Microbials Inc Métodos, aparatos y sistemas para analizar cepas de microorganismos de comunidades heterogéneas complejas, predecir e indentificar sus relaciones funcionales e interacciones y seleccionar y sintetizar conjuntos microbianos basados en estos.
GB201704770D0 (en) * 2017-01-05 2017-05-10 Illumina Inc Predictive focus tracking apparatus and methods

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150130920A1 (en) * 2012-05-02 2015-05-14 Leica Biosystems Imaging, Inc. Real-time focusing in line scan imaging

Also Published As

Publication number Publication date
EP3566088A1 (en) 2019-11-13
BR112018076996A2 (pt) 2019-04-02
BR112018076996B1 (pt) 2022-02-22
RU2710004C1 (ru) 2019-12-23
US20210294083A1 (en) 2021-09-23
US11977213B2 (en) 2024-05-07
CN109313329B (zh) 2021-11-09
SG11201811328PA (en) 2019-01-30
JP7050701B2 (ja) 2022-04-08
KR102551459B1 (ko) 2023-07-04
AU2017390821A1 (en) 2018-11-22
EP3566088B1 (en) 2024-01-31
IL262707B2 (en) 2023-09-01
CA3022894A1 (en) 2018-07-12
JP2020505625A (ja) 2020-02-20
WO2018127769A1 (en) 2018-07-12
NZ747882A (en) 2021-02-26
IL301850A (en) 2023-06-01
KR20190095110A (ko) 2019-08-14
IL262707B1 (en) 2023-05-01
US20180188514A1 (en) 2018-07-05
TWI772348B (zh) 2022-08-01
EP3566088C0 (en) 2024-01-31
MY195238A (en) 2023-01-11
IL301850B1 (en) 2025-03-01
CN109313329A (zh) 2019-02-05
IL262707A (en) 2018-12-31
TW201841020A (zh) 2018-11-16
IL301850B2 (en) 2025-07-01
GB201704770D0 (en) 2017-05-10
CA3022894C (en) 2020-10-27
SA518400567B1 (ar) 2022-03-20
US11054624B2 (en) 2021-07-06
EP3566088A4 (en) 2020-08-12
MX2019007874A (es) 2019-11-05

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